Control of central and peripheral tolerance by Aire

Effector Mechanisms of the Autoimmune Syndrome in the Murine Model of Autoimmune Polyglandular Syndrome Type 1

(2014) J. J. DeVoss et al.   JOURNAL OF IMMUNOLOGY

A Specific Anti-Aire Antibody Reveals Aire Expression Is Restricted to Medullary Thymic Epithelial Cells and Not Expressed in Periphery

(2014) F.-X. Hubert et al.   JOURNAL OF IMMUNOLOGY

Human Peripheral Lymphoid Tissues Contain Autoimmune Regulator-Expressing Dendritic Cells

(2010) Pietro Luigi Poliani et al.   AMERICAN JOURNAL OF PATHOLOGY

Clues to immune tolerance: the monogenic autoimmune syndromes

(2010) Michael Waterfield et al.   Annals of the New York Academy of Sciences

Aire's Partners in the Molecular Control of Immunological Tolerance

(2010) Jakub Abramson et al.   CELL

PHD finger of autoimmune regulator: An epigenetic link between the histone modifications and tissue-specific antigen expression in thymus

(2010) Giovanna Musco et al.   Epigenetics

Regulatory T cell defect in APECED patients is associated with loss of naive FOXP3+ precursors and impaired activated population

(2010) Sini M. Laakso et al.   JOURNAL OF AUTOIMMUNITY

Biphasic Aire expression in early embryos and in medullary thymic epithelial cells before end-stage terminal differentiation

(2010) Yumiko Nishikawa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regulation of medullary thymic epithelial cell differentiation and function by the signaling protein Sin

(2010) Nichole M. Danzl et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lymph node–resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation

(2010) Jarish N. Cohen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions

(2010) Anne L. Fletcher et al.   JOURNAL OF EXPERIMENTAL MEDICINE

An Autoimmune Response to Odorant Binding Protein 1a Is Associated with Dry Eye in the Aire-Deficient Mouse

(2010) J. J. DeVoss et al.   JOURNAL OF IMMUNOLOGY

Diversity of TCRs on Natural Foxp3+ T Cells in Mice Lacking Aire Expression

(2010) D. Daniely et al.   JOURNAL OF IMMUNOLOGY

Lymphotoxin Signals from Positively Selected Thymocytes Regulate the Terminal Differentiation of Medullary Thymic Epithelial Cells

(2010) A. J. White et al.   JOURNAL OF IMMUNOLOGY

Autonomous role of medullary thymic epithelial cells in central CD4+ T cell tolerance

(2010) Maria Hinterberger et al.   NATURE IMMUNOLOGY

Global relevance of Aire binding to hypomethylated lysine-4 of histone-3

(2010) A. S. Koh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aire

(2009) Diane Mathis et al.   Annual Review of Immunology

A hypomorphic allele of ZAP-70 reveals a distinct thymic threshold for autoimmune disease versus autoimmune reactivity

(2009) Lih-Yun Hsu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The thymic medulla: a unique microenvironment for intercellular self-antigen transfer

(2009) Christian Koble et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neonatal tolerance revisited: a perinatal window for Aire control of autoimmunity

(2009) Mireia Guerau-de-Arellano et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Ablation and Regeneration of Tolerance-Inducing Medullary Thymic Epithelial Cells after Cyclosporine, Cyclophosphamide, and Dexamethasone Treatment

(2009) A. L. Fletcher et al.   JOURNAL OF IMMUNOLOGY

Regulatory T cells exert checks and balances on self tolerance and autoimmunity

(2009) Kajsa Wing et al.   NATURE IMMUNOLOGY

Deaf1 isoforms control the expression of genes encoding peripheral tissue antigens in the pancreatic lymph nodes during type 1 diabetes

(2009) Linda Yip et al.   NATURE IMMUNOLOGY

The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression

(2008) Tõnis Org et al.   EMBO REPORTS

The Cytokine RANKL Produced by Positively Selected Thymocytes Fosters Medullary Thymic Epithelial Cells that Express Autoimmune Regulator

(2008) Yu Hikosaka et al.   IMMUNITY

Autoantigen-Specific Interactions with CD4+ Thymocytes Control Mature Medullary Thymic Epithelial Cell Cellularity

(2008) Magali Irla et al.   IMMUNITY

The Tumor Necrosis Factor Family Receptors RANK and CD40 Cooperatively Establish the Thymic Medullary Microenvironment and Self-Tolerance

(2008) Taishin Akiyama et al.   IMMUNITY

Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire

(2008) Maureen A. Su et al.   JOURNAL OF CLINICAL INVESTIGATION

Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance

(2008) Masashi Yano et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Promiscuous gene expression patterns in single medullary thymic epithelial cells argue for a stochastic mechanism

(2008) J. Derbinski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deletional Tolerance Mediated by Extrathymic Aire-Expressing Cells

(2008) J. M. Gardner et al.   SCIENCE

DNA-PK contributes to the phosphorylation of AIRE: Importance in transcriptional activity

(2007) Ingrid Liiv et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH