标题
Metabolic Modulation in Macrophage Effector Function
作者
关键词
-
出版物
Frontiers in Immunology
Volume 9, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2018-02-19
DOI
10.3389/fimmu.2018.00270
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Cellular metabolism of tumor-associated macrophages - functional impact and consequences
- (2017) Katrin Rabold et al. FEBS LETTERS
- Krebs cycle rewired for macrophage and dendritic cell effector functions
- (2017) Dylan Gerard Ryan et al. FEBS LETTERS
- The Induction of Pro–IL-1β by Lipopolysaccharide Requires Endogenous Prostaglandin E2Production
- (2017) Zbigniew Zasłona et al. JOURNAL OF IMMUNOLOGY
- Higher phagocytic activity of thioglycollate-elicited peritoneal macrophages is related to metabolic status of the cells
- (2017) Sofia Pavlou et al. Journal of Inflammation-London
- Glucose feeds the TCA cycle via circulating lactate
- (2017) Sheng Hui et al. NATURE
- Differential Regulation of Macrophage Glucose Metabolism by Macrophage Colony-stimulating Factor and Granulocyte-Macrophage Colony-stimulating Factor: Implications for 18F FDG PET Imaging of Vessel Wall Inflammation
- (2017) Sina Tavakoli et al. RADIOLOGY
- Anti-inflammatory effect of IL-10 mediated by metabolic reprogramming of macrophages
- (2017) W. K. Eddie Ip et al. SCIENCE
- BCAT1 controls metabolic reprogramming in activated human macrophages and is associated with inflammatory diseases
- (2017) Adonia E. Papathanassiu et al. Nature Communications
- Epigenetic Regulation of Interleukin 6 by Histone Acetylation in Macrophages and Its Role in Paraquat-Induced Pulmonary Fibrosis
- (2017) Lingli Hu et al. Frontiers in Immunology
- Pyruvate Kinase M2 Is Required for the Expression of the Immune Checkpoint PD-L1 in Immune Cells and Tumors
- (2017) Eva M. Palsson-McDermott et al. Frontiers in Immunology
- Arginine Metabolism in Myeloid Cells Shapes Innate and Adaptive Immunity
- (2017) Paulo C. Rodriguez et al. Frontiers in Immunology
- GPR91 deficiency exacerbates allergic contact dermatitis while reducing arthritic disease in mice
- (2016) T. Rubić-Schneider et al. ALLERGY
- miR-125b controls monocyte adaptation to inflammation through mitochondrial metabolism and dynamics
- (2016) I. Duroux-Richard et al. BLOOD
- Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages
- (2016) Evanna L. Mills et al. CELL
- Hexokinase Is an Innate Immune Receptor for the Detection of Bacterial Peptidoglycan
- (2016) Andrea J. Wolf et al. CELL
- Macrophage Metabolism Controls Tumor Blood Vessel Morphogenesis and Metastasis
- (2016) Mathias Wenes et al. Cell Metabolism
- Mitochondrial ROS Produced via Reverse Electron Transport Extend Animal Lifespan
- (2016) Filippo Scialò et al. Cell Metabolism
- Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation
- (2016) Vicky Lampropoulou et al. Cell Metabolism
- Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity
- (2016) Rob J.W. Arts et al. Cell Metabolism
- Abolition of mitochondrial substrate-level phosphorylation by itaconic acid produced by LPS-induced Irg1 expression in cells of murine macrophage lineage
- (2016) Beáta Németh et al. FASEB JOURNAL
- K + Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria
- (2016) Christina J. Groß et al. IMMUNITY
- Targeting T Cell Co-receptors for Cancer Therapy
- (2016) Margaret K. Callahan et al. IMMUNITY
- Metabolic Reprogramming Mediated by the mTORC2-IRF4 Signaling Axis Is Essential for Macrophage Alternative Activation
- (2016) Stanley Ching-Cheng Huang et al. IMMUNITY
- Immunoresponsive Gene 1 and Itaconate Inhibit Succinate Dehydrogenase to Modulate Intracellular Succinate Levels
- (2016) Thekla Cordes et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- GPR91 senses extracellular succinate released from inflammatory macrophages and exacerbates rheumatoid arthritis
- (2016) Amanda Littlewood-Evans et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The glycolytic enzyme PKM2 bridges metabolic and inflammatory dysfunction in coronary artery disease
- (2016) Tsuyoshi Shirai et al. JOURNAL OF EXPERIMENTAL MEDICINE
- GAPDH Binding to TNF-α mRNA Contributes to Posttranscriptional Repression in Monocytes: A Novel Mechanism of Communication between Inflammation and Metabolism
- (2016) Patrick Millet et al. JOURNAL OF IMMUNOLOGY
- Comprehensive Proteomics Analysis Reveals Metabolic Reprogramming of Tumor-Associated Macrophages Stimulated by the Tumor Microenvironment
- (2016) Di Liu et al. JOURNAL OF PROTEOME RESEARCH
- Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis
- (2016) Shih-Chin Cheng et al. NATURE IMMUNOLOGY
- Mitochondrial respiratory-chain adaptations in macrophages contribute to antibacterial host defense
- (2016) Johan Garaude et al. NATURE IMMUNOLOGY
- Fatty acid oxidation in macrophage polarization
- (2016) Mitsunori Nomura et al. NATURE IMMUNOLOGY
- C13orf31 (FAMIN) is a central regulator of immunometabolic function
- (2016) M Zaeem Cader et al. NATURE IMMUNOLOGY
- NOX4-dependent fatty acid oxidation promotes NLRP3 inflammasome activation in macrophages
- (2016) Jong-Seok Moon et al. NATURE MEDICINE
- HIF-1α-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacity
- (2016) Hiroaki Semba et al. Nature Communications
- PKM2-dependent glycolysis promotes NLRP3 and AIM2 inflammasome activation
- (2016) Min Xie et al. Nature Communications
- Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages
- (2016) Jan Van den Bossche et al. Cell Reports
- IFNs Modify the Proteome of Legionella-Containing Vacuoles and Restrict Infection Via IRG1-Derived Itaconic Acid
- (2016) Jan Naujoks et al. PLoS Pathogens
- Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation
- (2016) Anthony J Covarrubias et al. eLife
- Warburg metabolism in tumor-conditioned macrophages promotes metastasis in human pancreatic ductal adenocarcinoma
- (2016) Hweixian Leong Penny et al. OncoImmunology
- Autocrine IL-10 functions as a rheostat for M1 macrophage glycolytic commitment by tuning nitric oxide production
- (2016) Walter A. Baseler et al. Redox Biology
- Enhanced fatty acid oxidation in adipocytes and macrophages reduces lipid-induced triglyceride accumulation and inflammation
- (2015) Maria Ida Malandrino et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Oxygen Sensing by Arterial Chemoreceptors Depends on Mitochondrial Complex I Signaling
- (2015) M. Carmen Fernández-Agüera et al. Cell Metabolism
- Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages
- (2015) Eva M. Palsson-McDermott et al. Cell Metabolism
- IRG1 induced by heme oxygenase-1/carbon monoxide inhibits LPS-mediated sepsis and pro-inflammatory cytokine production
- (2015) Md Jamal Uddin et al. Cellular & Molecular Immunology
- Network Integration of Parallel Metabolic and Transcriptional Data Reveals Metabolic Modules that Regulate Macrophage Polarization
- (2015) Abhishek K. Jha et al. IMMUNITY
- Metformin Inhibits the Production of Reactive Oxygen Species from NADH:Ubiquinone Oxidoreductase to Limit Induction of Interleukin-1β (IL-1β) and Boosts Interleukin-10 (IL-10) in Lipopolysaccharide (LPS)-activated Macrophages
- (2015) Beth Kelly et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Pro-inflammatory Macrophages Sustain Pyruvate Oxidation through Pyruvate Dehydrogenase for the Synthesis of Itaconate and to Enable Cytokine Expression
- (2015) Johannes Meiser et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- UCP2-induced fatty acid synthase promotes NLRP3 inflammasome activation during sepsis
- (2015) Jong-Seok Moon et al. JOURNAL OF CLINICAL INVESTIGATION
- Differential Requirements for l-Citrulline and l-Arginine during Antimycobacterial Macrophage Activity
- (2015) Shannon M. Rapovy et al. JOURNAL OF IMMUNOLOGY
- Pyruvate Dehydrogenase Kinase 1 Participates in Macrophage Polarization via Regulating Glucose Metabolism
- (2015) Zheng Tan et al. JOURNAL OF IMMUNOLOGY
- Metabolic Regulation by Lysine Malonylation, Succinylation, and Glutarylation
- (2015) Matthew D. Hirschey et al. MOLECULAR & CELLULAR PROTEOMICS
- Amino acid auxotrophy as a system of immunological control nodes
- (2015) Peter J Murray NATURE IMMUNOLOGY
