Mesoscale physical principles of collective cell organization

Intermediate filaments and cellular mechanics

(2018) Wolfgang H. Goldmann   CELL BIOLOGY INTERNATIONAL

A geometrically controlled rigidity transition in a model for confluent 3D tissues

(2018) Matthias Merkel et al.   NEW JOURNAL OF PHYSICS

Flocking transitions in confluent tissues

(2018) Fabio Giavazzi et al.   Soft Matter

Collective cell migration without proliferation: density determines cell velocity and wave velocity

(2018) Sham Tlili et al.   Royal Society Open Science

The Solid Mechanics of Cancer and Strategies for Improved Therapy

(2017) Triantafyllos Stylianopoulos   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

Rab GTPases: master regulators that establish the secretory and endocytic pathways

(2017) Suzanne R. Pfeffer   MOLECULAR BIOLOGY OF THE CELL

Topological defects control collective dynamics in neural progenitor cell cultures

(2017) Kyogo Kawaguchi et al.   NATURE

Topological defects in epithelia govern cell death and extrusion

(2017) Thuan Beng Saw et al.   NATURE

A mechanically active heterotypic E-cadherin/N-cadherin adhesion enables fibroblasts to drive cancer cell invasion

(2017) Anna Labernadie et al.   NATURE CELL BIOLOGY

Quantifying forces in cell biology

(2017) Pere Roca-Cusachs et al.   NATURE CELL BIOLOGY

Endocytic reawakening of motility in jammed epithelia

(2017) Chiara Malinverno et al.   NATURE MATERIALS

Long-lived force patterns and deformation waves at repulsive epithelial boundaries

(2017) Pilar Rodríguez-Franco et al.   NATURE MATERIALS

Mechanobiology of collective cell behaviours

(2017) Benoit Ladoux et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Microtubule nucleation: beyond the template

(2017) Johanna Roostalu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Building branched tissue structures: from single cell guidance to coordinated construction

(2017) James W. Spurlin et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Nonlinear Loading-Rate-Dependent Force Response of Individual Vimentin Intermediate Filaments to Applied Strain

(2017) Johanna Block et al.   PHYSICAL REVIEW LETTERS

Three-dimensional forces exerted by leukocytes and vascular endothelial cells dynamically facilitate diapedesis

(2017) Yi-Ting Yeh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emergent cellular self-organization and mechanosensation initiate follicle pattern in the avian skin

(2017) Amy E. Shyer et al.   SCIENCE

Effective viscosity and dynamics of spreading epithelia: a solvable model

(2017) C. Blanch-Mercader et al.   Soft Matter

Force percolation of contractile active gels

(2017) José Alvarado et al.   Soft Matter

Hydrodynamic instabilities, waves and turbulence in spreading epithelia

(2017) C. Blanch-Mercader et al.   Soft Matter

Desmosomes and Intermediate Filaments: Their Consequences for Tissue Mechanics

(2017) Mechthild Hatzfeld et al.   Cold Spring Harbor Perspectives in Biology

Cell-like pressure sensors reveal increase of mechanical stress towards the core of multicellular spheroids under compression

(2017) M. E. Dolega et al.   Nature Communications

A Cell Migration Tracking Tool Supports Coupling of Tissue Rotation to Elongation

(2017) Dong-Yuan Chen et al.   Cell Reports

Convergence of microengineering and cellular self-organization towards functional tissue manufacturing

(2017) Jérémie Laurent et al.   Nature Biomedical Engineering

Single Molecule Force Measurements in Living Cells Reveal a Minimally Tensioned Integrin State

(2016) Alice C. Chang et al.   ACS Nano

Cellular Contraction and Polarization Drive Collective Cellular Motion

(2016) Jacob Notbohm et al.   BIOPHYSICAL JOURNAL

Linking up at the BAR: Oligomerization and F-BAR protein function

(2016) Nathan A. McDonald et al.   CELL CYCLE

On Buckling Morphogenesis

(2016) Celeste M. Nelson   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

Integrin-mediated mechanotransduction

(2016) Zhiqi Sun et al.   JOURNAL OF CELL BIOLOGY

Mechanical regulation of a molecular clutch defines force transmission and transduction in response to matrix rigidity

