Aire mediates thymic expression and tolerance of pancreatic antigens via an unconventional transcriptional mechanism

The Lymphotoxin Pathway Regulates Aire-Independent Expression of Ectopic Genes and Chemokines in Thymic Stromal Cells

(2014) N. Seach et al.   JOURNAL OF IMMUNOLOGY

Alterations of the Medullary Epithelial Compartment in the Aire-Deficient Thymus: Implications for Programs of Thymic Epithelial Differentiation

(2014) J. Dooley et al.   JOURNAL OF IMMUNOLOGY

Aire regulates the transfer of antigen from mTECs to dendritic cells for induction of thymic tolerance

(2011) F.-X. Hubert et al.   BLOOD

Aire unleashes stalled RNA polymerase to induce ectopic gene expression in thymic epithelial cells

(2011) M. Giraud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Models of Aire-Dependent Gene Regulation for Thymic Negative Selection

(2011) Dina Danso-Abeam et al.   Frontiers in Immunology

Aire's Partners in the Molecular Control of Immunological Tolerance

(2010) Jakub Abramson et al.   CELL

Contrasting models for the roles of Aire in the differentiation program of epithelial cells in the thymic medulla

(2010) Mitsuru Matsumoto   EUROPEAN JOURNAL OF IMMUNOLOGY

Aire

(2009) Diane Mathis et al.   Annual Review of Immunology

Thymus-specific deletion of insulin induces autoimmune diabetes

(2009) Yong Fan et al.   EMBO JOURNAL

pdx-1 function is specifically required in embryonic β cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis

(2008) Maureen Gannon et al.   DEVELOPMENTAL BIOLOGY

Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire

(2008) Maureen A. Su et al.   JOURNAL OF CLINICAL INVESTIGATION

Ectopic expression of peripheral-tissue antigens in the thymic epithelium: Probabilistic, monoallelic, misinitiated

(2008) J. Villasenor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity

(2008) A. S. Koh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unbiased analysis, enrichment and purification of thymic stromal cells

(2007) Daniel H.D. Gray et al.   JOURNAL OF IMMUNOLOGICAL METHODS