PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy
Published 2012 View Full Article
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Title
PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy
Authors
Keywords
-
Journal
Scientific Reports
Volume 2, Issue 1, Pages -
Publisher
Springer Nature
Online
2012-12-19
DOI
10.1038/srep01002
References
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Related references
Note: Only part of the references are listed.- Role of PINK1 Binding to the TOM Complex and Alternate Intracellular Membranes in Recruitment and Activation of the E3 Ligase Parkin
- (2012) Michael Lazarou et al. DEVELOPMENTAL CELL
- PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria
- (2012) Kei Okatsu et al. Nature Communications
- PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65
- (2012) C. Kondapalli et al. Open Biology
- Parkinson's Disease–Associated Kinase PINK1 Regulates Miro Protein Level and Axonal Transport of Mitochondria
- (2012) Song Liu et al. PLoS Genetics
- PINK1 and Parkin Target Miro for Phosphorylation and Degradation to Arrest Mitochondrial Motility
- (2011) Xinnan Wang et al. CELL
- Autoregulation of Parkin activity through its ubiquitin-like domain
- (2011) Viduth K Chaugule et al. EMBO JOURNAL
- Broad activation of the ubiquitin–proteasome system by Parkin is critical for mitophagy
- (2011) Nickie C. Chan et al. HUMAN MOLECULAR GENETICS
- Human proteome analysis by using reversed phase monolithic silica capillary columns with enhanced sensitivity
- (2011) Mio Iwasaki et al. JOURNAL OF CHROMATOGRAPHY A
- The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking
- (2011) Cathrin Meissner et al. JOURNAL OF NEUROCHEMISTRY
- Mutations in PINK1 and Parkin Impair Ubiquitination of Mitofusins in Human Fibroblasts
- (2011) Aleksandar Rakovic et al. PLoS One
- Discovery of catalytically active orthologues of the Parkinson's disease kinase PINK1: analysis of substrate specificity and impact of mutations
- (2011) H. I. Woodroof et al. Open Biology
- p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both
- (2010) Derek Narendra et al. Autophagy
- PINK1 is recruited to mitochondria with parkin and associates with LC3 in mitophagy
- (2010) Sumihiro Kawajiri et al. FEBS LETTERS
- Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy
- (2010) Matthew E. Gegg et al. HUMAN MOLECULAR GENETICS
- PINK1 cleavage at position A103 by the mitochondrial protease PARL
- (2010) Emma Deas et al. HUMAN MOLECULAR GENETICS
- Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
- (2010) Atsushi Tanaka et al. JOURNAL OF CELL BIOLOGY
- Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL
- (2010) Seok Min Jin et al. JOURNAL OF CELL BIOLOGY
- PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
- (2010) Noriyuki Matsuda et al. JOURNAL OF CELL BIOLOGY
- PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
- (2010) Sven Geisler et al. NATURE CELL BIOLOGY
- Drosophila Parkin requires PINK1 for mitochondrial translocation and ubiquitinates Mitofusin
- (2010) E. Ziviani et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
- (2010) Derek P. Narendra et al. PLOS BIOLOGY
- The Loss of PGAM5 Suppresses the Mitochondrial Degeneration Caused by Inactivation of PINK1 in Drosophila
- (2010) Yuzuru Imai et al. PLoS Genetics
- Parkin stabilizes PINK1 through direct interaction
- (2009) Kahori Shiba et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Phosphorylation of parkin by Parkinson disease-linked kinase PINK1 activates parkin E3 ligase function and NF- B signaling
- (2009) D. Sha et al. HUMAN MOLECULAR GENETICS
- PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
- (2009) C. Vives-Bauza et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PINK1 controls mitochondrial localization of Parkin through direct phosphorylation
- (2008) Yongsung Kim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson's disease factors Pink1 and Parkin
- (2008) A. J. Whitworth et al. Disease Models & Mechanisms
- Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
- (2008) Derek Narendra et al. JOURNAL OF CELL BIOLOGY
- The kinase domain of mitochondrial PINK1 faces the cytoplasm
- (2008) C. Zhou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cytoplasmic localization and proteasomal degradation of N-terminally cleaved form of PINK1
- (2007) Sho Takatori et al. NEUROSCIENCE LETTERS
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