The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of central immunological tolerance
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Title
The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of central immunological tolerance
Authors
Keywords
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Journal
NATURE IMMUNOLOGY
Volume 16, Issue 7, Pages 737-745
Publisher
Springer Nature
Online
2015-05-26
DOI
10.1038/ni.3194
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Related references
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- Aire unleashes stalled RNA polymerase to induce ectopic gene expression in thymic epithelial cells
- (2011) M. Giraud et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- Autoimmune Polyendocrine Syndromes: Clues to Type 1 Diabetes Pathogenesis
- (2010) Eystein S. Husebye et al. IMMUNITY
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- SIRT1-dependent regulation of chromatin and transcription: Linking NAD+ metabolism and signaling to the control of cellular functions
- (2009) Tong Zhang et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- AIRE activated tissue specific genes have histone modifications associated with inactive chromatin
- (2009) Tõnis Org et al. HUMAN MOLECULAR GENETICS
- The type III histone deacetylase Sirt1 is essential for maintenance of T cell tolerance in mice
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- The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression
- (2008) Tõnis Org et al. EMBO REPORTS
- sirt1-null mice develop an autoimmune-like condition
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- (2008) A. S. Koh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Deletional Tolerance Mediated by Extrathymic Aire-Expressing Cells
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- DNA-PK contributes to the phosphorylation of AIRE: Importance in transcriptional activity
- (2007) Ingrid Liiv et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
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