- Home
- Publications
- Publication Search
- Publication Details
Title
Twenty Years of AIRE
Authors
Keywords
-
Journal
Frontiers in Immunology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2018-02-12
DOI
10.3389/fimmu.2018.00098
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Dominant-negative loss of function arises from a second, more frequent variant within the SAND domain of autoimmune regulator ( AIRE )
- (2018) Jordan K. Abbott et al. JOURNAL OF AUTOIMMUNITY
- Update on Aire and thymic negative selection
- (2017) Geraldo A. Passos et al. IMMUNOLOGY
- Central immune tolerance depends on crosstalk between the classical and alternative NF-κB pathways in medullary thymic epithelial cells
- (2017) Marc Riemann et al. JOURNAL OF AUTOIMMUNITY
- DNA breaks and chromatin structural changes enhance the transcription of autoimmune regulator target genes
- (2017) Mithu Guha et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Redefining thymus medulla specialization for central tolerance
- (2017) Emilie J. Cosway et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Mode of Tolerance Induction and Requirement for Aire Are Governed by the Cell Types That Express Self-Antigen and Those That Present Antigen
- (2017) Yasuhiro Mouri et al. JOURNAL OF IMMUNOLOGY
- AIRE is a critical spindle-associated protein in embryonic stem cells
- (2017) Bin Gu et al. eLife
- Relb acts downstream of medullary thymic epithelial stem cells and is essential for the emergence of RANK+ medullary epithelial progenitors
- (2016) Song Baik et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Dynamic spatio-temporal contribution of single β5t+ cortical epithelial precursors to the thymus medulla
- (2016) Carlos E. Mayer et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Aire Inhibits the Generation of a Perinatal Population of Interleukin-17A-Producing γδ T Cells to Promote Immunologic Tolerance
- (2016) Noriyuki Fujikado et al. IMMUNITY
- Aire Enforces Immune Tolerance by Directing Autoreactive T Cells into the Regulatory T Cell Lineage
- (2016) Sven Malchow et al. IMMUNITY
- Dendritic Cells Coordinate the Development and Homeostasis of Organ-Specific Regulatory T Cells
- (2016) Daniel S. Leventhal et al. IMMUNITY
- Development of T-cell tolerance utilizes both cell-autonomous and cooperative presentation of self-antigen
- (2016) Justin S. A. Perry et al. IMMUNOLOGICAL REVIEWS
- Autoimmune regulator and self-tolerance - molecular and clinical aspects
- (2016) Jakub Abramson et al. IMMUNOLOGICAL REVIEWS
- Estrogen-mediated downregulation of AIRE influences sexual dimorphism in autoimmune diseases
- (2016) Nadine Dragin et al. JOURNAL OF CLINICAL INVESTIGATION
- Identification of embryonic precursor cells that differentiate into thymic epithelial cells expressing autoimmune regulator
- (2016) Nobuko Akiyama et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Aire knockdown in medullary thymic epithelial cells affects Aire protein, deregulates cell adhesion genes and decreases thymocyte interaction
- (2016) Nicole Pezzi et al. MOLECULAR IMMUNOLOGY
- Roles of eukaryotic topoisomerases in transcription, replication and genomic stability
- (2016) Yves Pommier et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Sex bias in CNS autoimmune disease mediated by androgen control of autoimmune regulator
- (2016) Meng-Lei Zhu et al. Nature Communications
- Increased generation of Foxp3+ regulatory T cells by manipulating antigen presentation in the thymus
- (2016) Jiqiang Lin et al. Nature Communications
- Critical role of SP thymocyte motility in regulation of thymic output in neonatal Aire-/- mice
- (2016) Rong Jin et al. Oncotarget
- Identification of a Bipotent Epithelial Progenitor Population in the Adult Thymus
- (2016) Svetlana Ulyanchenko et al. Cell Reports
- A Thymic Epithelial Stem Cell Pool Persists throughout Ontogeny and Is Modulated by TGF-β
- (2016) Olga Ucar et al. Cell Reports
