Cellular metabolism of tumor-associated macrophages - functional impact and consequences
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Title
Cellular metabolism of tumor-associated macrophages - functional impact and consequences
Authors
Keywords
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Journal
FEBS LETTERS
Volume 591, Issue 19, Pages 3022-3041
Publisher
Wiley
Online
2017-08-04
DOI
10.1002/1873-3468.12771
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Note: Only part of the references are listed.- Tumor-associated macrophages: from basic research to clinical application
- (2017) Li Yang et al. Journal of Hematology & Oncology
- Class IIa HDAC inhibition reduces breast tumours and metastases through anti-tumour macrophages
- (2017) Jennifer L. Guerriero et al. NATURE
- Lipocalin-2 and iron trafficking in the tumor microenvironment
- (2017) Michaela Jung et al. PHARMACOLOGICAL RESEARCH
- Ornithine decarboxylase regulates M1 macrophage activation and mucosal inflammation via histone modifications
- (2017) Dana M. Hardbower et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Macrophage Metabolism Controls Tumor Blood Vessel Morphogenesis and Metastasis
- (2016) Mathias Wenes et al. Cell Metabolism
- Reprogramming mitochondrial metabolism in macrophages as an anti-inflammatory signal
- (2016) Evanna L. Mills et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Metabolic Reprogramming Mediated by the mTORC2-IRF4 Signaling Axis Is Essential for Macrophage Alternative Activation
- (2016) Stanley Ching-Cheng Huang et al. IMMUNITY
- Expression Profiling of Macrophages Reveals Multiple Populations with Distinct Biological Roles in an Immunocompetent Orthotopic Model of Lung Cancer
- (2016) Joanna M. Poczobutt et al. JOURNAL OF IMMUNOLOGY
- Comprehensive Proteomics Analysis Reveals Metabolic Reprogramming of Tumor-Associated Macrophages Stimulated by the Tumor Microenvironment
- (2016) Di Liu et al. JOURNAL OF PROTEOME RESEARCH
- New insights into the multidimensional concept of macrophage ontogeny, activation and function
- (2016) Florent Ginhoux et al. NATURE IMMUNOLOGY
- Molecular targets of metformin antitumor action
- (2016) Stanisław Sośnicki et al. Pharmacological Reports
- Intracellular Iron Chelation Modulates the Macrophage Iron Phenotype with Consequences on Tumor Progression
- (2016) Christina Mertens et al. PLoS One
- Integrating immunometabolism and macrophage diversity
- (2016) Maxim N. Artyomov et al. SEMINARS IN IMMUNOLOGY
- Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages
- (2016) Jan Van den Bossche et al. Cell Reports
- Transcriptional and metabolic reprogramming induce an inflammatory phenotype in non-medullary thyroid carcinoma-induced macrophages
- (2016) Rob J. W. Arts et al. OncoImmunology
- Anti-GD2 mAb and Vorinostat synergize in the treatment of neuroblastoma
- (2016) Michiel Kroesen et al. OncoImmunology
- Warburg metabolism in tumor-conditioned macrophages promotes metastasis in human pancreatic ductal adenocarcinoma
- (2016) Hweixian Leong Penny et al. OncoImmunology
- Microbial stimulation of different Toll-like receptor signalling pathways induces diverse metabolic programmes in human monocytes
- (2016) Ekta Lachmandas et al. Nature Microbiology
- Metabolic communication in tumors: a new layer of immunoregulation for immune evasion
- (2016) Ping-Chih Ho et al. Journal for ImmunoTherapy of Cancer
- Enhanced fatty acid oxidation in adipocytes and macrophages reduces lipid-induced triglyceride accumulation and inflammation
- (2015) Maria Ida Malandrino et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Glioblastoma cells induce differential glutamatergic gene expressions in human tumor-associated microglia/macrophages and monocyte-derived macrophages
- (2015) Judy Choi et al. CANCER BIOLOGY & THERAPY
- M-CSF and GM-CSF Receptor Signaling Differentially Regulate Monocyte Maturation and Macrophage Polarization in the Tumor Microenvironment
- (2015) E. Van Overmeire et al. CANCER RESEARCH
- Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages
- (2015) Eva M. Palsson-McDermott et al. Cell Metabolism
