An evolutionarily conserved mutual interdependence between Aire and microRNAs in promiscuous gene expression

Maintenance of Thymic Epithelial Phenotype Requires Extrinsic Signals in Mouse and Zebrafish

(2014) C. Soza-Ried et al.   JOURNAL OF IMMUNOLOGY

Lt r Signaling Does Not Regulate Aire-Dependent Transcripts in Medullary Thymic Epithelial Cells

(2014) V. C. Martins et al.   JOURNAL OF IMMUNOLOGY

MicroRNAs and autoimmunity

(2012) Angela Ceribelli et al.   CURRENT OPINION IN IMMUNOLOGY

Autoimmune regulator (Aire) controls the expression of microRNAs in medullary thymic epithelial cells

(2012) Claudia Macedo et al.   IMMUNOBIOLOGY

An Organotypic Coculture Model Supporting Proliferation and Differentiation of Medullary Thymic Epithelial Cells and Promiscuous Gene Expression

(2012) S. Pinto et al.   JOURNAL OF IMMUNOLOGY

MicroRNAs Control the Maintenance of Thymic Epithelia and Their Competence for T Lineage Commitment and Thymocyte Selection

(2012) S. Zuklys et al.   JOURNAL OF IMMUNOLOGY

Impaired thymic tolerance to α-myosin directs autoimmunity to the heart in mice and humans

(2011) HuiJuan Lv et al.   JOURNAL OF CLINICAL INVESTIGATION

Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development

(2011) Yu Lei et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-α receptor

(2011) Aikaterini S Papadopoulou et al.   NATURE IMMUNOLOGY

Aire unleashes stalled RNA polymerase to induce ectopic gene expression in thymic epithelial cells

(2011) M. Giraud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aire's Partners in the Molecular Control of Immunological Tolerance

(2010) Jakub Abramson et al.   CELL

Contrasting models for the roles of Aire in the differentiation program of epithelial cells in the thymic medulla

(2010) Mitsuru Matsumoto   EUROPEAN JOURNAL OF IMMUNOLOGY

Epigenetic regulation of promiscuous gene expression in thymic medullary epithelial cells

(2010) L.-O. Tykocinski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Thymus Medulla Slowly Yields Its Secrets

(2009) Lars-Oliver Tykocinski et al.   Annals of the New York Academy of Sciences

Aire

(2009) Diane Mathis et al.   Annual Review of Immunology

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Dicer Ablation Affects Antibody Diversity and Cell Survival in the B Lymphocyte Lineage

(2008) Sergei B. Koralov et al.   CELL

The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression

(2008) Tõnis Org et al.   EMBO REPORTS

Dicer-dependent microRNA pathway safeguards regulatory T cell function

(2008) Adrian Liston et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A skin microRNA promotes differentiation by repressing ‘stemness’

(2008) Rui Yi et al.   NATURE

Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes

(2008) Changchun Xiao et al.   NATURE IMMUNOLOGY

Small non-coding RNAs in animal development

(2008) Giovanni Stefani et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Transcriptional impact of Aire varies with cell type

(2008) M. Guerau-de-Arellano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity

(2008) A. S. Koh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deletional Tolerance Mediated by Extrathymic Aire-Expressing Cells

(2008) J. M. Gardner et al.   SCIENCE