- Aire Downregulation Is Associated with Changes in the Posttranscriptional Control of Peripheral Tissue Antigens in Medullary Thymic Epithelial Cells
- (2016) Ernna H. Oliveira et al. Frontiers in Immunology
- Foxn1 Is Dynamically Regulated in Thymic Epithelial Cells during Embryogenesis and at the Onset of Thymic Involution
- (2016) Kathy E. O’Neill et al. PLoS One
- Central tolerance to self revealed by the autoimmune regulator
- (2015) Alice Y. Chan et al. Annals of the New York Academy of Sciences
- Impaired thymic expression of tissue-restricted antigens licenses the de novo generation of autoreactive CD4+ T cells in acute GVHD
- (2015) S. Dertschnig et al. BLOOD
- Alternative NF-κB signaling regulates mTEC differentiation from podoplanin-expressing precursors in the cortico-medullary junction
- (2015) Lucas Onder et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Thymus medulla fosters generation of natural Treg cells, invariant γδ T cells, and invariant NKT cells: What we learn from intrathymic migration
- (2015) Jennifer E. Cowan et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Thymic B Cells Are Licensed to Present Self Antigens for Central T Cell Tolerance Induction
- (2015) Tomoyoshi Yamano et al. IMMUNITY
- Dominant Mutations in the Autoimmune Regulator AIRE Are Associated with Common Organ-Specific Autoimmune Diseases
- (2015) Bergithe E. Oftedal et al. IMMUNITY
- Aire-dependent peripheral tissue antigen mRNAs in mTEC cells feature networking refractoriness to microRNA interaction
- (2015) Claudia Macedo et al. IMMUNOBIOLOGY
- Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens
- (2015) Gabriel Skogberg et al. IMMUNOLOGY AND CELL BIOLOGY
- PRKDC mutations associated with immunodeficiency, granuloma, and autoimmune regulator–dependent autoimmunity
- (2015) Anne-Laure Mathieu et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Natural Th17 cells are critically regulated by functional medullary thymic microenvironments
- (2015) William E. Jenkinson et al. JOURNAL OF AUTOIMMUNITY
- Differential Features of AIRE-Induced and AIRE-Independent Promiscuous Gene Expression in Thymic Epithelial Cells
- (2015) Charles St-Pierre et al. JOURNAL OF IMMUNOLOGY
- Ectopic Aire Expression in the Thymic Cortex Reveals Inherent Properties of Aire as a Tolerogenic Factor within the Medulla
- (2015) Hitoshi Nishijima et al. JOURNAL OF IMMUNOLOGY
- Osteoprotegerin-Mediated Homeostasis of Rank+Thymic Epithelial Cells Does Not Limit Foxp3+Regulatory T Cell Development
- (2015) Nicholas I. McCarthy et al. JOURNAL OF IMMUNOLOGY
- Aire Expression Is Inherent to Most Medullary Thymic Epithelial Cells during Their Differentiation Program
- (2015) H. Kawano et al. JOURNAL OF IMMUNOLOGY
- Sirt-ainly Aire
- (2015) Pärt Peterson NATURE IMMUNOLOGY
- Aire controls gene expression in the thymic epithelium with ordered stochasticity
- (2015) Matthew Meredith et al. NATURE IMMUNOLOGY
- The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of central immunological tolerance
- (2015) Anna Chuprin et al. NATURE IMMUNOLOGY
- Single-cell transcriptome analysis reveals coordinated ectopic gene-expression patterns in medullary thymic epithelial cells
- (2015) Philip Brennecke et al. NATURE IMMUNOLOGY
- Brd4 bridges the transcriptional regulators, Aire and P-TEFb, to promote elongation of peripheral-tissue antigen transcripts in thymic stromal cells
- (2015) Hideyuki Yoshida et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance
- (2015) S. Yang et al. SCIENCE
- Sex hormones have pervasive effects on thymic epithelial cells
- (2015) Maude Dumont-Lagacé et al. Scientific Reports
- Adult Thymic Medullary Epithelium Is Maintained and Regenerated by Lineage-Restricted Cells Rather Than Bipotent Progenitors
- (2015) Izumi Ohigashi et al. Cell Reports
- Thymic Crosstalk Coordinates Medulla Organization and T-Cell Tolerance Induction
- (2015) Noëlla Lopes et al. Frontiers in Immunology
- Promiscuous Gene Expression in the Thymus: A Matter of Epigenetics, miRNA, and More?