- mTORC1-Induced HK1-Dependent Glycolysis Regulates NLRP3 Inflammasome Activation
- (2015) Jong-Seok Moon et al. Cell Reports
- Metabolic Characterization of Polarized M1 and M2 Bone Marrow-derived Macrophages Using Real-time Extracellular Flux Analysis
- (2015) Jan Van den Bossche et al. Jove-Journal of Visualized Experiments
- Time and Demand are Two Critical Dimensions of Immunometabolism: The Process of Macrophage Activation and the Pentose Phosphate Pathway
- (2015) Csörsz Nagy et al. Frontiers in Immunology
- Pyruvate kinase M2 regulates glucose metabolism by functioning as a coactivator for hypoxia-inducible factor 1 in cancer cells
- (2015) Weibo Luo et al. Oncotarget
- A key role of the mitochondrial citrate carrier (SLC25A1) in TNFα- and IFNγ-triggered inflammation
- (2014) Vittoria Infantino et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- ROS-Triggered Phosphorylation of Complex II by Fgr Kinase Regulates Cellular Adaptation to Fuel Use
- (2014) Rebeca Acín-Pérez et al. Cell Metabolism
- Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation
- (2014) Jia Xue et al. IMMUNITY
- Metabolic Reprogramming of Macrophages
- (2014) Alex J. Freemerman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Lysine Malonylation Is Elevated in Type 2 Diabetic Mouse Models and Enriched in Metabolic Associated Proteins
- (2014) Yipeng Du et al. MOLECULAR & CELLULAR PROTEOMICS
- Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
- (2014) Oscar R. Colegio et al. NATURE
- Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS
- (2014) Edward T. Chouchani et al. NATURE
- Bacterial itaconate degradation promotes pathogenicity
- (2014) Jahminy Sasikaran et al. Nature Chemical Biology
- Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages
- (2014) Stanley Ching-Cheng Huang et al. NATURE IMMUNOLOGY
- mTOR- and HIF-1 -mediated aerobic glycolysis as metabolic basis for trained immunity
- (2014) S.-C. Cheng et al. SCIENCE
- Microtubule acetylation amplifies p38 kinase signalling and anti-inflammatory IL-10 production
- (2014) Bin Wang et al. Nature Communications
- PKM2 regulates the Warburg effect and promotes HMGB1 release in sepsis
- (2014) Liangchun Yang et al. Nature Communications
- Mitochondrial Respiratory Supercomplex Association Limits Production of Reactive Oxygen Species from Complex I
- (2013) Evelina Maranzana et al. ANTIOXIDANTS & REDOX SIGNALING
- ATP-citrate lyase is essential for macrophage inflammatory response
- (2013) Vittoria Infantino et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
- (2013) Chih-Hao Chang et al. CELL
- Immunoresponsive Gene 1 Augments Bactericidal Activity of Macrophage-Lineage Cells by Regulating β-Oxidation-Dependent Mitochondrial ROS Production
- (2013) Christopher J. Hall et al. Cell Metabolism
- NLRP3 and IL-1βin macrophages as critical regulators of metabolic diseases
- (2013) A. F. McGettrick et al. DIABETES OBESITY & METABOLISM
- Asymmetric dimethylarginine regulates the lipopolysaccharide-induced nitric oxide production in macrophages by suppressing the activation of NF-kappaB and iNOS expression
- (2013) Michaela Pekarova et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Immune Responsive Gene 1 (IRG1) Promotes Endotoxin Tolerance by Increasing A20 Expression in Macrophages through Reactive Oxygen Species
- (2013) Yingke Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Succinate is an inflammatory signal that induces IL-1β through HIF-1α
- (2013) G. M. Tannahill et al. NATURE
- Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production
- (2013) A. Michelucci et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Supercomplex Assembly Determines Electron Flux in the Mitochondrial Electron Transport Chain
- (2013) E. Lapuente-Brun et al. SCIENCE
- Arginase Activity in the Blood of Patients with Visceral Leishmaniasis and HIV Infection
- (2013) Yegnasew Takele et al. PLoS Neglected Tropical Diseases
- Regulation of Immune Responses by mTOR
- (2012) Jonathan D. Powell et al. Annual Review of Immunology
- The Sedoheptulose Kinase CARKL Directs Macrophage Polarization through Control of Glucose Metabolism
