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Title
Challenges and solutions for therapeutic TCR‐based agents
Authors
Keywords
-
Journal
IMMUNOLOGICAL REVIEWS
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2023-07-17
DOI
10.1111/imr.13233
References
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Note: Only part of the references are listed.- Facile repurposing of peptide–MHC-restricted antibodies for cancer immunotherapy
- (2023) Xinbo Yang et al. NATURE BIOTECHNOLOGY
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- (2022) Miranda C. Lahman et al. Science Translational Medicine
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- (2022) Martin G. Klatt et al. BLOOD
- Challenges of the Immunotherapy: Perspectives and Limitations of the Immune Checkpoint Inhibitor Treatment
- (2022) Paula Dobosz et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- First soluble TCR therapy opens ‘new universe’ of cancer targets
- (2022) Elie Dolgin NATURE BIOTECHNOLOGY
- Engineered cellular immunotherapies in cancer and beyond
- (2022) Amanda V. Finck et al. NATURE MEDICINE
- Immunogenicity and therapeutic targeting of a public neoantigen derived from mutated PIK3CA
- (2022) Smita S. Chandran et al. NATURE MEDICINE
- A TCR mimic monoclonal antibody for the HPV-16 E7-epitope p11-19/HLA-A*02:01 complex
- (2022) Tao Dao et al. PLoS One
- TCR-mimic bispecific antibodies to target the HIV-1 reservoir
- (2022) Srona Sengupta et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Molecular signatures of antitumor neoantigen-reactive T cells from metastatic human cancers
- (2022) Frank J. Lowery et al. SCIENCE
- Emerging Strategies in TCR-Engineered T Cells
- (2022) Fang Wei et al. Frontiers in Immunology
- Mechanisms of MHC-I Downregulation and Role in Immunotherapy Response
- (2022) Brandie C. Taylor et al. Frontiers in Immunology
- Engineering γδ T Cells: Recognizing and Activating on Their Own Way
- (2022) Ruoyu Dong et al. Frontiers in Immunology
- To go or not to go? Biological logic gating engineered T cells
- (2022) Rebecca C Abbott et al. Journal for ImmunoTherapy of Cancer
- A TCR mimic monoclonal antibody reactive with the “public” phospho-neoantigen pIRS2/HLA-A*02:01 complex
- (2022) Tao Dao et al. JCI Insight
- Adoptive Immunotherapy With Engineered iNKT Cells to Target Cancer Cells and the Suppressive Microenvironment
- (2022) Gloria Delfanti et al. Frontiers in Medicine
- Dark genome, bright ideas: Recent approaches to harness transposable elements in immunotherapies
- (2022) Ashley Reid Cahn et al. CANCER CELL
- A novel antibody-TCR (AbTCR) T-cell therapy is safe and effective against CD19-positive relapsed/refractory B-cell lymphoma
- (2022) Pengcheng He et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer
- (2022) Andrea Cercek et al. NEW ENGLAND JOURNAL OF MEDICINE
- Gamma Delta T-Cell Based Cancer Immunotherapy: Past-Present-Future
- (2022) José Saura-Esteller et al. Frontiers in Immunology
- Application and Design of Switches Used in CAR
- (2022) Paweł Głowacki et al. Cells
- TCR-engineered iNKT cells induce robust antitumor response by dual targeting cancer and suppressive myeloid cells
- (2022) Gloria Delfanti et al. Science Immunology
- Combination strategies to durably suppress HIV-1: Soluble T cell receptors
- (2022) Zoë Wallace et al. Journal of Virus Eradication
- Natural killer T cells and other innate-like T lymphocytes as emerging platforms for allogeneic cancer cell therapy
- (2022) Amy N. Courtney et al. BLOOD
- Joining Forces for Cancer Treatment: From “TCR versus CAR” to “TCR and CAR”
- (2022) Karin Teppert et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Non-viral precision T cell receptor replacement for personalized cell therapy
- (2022) Susan P. Foy et al. NATURE
- HLA class I loss in colorectal cancer: implications for immune escape and immunotherapy
- (2021) Per Anderson et al. Cellular & Molecular Immunology
- The SIRPα–CD47 immune checkpoint in NK cells
- (2021) Tobias Deuse et al. JOURNAL OF EXPERIMENTAL MEDICINE
- CRISPR/Cas9-mediated knockout of clinically relevant alloantigenes in human primary T cells
- (2021) Elahe Kamali et al. BMC BIOTECHNOLOGY
- TCR-engineered T cells targeting E7 for patients with metastatic HPV-associated epithelial cancers
- (2021) Nisha B. Nagarsheth et al. NATURE MEDICINE
- Targeting a neoantigen derived from a common TP53 mutation
- (2021) Emily Han-Chung Hsiue et al. SCIENCE
- Cancer Immune Evasion Through Loss of MHC Class I Antigen Presentation
- (2021) Karthik Dhatchinamoorthy et al. Frontiers in Immunology