- (2015) Olga Ucar et al. Frontiers in Immunology
- The Thymic Orchestration Involving Aire, miRNAs, and Cell–Cell Interactions during the Induction of Central Tolerance
- (2015) Geraldo Aleixo Passos et al. Frontiers in Immunology
- Homeodomain-Interacting Protein Kinase 2, a Novel Autoimmune Regulator Interaction Partner, Modulates Promiscuous Gene Expression in Medullary Thymic Epithelial Cells
- (2015) Kristin Rattay et al. JOURNAL OF IMMUNOLOGY
- Promiscuous mRNA splicing under the control of AIRE in medullary thymic epithelial cells
- (2014) Peter Keane et al. BIOINFORMATICS
- Regeneration of the aged thymus by a single transcription factor
- (2014) N. Bredenkamp et al. DEVELOPMENT
- Intermediate expression of CCRL1 reveals novel subpopulations of medullary thymic epithelial cells that emerge in the postnatal thymus
- (2014) Ana R. Ribeiro et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Canonical microRNAs in thymic epithelial cells promote central tolerance
- (2014) Imran S. Khan et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The possible implication of the S250C variant of the autoimmune regulator protein in a patient with autoimmunity and immunodeficiency: in silico analysis suggests a molecular pathogenic mechanism for the variant
- (2014) Emanuele Bellacchio et al. GENE
- Population and single-cell genomics reveal theAiredependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia
- (2014) Stephen N. Sansom et al. GENOME RESEARCH
- Adult Thymus Contains FoxN1− Epithelial Stem Cells that Are Bipotent for Medullary and Cortical Thymic Epithelial Lineages
- (2014) Ahmet Ucar et al. IMMUNITY
- Distinct Contributions of Aire and Antigen-Presenting-Cell Subsets to the Generation of Self-Tolerance in the Thymus
- (2014) Justin S.A. Perry et al. IMMUNITY
- Dedicated mTEC Progenitors Stay True, Even into Adulthood
- (2014) Korosh Kianizad et al. IMMUNITY
- Limitation of immune tolerance–inducing thymic epithelial cell development by Spi-B–mediated negative feedback regulation
- (2014) Nobuko Akiyama et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The Lymphotoxin Pathway Regulates Aire-Independent Expression of Ectopic Genes and Chemokines in Thymic Stromal Cells
- (2014) N. Seach et al. JOURNAL OF IMMUNOLOGY
- Expression of Aire and the Early Wave of Apoptosis in Spermatogenesis
- (2014) C. E. Schaller et al. JOURNAL OF IMMUNOLOGY
- Alterations of the Medullary Epithelial Compartment in the Aire-Deficient Thymus: Implications for Programs of Thymic Epithelial Differentiation
- (2014) J. Dooley et al. JOURNAL OF IMMUNOLOGY
- Checkpoints in the Development of Thymic Cortical Epithelial Cells
- (2014) S. Shakib et al. JOURNAL OF IMMUNOLOGY
- Lt r Signaling Does Not Regulate Aire-Dependent Transcripts in Medullary Thymic Epithelial Cells
- (2014) V. C. Martins et al. JOURNAL OF IMMUNOLOGY
- Temporal Lineage Tracing of Aire-Expressing Cells Reveals a Requirement for Aire in Their Maturation Program
- (2014) Y. Nishikawa et al. JOURNAL OF IMMUNOLOGY
- NF-κB–Inducing Kinase in Thymic Stroma Establishes Central Tolerance by Orchestrating Cross-Talk with Not Only Thymocytes but Also Dendritic Cells
- (2014) Yasuhiro Mouri et al. JOURNAL OF IMMUNOLOGY
- An Essential Role for Medullary Thymic Epithelial Cells during the Intrathymic Development of Invariant NKT Cells
- (2014) A. J. White et al. JOURNAL OF IMMUNOLOGY
- The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance
- (2014) Michael Waterfield et al. NATURE IMMUNOLOGY
- Identification of Novel Thymic Epithelial Cell Subsets Whose Differentiation Is Regulated by RANKL and Traf6
- (2014) Nichole M. Danzl et al. PLoS One
- Long-Term Persistence of Functional Thymic Epithelial Progenitor Cells In Vivo under Conditions of Low FOXN1 Expression
- (2014) Xin Jin et al. PLoS One
- Three Distinct Subsets of Thymic Epithelial Cells in Rats and Mice Defined by Novel Antibodies
- (2014) Yasushi Sawanobori et al. PLoS One
- An RNAi screen for Aire cofactors reveals a role for Hnrnpl in polymerase release and Aire-activated ectopic transcription
- (2014) M. Giraud et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Multilineage Potential and Self-Renewal Define an Epithelial Progenitor Cell Population in the Adult Thymus
- (2014) Kahlia Wong et al. Cell Reports
- In vitro co-culture systems for studying molecular basis of cellular interaction between Aire-expressing medullary thymic epithelial cells and fresh thymocytes
- (2014) Y. Yamaguchi et al. Biology Open
- FOXN1GFP/w Reporter hESCs Enable Identification of Integrin-β4, HLA-DR, and EpCAM as Markers of Human PSC-Derived FOXN1+ Thymic Epithelial Progenitors
- (2014) Chew-Li Soh et al. Stem Cell Reports