(2016) Alberto Elosegui-Artola et al.   NATURE CELL BIOLOGY

On the growth and form of cortical convolutions

(2016) Tuomas Tallinen et al.   Nature Physics

Topological defects in confined populations of spindle-shaped cells

(2016) Guillaume Duclos et al.   Nature Physics

Collective pulsatile expansion and swirls in proliferating tumor tissue

(2016) Taeseok Daniel Yang et al.   NEW JOURNAL OF PHYSICS

Emergent structures and dynamics of cell colonies by contact inhibition of locomotion

(2016) Bart Smeets et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Collective cell durotaxis emerges from long-range intercellular force transmission

(2016) R. Sunyer et al.   SCIENCE

Motility-Driven Glass and Jamming Transitions in Biological Tissues

(2016) Dapeng Bi et al.   Physical Review X

Traction force microscopy on soft elastic substrates: A guide to recent computational advances

(2015) Ulrich S. Schwarz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Seeds of Locally Aligned Motion and Stress Coordinate a Collective Cell Migration

(2015) Assaf Zaritsky et al.   BIOPHYSICAL JOURNAL

Collective Cell Motility Promotes Chemotactic Prowess and Resistance to Chemorepulsion

(2015) Gema Malet-Engra et al.   CURRENT BIOLOGY

Tissue mechanics and adhesion during embryo development

(2015) Joseph H. Shawky et al.   DEVELOPMENTAL BIOLOGY

Non-muscle myosin II in disease: mechanisms and therapeutic opportunities

(2015) K. A. Newell-Litwa et al.   Disease Models & Mechanisms

The mechanotransduction machinery at work at adherens junctions

(2015) B. Ladoux et al.   Integrative Biology

Cost-benefit analysis of the mechanisms that enable migrating cells to sustain motility upon changes in matrix environments

(2015) M. Tozluoglu et al.   Journal of the Royal Society Interface

A molecular mechanotransduction pathway regulates collective migration of epithelial cells

(2015) Tamal Das et al.   NATURE CELL BIOLOGY

Force transmission during adhesion-independent migration

(2015) Martin Bergert et al.   NATURE CELL BIOLOGY

Unjamming and cell shape in the asthmatic airway epithelium

(2015) Jin-Ah Park et al.   NATURE MATERIALS

A density-independent rigidity transition in biological tissues

(2015) Dapeng Bi et al.   Nature Physics

Testing the differential adhesion hypothesis across the epithelial−mesenchymal transition

(2015) Steve Pawlizak et al.   NEW JOURNAL OF PHYSICS

Flow and Diffusion in Channel-Guided Cell Migration

(2014) Anna-Kristina Marel et al.   BIOPHYSICAL JOURNAL

Both contractile axial and lateral traction force dynamics drive amoeboid cell motility

(2014) Effie Bastounis et al.   JOURNAL OF CELL BIOLOGY

Interplay of RhoA and mechanical forces in collective cell migration driven by leader cells

(2014) M. Reffay et al.   NATURE CELL BIOLOGY

Rigidity sensing and adaptation through regulation of integrin types

(2014) Alberto Elosegui-Artola et al.   NATURE MATERIALS

Liposome adhesion generates traction stress

(2014) Michael P. Murrell et al.   Nature Physics

Physical influences of the extracellular environment on cell migration

(2014) Guillaume Charras et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The integrin adhesome: from genes and proteins to human disease

(2014) Sabina E. Winograd-Katz et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Dynamic contacts: rearranging adherens junctions to drive epithelial remodelling

(2014) Masatoshi Takeichi   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lattice light-sheet microscopy: Imaging molecules to embryos at high spatiotemporal resolution

(2014) Bi-Chang Chen et al.   SCIENCE

Emergence of collective modes and tri-dimensional structures from epithelial confinement

(2014) M. Deforet et al.   Nature Communications

Long-range ordered vorticity patterns in living tissue induced by cell division

(2014) Ninna S. Rossen et al.   Nature Communications

Epithelial rotation promotes the global alignment of contractile actin bundles during Drosophila egg chamber elongation

(2014) Maureen Cetera et al.   Nature Communications

Matrix geometry determines optimal cancer cell migration strategy and modulates response to interventions