- HLA Class I Knockout Converts Allogeneic Primary NK Cells Into Suitable Effectors for “Off-the-Shelf” Immunotherapy
- (2021) Keven Hoerster et al. Frontiers in Immunology
- Bispecific antibodies targeting mutant RAS neoantigens
- (2021) Jacqueline Douglass et al. Science Immunology
- CAR-T cell therapy: current limitations and potential strategies
- (2021) Robert C. Sterner et al. Blood Cancer Journal
- Neoantigen: A New Breakthrough in Tumor Immunotherapy
- (2021) Zheying Zhang et al. Frontiers in Immunology
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- (2021) Abraham Nissani et al. Journal for ImmunoTherapy of Cancer
- HLA Ligand Atlas: a benign reference of HLA-presented peptides to improve T-cell-based cancer immunotherapy
- (2021) Ana Marcu et al. Journal for ImmunoTherapy of Cancer
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- (2021) Christian Augsberger et al. BLOOD
- Perspectives of tumor-infiltrating lymphocyte treatment in solid tumors
- (2021) Shuhang Wang et al. BMC Medicine
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- (2021) Noam Levin et al. CLINICAL CANCER RESEARCH
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- (2021) Federico Simonetta et al. CLINICAL CANCER RESEARCH
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- (2021) Nengzhi Pang et al. Journal of Hematology & Oncology
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- (2021) Zhijian Duan et al. MOLECULAR CANCER THERAPEUTICS
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- (2021) Steven A. Rosenberg MOLECULAR MEDICINE
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- (2021) Leila Peraro et al. MOLECULAR THERAPY
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- (2021) Paul Nathan et al. NEW ENGLAND JOURNAL OF MEDICINE
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- (2020) Jan A. Rath et al. Science Advances
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- (2020) Thomas J. Gardner et al. Cancers
- Strategies for Genetically Engineering Hypoimmunogenic Universal Pluripotent Stem Cells
- (2020) Wei Zhao et al. iScience
- Key Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction
- (2020) Daniel K. Wells et al. CELL
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- (2020) Patrick A. Ott et al. CELL
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- (2020) Dieter Kabelitz et al. Cellular & Molecular Immunology
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- (2020) Gal Cafri et al. JOURNAL OF CLINICAL INVESTIGATION
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- (2020) Khue G. Nguyen et al. Frontiers in Immunology
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- (2020) Martin G. Klatt et al. JCI Insight
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- (2020) Yuji Tokunaga et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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- (2020) Yuanzhang Fang et al. JOURNAL OF CLINICAL INVESTIGATION
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- (2020) May Daher et al. Cancer Discovery
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- (2020) Sheng Yu et al. Immunotherapy
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- (2019) Kevin Michael Boehm et al. BMC BIOINFORMATICS
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- (2019) Amanda C. Herrmann et al. Frontiers in Immunology
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- (2019) Nadia Mensali et al. EBioMedicine
- T cell antigen discovery via signaling and antigen-presenting bifunctional receptors
- (2019) Alok V. Joglekar et al. NATURE METHODS
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- (2019) Parisa Malekzadeh et al. JOURNAL OF CLINICAL INVESTIGATION
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- (2019) Ayhan Parlar et al. EUROPEAN JOURNAL OF IMMUNOLOGY
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- (2019) Isabel Prager et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Nanobody-based CAR T cells that target the tumor microenvironment inhibit the growth of solid tumors in immunocompetent mice
- (2019) Yushu Joy Xie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Elevated neoantigen levels in tumors with somatic mutations in the HLA-A, HLA-B, HLA-C and B2M genes
- (2019) Andrea Castro et al. BMC Medical Genomics
- Novel TCR-based biologics: mobilising T cells to warm ‘cold’ tumours
- (2019) Kate L. Lowe et al. CANCER TREATMENT REVIEWS
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- (2019) Isabel Prager et al. JOURNAL OF EXPERIMENTAL MEDICINE
- CAR-T cells secreting BiTEs circumvent antigen escape without detectable toxicity