- Lymphopenia-Induced Proliferation in Aire-Deficient Mice Helps to Explain Their Autoimmunity and Differences from Human Patients
- (2014) Kai Kisand et al. Frontiers in Immunology
- The biophysical and biochemical properties of the autoimmune regulator (AIRE) protein
- (2013) Roberto Perniola et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Epithelial cytoprotection sustains ectopic expression of tissue-restricted antigens in the thymus during murine acute GVHD
- (2013) S. Dertschnig et al. BLOOD
- Generation of Functional Thymic Epithelium from Human Embryonic Stem Cells that Supports Host T Cell Development
- (2013) Audrey V. Parent et al. Cell Stem Cell
- Directed Differentiation of Human Embryonic Stem Cells into Thymic Epithelial Progenitor-like Cells Reconstitutes the Thymic Microenvironment In Vivo
- (2013) Xiaoning Sun et al. Cell Stem Cell
- Maturation and Emigration of Single-Positive Thymocytes
- (2013) Xi Xu et al. Clinical & Developmental Immunology
- Generation of both cortical and Aire+medullary thymic epithelial compartments from CD205+progenitors
- (2013) Song Baik et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Serial progression of cortical and medullary thymic epithelial microenvironments
- (2013) Nuno L. Alves et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- An evolutionarily conserved mutual interdependence between Aire and microRNAs in promiscuous gene expression
- (2013) Olga Ucar et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Analysis of the autoimmune regulator gene in patients with autoimmune non-APECED polyendocrinopathies
- (2013) Alessia Palma et al. GENOMICS
- Extrathymic Aire-Expressing Cells Are a Distinct Bone Marrow-Derived Population that Induce Functional Inactivation of CD4+ T Cells
- (2013) James M. Gardner et al. IMMUNITY
- Redox balance of mouse medullary CD4 single-positive thymocytes
- (2013) Rong Jin et al. IMMUNOLOGY AND CELL BIOLOGY
- Medullary thymic epithelial cell depletion leads to autoimmune hepatitis
- (2013) Anthony J. Bonito et al. JOURNAL OF CLINICAL INVESTIGATION
- Inactivation of the RB family prevents thymus involution and promotes thymic function by direct control of Foxn1 expression
- (2013) Phillip M. Garfin et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Macroautophagy substrates are loaded onto MHC class II of medullary thymic epithelial cells for central tolerance
- (2013) Martin Aichinger et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Thymocyte Selection Regulates the Homeostasis of IL-7-Expressing Thymic Cortical Epithelial Cells In Vivo
- (2013) A. R. Ribeiro et al. JOURNAL OF IMMUNOLOGY
- Lymphotoxin Receptor Regulates the Development of CCL21-Expressing Subset of Postnatal Medullary Thymic Epithelial Cells
- (2013) E. Lkhagvasuren et al. JOURNAL OF IMMUNOLOGY
- Thymic Medullary Epithelium and Thymocyte Self-Tolerance Require Cooperation between CD28-CD80/86 and CD40-CD40L Costimulatory Pathways
- (2013) J. A. Williams et al. JOURNAL OF IMMUNOLOGY
- Homeostatic Properties and Phenotypic Maturation of Murine CD4+ Pre-Thymic Emigrants in the Thymus
- (2013) Jie Dong et al. PLoS One
- Autoimmune Gastro-Pancreatitis with Anti-Protein Disulfide Isomerase-Associated 2 Autoantibody in Aire-Deficient BALB/cAnN Mice
- (2013) Hironori Kurisaki et al. PLoS One
- Label Retention Identifies a Multipotent Mesenchymal Stem Cell-Like Population in the Postnatal Thymus
- (2013) Masako Osada et al. PLoS One
- TRAF3 enforces the requirement for T cell cross-talk in thymic medullary epithelial development
- (2013) S. R. Jenkinson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Overlapping gene coexpression patterns in human medullary thymic epithelial cells generate self-antigen diversity
- (2013) S. Pinto et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Aire's plant homeodomain(PHD)-2 is critical for induction of immunological tolerance
- (2013) S. Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Aire-expressing thymic medullary epithelial cells originate from 5t-expressing progenitor cells
- (2013) I. Ohigashi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells
- (2013) S. Malchow et al. SCIENCE
- BPIFB1 Is a Lung-Specific Autoantigen Associated with Interstitial Lung Disease
- (2013) A. K. Shum et al. Science Translational Medicine
- Transcriptome sequencing of neonatal thymic epithelial cells
- (2013) Charles St-Pierre et al. Scientific Reports
- Lineage Tracing and Cell Ablation Identify a Post-Aire-Expressing Thymic Epithelial Cell Population
- (2013) Todd C. Metzger et al. Cell Reports
- Which Model Better Fits the Role of Aire in the Establishment of Self-Tolerance: The Transcription Model or the Maturation Model?
