Prevention of diabetic nephropathy in Ins2+/−AkitaJmice by the mitochondria-targeted therapy MitoQ

Inhibition of Connective Tissue Growth Factor Overexpression in Diabetic Retinopathy by SERPINA3K via Blocking the WNT/ -Catenin Pathway

(2010) B. Zhang et al.   DIABETES

The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C patients

(2010) Edward J. Gane et al.   LIVER INTERNATIONAL

A double-blind, placebo-controlled study to assess the mitochondria-targeted antioxidant MitoQ as a disease-modifying therapy in Parkinson's disease

(2010) Barry J. Snow et al.   MOVEMENT DISORDERS

Sulodexide ameliorates early but not late kidney disease in models of radiation nephropathy and diabetic nephropathy

(2010) M. Rossini et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Lack of both bradykinin B1 and B2 receptors enhances nephropathy, neuropathy, and bone mineral loss in Akita diabetic mice

(2010) M. Kakoki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity

(2010) F. Weinberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chronic COX Inhibition Reduces Diabetes-Induced Hyperfiltration, Proteinuria, and Renal Pathological Markers in 36-Week B6-Ins2Akita Mice

(2009) Rania Nasrallah et al.   AMERICAN JOURNAL OF NEPHROLOGY

Coenzyme Q deficiency triggers mitochondria degradation by mitophagy

(2009) Ángeles Rodríguez-Hernández et al.   Autophagy

Doxorubicin Inactivates Myocardial Cytochrome c Oxidase in Rats: Cardioprotection by Mito-Q

(2009) Karunakaran Chandran et al.   BIOPHYSICAL JOURNAL

Tissue-Specific Remodeling of the Mitochondrial Proteome in Type 1 Diabetic Akita Mice

(2009) H. Bugger et al.   DIABETES

Human Recombinant ACE2 Reduces the Progression of Diabetic Nephropathy

(2009) G. Y. Oudit et al.   DIABETES

Mitochondria-Targeted Antioxidant MitoQ 10 Improves Endothelial Function and Attenuates Cardiac Hypertrophy

(2009) Delyth Graham et al.   HYPERTENSION

Reduction of Renal Superoxide Dismutase in Progressive Diabetic Nephropathy

(2009) H. Fujita et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Dickkopf-1 Promotes Hyperglycemia-Induced Accumulation of Mesangial Matrix and Renal Dysfunction

(2009) C.-L. Lin et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Wnt/ -Catenin Signaling Promotes Renal Interstitial Fibrosis

(2009) W. He et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

RAGE-Induced Cytosolic ROS Promote Mitochondrial Superoxide Generation in Diabetes

(2009) M. T. Coughlan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Alteration of renal respiratory Complex-III during experimental type-1 diabetes

(2009) Shankar Munusamy et al.   BMC Endocrine Disorders

Type 1 Diabetic Akita Mouse Hearts Are Insulin Sensitive but Manifest Structurally Abnormal Mitochondria That Remain Coupled Despite Increased Uncoupling Protein 3

(2008) H. Bugger et al.   DIABETES

The mitochondria-targeted antioxidant MitoQ protects against organ damage in a lipopolysaccharide–peptidoglycan model of sepsis

(2008) Damon A. Lowes et al.   FREE RADICAL BIOLOGY AND MEDICINE

Comparison of methods for determination of glomerular filtration rate: low and high-dose Tc-99m-DTPA renography, predicted creatinine clearance method, and plasma sample method

(2008) Majid Assadi et al.   INTERNATIONAL UROLOGY AND NEPHROLOGY

Correlation of enhanced thrombospondin-1 expression, TGF-  signalling and proteinuria in human type-2 diabetic nephropathy

(2008) B. Hohenstein et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION