The Cellular Environment Guides Self‐Assembly and Structural Conformations of Microtubule‐Associated Protein Tau (MAPT)
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Title
The Cellular Environment Guides Self‐Assembly and Structural Conformations of Microtubule‐Associated Protein Tau (MAPT)
Authors
Keywords
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Journal
ISRAEL JOURNAL OF CHEMISTRY
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2023-10-12
DOI
10.1002/ijch.202300104
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Note: Only part of the references are listed.- Fibril treatment changes protein interactions of tau and α-synuclein in human neurons
- (2023) Tagan A. Griffin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Chemical Features of Polyanions Modulate Tau Aggregation and Conformational States
- (2023) Kelly M. Montgomery et al. Journal of the American Chemical Society
- Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration
- (2022) Tara E. Tracy et al. CELL
- Tau modification by the norepinephrine metabolite DOPEGAL stimulates its pathology and propagation
- (2022) Seong Su Kang et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Macromolecular Structures and Proteins Interacting with the Microtubule Associated Tau Protein
- (2022) Juan S. Jiménez NEUROSCIENCE
- Cryo-EM structure of RNA-induced tau fibrils reveals a small C-terminal core that may nucleate fibril formation
- (2022) Romany Abskharon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Stress routes clients to the proteasome via a BAG2 ubiquitin-independent degradation condensate
- (2022) Daniel C. Carrettiero et al. Nature Communications
- Assembly of recombinant tau into filaments identical to those of Alzheimer’s disease and chronic traumatic encephalopathy
- (2022) Sofia Lövestam et al. eLife
- In vitro Tau Aggregation Inducer Molecules Influence the Effects of MAPT Mutations on Aggregation Dynamics
- (2022) David J. Ingham et al. BIOCHEMISTRY
- RNA induces unique tau strains and stabilizes Alzheimer’s disease seeds
- (2022) Amy N. Zwierzchowski-Zarate et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hsp multichaperone complex buffers pathologically modified Tau
- (2022) Antonia Moll et al. Nature Communications
- Microtubule lattice spacing governs cohesive envelope formation of tau family proteins
- (2022) Valerie Siahaan et al. Nature Chemical Biology
- Hierarchical chemical determination of amyloid polymorphs in neurodegenerative disease
- (2021) Dan Li et al. Nature Chemical Biology
- Tau Post-translational Modifications: Dynamic Transformers of Tau Function, Degradation, and Aggregation
- (2021) Carolina Alquezar et al. Frontiers in Neurology
- Small heat shock protein 22kDa can modulate the aggregation and liquid‐liquid phase separation behavior of Tau
- (2021) April L. Darling et al. PROTEIN SCIENCE
- Tau: Enabler of diverse brain disorders and target of rapidly evolving therapeutic strategies
- (2021) Che-Wei Chang et al. SCIENCE
- Arrayed CRISPR reveals genetic regulators of tau aggregation, autophagy and mitochondria in Alzheimer’s disease model
- (2021) Lishu Duan et al. Scientific Reports
- Tau strains shape disease
- (2021) Jaime Vaquer-Alicea et al. ACTA NEUROPATHOLOGICA
- Tau aggregates are RNA-protein assemblies that mislocalize multiple nuclear speckle components
- (2021) Evan Lester et al. NEURON
- Tau forms oligomeric complexes on microtubules that are distinct from tau aggregates
- (2021) Melina Theoni Gyparaki et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Liquid–liquid phase separation of Tau by self and complex coacervation
- (2021) Saeed Najafi et al. PROTEIN SCIENCE
- Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice
- (2021) Benjamin Caballero et al. Nature Communications
- The Sulfation Code of Tauopathies: Heparan Sulfate Proteoglycans in the Prion Like Spread of Tau Pathology
- (2021) Dylan Mah et al. Frontiers in Molecular Biosciences
- Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy
- (2021) Lulu Jiang et al. MOLECULAR CELL
- “Don’t Phos Over Tau”: recent developments in clinical biomarkers and therapies targeting tau phosphorylation in Alzheimer’s disease and other tauopathies
- (2021) Yuxing Xia et al. Molecular Neurodegeneration
- Cellular and pathological heterogeneity of primary tauopathies
- (2021) Dah-eun Chloe Chung et al. Molecular Neurodegeneration
- The extracellular chaperone Clusterin enhances Tau aggregate seeding in a cellular model
- (2021) Patricia Yuste-Checa et al. Nature Communications
- Genome-wide CRISPR screen identifies protein pathways modulating tau protein levels in neurons
- (2021) Carlos G. Sanchez et al. Communications Biology
- Splicing machinery is impaired in rheumatoid arthritis, associated with disease activity and modulated by anti-TNF therapy
- (2021) Alejandro Ibáñez-Costa et al. ANNALS OF THE RHEUMATIC DISEASES
- Charge neutralization of lysine via carbamylation reveals hidden aggregation hot‐spots in tau protein flanking regions
- (2021) Joshna Gadhavi et al. FEBS Journal
- Flipping the switch: How cysteine oxidation directs tau amyloid conformations
- (2021) Danny M. Hatters JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural mapping techniques distinguish the surfaces of fibrillar 1N3R and 1N4R human tau
- (2021) Emilie Caroux et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Human Tau Isoforms and Proteolysis for Production of Toxic Tau Fragments in Neurodegeneration
- (2021) Ben Boyarko et al. Frontiers in Neuroscience
- In vivo rate-determining steps of tau seed accumulation in Alzheimer’s disease
- (2021) Georg Meisl et al. Science Advances
- Targeting Chondroitin Sulfate Proteoglycans: An Emerging Therapeutic Strategy to Treat CNS Injury
- (2020) Nabanita Mukherjee et al. ACS Chemical Neuroscience
- Exploring the interplay between fibrillization and amorphous aggregation channels on the energy landscapes of tau repeat isoforms
- (2020) Xun Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- LRP1 is a master regulator of tau uptake and spread
- (2020) Jennifer N. Rauch et al. NATURE
- A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer’s disease
- (2020) Nicolas R. Barthélemy et al. NATURE MEDICINE
- Mechanisms of Heparin-Induced Tau Aggregation Revealed by a Single Nanopore
- (2020) Nicoletta Giamblanco et al. ACS Sensors
- Tau-mediated dysregulation of RNA: Evidence for a common molecular mechanism of toxicity in frontotemporal dementia and other tauopathies
- (2020) Shon A. Koren et al. NEUROBIOLOGY OF DISEASE
- Liquid-liquid phase separation induces pathogenic tau conformations in vitro
- (2020) Nicholas M. Kanaan et al. Nature Communications
- Lipid membrane templated misfolding and self-assembly of intrinsically disordered tau protein
- (2020) Jaroslaw Majewski et al. Scientific Reports
- Aggregation Kinetics and Filament Structure of a Tau Fragment Are Influenced by the Sulfation Pattern of the Cofactor Heparin
- (2020) David Townsend et al. BIOCHEMISTRY
- Phosphorylated tau interactome in the human Alzheimer’s disease brain
- (2020) Eleanor Drummond et al. BRAIN
- Cryo-EM structures of tau filaments
- (2020) Sjors HW Scheres et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Tau PTM Profiles Identify Patient Heterogeneity and Stages of Alzheimer’s Disease
- (2020) Hendrik Wesseling et al. CELL
- The two Cysteines of Tau protein are functionally distinct and contribute differentially to its pathogenicity in vivo
- (2020) Engie Prifti et al. JOURNAL OF NEUROSCIENCE
- Liquid-liquid phase separation of tau protein: The crucial role of electrostatic interactions
- (2019) Solomiia Boyko et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Polyphosphate initiates tau aggregation through intra- and intermolecular scaffolding
- (2019) Sanjula P. Wickramasinghe et al. BIOPHYSICAL JOURNAL
- In vitro 0N4R tau fibrils contain a monomorphic β-sheet core enclosed by dynamically heterogeneous fuzzy coat segments
- (2019) Aurelio J. Dregni et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tau local structure shields an amyloid-forming motif and controls aggregation propensity
- (2019) Dailu Chen et al. Nature Communications
- Evidence of corticofugal tau spreading in patients with frontotemporal dementia
- (2019) Eun-Joo Kim et al. ACTA NEUROPATHOLOGICA
- Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis
- (2019) Peter Dongmin Sohn et al. NEURON
- Compromised function of the ESCRT pathway promotes endolysosomal escape of tau seeds and propagation of tau aggregation
- (2019) John J. Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Impaired tau–microtubule interactions are prevalent among pathogenic tau variants arising from missense mutations
- (2019) Yuxing Xia et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Site-Specific Hyperphosphorylation Inhibits, Rather than Promotes, Tau Fibrillization, Seeding Capacity, and Its Microtubule Binding
- (2019) Mahmood Haj-Yahya et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Protein–Protein Interactions in the Molecular Chaperone Network
- (2018) Rebecca Freilich et al. ACCOUNTS OF CHEMICAL RESEARCH
- Hsp70 Inhibits the Nucleation and Elongation of Tau and Sequesters Tau Aggregates with High Affinity
- (2018) Franziska Kundel et al. ACS Chemical Biology
- Oligomer Diversity during the Aggregation of the Repeat Region of Tau
- (2018) Magnus Kjaergaard et al. ACS Chemical Neuroscience
- Blocking the Thiol at Cysteine-322 Destabilizes Tau Protein and Prevents Its Oligomer Formation
- (2018) Hui Chen et al. ACS Chemical Neuroscience
- The Binding Mode of a Tau Peptide with Tubulin
- (2018) Harindranath Kadavath et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Amyloid Polymorphism in the Protein Folding and Aggregation Energy Landscape
- (2018) Jozef Adamcik et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Tau localises within mitochondrial sub-compartments and its caspase cleavage affects ER-mitochondria interactions and cellular Ca 2+ handling
- (2018) Domenico Cieri et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Tau protein liquid–liquid phase separation can initiate tau aggregation
- (2018) Susanne Wegmann et al. EMBO JOURNAL
- Tau Proteolysis in the Pathogenesis of Tauopathies: Neurotoxic Fragments and Novel Biomarkers
- (2018) James P. Quinn et al. JOURNAL OF ALZHEIMERS DISEASE
- Distinct differences in prion-like seeding and aggregation between Tau protein variants provide mechanistic insights into tauopathies.
- (2018) Kevin H. Strang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Specific glycosaminoglycan chain length and sulfation patterns are required for cell uptake of tauversusα-synuclein and β-amyloid aggregates
- (2018) Barbara E. Stopschinski et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Protein Semisynthesis Provides Access to Tau Disease-Associated Post-translational Modifications (PTMs) and Paves the Way to Deciphering the Tau PTM Code in Health and Diseased States
- (2018) Mahmood Haj-Yahya et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Mapping interactions with the chaperone network reveals factors that protect against tau aggregation
- (2018) Sue-Ann Mok et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Near-atomic model of microtubule-tau interactions
- (2018) Elizabeth H. Kellogg et al. SCIENCE
- Mapping interactions with the chaperone network reveals factors that protect against tau aggregation
- (2018) Sue-Ann Mok et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Inert and seed-competent tau monomers suggest structural origins of aggregation
- (2018) Hilda Mirbaha et al. eLife
- The molecular language of membraneless organelles
- (2018) Edward Gomes et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Tau filaments from multiple cases of sporadic and inherited Alzheimer’s disease adopt a common fold
- (2018) Benjamin Falcon et al. ACTA NEUROPATHOLOGICA
- Inorganic polyphosphate, a multifunctional polyanionic protein scaffold
- (2018) Lihan Xie et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cofactors are essential constituents of stable and seeding-active tau fibrils
- (2018) Yann Fichou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cryo-EM structures of tau filaments from Alzheimer’s disease
- (2017) Anthony W. P. Fitzpatrick et al. NATURE
- A Brief Overview of Tauopathy: Causes, Consequences, and Therapeutic Strategies
- (2017) Miranda E. Orr et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Extracellular Tau and Its Potential Role in the Propagation of Tau Pathology
- (2017) Kaoru Yamada Frontiers in Neuroscience
- Using chirality to probe the conformational dynamics and assembly of intrinsically disordered amyloid proteins
- (2017) Jevgenij A. Raskatov et al. Scientific Reports
- FLEXITau: Quantifying Post-translational Modifications of Tau Protein in Vitro and in Human Disease
- (2016) Waltraud Mair et al. ANALYTICAL CHEMISTRY
- Primary Fibril Nucleation of Aggregation Prone Tau Fragments PHF6 and PHF6*
- (2016) Florent X. Smit et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Polyphosphate: A Conserved Modifier of Amyloidogenic Processes
- (2016) Claudia M. Cremers et al. MOLECULAR CELL
- Remodeling of the conformational ensemble of the repeat domain of tau by an aggregation enhancer
- (2016) Elias Akoury et al. PROTEIN SCIENCE
- Autophagic and lysosomal defects in human tauopathies: analysis of post-mortem brain from patients with familial Alzheimer disease, corticobasal degeneration and progressive supranuclear palsy
- (2016) Antonio Piras et al. Acta Neuropathologica Communications
- RNA Binds to Tau Fibrils and Sustains Template-Assisted Growth
- (2015) Paul D. Dinkel et al. BIOCHEMISTRY
- Cellular factors modulating the mechanism of tau protein aggregation
- (2015) Sarah N. Fontaine et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Tau Aggregation Propensity Engrained in Its Solution State
- (2015) Neil A. Eschmann et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Tau post-translational modifications in wild-type and human amyloid precursor protein transgenic mice
- (2015) Meaghan Morris et al. NATURE NEUROSCIENCE
- Structural Impact of Tau Phosphorylation at Threonine 231
- (2015) Martin Schwalbe et al. STRUCTURE
- A mechanistic model of tau amyloid aggregation based on direct observation of oligomers
- (2015) Sarah L. Shammas et al. Nature Communications
- Lysine methylation is an endogenous post-translational modification of tau protein in human brain and a modulator of aggregation propensity
- (2014) Kristen E. Funk et al. BIOCHEMICAL JOURNAL
- Distinct Tau Prion Strains Propagate in Cells and Mice and Define Different Tauopathies
- (2014) David W. Sanders et al. NEURON
- Inorganic polyphosphate regulates neuronal excitability through modulation of voltage-gated channels
- (2014) Stephanie C Stotz et al. Molecular Brain
- Signalling properties of inorganic polyphosphate in the mammalian brain
- (2013) Kira M. Holmström et al. Nature Communications
- Analysis of the Tau-Associated Proteome Reveals That Exchange of Hsp70 for Hsp90 Is Involved in Tau Degradation
- (2012) Andrea D. Thompson et al. ACS Chemical Biology
- FTDP-17 Tau Mutations Induce Distinct Effects on Aggregation and Microtubule Interactions
- (2012) Benjamin Combs et al. BIOCHEMISTRY
- Imbalance of Hsp70 family variants fosters tau accumulation
- (2012) Umesh K. Jinwal et al. FASEB JOURNAL
- Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases
- (2012) Giovanni Coppola et al. HUMAN MOLECULAR GENETICS
- Tau Isoform Composition Influences Rate and Extent of Filament Formation
- (2012) Qi Zhong et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Oligomeric Intermediates in Amyloid Formation: Structure Determination and Mechanisms of Toxicity
- (2012) Marcus Fändrich JOURNAL OF MOLECULAR BIOLOGY
- Identification of an Aggregation-Prone Structure of Tau
- (2012) Shana Elbaum-Garfinkle et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Heat Shock Protein 70 Prevents both Tau Aggregation and the Inhibitory Effects of Preexisting Tau Aggregates on Fast Axonal Transport
- (2011) Kristina R. Patterson et al. BIOCHEMISTRY
- Competing Interactions Stabilize Pro- and Anti-aggregant Conformations of Human Tau
- (2011) Susanne Wegmann et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cyclic AMP-dependent Protein Kinase Regulates the Alternative Splicing of Tau Exon 10
- (2011) Jianhua Shi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Diversity of Assembly Mechanisms of a Generic Amyloid Fold
- (2011) Timo Eichner et al. MOLECULAR CELL
- Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice
- (2011) Cristian A Lasagna-Reeves et al. Molecular Neurodegeneration
- Heparan Sulfate Proteoglycans
- (2011) S. Sarrazin et al. Cold Spring Harbor Perspectives in Biology
- The Role of the Lipid Bilayer in Tau Aggregation
- (2010) Shana Elbaum-Garfinkle et al. BIOPHYSICAL JOURNAL
- Hsc70 Rapidly Engages Tau after Microtubule Destabilization
- (2010) Umesh K. Jinwal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Quantitative Determination of the Conformational Properties of Partially Folded and Intrinsically Disordered Proteins Using NMR Dipolar Couplings
- (2009) Malene Ringkjøbing Jensen et al. STRUCTURE
- Structural Classification of Toxic Amyloid Oligomers
- (2008) Charles G. Glabe JOURNAL OF BIOLOGICAL CHEMISTRY
- Tau Mutations in Neurodegenerative Diseases
- (2008) Michael S. Wolfe JOURNAL OF BIOLOGICAL CHEMISTRY
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