- (2013) Mitsuru Matsumoto et al. Frontiers in Immunology
- The Many Faces of Aire in Central Tolerance
- (2013) Martti Laan et al. Frontiers in Immunology
- The Effect of Age on Thymic Function
- (2013) Donald B. Palmer Frontiers in Immunology
- Organ-specific regulatory T cells of thymic origin are expanded in murine prostate tumors
- (2013) Sven Malchow et al. OncoImmunology
- Essential roles of insulin expression in Aire+ tolerogenic dendritic cells in maintaining peripheral self-tolerance of islet β-cells
- (2012) Maria Grupillo et al. CELLULAR IMMUNOLOGY
- Expression of the Autoimmune Regulator Gene and Its Relevance to the Mechanisms of Central and Peripheral Tolerance
- (2012) Roberto Perniola Clinical & Developmental Immunology
- Aire mediates thymic expression and tolerance of pancreatic antigens via an unconventional transcriptional mechanism
- (2012) Dina Danso-Abeam et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Screening for novel lead compounds increasing insulin expression in medullary thymic epithelial cells
- (2012) Xiu-ying Yang et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Autoimmune regulator is acetylated by transcription coactivator CBP/p300
- (2012) Mario Saare et al. EXPERIMENTAL CELL RESEARCH
- Rank Signaling Links the Development of Invariant γδ T Cell Progenitors and Aire+ Medullary Epithelium
- (2012) Natalie A. Roberts et al. IMMUNITY
- Autoimmune regulator (Aire) controls the expression of microRNAs in medullary thymic epithelial cells
- (2012) Claudia Macedo et al. IMMUNOBIOLOGY
- Expression profile of peripheral tissue antigen genes in medullary thymic epithelial cells (mTECs) is dependent on mRNA levels of autoimmune regulator (Aire)
- (2012) Ernna H. Oliveira et al. IMMUNOBIOLOGY
- Purified enzymes improve isolation and characterization of the adult thymic epithelium
- (2012) Natalie Seach et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Three-Dimensional Visualization of the Mouse Thymus Organization in Health and Immunodeficiency
- (2012) M. Irla et al. JOURNAL OF IMMUNOLOGY
- An Organotypic Coculture Model Supporting Proliferation and Differentiation of Medullary Thymic Epithelial Cells and Promiscuous Gene Expression
- (2012) S. Pinto et al. JOURNAL OF IMMUNOLOGY
- MicroRNAs Control the Maintenance of Thymic Epithelia and Their Competence for T Lineage Commitment and Thymocyte Selection
- (2012) S. Zuklys et al. JOURNAL OF IMMUNOLOGY
- Defective Autoimmune Regulator-Dependent Central Tolerance to Myelin Protein Zero Is Linked to Autoimmune Peripheral Neuropathy
- (2012) M. A. Su et al. JOURNAL OF IMMUNOLOGY
- Developmentally Regulated Availability of RANKL and CD40 Ligand Reveals Distinct Mechanisms of Fetal and Adult Cross-Talk in the Thymus Medulla
- (2012) G. E. Desanti et al. JOURNAL OF IMMUNOLOGY
- Unusual timing of CD127 expression by mouse uterine natural killer cells
- (2012) Jianhong Zhang et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Unmodified Histone H3K4 and DNA-Dependent Protein Kinase Recruit Autoimmune Regulator to Target Genes
- (2012) K. Zumer et al. MOLECULAR AND CELLULAR BIOLOGY
- AIRE-PHD fingers are structural hubs to maintain the integrity of chromatin-associated interactome
- (2012) Massimiliano Gaetani et al. NUCLEIC ACIDS RESEARCH
- The Immune Response to Melanoma Is Limited by Thymic Selection of Self-Antigens
- (2012) Ulrike Träger et al. PLoS One
- Antigen Recognition By Autoreactive Cd4+ Thymocytes Drives Homeostasis Of The Thymic Medulla
- (2012) Magali Irla et al. PLoS One
- Detection of an autoreactive T-cell population within the polyclonal repertoire that undergoes distinct autoimmune regulator (Aire)-mediated selection
- (2012) R. T. Taniguchi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Aire Promotes the Self-Renewal of Embryonic Stem Cells Through Lin28
- (2012) Gu Bin et al. STEM CELLS AND DEVELOPMENT
- TNF receptor family signaling in the development and functions of medullary thymic epithelial cells
- (2012) Taishin Akiyama et al. Frontiers in Immunology
- Post-Aire Maturation of Thymic Medullary Epithelial Cells Involves Selective Expression of Keratinocyte-Specific Autoantigens
- (2012) Xiaoping Wang et al. Frontiers in Immunology
- Mouse embryonic stem cell-derived thymic epithelial cell progenitors enhance T-cell reconstitution after allogeneic bone marrow transplantation
- (2011) L. Lai et al. BLOOD
- Aire regulates the transfer of antigen from mTECs to dendritic cells for induction of thymic tolerance
- (2011) F.-X. Hubert et al. BLOOD
- Expression and function of the autoimmune regulator (Aire) gene in non-thymic tissue
- (2011) S. A. Eldershaw et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Mouse thymic epithelial cell lines expressing “Aire” and peripheral tissue-specific antigens reproduce in vitro negative selection of T cells
- (2011) Yoshitaka Yamaguchi et al. EXPERIMENTAL CELL RESEARCH
