The extracellular chaperone Clusterin enhances Tau aggregate seeding in a cellular model
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The extracellular chaperone Clusterin enhances Tau aggregate seeding in a cellular model
Authors
Keywords
-
Journal
Nature Communications
Volume 12, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-08-11
DOI
10.1038/s41467-021-25060-1
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Apolipoprotein E4 Reduction with Antisense Oligonucleotides Decreases Neurodegeneration in a Tauopathy Model
- (2021) Alexandra Litvinchuk et al. ANNALS OF NEUROLOGY
- Synergistic Effects of APOE and CLU May Increase the Risk of Alzheimer’s Disease: Acceleration of Atrophy in the Volumes and Shapes of the Hippocampus and Amygdala
- (2021) Na An et al. JOURNAL OF ALZHEIMERS DISEASE
- Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia
- (2021) Chao Wang et al. NEURON
- In situ architecture of neuronal α-Synuclein inclusions
- (2021) Victoria A. Trinkaus et al. Nature Communications
- Heparan sulfate is a clearance receptor for aberrant extracellular proteins
- (2020) Eisuke Itakura et al. JOURNAL OF CELL BIOLOGY
- Bacterial Hsp70 resolves misfolded states and accelerates productive folding of a multi-domain protein
- (2020) Rahmi Imamoglu et al. Nature Communications
- Disassembly of Tau fibrils by the human Hsp70 disaggregation machinery generates small seeding-competent species
- (2020) Eliana Nachman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Protein transmission in neurodegenerative disease
- (2020) Chao Peng et al. Nature Reviews Neurology
- Tau molecular diversity contributes to clinical heterogeneity in Alzheimer’s disease
- (2020) Simon Dujardin et al. NATURE MEDICINE
- Cryo-EM structures of tau filaments
- (2020) Sjors HW Scheres et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Extracellular clusterin limits the uptake of α‐synuclein fibrils by murine and human astrocytes
- (2020) Alice Filippini et al. GLIA
- The Down-Regulation of Clusterin Expression Enhances the αSynuclein Aggregation Process
- (2020) Chiara Lenzi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Secreted Chaperones in Neurodegeneration
- (2020) Kriti Chaplot et al. Frontiers in Aging Neuroscience
- Clusterin ameliorates tau pathology in vivo by inhibiting fibril formation
- (2020) Aleksandra M. Wojtas et al. Acta Neuropathologica Communications
- Clusterin in Alzheimer’s Disease: Mechanisms, Genetics, and Lessons From Other Pathologies
- (2019) Evangeline M. Foster et al. Frontiers in Neuroscience
- Progressive parkinsonism in older adults is related to the burden of mixed brain pathologies
- (2019) Aron S. Buchman et al. NEUROLOGY
- Propagation of Protein Aggregation in Neurodegenerative Diseases
- (2019) Jaime Vaquer-Alicea et al. Annual Review of Biochemistry
- Mechanisms of secretion and spreading of pathological tau protein
- (2019) Cecilia A. Brunello et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Compromised function of the ESCRT pathway promotes endolysosomal escape of tau seeds and propagation of tau aggregation
- (2019) John J. Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer’s Disease
- (2019) Yi-Chen Hsieh et al. Cell Reports
- Differential effects of apoE and apoJ mimetic peptides on the action of an anti-Aβ scFv in 3xTg-AD mice
- (2018) Laia Montoliu-Gaya et al. BIOCHEMICAL PHARMACOLOGY
- Intraventricular infusion of clusterin ameliorated cognition and pathology in Tg6799 model of Alzheimer’s disease
- (2018) Xue-Mei Qi et al. BMC NEUROSCIENCE
- Mapping interactions with the chaperone network reveals factors that protect against tau aggregation
- (2018) Sue-Ann Mok et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Mapping interactions with the chaperone network reveals factors that protect against tau aggregation
- (2018) Sue-Ann Mok et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Single-Molecule Characterization of the Interactions between Extracellular Chaperones and Toxic α-Synuclein Oligomers
- (2018) Daniel R. Whiten et al. Cell Reports
- Propagation and spread of pathogenic protein assemblies in neurodegenerative diseases
- (2018) Mathias Jucker et al. NATURE NEUROSCIENCE
- A new era for understanding amyloid structures and disease
- (2018) Matthew G. Iadanza et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Tau Internalization is Regulated by 6-O Sulfation on Heparan Sulfate Proteoglycans (HSPGs)
- (2018) Jennifer N. Rauch et al. Scientific Reports
- Clusterin Is Required for β-Amyloid Toxicity in Human iPSC-Derived Neurons
- (2018) Jacqueline P. Robbins et al. Frontiers in Neuroscience
- Clusterin contributes to early stage of Alzheimer's disease pathogenesis
- (2018) Shin-Bi Oh et al. BRAIN PATHOLOGY
- APOE ε2 is associated with increased tau pathology in primary tauopathy
- (2018) Na Zhao et al. Nature Communications
- Galectin-8–mediated selective autophagy protects against seeded tau aggregation