- Network Integration of Parallel Metabolic and Transcriptional Data Reveals Metabolic Modules that Regulate Macrophage Polarization
- (2015) Abhishek K. Jha et al. IMMUNITY
- Macrophage iron homeostasis and polarization in the context of cancer
- (2015) Michaela Jung et al. IMMUNOBIOLOGY
- Ovarian cancer stem cells induce the M2 polarization of macrophages through the PPARγ and NF-κB pathways
- (2015) XINCHAO DENG et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Palmitoleate Reverses High Fat-induced Proinflammatory Macrophage Polarization via AMP-activated Protein Kinase (AMPK)
- (2015) Kenny L. Chan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- UCP2-induced fatty acid synthase promotes NLRP3 inflammasome activation during sepsis
- (2015) Jong-Seok Moon et al. JOURNAL OF CLINICAL INVESTIGATION
- Immunometabolism governs dendritic cell and macrophage function
- (2015) Luke A.J. O’Neill et al. JOURNAL OF EXPERIMENTAL MEDICINE
- CD147 reprograms fatty acid metabolism in hepatocellular carcinoma cells through Akt/mTOR/SREBP1c and P38/PPARα pathways
- (2015) Jibin Li et al. JOURNAL OF HEPATOLOGY
- Control of macrophage metabolism and activation by mTOR and Akt signaling
- (2015) Anthony J. Covarrubias et al. SEMINARS IN IMMUNOLOGY
- Inhibition of tumor growth by a newly-identified activator for epidermal fatty acid binding protein
- (2015) Enyu Rao et al. Oncotarget
- Deregulation of PPARβ/δ target genes in tumor-associated macrophages by fatty acid ligands in the ovarian cancer microenvironment
- (2015) Tim Schumann et al. Oncotarget
- Metformin Reduces Desmoplasia in Pancreatic Cancer by Reprogramming Stellate Cells and Tumor-Associated Macrophages
- (2015) Joao Incio et al. PLoS One
- Fatty Acid-Binding Protein E-FABP Restricts Tumor Growth by Promoting IFN- Responses in Tumor-Associated Macrophages
- (2014) Y. Zhang et al. CANCER RESEARCH
- Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines
- (2014) Peter J. Murray et al. IMMUNITY
- Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation
- (2014) Jia Xue et al. IMMUNITY
- Molecular Profiling Reveals a Tumor-Promoting Phenotype of Monocytes and Macrophages in Human Cancer Progression
- (2014) Manesh Chittezhath et al. IMMUNITY
- Metabolism of stromal and immune cells in health and disease
- (2014) Bart Ghesquière et al. NATURE
- Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
- (2014) Oscar R. Colegio et al. NATURE
- Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages
- (2014) Stanley Ching-Cheng Huang et al. NATURE IMMUNOLOGY
- Increased metabolites of 5-lipoxygenase from hypoxic ovarian cancer cells promote tumor-associated macrophage infiltration
- (2014) Z Wen et al. ONCOGENE
- Amino acids – A life between metabolism and signaling
- (2014) Rainer E. Häusler et al. PLANT SCIENCE
- The pentose phosphate pathway and cancer
- (2014) Krushna C. Patra et al. TRENDS IN BIOCHEMICAL SCIENCES
- Metabolism via Arginase or Nitric Oxide Synthase: Two Competing Arginine Pathways in Macrophages
- (2014) Meera Rath et al. Frontiers in Immunology
- Interleukin-4- and Interleukin-13-Mediated Alternatively Activated Macrophages: Roles in Homeostasis and Disease
- (2013) Steven J. Van Dyken et al. Annual Review of Immunology
- Hypoxia enhances lipid uptake in macrophages: Role of the scavenger receptors Lox1, SRA, and CD36
- (2013) Margot Crucet et al. ATHEROSCLEROSIS
- Impeding Macrophage Entry into Hypoxic Tumor Areas by Sema3A/Nrp1 Signaling Blockade Inhibits Angiogenesis and Restores Antitumor Immunity
- (2013) Andrea Casazza et al. CANCER CELL
- Rottlerin induces autophagy and apoptosis in prostate cancer stem cells via PI3K/Akt/mTOR signaling pathway
- (2013) Dhruv Kumar et al. CANCER LETTERS
- Tumor Hypoxia Does Not Drive Differentiation of Tumor-Associated Macrophages but Rather Fine-Tunes the M2-like Macrophage Population
- (2013) D. Laoui et al. CANCER RESEARCH
- Hooked on fat: the role of lipid synthesis in cancer metabolism and tumour development
- (2013) F. Baenke et al. Disease Models & Mechanisms
- Metabolism of inflammation limited by AMPK and pseudo-starvation
- (2013) Luke A. J. O'Neill et al. NATURE
- Succinate is an inflammatory signal that induces IL-1β through HIF-1α