- Control of central and peripheral tolerance by Aire
- (2011) Todd C. Metzger et al. IMMUNOLOGICAL REVIEWS
- Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development
- (2011) Yu Lei et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Enhanced isolation of adult thymic epithelial cell subsets for multiparameter flow cytometry and gene expression analysis
- (2011) Bryce T. McLelland et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Lymphotoxin Signal Promotes Thymic Organogenesis by Eliciting RANK Expression in the Embryonic Thymic Stroma
- (2011) Y. Mouri et al. JOURNAL OF IMMUNOLOGY
- Resident B cells regulate thymic expression of myelin oligodendrocyte glycoprotein
- (2011) Eitan M. Akirav et al. JOURNAL OF NEUROIMMUNOLOGY
- The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-α receptor
- (2011) Aikaterini S Papadopoulou et al. NATURE IMMUNOLOGY
- Patient mutation in AIRE disrupts P-TEFb binding and target gene transcription
- (2011) Kristina Žumer et al. NUCLEIC ACIDS RESEARCH
- Autoimmune regulator (AIRE)-deficient CD8+CD28low regulatory T lymphocytes fail to control experimental colitis
- (2011) C. Pomie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Aire unleashes stalled RNA polymerase to induce ectopic gene expression in thymic epithelial cells
- (2011) M. Giraud et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Defective Central Tolerance in Aire-Deficient Mice is not Sufficient to Induce Symptomatic Autoimmunity During Lymphopenia-Induced T cell Proliferation
- (2011) E. Kekäläinen et al. SCANDINAVIAN JOURNAL OF IMMUNOLOGY
- Foxn1 Regulates Lineage Progression in Cortical and Medullary Thymic Epithelial Cells But Is Dispensable for Medullary Sublineage Divergence
- (2011) Craig S. Nowell et al. PLoS Genetics
- Models of Aire-Dependent Gene Regulation for Thymic Negative Selection
- (2011) Dina Danso-Abeam et al. Frontiers in Immunology
- Recent insights into the role and molecular mechanisms of the autoimmune regulator (AIRE) gene in autoimmunity
- (2010) Alessandra Fierabracci AUTOIMMUNITY REVIEWS
- Aire regulates the expression of differentiation-associated genes and self-renewal of embryonic stem cells
- (2010) Bin Gu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Aire's Partners in the Molecular Control of Immunological Tolerance
- (2010) Jakub Abramson et al. CELL
- Cytokine crosstalk for thymic medulla formation
- (2010) Takeshi Nitta et al. CURRENT OPINION IN IMMUNOLOGY
- Both Polymorphic Variable Number of Tandem Repeats and Autoimmune Regulator Modulate Differential Expression of Insulin in Human Thymic Epithelial Cells
- (2010) C. Q. Cai et al. DIABETES
- PHD finger of autoimmune regulator: An epigenetic link between the histone modifications and tissue-specific antigen expression in thymus
- (2010) Giovanna Musco et al. Epigenetics
- Missing links between histones and RNA Pol II arising from SAND?
- (2010) Cristel C. Carles et al. Epigenetics
- Transplantation of autoimmune regulator-encoding bone marrow cells delays the onset of experimental autoimmune encephalomyelitis
- (2010) Hyun-Ja Ko et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Contrasting models for the roles of Aire in the differentiation program of epithelial cells in the thymic medulla
- (2010) Mitsuru Matsumoto EUROPEAN JOURNAL OF IMMUNOLOGY
- Risk of autoimmune diabetes in APECED: association with short alleles of the 5′insulin VNTR
- (2010) J Paquette et al. GENES AND IMMUNITY
- Collagen induced arthritis (CIA) in mice features regulatory transcriptional network connecting major histocompatibility complex (MHC H2) with autoantigen genes in the thymus
- (2010) Paula B. Donate et al. IMMUNOBIOLOGY
- The role of Aire in clonal selection
- (2010) Ruth T Taniguchi et al. IMMUNOLOGY AND CELL BIOLOGY
- Differentiation of induced pluripotent stem cells to thymic epithelial cells by phenotype
- (2010) Yuta Inami et al. IMMUNOLOGY AND CELL BIOLOGY
- The susceptibility of Aire−/− mice to experimental myasthenia gravis involves alterations in regulatory T cells
- (2010) Revital Aricha et al. JOURNAL OF AUTOIMMUNITY
- Biphasic Aire expression in early embryos and in medullary thymic epithelial cells before end-stage terminal differentiation
- (2010) Yumiko Nishikawa et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Lymph node–resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation
- (2010) Jarish N. Cohen et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions
- (2010) Anne L. Fletcher et al. JOURNAL OF EXPERIMENTAL MEDICINE
- An Autoimmune Response to Odorant Binding Protein 1a Is Associated with Dry Eye in the Aire-Deficient Mouse
- (2010) J. J. DeVoss et al. JOURNAL OF IMMUNOLOGY
- Diversity of TCRs on Natural Foxp3+ T Cells in Mice Lacking Aire Expression
- (2010) D. Daniely et al. JOURNAL OF IMMUNOLOGY
