A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer’s disease

Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-β in iPSC-Derived Alzheimer’s Disease Neurons

(2019) Rik van der Kant et al.   Cell Stem Cell

Tau PET in autosomal dominant Alzheimer’s disease: relationship with cognition, dementia and other biomarkers

(2019) Brian A Gordon et al.   BRAIN

Predicting diagnosis and cognition with 18F-AV-1451 tau PET and structural MRI in Alzheimer's disease

(2019) Niklas Mattsson et al.   Alzheimers & Dementia

Emerging cerebrospinal fluid biomarkers in autosomal dominant Alzheimer's disease

(2019) Suzanne E. Schindler et al.   Alzheimers & Dementia

The bivariate distribution of amyloid-β and tau: relationship with established neurocognitive clinical syndromes

(2019) Clifford R Jack et al.   BRAIN

Early striatal amyloid deposition distinguishes Down syndrome and autosomal dominant Alzheimer's disease from late-onset amyloid deposition

(2018) Ann D. Cohen et al.   Alzheimers & Dementia

NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease

(2018) Clifford R. Jack et al.   Alzheimers & Dementia

Spatial patterns of neuroimaging biomarker change in individuals from families with autosomal dominant Alzheimer's disease: a longitudinal study

(2018) Brian A Gordon et al.   LANCET NEUROLOGY

Tau Kinetics in Neurons and the Human Central Nervous System

(2018) Chihiro Sato et al.   NEURON

Association Between Amyloid and Tau Accumulation in Young Adults With Autosomal Dominant Alzheimer Disease

(2018) Yakeel T. Quiroz et al.   JAMA Neurology

Phospho-Tau Bar Code: Analysis of Phosphoisotypes of Tau and Its Application to Tauopathy

(2018) Taeko Kimura et al.   Frontiers in Neuroscience

Longitudinal cognitive and biomarker changes in dominantly inherited Alzheimer disease

(2018) Eric McDade et al.   NEUROLOGY

Cryo-EM structures of tau filaments from Alzheimer’s disease

(2017) Anthony W. P. Fitzpatrick et al.   NATURE

Amyloid-β plaques enhance Alzheimer's brain tau-seeded pathologies by facilitating neuritic plaque tau aggregation

(2017) Zhuohao He et al.   NATURE MEDICINE

Associations between [18F]AV1451 tau PET and CSF measures of tau pathology in a clinical sample

(2017) Renaud La Joie et al.   NEUROLOGY

Anti-tau antibody administration increases plasma tau in transgenic mice and patients with tauopathy

(2017) Kiran Yanamandra et al.   Science Translational Medicine

Neurofibrillary Tangle Stage and the Rate of Progression of Alzheimer Symptoms

(2017) Jing Qian et al.   JAMA Neurology

BDNFVal66Met moderates memory impairment, hippocampal function and tau in preclinical autosomal dominant Alzheimer’s disease

(2016) Yen Ying Lim et al.   BRAIN

Tau Protein Quantification in Human Cerebrospinal Fluid by Targeted Mass Spectrometry at High Sequence Coverage Provides Insights into Its Primary Structure Heterogeneity

(2016) Nicolas R Barthélemy et al.   JOURNAL OF PROTEOME RESEARCH

Longitudinal relationships among biomarkers for Alzheimer disease in the Adult Children Study

(2016) Chengjie Xiong et al.   NEUROLOGY

A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers

(2016) Clifford R. Jack et al.   NEUROLOGY

Site-specific phosphorylation of tau inhibits amyloid-β toxicity in Alzheimer’s mice

(2016) Arne Ittner et al.   SCIENCE

Tau positron emission tomographic imaging in aging and early Alzheimer disease

(2015) Keith A. Johnson et al.   ANNALS OF NEUROLOGY

Age and amyloid effects on human central nervous system amyloid-beta kinetics

(2015) Bruce W. Patterson et al.   ANNALS OF NEUROLOGY

Bivariate correlation coefficients in family-type clustered studies

(2015) Jingqin Luo et al.   BIOMETRICAL JOURNAL

Further understanding of tau phosphorylation: implications for therapy

(2015) Miguel Medina et al.   Expert Review of Neurotherapeutics

Partial volume correction in quantitative amyloid imaging

(2015) Yi Su et al.   NEUROIMAGE

Further understanding of tau phosphorylation: implications for therapy

(2015) Miguel Medina et al.   Expert Review of Neurotherapeutics

Associations Between Biomarkers and Age in the Presenilin 1 E280A Autosomal Dominant Alzheimer Disease Kindred

(2015) Adam S. Fleisher et al.   JAMA Neurology

Symptom onset in autosomal dominant Alzheimer disease: A systematic review and meta-analysis

(2014) D. C. Ryman et al.   NEUROLOGY

Longitudinal Change in CSF Biomarkers in Autosomal-Dominant Alzheimer's Disease

(2014) A. M. Fagan et al.   Science Translational Medicine

Longitudinal change in CSF Tau and Aβ biomarkers for up to 48 months in ADNI

(2013) Jon B. Toledo et al.   ACTA NEUROPATHOLOGICA

Reduced CSF p-Tau181 to Tau ratio is a biomarker for FTLD-TDP

(2013) W. T. Hu et al.   NEUROLOGY

Clinical and psychological characteristics of the initial cohort of the Dominantly Inherited Alzheimer Network (DIAN).

(2013) Martha Storandt et al.   NEUROPSYCHOLOGY

Regional variability of imaging biomarkers in autosomal dominant Alzheimer's disease

(2013) T. L. S. Benzinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased in Vivo Amyloid- 42 Production, Exchange, and Loss in Presenilin Mutation Carriers

(2013) R. Potter et al.   Science Translational Medicine

Recommendations to standardize preanalytical confounding factors in Alzheimer’s and Parkinson’s disease cerebrospinal fluid biomarkers: an update

(2012) Marta del Campo et al.   Biomarkers in Medicine

Cortical atrophy in presymptomatic Alzheimer's disease presenilin 1 mutation carriers

(2012) Y. T. Quiroz et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease

(2012) Randall J. Bateman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cerebrospinal Fluid Profiles and Prospective Course and Outcome in Patients With Amnestic Mild Cognitive Impairment

(2011) Ozioma C. Okonkwo   ARCHIVES OF NEUROLOGY

Exosome-associated Tau Is Secreted in Tauopathy Models and Is Selectively Phosphorylated in Cerebrospinal Fluid in Early Alzheimer Disease

(2011) Sudad Saman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In Vivo Microdialysis Reveals Age-Dependent Decrease of Brain Interstitial Fluid Tau Levels in P301S Human Tau Transgenic Mice

(2011) K. Yamada et al.   JOURNAL OF NEUROSCIENCE

Soluble amyloid  -protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration

(2011) M. Jin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

(2010) Lars M. Ittner et al.   CELL

A  Oligomers Cause Localized Ca2+ Elevation, Missorting of Endogenous Tau into Dendrites, Tau Phosphorylation, and Destruction of Microtubules and Spines

(2010) H. Zempel et al.   JOURNAL OF NEUROSCIENCE