Microtubule nucleation: beyond the template

Insights into the Distinct Mechanisms of Action of Taxane and Non-Taxane Microtubule Stabilizers from Cryo-EM Structures

(2017) Elizabeth H. Kellogg et al.   JOURNAL OF MOLECULAR BIOLOGY

Tubulin acetylation protects long-lived microtubules against mechanical ageing

(2017) Didier Portran et al.   NATURE CELL BIOLOGY

Mitotic spindle assembly in animal cells: a fine balancing act

(2017) Suzanna L. Prosser et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Visualizing microtubule structural transitions and interactions with associated proteins

(2016) Eva Nogales et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Patronin/Shot Cortical Foci Assemble the Noncentrosomal Microtubule Array that Specifies the Drosophila Anterior-Posterior Axis

(2016) Dmitry Nashchekin et al.   DEVELOPMENTAL CELL

Molecular Pathway of Microtubule Organization at the Golgi Apparatus

(2016) Jingchao Wu et al.   DEVELOPMENTAL CELL

Five factors can reconstitute all three phases of microtubule polymerization dynamics

(2016) Takashi Moriwaki et al.   JOURNAL OF CELL BIOLOGY

Suppression of microtubule assembly kinetics by the mitotic protein TPX2

(2016) Taylor A. Reid et al.   JOURNAL OF CELL SCIENCE

The size of the EB cap determines instantaneous microtubule stability

(2016) Christian Duellberg et al.   eLife

Microtubule-associated proteins control the kinetics of microtubule nucleation

(2015) Michal Wieczorek et al.   NATURE CELL BIOLOGY

Complementary activities of TPX2 and chTOG constitute an efficient importin-regulated microtubule nucleation module

(2015) Johanna Roostalu et al.   NATURE CELL BIOLOGY

Ring closure activates yeast γTuRC for species-specific microtubule nucleation

(2015) Justin M Kollman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cytoplasmic Nucleation and Atypical Branching Nucleation Generate Endoplasmic Microtubules inPhyscomitrella patens

(2015) Yuki Nakaoka et al.   PLANT CELL

An electron microscopy journey in the study of microtubule structure and dynamics

(2015) Eva Nogales   PROTEIN SCIENCE

Targeting of γ-tubulin complexes to microtubule organizing centers: conservation and divergence

(2015) Tien-chen Lin et al.   TRENDS IN CELL BIOLOGY

Ring closure activates yeast γTuRC for species-specific microtubule nucleation

(2015) Justin M Kollman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

High-Resolution Microtubule Structures Reveal the Structural Transitions in αβ-Tubulin upon GTP Hydrolysis

(2014) Gregory M. Alushin et al.   CELL

Augmin Triggers Microtubule-Dependent Microtubule Nucleation in Interphase Plant Cells

(2014) Ting Liu et al.   CURRENT BIOLOGY

Microtubule Minus-End Stabilization by Polymerization-Driven CAMSAP Deposition

(2014) Kai Jiang et al.   DEVELOPMENTAL CELL

Stu2, the Budding Yeast XMAP215/Dis1 Homolog, Promotes Assembly of Yeast Microtubules by Increasing Growth Rate and Decreasing Catastrophe Frequency

(2014) Marija Podolski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The contribution of αβ-tubulin curvature to microtubule dynamics

(2014) Gary J. Brouhard et al.   JOURNAL OF CELL BIOLOGY

Reconstitution of the augmin complex provides insights into its architecture and function

(2014) Kuo-Chiang Hsia et al.   NATURE CELL BIOLOGY

Microtubule Minus-End Binding Protein CAMSAP2 Controls Axon Specification and Dendrite Development

(2014) Kah Wai Yau et al.   NEURON

Microtubule nucleating and severing enzymes for modifying microtubule array organization and cell morphogenesis in response to environmental cues

(2014) Masayoshi Nakamura   NEW PHYTOLOGIST

Regulation of microtubule minus-end dynamics by CAMSAPs and Patronin

(2014) M. C. Hendershott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A tethered delivery mechanism explains the catalytic action of a microtubule polymerase

(2014) Pelin Ayaz et al.   eLife

Micropattern-Controlled Local Microtubule Nucleation, Transport, and Mesoscale Organization

(2013) Surajit Ghosh et al.   ACS Chemical Biology

Branching Microtubule Nucleation in Xenopus Egg Extracts Mediated by Augmin and TPX2

(2013) Sabine Petry et al.   CELL

A Mechanism for Reorientation of Cortical Microtubule Arrays Driven by Microtubule Severing

(2013) J. J. Lindeboom et al.   SCIENCE

Dynactin Subunit p150Glued Is a Neuron-Specific Anti-Catastrophe Factor

(2013) Jacob E. Lazarus et al.   PLOS BIOLOGY

Estimating the Microtubule GTP Cap Size In Vivo

(2012) Dominique Seetapun et al.   CURRENT BIOLOGY

Microtubule catastrophe and rescue

(2012) Melissa K Gardner et al.   CURRENT OPINION IN CELL BIOLOGY

Reconstitution of dynamic microtubules withDrosophilaXMAP215, EB1, and Sentin

(2012) Wenjing Li et al.   JOURNAL OF CELL BIOLOGY

Conformational changes in tubulin in GMPCPP and GDP-taxol microtubules observed by cryoelectron microscopy