- Lymphotoxin Signals from Positively Selected Thymocytes Regulate the Terminal Differentiation of Medullary Thymic Epithelial Cells
- (2010) A. J. White et al. JOURNAL OF IMMUNOLOGY
- Morphogenesis and maintenance of the 3D thymic medulla and prevention of nude skin phenotype require FoxN1 in pre- and post-natal K14 epithelium
- (2010) Jianfei Guo et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Increased Apoptosis after Autoimmune Regulator Expression in Epithelial Cells Revealed by a Combined Quantitative Proteomics Approach
- (2010) Nuria Colomé et al. JOURNAL OF PROTEOME RESEARCH
- Age-related deregulation of Aire and peripheral tissue antigen genes in the thymic stroma of non-obese diabetic (NOD) mice is associated with autoimmune type 1 diabetes mellitus (DM-1)
- (2010) Thaís A. Fornari et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Autonomous role of medullary thymic epithelial cells in central CD4+ T cell tolerance
- (2010) Maria Hinterberger et al. NATURE IMMUNOLOGY
- The role of AIRE in human autoimmune disease
- (2010) Eitan M. Akirav et al. Nature Reviews Endocrinology
- Epigenetic regulation of promiscuous gene expression in thymic medullary epithelial cells
- (2010) L.-O. Tykocinski et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Global relevance of Aire binding to hypomethylated lysine-4 of histone-3
- (2010) A. S. Koh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- T-cell regulation by casitas B-lineage lymphoma (Cblb) is a critical failsafe against autoimmune disease due to autoimmune regulator (Aire) deficiency
- (2010) C. E. Teh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Differentiation of Pharyngeal Endoderm from Mouse Embryonic Stem Cell
- (2010) Kyoko Hidaka et al. STEM CELLS AND DEVELOPMENT
- Aire
- (2009) Diane Mathis et al. Annual Review of Immunology
- Short-term inhibition of p53 combined with keratinocyte growth factor improves thymic epithelial cell recovery and enhances T-cell reconstitution after murine bone marrow transplantation
- (2009) R. M. Kelly et al. BLOOD
- γδ T cells develop independently of Aire
- (2009) Heli Tuovinen et al. CELLULAR IMMUNOLOGY
- Thymus-specific deletion of insulin induces autoimmune diabetes
- (2009) Yong Fan et al. EMBO JOURNAL
- Studies in Mice Deficient for the Autoimmune Regulator (Aire) and Transgenic for the Thyrotropin Receptor Reveal a Role for Aire in Tolerance for Thyroid Autoantigens
- (2009) Alexander V. Misharin et al. ENDOCRINOLOGY
- Clearing the AIRE: On the Pathophysiological Basis of the Autoimmune Polyendocrinopathy Syndrome Type-1
- (2009) Noriko Shikama et al. ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA
- WhyAire? Compensating for late bloomers
- (2009) Melvin Cohn EUROPEAN JOURNAL OF IMMUNOLOGY
- Metallophilic macrophages are fully developed in the thymus of autoimmune regulator (Aire)-deficient mice
- (2009) Novica M. Milićević et al. HISTOCHEMISTRY AND CELL BIOLOGY
- AIRE activated tissue specific genes have histone modifications associated with inactive chromatin
- (2009) Tõnis Org et al. HUMAN MOLECULAR GENETICS
- Ultrastructure of medullary thymic epithelial cells of autoimmune regulator (Aire)-deficient mice
- (2009) Živana Milićević et al. IMMUNOLOGY AND CELL BIOLOGY
- AIRE deficiency leads to impaired iNKT cell development
- (2009) Emma Lindh et al. JOURNAL OF AUTOIMMUNITY
- An aberrant prostate antigen–specific immune response causes prostatitis in mice and is associated with chronic prostatitis in humans
- (2009) Yafei Hou et al. JOURNAL OF CLINICAL INVESTIGATION
- The thymic medulla: a unique microenvironment for intercellular self-antigen transfer
- (2009) Christian Koble et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Neonatal tolerance revisited: a perinatal window for Aire control of autoimmunity
- (2009) Mireia Guerau-de-Arellano et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Reduced Thymic Aire Expression and Abnormal NF- B2 Signaling in a Model of Systemic Autoimmunity
- (2009) A. L. Fletcher et al. JOURNAL OF IMMUNOLOGY
- Lessons from Thymic Epithelial Heterogeneity: FoxN1 and Tissue-Restricted Gene Expression by Extrathymic, Endodermally Derived Epithelium
- (2009) J. Dooley et al. JOURNAL OF IMMUNOLOGY
- Ablation and Regeneration of Tolerance-Inducing Medullary Thymic Epithelial Cells after Cyclosporine, Cyclophosphamide, and Dexamethasone Treatment
- (2009) A. L. Fletcher et al. JOURNAL OF IMMUNOLOGY
- Aire-Deficient C57BL/6 Mice Mimicking the Common Human 13-Base Pair Deletion Mutation Present with Only a Mild Autoimmune Phenotype
- (2009) F.-X. Hubert et al. JOURNAL OF IMMUNOLOGY
- Autoimmune Regulator Deficiency Results in Decreased Expression of CCR4 and CCR7 Ligands and in Delayed Migration of CD4+ Thymocytes
- (2009) M. Laan et al. JOURNAL OF IMMUNOLOGY
- Evidence for a network transcriptional control of promiscuous gene expression in medullary thymic epithelial cells