- (2013) G. M. Tannahill et al. NATURE
- Fatty acid–induced mitochondrial uncoupling elicits inflammasome-independent IL-1α and sterile vascular inflammation in atherosclerosis
- (2013) Stefan Freigang et al. NATURE IMMUNOLOGY
- Osteopontin signaling upregulates cyclooxygenase-2 expression in tumor-associated macrophages leading to enhanced angiogenesis and melanoma growth via α9β1 integrin
- (2013) S Kale et al. ONCOGENE
- Inhibition of Tumor Growth and Alteration of Associated Macrophage Cell Type by an HO-1 Inhibitor in Breast Carcinoma-Bearing Mice
- (2013) Rui Deng et al. ONCOLOGY RESEARCH
- Eicosanoid Profiling in an Orthotopic Model of Lung Cancer Progression by Mass Spectrometry Demonstrates Selective Production of Leukotrienes by Inflammatory Cells of the Microenvironment
- (2013) Joanna M. Poczobutt et al. PLoS One
- Emergence of spatial structure in the tumor microenvironment due to the Warburg effect
- (2013) C. Carmona-Fontaine et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production
- (2013) A. Michelucci et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tumor-associated macrophages: functional diversity, clinical significance, and open questions
- (2013) Subhra K. Biswas et al. Seminars in Immunopathology
- The Sedoheptulose Kinase CARKL Directs Macrophage Polarization through Control of Glucose Metabolism
- (2012) Arvand Haschemi et al. Cell Metabolism
- Induction of M2-like macrophages in recipient NOD-scid mice by allogeneic donor CD4+CD25+ regulatory T cells
- (2012) Xuelian Hu et al. Cellular & Molecular Immunology
- Lipid metabolism in cancer
- (2012) Claudio R. Santos et al. FEBS Journal
- Macrophage polarization and plasticity in health and disease
- (2012) Subhra K. Biswas et al. IMMUNOLOGIC RESEARCH
- The immunosuppressive tumour network: myeloid-derived suppressor cells, regulatory T cells and natural killer T cells
- (2012) Dennis Lindau et al. IMMUNOLOGY
- Clinical Significance of Tumor-Associated Inflammatory Cells in Metastatic Neuroblastoma
- (2012) Shahab Asgharzadeh et al. JOURNAL OF CLINICAL ONCOLOGY
- Pivotal Advance: Arginase-1-independent polyamine production stimulates the expression of IL-4-induced alternatively activated macrophage markers while inhibiting LPS-induced expression of inflammatory genes
- (2012) Jan Van den Bossche et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Mechanisms of triglyceride accumulation in activated macrophages
- (2012) Kenneth R. Feingold et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Omega-3 Polyunsaturated Fatty Acids Antagonize Macrophage Inflammation via Activation of AMPK/SIRT1 Pathway
- (2012) Bingzhong Xue et al. PLoS One
- Prognostic Significance of Tumor-Associated Macrophages in Solid Tumor: A Meta-Analysis of the Literature
- (2012) Qiong-wen Zhang et al. PLoS One
- Origins of tumor-associated macrophages and neutrophils
- (2012) V. Cortez-Retamozo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Alternative Macrophage Activation and Metabolism
- (2011) Justin I. Odegaard et al. Annual Review of Pathology-Mechanisms of Disease
- The mitochondrial citrate carrier: a new player in inflammation
- (2011) Vittoria Infantino et al. BIOCHEMICAL JOURNAL
- Lipid synthesis in macrophages during inflammation in vivo: Effect of agonists of peroxisome proliferator activated receptors α and γ and of retinoid X receptors
- (2011) E. N. Posokhova et al. BIOCHEMISTRY-MOSCOW
- Ferroportin1 deficiency in mouse macrophages impairs iron homeostasis and inflammatory responses
- (2011) Z. Zhang et al. BLOOD
- Tumor-Associated Macrophages Mediate Immunosuppression in the Renal Cancer Microenvironment by Activating the 15-Lipoxygenase-2 Pathway
- (2011) I. Daurkin et al. CANCER RESEARCH
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Linking Lipid Metabolism to the Innate Immune Response in Macrophages through Sterol Regulatory Element Binding Protein-1a
- (2011) Seung-Soon Im et al. Cell Metabolism
- Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation
- (2011) A. R. Grassian et al. GENES & DEVELOPMENT
- Tumor-associated macrophages in breast cancer: distinct subsets, distinct functions