- (2017) Benjamin Falcon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The release and trans-synaptic transmission of Tau via exosomes
- (2017) Yipeng Wang et al. Molecular Neurodegeneration
- ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy
- (2017) Yang Shi et al. NATURE
- Loss of clusterin shifts amyloid deposition to the cerebrovasculature via disruption of perivascular drainage pathways
- (2017) Aleksandra M. Wojtas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Prion Properties of SOD1 in Amyotrophic Lateral Sclerosis and Potential Therapy
- (2017) Caroline Sibilla et al. Cold Spring Harbor Perspectives in Biology
- Clusterin protects neurons against intracellular proteotoxicity
- (2017) Jenna M. Gregory et al. Acta Neuropathologica Communications
- Characterization of ApoJ-reconstituted high-density lipoprotein (rHDL) nanodisc for the potential treatment of cerebral β-amyloidosis
- (2017) Sofía Fernández-de-Retana et al. Scientific Reports
- Seed-competent high-molecular-weight tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients
- (2016) Shuko Takeda et al. ANNALS OF NEUROLOGY
- TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia
- (2016) Felix L. Yeh et al. NEURON
- ESCRTs are everywhere
- (2015) J. H. Hurley EMBO JOURNAL
- Tau and neurodegenerative disease: the story so far
- (2015) Khalid Iqbal et al. Nature Reviews Neurology
- On the lag phase in amyloid fibril formation
- (2015) Paolo Arosio et al. PHYSICAL CHEMISTRY CHEMICAL PHYSICS
- Deficiency of Clusterin Exacerbates High-Fat Diet-Induced Insulin Resistance in Male Mice
- (2014) Min Jung Kwon et al. ENDOCRINOLOGY
- Stages and Conformations of the Tau Repeat Domain during Aggregation and Its Effect on Neuronal Toxicity
- (2014) Satish Kumar et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Active Cage Mechanism of Chaperonin-Assisted Protein Folding Demonstrated at Single-Molecule Level
- (2014) Amit J. Gupta et al. JOURNAL OF MOLECULAR BIOLOGY
- Addition of exogenous α-synuclein preformed fibrils to primary neuronal cultures to seed recruitment of endogenous α-synuclein to Lewy body and Lewy neurite–like aggregates
- (2014) Laura A Volpicelli-Daley et al. Nature Protocols
- Proteopathic tau seeding predicts tauopathy in vivo
- (2014) B. B. Holmes et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Extracellular Chaperones and Proteostasis
- (2013) Amy R. Wyatt et al. Annual Review of Biochemistry
- Parkinson's disease dementia: convergence of α-synuclein, tau and amyloid-β pathologies
- (2013) David J. Irwin et al. NATURE REVIEWS NEUROSCIENCE
- Simple piggyBac transposon-based mammalian cell expression system for inducible protein production
- (2013) Z. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds
- (2013) B. B. Holmes et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature
- (2012) Peter T. Nelson et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- The Role of Clusterin in Alzheimer’s Disease: Pathways, Pathogenesis, and Therapy
- (2012) Jin-Tai Yu et al. MOLECULAR NEUROBIOLOGY
- Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt–PCP–JNK pathway
- (2012) R Killick et al. MOLECULAR PSYCHIATRY
- Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion
- (2012) Teresa L. M. Thurston et al. NATURE
- Structure-guided evolution of cyan fluorescent proteins towards a quantum yield of 93%
- (2012) Joachim Goedhart et al. Nature Communications
- Plasma Clusterin and the Risk of Alzheimer Disease
- (2011) Elisabeth M. C. Schrijvers JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Stages of the Pathologic Process in Alzheimer Disease: Age Categories From 1 to 100 Years
- (2011) Heiko Braak et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- The extracellular chaperone clusterin sequesters oligomeric forms of the amyloid-β1−40 peptide
- (2011) Priyanka Narayan et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Association of Plasma Clusterin Concentration With Severity, Pathology, and Progression in Alzheimer Disease
- (2010) Madhav Thambisetty et al. ARCHIVES OF GENERAL PSYCHIATRY
- CSF markers of neurodegeneration in Parkinson’s disease
- (2010) Hana Přikrylová Vranová et al. JOURNAL OF NEURAL TRANSMISSION
- Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration
- (2010) Brian R. Hoover et al. NEURON
- A Flow Cytometry-Based FRET Assay to Identify and Analyse Protein-Protein Interactions in Living Cells
- (2010) Carina Banning et al. PLoS One
- Clusterin regulates transthyretin amyloidosis
- (2009) Ko-Woon Lee et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- E46K Parkinson’s-Linked Mutation Enhances C-Terminal-to-N-Terminal Contacts in α-Synuclein
- (2009) Carla C. Rospigliosi et al. JOURNAL OF MOLECULAR BIOLOGY
- Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
- (2009) Jean-Charles Lambert et al. NATURE GENETICS
- Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
- (2009) Denise Harold et al. NATURE GENETICS
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now