(2012) Hiroaki Yajima et al.   JOURNAL OF CELL BIOLOGY

The where, when and how of microtubule nucleation - one ring to rule them all

(2012) N. Teixido-Travesa et al.   JOURNAL OF CELL SCIENCE

Microtubule-severing enzymes at the cutting edge

(2012) D. J. Sharp et al.   JOURNAL OF CELL SCIENCE

Fission yeast Alp14 is a dose-dependent plus end–tracking microtubule polymerase

(2012) Jawdat Al-Bassam et al.   MOLECULAR BIOLOGY OF THE CELL

An Inducible RNA Interference System inPhyscomitrella patensReveals a Dominant Role of Augmin in Phragmoplast Microtubule Generation

(2012) Yuki Nakaoka et al.   PLANT CELL

The Role of γ-Tubulin in Centrosomal Microtubule Organization

(2012) Eileen O'Toole et al.   PLoS One

Nezha/CAMSAP3 and CAMSAP2 cooperate in epithelial-specific organization of noncentrosomal microtubules

(2012) N. Tanaka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A TOG:  -tubulin Complex Structure Reveals Conformation-Based Mechanisms for a Microtubule Polymerase

(2012) P. Ayaz et al.   SCIENCE

Rapid Microtubule Self-Assembly Kinetics

(2011) Melissa K. Gardner et al.   CELL

Microtubule nucleation by γ-tubulin complexes

(2011) Justin M. Kollman et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Augmin Plays a Critical Role in Organizing the Spindle and Phragmoplast Microtubule Arrays in Arabidopsis

(2011) C.-M. Kimmy Ho et al.   PLANT CELL

XMAP215 polymerase activity is built by combining multiple tubulin-binding TOG domains and a basic lattice-binding region

(2011) P. O. Widlund et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GTP S microtubules mimic the growing microtubule end structure recognized by end-binding proteins (EBs)

(2011) S. P. Maurer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of microtubule dynamics by TOG-domain proteins XMAP215/Dis1 and CLASP

(2011) Jawdat Al-Bassam et al.   TRENDS IN CELL BIOLOGY

Patronin Regulates the Microtubule Network by Protecting Microtubule Minus Ends

(2010) Sarah S. Goodwin et al.   CELL

CLASP Promotes Microtubule Rescue by Recruiting Tubulin Dimers to the Microtubule

(2010) Jawdat Al-Bassam et al.   DEVELOPMENTAL CELL

Kinetochores Generate Microtubules with Distal Plus Ends: Their Roles and Limited Lifetime in Mitosis

(2010) Etsushi Kitamura et al.   DEVELOPMENTAL CELL

CDK5RAP2 stimulates microtubule nucleation by the γ-tubulin ring complex

(2010) Yuk-Kwan Choi et al.   JOURNAL OF CELL BIOLOGY

Microtubule nucleating γ-TuSC assembles structures with 13-fold microtubule-like symmetry

(2010) Justin M. Kollman et al.   NATURE

Structural Basis of Interprotofilament Interaction and Lateral Deformation of Microtubules

(2010) Haixin Sui et al.   STRUCTURE

Lattice Structure of Cytoplasmic Microtubules in a Cultured Mammalian Cell

(2009) J. Richard McIntosh et al.   JOURNAL OF MOLECULAR BIOLOGY

Functional Overlap of Microtubule Assembly Factors in Chromatin-Promoted Spindle Assembly

(2009) Aaron C. Groen et al.   MOLECULAR BIOLOGY OF THE CELL

XMAP215–EB1 Interaction Is Required for Proper Spindle Assembly and Chromosome Segregation in Xenopus Egg Extract

(2009) Iva Kronja et al.   MOLECULAR BIOLOGY OF THE CELL

XMAP215 Is a Processive Microtubule Polymerase

(2008) Gary J. Brouhard et al.   CELL

Augmin: a protein complex required for centrosome-independent microtubule generation within the spindle

(2008) Gohta Goshima et al.   JOURNAL OF CELL BIOLOGY

A Multicomponent Assembly Pathway Contributes to the Formation of Acentrosomal Microtubule Arrays in Interphase Drosophila Cells

(2008) Gregory C. Rogers et al.   MOLECULAR BIOLOGY OF THE CELL

Structural basis of microtubule severing by the hereditary spastic paraplegia protein spastin

(2008) Antonina Roll-Mecak et al.   NATURE

Meiotic Regulation of TPX2 Protein Levels Governs Cell Cycle Progression in Mouse Oocytes

(2008) Stéphane Brunet et al.   PLoS One

Tubulin Dimers Oligomerize before Their Incorporation into Microtubules

(2008) Julien Mozziconacci et al.   PLoS One