- (2019) Bryan D. Choi et al. NATURE BIOTECHNOLOGY
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- (2019) Aude G. Chapuis et al. NATURE MEDICINE
- Unique Neoantigens Arise from Somatic Mutations in Patients with Gastrointestinal Cancers
- (2019) Maria R. Parkhurst et al. Cancer Discovery
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- (2019) Carino Gurjao et al. Cancer Immunology Research
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- (2019) Wolf-Henning Boehncke et al. Frontiers in Immunology
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- (2019) Francesca Garofano et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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- (2019) Qinghua He et al. Journal of Hematology & Oncology
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- (2019) Emma C Morris et al. BLOOD
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- Framework engineering to produce dominant T cell receptors with enhanced antigen-specific function
- (2019) Sharyn Thomas et al. Nature Communications
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- (2019) Siranush Sarkizova et al. NATURE BIOTECHNOLOGY
- Engineering strategies to overcome the current roadblocks in CAR T cell therapy
- (2019) Sarwish Rafiq et al. Nature Reviews Clinical Oncology
- New Insights into Graft-Versus-Host Disease and Graft Rejection
- (2018) Eric Perkey et al. Annual Review of Pathology-Mechanisms of Disease
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- (2018) Luigi Mari et al. GASTROENTEROLOGY
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- (2018) Wei Zhu et al. HEPATOLOGY
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- (2018) Keishi Adachi et al. NATURE BIOTECHNOLOGY
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- (2018) Li Tang et al. NATURE BIOTECHNOLOGY
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- (2018) Nikolaos Zacharakis et al. NATURE MEDICINE
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- (2018) Na Luo et al. Nature Communications
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- (2018) Natnaree Siriwon et al. Cancer Immunology Research
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- (2018) Jonathan Fisher et al. Frontiers in Immunology
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- (2018) Benjamin J. Wolf et al. Frontiers in Immunology
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- (2018) Gray Kueberuwa et al. Molecular Therapy-Oncolytics
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- (2018) Yasushi Akahori et al. BLOOD
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- (2018) Sarwish Rafiq et al. NATURE BIOTECHNOLOGY
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- (2018) Timothy P. Riley et al. Nature Chemical Biology
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- (2018) K. G. Paulson et al. Nature Communications
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- (2018) Yibo Yin et al. Molecular Therapy-Oncolytics
- The Immune Epitope Database (IEDB): 2018 update
- (2018) Randi Vita et al. NUCLEIC ACIDS RESEARCH
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- (2018) Saidulu Mattapally et al. Journal of the American Heart Association
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- (2018) Yiyang Xu et al. Cell Discovery
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- (2017) Aaron Y. Chang et al. JOURNAL OF CLINICAL INVESTIGATION
- Identification of essential genes for cancer immunotherapy
- (2017) Shashank J. Patel et al. NATURE
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- (2017) Germán G Gornalusse et al. NATURE BIOTECHNOLOGY
- Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade
- (2017) Dung T. Le et al. SCIENCE
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- (2017) Moshe Sade-Feldman et al. Nature Communications
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- (2017) Zhilong Zhao et al. Oncotarget
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- (2017) Xinyue Dong et al. Theranostics
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- (2017) Markus Chmielewski et al. Cell Reports
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- (2017) Andrea Majoros et al. Frontiers in Immunology
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- (2016) Jianjun Gao et al. CELL
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- (2016) Stephanie Gras et al. IMMUNITY
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- (2016) Niloufar Ataie et al. JOURNAL OF MOLECULAR BIOLOGY
