Macroautophagy substrates are loaded onto MHC class II of medullary thymic epithelial cells for central tolerance

Differential processing of self-antigens by subsets of thymic stromal cells

(2012) Sylvie Guerder et al.   CURRENT OPINION IN IMMUNOLOGY

Chaperone-mediated autophagy: a unique way to enter the lysosome world

(2012) Susmita Kaushik et al.   TRENDS IN CELL BIOLOGY

Aire regulates the transfer of antigen from mTECs to dendritic cells for induction of thymic tolerance

(2011) F.-X. Hubert et al.   BLOOD

Autonomous versus dendritic cell-dependent contributions of medullary thymic epithelial cells to central tolerance

(2011) Ludger Klein et al.   TRENDS IN IMMUNOLOGY

Autonomous role of medullary thymic epithelial cells in central CD4+ T cell tolerance

(2010) Maria Hinterberger et al.   NATURE IMMUNOLOGY

Macroautophagy, endogenous MHC II loading and T cell selection: the benefits of breaking the rules

(2009) Jelena Nedjic et al.   CURRENT OPINION IN IMMUNOLOGY

The thymic medulla: a unique microenvironment for intercellular self-antigen transfer

(2009) Christian Koble et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity

(2009) Caspar Ohnmacht et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Autophagic Compartments Gain Access to the MHC Class II Compartments in Thymic Epithelium

(2009) M. Kasai et al.   JOURNAL OF IMMUNOLOGY

Regulatory T cell differentiation of thymocytes does not require a dedicated antigen-presenting cell but is under T cell-intrinsic developmental control

(2009) G. Wirnsberger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhancing Immunity Through Autophagy

(2008) Christian Münz   Annual Review of Immunology

Endogenous presentation of a nuclear antigen on MHC class II by autophagy in the absence of CRM1-mediated nuclear export

(2008) Alexander Riedel et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance

(2008) Jelena Nedjic et al.   NATURE