Rigidity sensing and adaptation through regulation of integrin types

Contractile Fibers and Catch-Bond Clusters: a Biological Force Sensor?

(2013) Elizaveta A. Novikova et al.   BIOPHYSICAL JOURNAL

Determinants of Maximal Force Transmission in a Motor-Clutch Model of Cell Traction in a Compliant Microenvironment

(2013) Benjamin L. Bangasser et al.   BIOPHYSICAL JOURNAL

Altered Microenvironment Promotes Progression of Preinvasive Breast Cancer: Myoepithelial Expression of  v 6 Integrin in DCIS Identifies High-risk Patients and Predicts Recurrence

(2013) M. D. Allen et al.   CLINICAL CANCER RESEARCH

β1- and αv-class integrins cooperate to regulate myosin II during rigidity sensing of fibronectin-based microenvironments

(2013) Herbert B. Schiller et al.   NATURE CELL BIOLOGY

Integrin-dependent force transmission to the extracellular matrix by  -actinin triggers adhesion maturation

(2013) P. Roca-Cusachs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Force Fluctuations within Focal Adhesions Mediate ECM-Rigidity Sensing to Guide Directed Cell Migration

(2012) Sergey V. Plotnikov et al.   CELL

Resolving Two-dimensional Kinetics of the Integrin αIIbβ3-Fibrinogen Interactions Using Binding-Unbinding Correlation Spectroscopy

(2012) Rustem I. Litvinov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Finding the weakest link – exploring integrin-mediated mechanical molecular pathways

(2012) Pere Roca-Cusachs et al.   JOURNAL OF CELL SCIENCE

The nanomechanical signature of breast cancer

(2012) Marija Plodinec et al.   Nature Nanotechnology

Mechanical waves during tissue expansion

(2012) Xavier Serra-Picamal et al.   Nature Physics

Cells test substrate rigidity by local contractions on submicrometer pillars

(2012) S. Ghassemi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence of a large-scale mechanosensing mechanism for cellular adaptation to substrate stiffness

(2012) L. Trichet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of loading conditions on the dissociation behaviour of catch bond clusters

(2011) L. Sun et al.   Journal of the Royal Society Interface

Harnessing traction-mediated manipulation of the cell/matrix interface to control stem-cell fate

(2010) Nathaniel Huebsch et al.   NATURE MATERIALS

Demonstration of catch bonds between an integrin and its ligand

(2009) Fang Kong et al.   JOURNAL OF CELL BIOLOGY

Clustering of  5 1 integrins determines adhesion strength whereas  v 3 and talin enable mechanotransduction

(2009) P. Roca-Cusachs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Micropatterning of Single Endothelial Cell Shape Reveals a Tight Coupling between Nuclear Volume in G1 and Proliferation

(2008) Pere Roca-Cusachs et al.   BIOPHYSICAL JOURNAL

Traction stress in focal adhesions correlates biphasically with actin retrograde flow speed

(2008) Margaret L. Gardel et al.   JOURNAL OF CELL BIOLOGY

Traction Dynamics of Filopodia on Compliant Substrates

(2008) C. E. Chan et al.   SCIENCE