Epigenetic Regulation of Interleukin 6 by Histone Acetylation in Macrophages and Its Role in Paraquat-Induced Pulmonary Fibrosis
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Epigenetic Regulation of Interleukin 6 by Histone Acetylation in Macrophages and Its Role in Paraquat-Induced Pulmonary Fibrosis
Authors
Keywords
-
Journal
Frontiers in Immunology
Volume 7, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2017-01-30
DOI
10.3389/fimmu.2016.00696
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- STAT-3 contributes to pulmonary fibrosis through epithelial injury and fibroblast-myofibroblast differentiation
- (2016) Mesias Pedroza et al. FASEB JOURNAL
- CRISPR-on system for the activation of the endogenous human INS gene
- (2016) C A Giménez et al. GENE THERAPY
- HDAC Inhibitors as Epigenetic Regulators of the Immune System: Impacts on Cancer Therapy and Inflammatory Diseases
- (2016) Elizabeth E. Hull et al. Biomed Research International
- Endothelial to Mesenchymal Transition (EndoMT) in the Pathogenesis of Human Fibrotic Diseases
- (2016) Sonsoles Piera-Velazquez et al. Journal of Clinical Medicine
- Epigenetics in autoimmune diseases: Pathogenesis and prospects for therapy
- (2015) Zimu Zhang et al. AUTOIMMUNITY REVIEWS
- Biological effects of interleukin-6: Clinical applications in autoimmune diseases and cancers
- (2015) Ling-Jun Ho et al. BIOCHEMICAL PHARMACOLOGY
- Alcohol-induced histone H3K9 hyperacetylation and cardiac hypertrophy are reversed by a histone acetylases inhibitor anacardic acid in developing murine hearts
- (2015) Chang Peng et al. BIOCHIMIE
- Histone deacetylase inhibitor restores surfactant protein-C expression in alveolar-epithelial type II cells and attenuates bleomycin-induced pulmonary fibrosisin vivo
- (2015) Chiharu Ota et al. EXPERIMENTAL LUNG RESEARCH
- The anacardic 6-pentadecyl salicylic acid induces macrophage activation via the phosphorylation of ERK1/2, JNK, P38 kinases and NF-κB
- (2015) J.N. Rashida Gnanaprakasam et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Epigenetic mechanisms: An emerging role in pathogenesis and its therapeutic potential in systemic sclerosis
- (2015) Yangyang Luo et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Anti-Fibrotic Effects of Class I HDAC Inhibitor, Mocetinostat Is Associated with IL-6/Stat3 Signaling in Ischemic Heart Failure
- (2015) Hikmet Nural-Guvener et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Effects of rapamycin against paraquat-induced pulmonary fibrosis in mice
- (2015) Xue Shao et al. Journal of Zhejiang University-SCIENCE B
- Involvement of epithelial-to-mesenchymal transition and associated transforming growth factor-β/Smad signaling in paraquat-induced pulmonary fibrosis
- (2015) YING-YING HAN et al. Molecular Medicine Reports
- Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
- (2015) Silvana Konermann et al. NATURE
- Interleukin-6/interleukin-21 signaling axis is critical in the pathogenesis of pulmonary arterial hypertension
- (2015) Takahiro Hashimoto-Kataoka et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Aberrant expression and activity of histone deacetylases in sporadic idiopathic pulmonary fibrosis
- (2015) Martina Korfei et al. THORAX
- Epigenetics of idiopathic pulmonary fibrosis
- (2015) Ivana V. Yang et al. Translational Research
- Paraquat Induces Epithelial-Mesenchymal Transition-Like Cellular Response Resulting in Fibrogenesis and the Prevention of Apoptosis in Human Pulmonary Epithelial Cells
- (2015) Atsushi Yamada et al. PLoS One
- Histone Deacetylase Regulates Trypsin Activation, Inflammation, and Tissue Damage in Acute Pancreatitis in Mice
- (2014) Hannes Hartman et al. DIGESTIVE DISEASES AND SCIENCES
- Vascular histone deacetylation by pharmacological HDAC inhibition
- (2014) Haloom Rafehi et al. GENOME RESEARCH
- Interleukin-6 Signaling Drives Fibrosis in Unresolved Inflammation