- (2011) Damya Laoui et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY
- Activated CD69+ T Cells Foster Immune Privilege by Regulating IDO Expression in Tumor-Associated Macrophages
- (2011) Q. Zhao et al. JOURNAL OF IMMUNOLOGY
- Regulation of Macrophage Arginase Expression and Tumor Growth by the Ron Receptor Tyrosine Kinase
- (2011) D. R. Sharda et al. JOURNAL OF IMMUNOLOGY
- Obstacles and opportunities for understanding macrophage polarization
- (2011) P. J. Murray et al. JOURNAL OF LEUKOCYTE BIOLOGY
- The Lipogenesis Pathway as a Cancer Target
- (2011) Hanley N. Abramson JOURNAL OF MEDICINAL CHEMISTRY
- Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia
- (2011) Christian M. Metallo et al. NATURE
- Tumor-Associated Macrophages (TAMs) Form an Interconnected Cellular Supportive Network in Anaplastic Thyroid Carcinoma
- (2011) Bernard Caillou et al. PLoS One
- Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of -ketoglutarate to citrate to support cell growth and viability
- (2011) D. R. Wise et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Iron trafficking and metabolism in macrophages: contribution to the polarized phenotype
- (2011) Gaetano Cairo et al. TRENDS IN IMMUNOLOGY
- Infiltration of tumour-associated macrophages in prostate biopsy specimens is predictive of disease progression after hormonal therapy for prostate cancer
- (2010) Norio Nonomura et al. BJU INTERNATIONAL
- Interactions between lymphocytes and myeloid cells regulate pro- versus anti-tumor immunity
- (2010) David G. DeNardo et al. CANCER AND METASTASIS REVIEWS
- Stearoyl-CoA desaturase-1: a novel key player in the mechanisms of cell proliferation, programmed cell death and transformation to cancer
- (2010) R. A. Igal CARCINOGENESIS
- Macrophage Diversity Enhances Tumor Progression and Metastasis
- (2010) Bin-Zhi Qian et al. CELL
- GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects
- (2010) Da Young Oh et al. CELL
- Immunity, Inflammation, and Cancer
- (2010) Sergei I. Grivennikov et al. CELL
- Role of Ferroportin in Macrophage-Mediated Immunity
- (2010) E. E. Johnson et al. INFECTION AND IMMUNITY
- Substrate Fate in Activated Macrophages: A Comparison between Innate, Classic, and Alternative Activation
- (2010) J.-C. Rodriguez-Prados et al. JOURNAL OF IMMUNOLOGY
- A general introduction to the biochemistry of mitochondrial fatty acid β-oxidation
- (2010) Sander Michel Houten et al. JOURNAL OF INHERITED METABOLIC DISEASE
- Induction of fatty acid synthesis is a key requirement for phagocytic differentiation of human monocytes
- (2010) Josef Ecker et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Arginase: an emerging key player in the mammalian immune system
- (2009) Markus Munder BRITISH JOURNAL OF PHARMACOLOGY
- Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability
- (2009) F. Colotta et al. CARCINOGENESIS
- Fatty acids and postprandial inflammation
- (2009) Andrew N Margioris CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
- Differential regulation of iron homeostasis during human macrophage polarized activation
- (2009) Stefania Recalcati et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- PPAR-δ senses and orchestrates clearance of apoptotic cells to promote tolerance
- (2009) Lata Mukundan et al. NATURE MEDICINE
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- Alternative Activation of Macrophages: An Immunologic Functional Perspective
- (2008) Fernando O. Martinez et al. Annual Review of Immunology
- Mammalian Target of Rapamycin and S6 Kinase 1 Positively Regulate 6-thioguanine-Induced Autophagy
- (2008) X. Zeng et al. CANCER RESEARCH
- Adipocyte-Derived Th2 Cytokines and Myeloid PPARδ Regulate Macrophage Polarization and Insulin Sensitivity
- (2008) Kihwa Kang et al. Cell Metabolism
- Alternative M2 Activation of Kupffer Cells by PPARδ Ameliorates Obesity-Induced Insulin Resistance
- (2008) Justin I. Odegaard et al. Cell Metabolism
- Increased density of tumor-associated macrophages is associated with decreased survival in advanced thyroid cancer
- (2008) M. Ryder et al. ENDOCRINE-RELATED CANCER
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