- (2009) Cláudia Macedo et al. MOLECULAR IMMUNOLOGY
- Thymic cysts originate from Foxn1 positive thymic medullary epithelium
- (2009) Eric Vroegindeweij et al. MOLECULAR IMMUNOLOGY
- The solution structure of the first PHD finger of autoimmune regulator in complex with non-modified histone H3 tail reveals the antagonistic role of H3R2 methylation
- (2009) Francesca Chignola et al. NUCLEIC ACIDS RESEARCH
- Regulatory T cell differentiation of thymocytes does not require a dedicated antigen-presenting cell but is under T cell-intrinsic developmental control
- (2009) G. Wirnsberger et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of an Autoantigen Demonstrates a Link Between Interstitial Lung Disease and a Defect in Central Tolerance
- (2009) A. K. Shum et al. Science Translational Medicine
- Generation of Thymic Epithelial Cell Progenitors by Mouse Embryonic Stem Cells
- (2009) Laijun Lai et al. STEM CELLS
- Structure and Site-Specific Recognition of Histone H3 by the PHD Finger of Human Autoimmune Regulator
- (2009) Suvobrata Chakravarty et al. STRUCTURE
- Control of central self-tolerance induction by autoreactive CD4+ thymocytes
- (2009) Magali Irla et al. TRENDS IN IMMUNOLOGY
- Overexpression of Lymphotoxin in T Cells Induces Fulminant Thymic Involution
- (2008) Mathias Heikenwalder et al. AMERICAN JOURNAL OF PATHOLOGY
- Keratinocyte growth factor and androgen blockade work in concert to protect against conditioning regimen-induced thymic epithelial damage and enhance T-cell reconstitution after murine bone marrow transplantation
- (2008) R. M. Kelly et al. BLOOD
- The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression
- (2008) Tõnis Org et al. EMBO REPORTS
- NKT cell development in the absence of the autoimmune regulator gene (Aire)
- (2008) Lauren A. Pitt et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Sequential phases in the development of Aire-expressing medullary thymic epithelial cells involve distinct cellular input
- (2008) Andrea J. White et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The Cytokine RANKL Produced by Positively Selected Thymocytes Fosters Medullary Thymic Epithelial Cells that Express Autoimmune Regulator
- (2008) Yu Hikosaka et al. IMMUNITY
- Autoantigen-Specific Interactions with CD4+ Thymocytes Control Mature Medullary Thymic Epithelial Cell Cellularity
- (2008) Magali Irla et al. IMMUNITY
- The Tumor Necrosis Factor Family Receptors RANK and CD40 Cooperatively Establish the Thymic Medullary Microenvironment and Self-Tolerance
- (2008) Taishin Akiyama et al. IMMUNITY
- Evolutionarily conserved and divergent regions of the Autoimmune Regulator (Aire) gene: a comparative analysis
- (2008) Mark Saltis et al. IMMUNOGENETICS
- Autoimmune Regulator Initiates the Expression of Promiscuous Genes in Thymic Epithelial Cells
- (2008) Jibing Chen et al. IMMUNOLOGICAL INVESTIGATIONS
- Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire
- (2008) Maureen A. Su et al. JOURNAL OF CLINICAL INVESTIGATION
- Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance
- (2008) Masashi Yano et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Transcriptional impact of Aire varies with cell type
- (2008) M. Guerau-de-Arellano et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The variable immunological self: Genetic variation and nongenetic noise in Aire-regulated transcription
- (2008) E. S. Venanzi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ectopic expression of peripheral-tissue antigens in the thymic epithelium: Probabilistic, monoallelic, misinitiated
- (2008) J. Villasenor et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity
- (2008) A. S. Koh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Promiscuous gene expression patterns in single medullary thymic epithelial cells argue for a stochastic mechanism
- (2008) J. Derbinski et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Deletional Tolerance Mediated by Extrathymic Aire-Expressing Cells
- (2008) J. M. Gardner et al. SCIENCE
- High Prevalence of Thyroid Autoimmunity in Apulian Patients with Autoimmune Polyglandular Syndrome Type 1
- (2008) Roberto Perniola et al. THYROID
- Death in the AIRE
- (2008) Brian J. Ferguson et al. TRENDS IN IMMUNOLOGY
- DNA-PK contributes to the phosphorylation of AIRE: Importance in transcriptional activity
- (2007) Ingrid Liiv et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Unbiased analysis, enrichment and purification of thymic stromal cells
- (2007) Daniel H.D. Gray et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Role of PHD fingers and COOH-terminal 30 amino acids in AIRE transactivation activity
- (2007) Alessandra Meloni et al. MOLECULAR IMMUNOLOGY
- Modulation of Aire regulates the expression of tissue-restricted antigens
- (2007) Vivian Kont et al. MOLECULAR IMMUNOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search