(2013) Melda Tozluoğlu et al.   NATURE CELL BIOLOGY

Quantifying cell-generated mechanical forces within living embryonic tissues

(2013) Otger Campàs et al.   NATURE METHODS

Alignment of cellular motility forces with tissue flow as a mechanism for efficient wound healing

(2013) M. Basan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hydrodynamics of soft active matter

(2013) M. C. Marchetti et al.   REVIEWS OF MODERN PHYSICS

Villification: How the Gut Gets Its Villi

(2013) A. E. Shyer et al.   SCIENCE

A physical sciences network characterization of non-tumorigenic and metastatic cells

(2013)   Scientific Reports

Mammary collective cell migration involves transient loss of epithelial features and individual cell migration within the epithelium

(2012) A. J. Ewald et al.   JOURNAL OF CELL SCIENCE

Collective cell migration: leadership, invasion and segregation

(2012) A. J. Kabla   Journal of the Royal Society Interface

Mechanical waves during tissue expansion

(2012) Xavier Serra-Picamal et al.   Nature Physics

Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors

(2012) T. Stylianopoulos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emerging modes of collective cell migration induced by geometrical constraints

(2012) S. R. K. Vedula et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rotational motion during three-dimensional morphogenesis of mammary epithelial acini relates to laminin matrix assembly

(2012) H. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adhesion Functions in Cell Sorting by Mechanically Coupling the Cortices of Adhering Cells

(2012) J.-L. Maitre et al.   SCIENCE

A Mechanoresponsive Cadherin-Keratin Complex Directs Polarized Protrusive Behavior and Collective Cell Migration

(2011) Gregory F. Weber et al.   DEVELOPMENTAL CELL

Collective cell guidance by cooperative intercellular forces

(2011) Dhananjay T. Tambe et al.   NATURE MATERIALS

Instabilities of Monolayered Epithelia: Shape and Structure of Villi and Crypts

(2011) E. Hannezo et al.   PHYSICAL REVIEW LETTERS

Glass-like dynamics of collective cell migration

(2011) T. E. Angelini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell-ECM traction force modulates endogenous tension at cell-cell contacts

(2011) V. Maruthamuthu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plithotaxis and emergent dynamics in collective cellular migration

(2011) Xavier Trepat et al.   TRENDS IN CELL BIOLOGY

Collective Chemotaxis Requires Contact-Dependent Cell Polarity

(2010) Eric Theveneau et al.   DEVELOPMENTAL CELL

Nanoscale architecture of integrin-based cell adhesions

(2010) Pakorn Kanchanawong et al.   NATURE

α-Catenin as a tension transducer that induces adherens junction development

(2010) Shigenobu Yonemura et al.   NATURE CELL BIOLOGY

Active gels as a description of the actin‐myosin cytoskeleton

(2009) Jean‐François Joanny et al.   HFSP Journal

Mechanosensing in actin stress fibers revealed by a close correlation between force and protein localization

(2009) J. Colombelli et al.   JOURNAL OF CELL SCIENCE

An actomyosin-based barrier inhibits cell mixing at compartmental boundaries in Drosophila embryos

(2009) Bruno Monier et al.   NATURE CELL BIOLOGY

Rab GTPases as coordinators of vesicle traffic

(2009) Harald Stenmark   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Stretching Single Talin Rod Molecules Activates Vinculin Binding

(2009) A. del Rio et al.   SCIENCE

Collective Epithelial Migration and Cell Rearrangements Drive Mammary Branching Morphogenesis

(2008) Andrew J. Ewald et al.   DEVELOPMENTAL CELL

Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesis

(2008) Aron B. Jaffe et al.   JOURNAL OF CELL BIOLOGY

Nature and anisotropy of cortical forces orienting Drosophila tissue morphogenesis

(2008) Matteo Rauzi et al.   NATURE CELL BIOLOGY

From cells to organs: building polarized tissue

(2008) David M. Bryant et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cell Sorting in Three Dimensions: Topology, Fluctuations, and Fluidlike Instabilities

(2008) M. Shane Hutson et al.   PHYSICAL REVIEW LETTERS

Traction Dynamics of Filopodia on Compliant Substrates

(2008) C. E. Chan et al.   SCIENCE

Implications of a poroelastic cytoplasm for the dynamics of animal cell shape

(2008) T.J. Mitchison et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY