Mitochondrial Dysfunction in Diabetes: From Molecular Mechanisms to Functional Significance and Therapeutic Opportunities

Development of Mitochondria-targeted Aromatic-cationic Peptides for Neurodegenerative Diseases

(2010) Hazel H. Szeto   Annals of the New York Academy of Sciences

N-acetylcysteine versus AScorbic acid for Preventing contrast-Induced nephropathy in patients with renal insufficiency undergoing coronary angiography

(2009) Sang-Ho Jo et al.   AMERICAN HEART JOURNAL

Pioglitazone Improves Cardiac Function and Alters Myocardial Substrate Metabolism Without Affecting Cardiac Triglyceride Accumulation and High-Energy Phosphate Metabolism in Patients With Well-Controlled Type 2 Diabetes Mellitus

(2009) Rutger W. van der Meer et al.   CIRCULATION

PGC-1α, SIRT1 and AMPK, an energy sensing network that controls energy expenditure

(2009) Carles Cantó et al.   CURRENT OPINION IN LIPIDOLOGY

High Incidence of Metabolically Active Brown Adipose Tissue in Healthy Adult Humans: Effects of Cold Exposure and Adiposity

(2009) M. Saito et al.   DIABETES

Mitochondrial nitric oxide synthase: current concepts and controversies

(2009) Zsombor Lacza   Frontiers in Bioscience-Landmark

Absence of Nitric-oxide Synthase in Sequentially Purified Rat Liver Mitochondria

(2009) Priya Venkatakrishnan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans

(2009) Ethan J. Anderson et al.   JOURNAL OF CLINICAL INVESTIGATION

Functional Brown Adipose Tissue in Healthy Adults

(2009) Kirsi A. Virtanen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cold-Activated Brown Adipose Tissue in Healthy Men

(2009) Wouter D. van Marken Lichtenbelt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification and Importance of Brown Adipose Tissue in Adult Humans

(2009) Aaron M. Cypess et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mitochondrial Targeted Coenzyme Q, Superoxide, and Fuel Selectivity in Endothelial Cells

(2009) Brian D. Fink et al.   PLoS One

Reduced heart size and increased myocardial fuel substrate oxidation in ACC2 mutant mice

(2008) M. Faadiel Essop et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The sensitivity of pancreatic β-cells to mitochondrial injuries triggered by lipotoxicity and oxidative stress

(2008) Ning Li et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Diabetes-induced up-regulation of uncoupling protein-2 results in increased mitochondrial uncoupling in kidney proximal tubular cells

(2008) Malou Friederich et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

On the role of uncoupling protein-2 in pancreatic beta cells

(2008) Charles Affourtit et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mitochondria—A Nexus for Aging, Calorie Restriction, and Sirtuins?

(2008) Leonard Guarente   CELL

Type 1 diabetes: can exercise impair the autoimmune event? TheL-arginine/glutamine coupling hypothesis

(2008) Maurício da Silva Krause et al.   CELL BIOCHEMISTRY AND FUNCTION

Impact of mitochondrial calcium on the coupling of metabolism to insulin secretion in the pancreatic β-cell

(2008) A WIEDERKEHR et al.   CELL CALCIUM

Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance

(2008) Timothy R. Koves et al.   Cell Metabolism

Resveratrol Delays Age-Related Deterioration and Mimics Transcriptional Aspects of Dietary Restriction without Extending Life Span

(2008) Kevin J. Pearson et al.   Cell Metabolism

Heme Oxygenase-1 and Carbon Monoxide in Vascular Pathobiology

(2008) Jozef Dulak et al.   CIRCULATION

Role of Mitochondrial Dysfunction in Insulin Resistance

(2008) Jeong-a Kim et al.   CIRCULATION RESEARCH

Mitochondrial dysfunction, insulin resistance, and type 2 diabetes mellitus

(2008) Muhammad A. Abdul-Ghani et al.   Current Diabetes Reports

m.3243A>G Mutation in Mitochondrial DNA Leads to Decreased Insulin Sensitivity in Skeletal Muscle and to Progressive  -Cell Dysfunction

(2008) M. M. Lindroos et al.   DIABETES

Malonyl CoenzymeA Decarboxylase Regulates Lipid and Glucose Metabolism in Human Skeletal Muscle

(2008) K. Bouzakri et al.   DIABETES

Hyperglycemia-Induced Reactive Oxygen Species Toxicity to Endothelial Cells Is Dependent on Paracrine Mediators

(2008) J. V. Busik et al.   DIABETES

Treatment of Obese Diabetic Mice With a Heme Oxygenase Inducer Reduces Visceral and Subcutaneous Adiposity, Increases Adiponectin Levels, and Improves Insulin Sensitivity and Glucose Tolerance

(2008) M. Li et al.   DIABETES

Type 1 Diabetic Akita Mouse Hearts Are Insulin Sensitive but Manifest Structurally Abnormal Mitochondria That Remain Coupled Despite Increased Uncoupling Protein 3

(2008) H. Bugger et al.   DIABETES

Minireview: Mitochondrial Energetics and Insulin Resistance

(2008) Anthony E. Civitarese et al.   ENDOCRINOLOGY

Superoxide and Respiratory Coupling in Mitochondria of Insulin-Deficient Diabetic Rats

(2008) Judith A. Herlein et al.   ENDOCRINOLOGY

Signaling mechanisms in skeletal muscle: Acute responses and chronic adaptations to exercise

(2008) Katja S.C. Röckl et al.   IUBMB LIFE

Essential Role for Uncoupling Protein-3 in Mitochondrial Adaptation to Fasting but Not in Fatty Acid Oxidation or Fatty Acid Anion Export

(2008) Erin L. Seifert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Mechanism of Mitochondrial Superoxide Production by the Cytochromebc1Complex

(2008) Stefan Dröse et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Beneficial Effect of Coenzyme Q10 on Increased Oxidative and Nitrative Stress and Inflammation and Individual Metabolic Components Developing in a Rat Model of Metabolic Syndrome

(2008) Masaru Kunitomo et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Myocardial Steatosis Is an Independent Predictor of Diastolic Dysfunction in Type 2 Diabetes Mellitus

(2008) Luuk J. Rijzewijk et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Endocrine alterations in response to calorie restriction in humans

(2008) Leanne M. Redman et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Molecular and metabolic mechanisms of insulin resistance and β-cell failure in type 2 diabetes

(2008) Deborah M. Muoio et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Pharmacological and Clinical Aspects of Heme Oxygenase

(2008) N. G. Abraham et al.   PHARMACOLOGICAL REVIEWS

Renal mitochondrial impairment is attenuated by AT1 blockade in experimental Type I diabetes

(2007) Elena M. V. de Cavanagh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Astaxanthin protects mesangial cells from hyperglycemia-induced oxidative signaling

(2007) Emiko Manabe et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Oxidative stress induces GLUT4 translocation by activation of PI3-K/Akt and dual AMPK kinase in cardiac myocytes

(2007) Takahiro Horie et al.   JOURNAL OF CELLULAR PHYSIOLOGY

ΔΨm-Dependent and -independent production of reactive oxygen species by rat brain mitochondria

(2003) Tatyana V. Votyakova et al.   JOURNAL OF NEUROCHEMISTRY