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- (2016) S Rafiq et al. LEUKEMIA
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- (2016) Challice L Bonifant et al. MOLECULAR THERAPY
- Prospects for gene-engineered T cell immunotherapy for solid cancers
- (2016) Christopher A Klebanoff et al. NATURE MEDICINE
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- (2016) Eric Tran et al. NEW ENGLAND JOURNAL OF MEDICINE
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- (2016) Jesse M. Zaretsky et al. NEW ENGLAND JOURNAL OF MEDICINE
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- (2016) N. McGranahan et al. SCIENCE
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- (2016) T Colangelo et al. Cell Death & Disease
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- (2016) Eloah Rabello Suarez et al. Oncotarget
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- (2016) Michael T Bethune et al. eLife
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- (2015) Kanako Shimizu et al. PLoS One
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- (2015) S. A. Rosenberg et al. SCIENCE
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- (2015) B. M. Carreno et al. SCIENCE
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- (2015) Shan Liao et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
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- (2015) Michael L. van de Weijer et al. SEMINARS IN IMMUNOLOGY
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- (2014) Mariolina Salio et al. Annual Review of Immunology
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- (2014) T. Chodon et al. CLINICAL CANCER RESEARCH
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- (2014) Ludovic Durrieu et al. CYTOTHERAPY
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- (2014) Y Inaguma et al. GENE THERAPY
- Affinity-Based Selection of Regulatory T Cells Occurs Independent of Agonist-Mediated Induction of Foxp3 Expression
- (2014) L. M. Relland et al. JOURNAL OF IMMUNOLOGY
- Beyond model antigens: high-dimensional methods for the analysis of antigen-specific T cells
- (2014) Evan W Newell et al. NATURE BIOTECHNOLOGY
- Human Adenovirus-Specific γ/δ and CD8+ T Cells Generated by T-Cell Receptor Transfection to Treat Adenovirus Infection after Allogeneic Stem Cell Transplantation
- (2014) Jan Dörrie et al. PLoS One
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- (2014) Ge Zhang et al. Scientific Reports
- A Role for Naturally Occurring Alleles of Endoplasmic Reticulum Aminopeptidases in Tumor Immunity and Cancer Pre-Disposition
- (2014) Efstratios Stratikos et al. Frontiers in Oncology
- Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma
- (2013) G. P. Linette et al. BLOOD
- Combinatorial Peptide Libraries: Mining for Cell-Binding Peptides
- (2013) Bethany Powell Gray et al. CHEMICAL REVIEWS
- Treatment of patients with advanced cancer with the natural killer cell line NK-92
- (2013) Torsten Tonn et al. CYTOTHERAPY
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- (2013) Eric Gschweng et al. IMMUNOLOGICAL REVIEWS
- Engineering improved T cell receptors using an alanine-scan guided T cell display selection system
- (2013) Karolina Malecek et al. JOURNAL OF IMMUNOLOGICAL METHODS
- Cancer Regression and Neurological Toxicity Following Anti-MAGE-A3 TCR Gene Therapy
- (2013) Richard A. Morgan et al. JOURNAL OF IMMUNOTHERAPY
- Treatment of Metastatic Renal Cell Carcinoma With CAIX CAR-engineered T cells: Clinical Evaluation and Management of On-target Toxicity
- (2013) Cor HJ Lamers et al. MOLECULAR THERAPY
- T-cell receptor affinity and avidity defines antitumor response and autoimmunity in T-cell immunotherapy
- (2013) S. Zhong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Engineered SIRP Variants as Immunotherapeutic Adjuvants to Anticancer Antibodies
- (2013) K. Weiskopf et al. SCIENCE
- Targeting the Intracellular WT1 Oncogene Product with a Therapeutic Human Antibody
- (2013) T. Dao et al. Science Translational Medicine
- Identification of a Titin-Derived HLA-A1-Presented Peptide as a Cross-Reactive Target for Engineered MAGE A3-Directed T Cells
- (2013) B. J. Cameron et al. Science Translational Medicine
- Tumor-targeted T cells modified to secrete IL-12 eradicate systemic tumors without need for prior conditioning
- (2012) H. J. Pegram et al. BLOOD
- A foundation for universal T-cell based immunotherapy: T cells engineered to express a CD19-specific chimeric-antigen-receptor and eliminate expression of endogenous TCR
- (2012) H. Torikai et al. BLOOD
- Monoclonal TCR-redirected tumor cell killing
