Thymic Crosstalk Coordinates Medulla Organization and T-Cell Tolerance Induction
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Thymic Crosstalk Coordinates Medulla Organization and T-Cell Tolerance Induction
Authors
Keywords
-
Journal
Frontiers in Immunology
Volume 6, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2015-07-20
DOI
10.3389/fimmu.2015.00365
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Thymic B Cells Are Licensed to Present Self Antigens for Central T Cell Tolerance Induction
- (2015) Tomoyoshi Yamano et al. IMMUNITY
- Human thymic epithelial primary cells produce exosomes carrying tissue-restricted antigens
- (2015) Gabriel Skogberg et al. IMMUNOLOGY AND CELL BIOLOGY
- For3D: Full organ reconstruction in 3D, an automatized tool for deciphering the complexity of lymphoid organs
- (2015) Arnauld Sergé et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Peripheral regulatory T lymphocytes recirculating to the thymus suppress the development of their precursors
- (2015) Nicolas Thiault et al. NATURE IMMUNOLOGY
- Population and single-cell genomics reveal theAiredependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia
- (2014) Stephen N. Sansom et al. GENOME RESEARCH
- Adult Thymus Contains FoxN1− Epithelial Stem Cells that Are Bipotent for Medullary and Cortical Thymic Epithelial Lineages
- (2014) Ahmet Ucar et al. IMMUNITY
- Distinct Contributions of Aire and Antigen-Presenting-Cell Subsets to the Generation of Self-Tolerance in the Thymus
- (2014) Justin S.A. Perry et al. IMMUNITY
- Medullary Thymic Epithelial Stem Cells Maintain a Functional Thymus to Ensure Lifelong Central T Cell Tolerance
- (2014) Miho Sekai et al. IMMUNITY
- Thymic CCL2 influences induction of T-cell tolerance
- (2014) O. Cédile et al. JOURNAL OF AUTOIMMUNITY
- Limitation of immune tolerance–inducing thymic epithelial cell development by Spi-B–mediated negative feedback regulation
- (2014) Nobuko Akiyama et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The Lymphotoxin Pathway Regulates Aire-Independent Expression of Ectopic Genes and Chemokines in Thymic Stromal Cells
- (2014) N. Seach et al. JOURNAL OF IMMUNOLOGY
- A Role for Intrathymic B Cells in the Generation of Natural Regulatory T Cells
- (2014) S. N. Walters et al. JOURNAL OF IMMUNOLOGY
- NF-κB–Inducing Kinase in Thymic Stroma Establishes Central Tolerance by Orchestrating Cross-Talk with Not Only Thymocytes but Also Dendritic Cells
- (2014) Yasuhiro Mouri et al. JOURNAL OF IMMUNOLOGY
- An Essential Role for Medullary Thymic Epithelial Cells during the Intrathymic Development of Invariant NKT Cells
- (2014) A. J. White et al. JOURNAL OF IMMUNOLOGY
- A regulatory role for TGF-β signaling in the establishment and function of the thymic medulla
- (2014) Mathias Hauri-Hohl et al. NATURE IMMUNOLOGY
- Multilineage Potential and Self-Renewal Define an Epithelial Progenitor Cell Population in the Adult Thymus
- (2014) Kahlia Wong et al. Cell Reports
- Generation of both cortical and Aire+medullary thymic epithelial compartments from CD205+progenitors
- (2013) Song Baik et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The thymic medulla is required for Foxp3+regulatory but not conventional CD4+thymocyte development
- (2013) Jennifer E. Cowan et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Macroautophagy substrates are loaded onto MHC class II of medullary thymic epithelial cells for central tolerance
- (2013) Martin Aichinger et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Thymocyte Selection Regulates the Homeostasis of IL-7-Expressing Thymic Cortical Epithelial Cells In Vivo
- (2013) A. R. Ribeiro et al. JOURNAL OF IMMUNOLOGY
- The Mechanism of Tissue-Restricted Antigen Gene Expression by AIRE
- (2013) K. Zumer et al. JOURNAL OF IMMUNOLOGY