- (2014) Ceri A. Fielding et al. IMMUNITY
- Interleukin-6 (IL-6) Trans Signaling Drives a STAT3-dependent Pathway That Leads to Hyperactive Transforming Growth Factor-β (TGF-β) Signaling Promoting SMAD3 Activation and Fibrosis via Gremlin Protein
- (2014) Steven O'Reilly et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Blockade of IL-6TransSignaling Attenuates Pulmonary Fibrosis
- (2014) Thanh-Thuy T. Le et al. JOURNAL OF IMMUNOLOGY
- Targeting cardiac fibroblasts to treat fibrosis of the heart: Focus on HDACs
- (2014) Katherine B. Schuetze et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells
- (2014) Xuebing Wu et al. NATURE BIOTECHNOLOGY
- The Pro-Inflammatory Cytokine, Interleukin-6, Enhances the Polarization of Alternatively Activated Macrophages
- (2014) Maria Ruweka Fernando et al. PLoS One
- Inhibition of Histone H3K9 Acetylation by Anacardic Acid Can Correct the Over-Expression of Gata4 in the Hearts of Fetal Mice Exposed to Alcohol during Pregnancy
- (2014) Chang Peng et al. PLoS One
- Targeting IL-6 by both passive or active immunization strategies prevents bleomycin-induced skin fibrosis
- (2014) Lucille Desallais et al. ARTHRITIS RESEARCH & THERAPY
- Narrative Review: Fibrotic Diseases: Cellular and Molecular Mechanisms and Novel Therapies
- (2013) Joel Rosenbloom ANNALS OF INTERNAL MEDICINE
- Effect of Methylsulfonylmethane on Paraquat-Induced Acute Lung and Liver Injury in Mice
- (2013) Keyvan Amirshahrokhi et al. INFLAMMATION
- Novel therapeutic strategies for lung disorders associated with airway remodelling and fibrosis
- (2013) Simon G. Royce et al. PHARMACOLOGY & THERAPEUTICS
- Comparison of trichostatin A and valproic acid treatment regimens in a mouse model of kidney fibrosis
- (2013) Katrien Van Beneden et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- STAT3-Mediated Signaling Dysregulates Lung Fibroblast-Myofibroblast Activation and Differentiation in UIP/IPF
- (2012) Dmitri V. Pechkovsky et al. AMERICAN JOURNAL OF PATHOLOGY
- Epigenetic reprogramming and post-transcriptional regulation during the epithelial–mesenchymal transition
- (2012) Chung-Yin Wu et al. TRENDS IN GENETICS
- Suppression of Histone Deacetylases Worsens Right Ventricular Dysfunction after Pulmonary Artery Banding in Rats
- (2011) Harm J. Bogaard et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Idiopathic pulmonary fibrosis
- (2011) Talmadge E King et al. LANCET
- Histone Deacetylase: A Potential Therapeutic Target for Fibrotic Disorders
- (2010) M. Pang et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- STAT3 in tissue fibrosis: Is there a role in the lung?
- (2010) Darryl Knight et al. PULMONARY PHARMACOLOGY & THERAPEUTICS
- IL-6 loss causes ventricular dysfunction, fibrosis, reduced capillary density, and dramatically alters the cell populations of the developing and adult heart
- (2009) Indroneal Banerjee et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Abrogation of TGF-β1-induced fibroblast-myofibroblast differentiation by histone deacetylase inhibition
- (2009) Weichao Guo et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Chronic administration of valproic acid inhibits activation of mouse hepatic stellate cellsin vitroandin vivo
- (2009) Inge Mannaerts et al. HEPATOLOGY
- Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease
- (2009) Hervé Acloque et al. JOURNAL OF CLINICAL INVESTIGATION
- Defective Histone Acetylation Is Responsible for the Diminished Expression of Cyclooxygenase 2 in Idiopathic Pulmonary Fibrosis
- (2009) W. R. Coward et al. MOLECULAR AND CELLULAR BIOLOGY
- Pulmonary fibrosis: pathogenesis, etiology and regulation
- (2009) M S Wilson et al. Mucosal Immunology
- Inhibition of Interleukin-6-Transsignaling via gp130-Fc in Hemorrhagic Shock and Sepsis
- (2008) Soeren Torge Mees et al. JOURNAL OF SURGICAL RESEARCH
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started