- (2012) Nathaniel Liddy et al. NATURE MEDICINE
- IPD—the Immuno Polymorphism Database
- (2012) James Robinson et al. NUCLEIC ACIDS RESEARCH
- MHC Class I TCR Engineered Anti-Tumor CD4 T Cells: Implications For Cancer Immunotherapy
- (2012) Arvind Chhabra Endocrine Metabolic & Immune Disorders-Drug Targets
- The privileged immunity of immune privileged organs: the case of the eye
- (2012) Inbal Benhar et al. Frontiers in Immunology
- Redirecting T cells against cancer cells by transfer of a broadly tumor-reactive T-cell receptor
- (2011) V. Marcu-Malina et al. BLOOD
- An anti-PR1/HLA-A2 T-cell receptor-like antibody mediates complement-dependent cytotoxicity against acute myeloid leukemia progenitor cells
- (2011) A. Sergeeva et al. BLOOD
- Dual-functional capability of CD3+CD56+ CIK cells, a T-cell subset that acquires NK function and retains TCR-mediated specific cytotoxicity
- (2011) A. Pievani et al. BLOOD
- Molecular dynamics simulations and drug discovery
- (2011) Jacob D Durrant et al. BMC BIOLOGY
- Durable Complete Responses in Heavily Pretreated Patients with Metastatic Melanoma Using T-Cell Transfer Immunotherapy
- (2011) S. A. Rosenberg et al. CLINICAL CANCER RESEARCH
- Down-regulation of Human Leukocyte Antigen class I heavy chain in tumors is associated with a poor prognosis in advanced esophageal cancer patients
- (2011) KIMITAKA TANAKA et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Clinical Cancer Therapy by NK Cells via Antibody-Dependent Cell-Mediated Cytotoxicity
- (2011) Kory L. Alderson et al. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
- CD4+ T-Cell Help in the Tumor Milieu Is Required for Recruitment and Cytolytic Function of CD8+ T Lymphocytes
- (2010) R. Bos et al. CANCER RESEARCH
- Tumor-Specific CD8+ T Cells Expressing Interleukin-12 Eradicate Established Cancers in Lymphodepleted Hosts
- (2010) S. P. Kerkar et al. CANCER RESEARCH
- Anti-CD47 Antibody Synergizes with Rituximab to Promote Phagocytosis and Eradicate Non-Hodgkin Lymphoma
- (2010) Mark P. Chao et al. CELL
- Efficient lysis of rhabdomyosarcoma cells by cytokine-induced killer cells: implications for adoptive immunotherapy after allogeneic stem cell transplantation
- (2010) S. Kuci et al. HAEMATOLOGICA
- Structure and function of immunoglobulins
- (2010) Harry W. Schroeder et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- TCR Mimic Monoclonal Antibody Targets a Specific Peptide/HLA Class I Complex and Significantly Impedes Tumor Growth In Vivo Using Breast Cancer Models
- (2010) Bhavna Verma et al. JOURNAL OF IMMUNOLOGY
- Evidence for a TCR Affinity Threshold Delimiting Maximal CD8 T Cell Function
- (2010) D. A. Schmid et al. JOURNAL OF IMMUNOLOGY
- Engineering CD19-specific T lymphocytes with interleukin-15 and a suicide gene to enhance their anti-lymphoma/leukemia effects and safety
- (2010) V Hoyos et al. LEUKEMIA
- T Cells Targeting Carcinoembryonic Antigen Can Mediate Regression of Metastatic Colorectal Cancer but Induce Severe Transient Colitis
- (2010) Maria R Parkhurst et al. MOLECULAR THERAPY
- Induction of Lethal Graft-versus-Host Disease by Anti-CD137 Monoclonal Antibody in Mice Prone to Chronic Graft-versus-Host Disease
- (2009) Wonyoung Kim et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen
- (2009) L. A. Johnson et al. BLOOD
- The Multiple Mechanisms of T Cell Receptor Cross-reactivity
- (2009) Yiyuan Yin et al. IMMUNITY
- Rational development of high-affinity T-cell receptor-like antibodies
- (2009) G. Stewart-Jones et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hypermethylation of HLA class I gene is associated with HLA class I down-regulation in human gastric cancer
- (2009) Q. Ye et al. TISSUE ANTIGENS
- Infusion of the allogeneic cell line NK-92 in patients with advanced renal cell cancer or melanoma: a phase I trial
- (2008) S. Arai et al. CYTOTHERAPY
- Adoptive Cell Therapy for Patients with Melanoma, Using Tumor-Infiltrating Lymphocytes Genetically Engineered to Secrete Interleukin-2
- (2008) Bianca Heemskerk et al. HUMAN GENE THERAPY
- Arthritis induced by posttranslationally modified (citrullinated) fibrinogen in DR4-IE transgenic mice
- (2008) Jonathan A. Hill et al. JOURNAL OF EXPERIMENTAL MEDICINE
- BLOSUM62 miscalculations improve search performance
- (2008) Mark P Styczynski et al. NATURE BIOTECHNOLOGY
- Phosphorylation-dependent interaction between antigenic peptides and MHC class I: a molecular basis for the presentation of transformed self
- (2008) Fiyaz Mohammed et al. NATURE IMMUNOLOGY
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