- Thymic Medullary Epithelium and Thymocyte Self-Tolerance Require Cooperation between CD28-CD80/86 and CD40-CD40L Costimulatory Pathways
- (2013) J. A. Williams et al. JOURNAL OF IMMUNOLOGY
- Analysis of APC Types Involved in CD4 Tolerance and Regulatory T Cell Generation Using Reaggregated Thymic Organ Cultures
- (2013) L. Guerri et al. JOURNAL OF IMMUNOLOGY
- Murine thymic selection quantified using a unique method to capture deleted T cells
- (2013) G. L. Stritesky et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Aire-expressing thymic medullary epithelial cells originate from 5t-expressing progenitor cells
- (2013) I. Ohigashi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Autoreactive thymic B cells are efficient antigen-presenting cells of cognate self-antigens for T cell negative selection
- (2013) J. Perera et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells
- (2013) S. Malchow et al. SCIENCE
- Lineage Tracing and Cell Ablation Identify a Post-Aire-Expressing Thymic Epithelial Cell Population
- (2013) Todd C. Metzger et al. Cell Reports
- Regulations of Gene Expression in Medullary Thymic Epithelial Cells Required for Preventing the Onset of Autoimmune Diseases
- (2013) Taishin Akiyama et al. Frontiers in Immunology
- Plasmacytoid Dendritic Cells Transport Peripheral Antigens to the Thymus to Promote Central Tolerance
- (2012) Husein Hadeiba et al. IMMUNITY
- Rank Signaling Links the Development of Invariant γδ T Cell Progenitors and Aire+ Medullary Epithelium
- (2012) Natalie A. Roberts et al. IMMUNITY
- Three-Dimensional Visualization of the Mouse Thymus Organization in Health and Immunodeficiency
- (2012) M. Irla et al. JOURNAL OF IMMUNOLOGY
- Developmentally Regulated Availability of RANKL and CD40 Ligand Reveals Distinct Mechanisms of Fetal and Adult Cross-Talk in the Thymus Medulla
- (2012) G. E. Desanti et al. JOURNAL OF IMMUNOLOGY
- Antigen Recognition By Autoreactive Cd4+ Thymocytes Drives Homeostasis Of The Thymic Medulla
- (2012) Magali Irla et al. PLoS One
- Post-Aire Maturation of Thymic Medullary Epithelial Cells Involves Selective Expression of Keratinocyte-Specific Autoantigens
- (2012) Xiaoping Wang et al. Frontiers in Immunology
- Aire regulates the transfer of antigen from mTECs to dendritic cells for induction of thymic tolerance
- (2011) F.-X. Hubert et al. BLOOD
- Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development
- (2011) Yu Lei et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Lymphotoxin Signal Promotes Thymic Organogenesis by Eliciting RANK Expression in the Embryonic Thymic Stroma
- (2011) Y. Mouri et al. JOURNAL OF IMMUNOLOGY
- Autonomous versus dendritic cell-dependent contributions of medullary thymic epithelial cells to central tolerance
- (2011) Ludger Klein et al. TRENDS IN IMMUNOLOGY
- Plasmacytoid dendritic cells resident in human thymus drive natural Treg cell development
- (2010) E. Martin-Gayo et al. BLOOD
- How thymic antigen presenting cells sample the body's self-antigens
- (2010) Jens Derbinski et al. CURRENT OPINION IN IMMUNOLOGY
- Biphasic Aire expression in early embryos and in medullary thymic epithelial cells before end-stage terminal differentiation
- (2010) Yumiko Nishikawa et al. JOURNAL OF EXPERIMENTAL MEDICINE
- MHC class II–restricted antigen presentation by plasmacytoid dendritic cells inhibits T cell–mediated autoimmunity
- (2010) Magali Irla et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Thymic Stromal Lymphopoietin-Activated Plasmacytoid Dendritic Cells Induce the Generation of FOXP3+ Regulatory T Cells in Human Thymus
- (2010) S. Hanabuchi et al. JOURNAL OF IMMUNOLOGY
- Lymphotoxin Signals from Positively Selected Thymocytes Regulate the Terminal Differentiation of Medullary Thymic Epithelial Cells
- (2010) A. J. White et al. JOURNAL OF IMMUNOLOGY