- (2012) Arvand Haschemi et al. Cell Metabolism
- Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling
- (2012) Paul D. Ray et al. CELLULAR SIGNALLING
- The unique role of dietary l-arginine in the acceleration of peritoneal macrophage sensitivity to bacterial endotoxin
- (2012) Michaela Pekarova et al. IMMUNOLOGIC RESEARCH
- Amino acid catabolism: a pivotal regulator of innate and adaptive immunity
- (2012) Tracy L. McGaha et al. IMMUNOLOGICAL REVIEWS
- -Enolase Expressed on the Surfaces of Monocytes and Macrophages Induces Robust Synovial Inflammation in Rheumatoid Arthritis
- (2012) S. Bae et al. JOURNAL OF IMMUNOLOGY
- Mechanisms of triglyceride accumulation in activated macrophages
- (2012) Kenneth R. Feingold et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Heterotrimeric GAIT Complex Drives Transcript-Selective Translation Inhibition in Murine Macrophages
- (2012) A. Arif et al. MOLECULAR AND CELLULAR BIOLOGY
- Novel role of PKR in inflammasome activation and HMGB1 release
- (2012) Ben Lu et al. NATURE
- The mitochondrial citrate carrier: a new player in inflammation
- (2011) Vittoria Infantino et al. BIOCHEMICAL JOURNAL
- Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)
- (2011) Ariel C. Bulua et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Arginine transport in human monocytic leukemia THP-1 cells during macrophage differentiation
- (2011) Amelia Barilli et al. JOURNAL OF LEUKOCYTE BIOLOGY
- 1H NMR-based Metabolomic Profiling in Mice Infected withMycobacterium tuberculosis
- (2011) Ji-Hyun Shin et al. JOURNAL OF PROTEOME RESEARCH
- Itaconic Acid Is a Mammalian Metabolite Induced during Macrophage Activation
- (2011) Cheryl L. Strelko et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Non-targeted metabolite profiling in activated macrophage secretion
- (2011) Masahiro Sugimoto et al. Metabolomics
- The First Identification of Lysine Malonylation Substrates and Its Regulatory Enzyme
- (2011) Chao Peng et al. MOLECULAR & CELLULAR PROTEOMICS
- TLR signalling augments macrophage bactericidal activity through mitochondrial ROS
- (2011) A. Phillip West et al. NATURE
- Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling
- (2011) Haitao Wen et al. NATURE IMMUNOLOGY
- New Role for L-Arginine in Regulation of Inducible Nitric-Oxide-Synthase-Derived Superoxide Anion Production in Raw 264.7 Macrophages
- (2011) Michaela Pekarova et al. TheScientificWorldJOURNAL
- Differential activation and antagonistic function of HIF- isoforms in macrophages are essential for NO homeostasis
- (2010) N. Takeda et al. GENES & DEVELOPMENT
- Substrate Fate in Activated Macrophages: A Comparison between Innate, Classic, and Alternative Activation
- (2010) J.-C. Rodriguez-Prados et al. JOURNAL OF IMMUNOLOGY
- A role for mitochondria in NLRP3 inflammasome activation
- (2010) Rongbin Zhou et al. NATURE
- NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
- (2010) Peter Duewell et al. NATURE
- Cholesterol Crystals Activate the NLRP3 Inflammasome in Human Macrophages: A Novel Link between Cholesterol Metabolism and Inflammation
- (2010) Kristiina Rajamäki et al. PLoS One
- The Intracellular Sensor NLRP3 Mediates Key Innate and Healing Responses to Influenza A Virus via the Regulation of Caspase-1
- (2009) Paul G. Thomas et al. IMMUNITY
- Translational repression of inducible NO synthase in macrophages by l-arginine depletion is not associated with an increased phosphorylation of eIF2α
- (2009) Till König et al. IMMUNOBIOLOGY
- Neisseria gonorrhoeae Activates the Proteinase Cathepsin B to Mediate the Signaling Activities of the NLRP3 and ASC-Containing Inflammasome
- (2009) Joseph A. Duncan et al. JOURNAL OF IMMUNOLOGY
- Arginase-1–Expressing Macrophages Suppress Th2 Cytokine–Driven Inflammation and Fibrosis
- (2009) John T. Pesce et al. PLoS Pathogens
- The Proinflammatory Cytokine-Induced IRG1 Protein Associates with Mitochondria
- (2008) Daniel Degrandi et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α
- (2008) Jordi Rius et al. NATURE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More