- Autonomous role of medullary thymic epithelial cells in central CD4+ T cell tolerance
- (2010) Maria Hinterberger et al. NATURE IMMUNOLOGY
- B Cells Participate in Thymic Negative Selection of Murine Auto-reactive CD4+ T Cells
- (2010) Friederike Frommer et al. PLoS One
- CCR7 and CCR9 together recruit hematopoietic progenitors to the adult thymus
- (2009) D. A. Zlotoff et al. BLOOD
- CC chemokine receptor 7 and 9 double-deficient hematopoietic progenitors are severely impaired in seeding the adult thymus
- (2009) A. Krueger et al. BLOOD
- The thymic medulla: a unique microenvironment for intercellular self-antigen transfer
- (2009) Christian Koble et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Thymus-homing peripheral dendritic cells constitute two of the three major subsets of dendritic cells in the steady-state thymus
- (2009) JiChu Li et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Neonatal tolerance revisited: a perinatal window for Aire control of autoimmunity
- (2009) Mireia Guerau-de-Arellano et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Crucial Contribution of Thymic Sirp + Conventional Dendritic Cells to Central Tolerance against Blood-Borne Antigens in a CCR2-Dependent Manner
- (2009) T. Baba et al. JOURNAL OF IMMUNOLOGY
- The impact of negative selection on thymocyte migration in the medulla
- (2009) Marie Le Borgne et al. NATURE IMMUNOLOGY
- CCR7-mediated migration of developing thymocytes to the medulla is essential for negative selection to tissue-restricted antigens
- (2009) T. Nitta et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Control of central self-tolerance induction by autoreactive CD4+ thymocytes
- (2009) Magali Irla et al. TRENDS IN IMMUNOLOGY
- Intercellular MHC transfer between thymic epithelial and dendritic cells
- (2008) Virginie Millet et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Sequential phases in the development of Aire-expressing medullary thymic epithelial cells involve distinct cellular input
- (2008) Andrea J. White et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Antigen-Presentation Properties of Plasmacytoid Dendritic Cells
- (2008) José A. Villadangos et al. IMMUNITY
- The Cytokine RANKL Produced by Positively Selected Thymocytes Fosters Medullary Thymic Epithelial Cells that Express Autoimmune Regulator
- (2008) Yu Hikosaka et al. IMMUNITY
- Autoantigen-Specific Interactions with CD4+ Thymocytes Control Mature Medullary Thymic Epithelial Cell Cellularity
- (2008) Magali Irla et al. IMMUNITY
- The Tumor Necrosis Factor Family Receptors RANK and CD40 Cooperatively Establish the Thymic Medullary Microenvironment and Self-Tolerance
- (2008) Taishin Akiyama et al. IMMUNITY
- The impact of circulating dendritic cells on the development and differentiation of thymocytes
- (2008) Anna I Proietto et al. IMMUNOLOGY AND CELL BIOLOGY
- Clonal deletion of thymocytes can occur in the cortex with no involvement of the medulla
- (2008) Tom M. McCaughtry et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance
- (2008) Masashi Yano et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance
- (2008) Jelena Nedjic et al. NATURE
- CCR9 expression defines tolerogenic plasmacytoid dendritic cells able to suppress acute graft-versus-host disease
- (2008) Husein Hadeiba et al. NATURE IMMUNOLOGY
- Dendritic cells in the thymus contribute to T-regulatory cell induction
- (2008) A. I. Proietto et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulatory T Cells: Mechanisms of Differentiation and Function
- (2007) Steven Z. Josefowicz et al. Annual Review of Immunology
- Unbiased analysis, enrichment and purification of thymic stromal cells
- (2007) Daniel H.D. Gray et al. JOURNAL OF IMMUNOLOGICAL METHODS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More