Hypoxia and hypoxia-inducible factor (HIF) downregulate antigen-presenting MHC class I molecules limiting tumor cell recognition by T cells

Immunological mechanisms of the antitumor effects of supplemental oxygenation

(2015) Stephen M. Hatfield et al.   Science Translational Medicine

Mechanisms of Hypoxia-Mediated Immune Escape in Cancer

(2014) I. B. Barsoum et al.   CANCER RESEARCH

ROS Function in Redox Signaling and Oxidative Stress

(2014) Michael Schieber et al.   CURRENT BIOLOGY

Regulation of MHC Class I Expression by Foxp3 and Its Effect on Regulatory T Cell Function

(2014) J. Mu et al.   JOURNAL OF IMMUNOLOGY

Systemic oxygenation weakens the hypoxia and hypoxia inducible factor 1α-dependent and extracellular adenosine-mediated tumor protection

(2014) Stephen M. Hatfield et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Harnessing the antigenic fingerprint of each individual cancer for immunotherapy of human cancer: genomics shows a new way and its challenges

(2013) Pramod K. Srivastava et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

HIF expression and the role of hypoxic microenvironments within primary tumours as protective sites driving cancer stem cell renewal and metastatic progression

(2013) B. Philip et al.   CARCINOGENESIS

HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations

(2013) Gregg L. Semenza   JOURNAL OF CLINICAL INVESTIGATION

Major Histocompatibility Complex Class I Core Promoter Elements Are Not Essential for Transcriptionin vivo

(2013) Zohar S. Barbash et al.   MOLECULAR AND CELLULAR BIOLOGY

Innate and adaptive immune cells in the tumor microenvironment

(2013) Thomas F Gajewski et al.   NATURE IMMUNOLOGY

Microenvironmental regulation of tumor progression and metastasis

(2013) Daniela F Quail et al.   NATURE MEDICINE

Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting

(2012) Hirokazu Matsushita et al.   NATURE

Purinergic Signaling during Inflammation

(2012) Holger K. Eltzschig et al.   NEW ENGLAND JOURNAL OF MEDICINE

The VHL/HIF axis in clear cell renal carcinoma

(2012) Chuan Shen et al.   SEMINARS IN CANCER BIOLOGY

Immunotherapy eradicates metastases with reversible defects in MHC class I expression

(2011) Cristina Garrido et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Peptide transporter TAP mediates between competing antigen sources generating distinct surface MHC class I peptide repertoires

(2011) Cláudia C. Oliveira et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mutations of the von Hippel–Lindau gene confer increased susceptibility to natural killer cells of clear-cell renal cell carcinoma

(2011) A Perier et al.   ONCOGENE

In vivo T Cell Activation in Lymphoid Tissues is Inhibited in the Oxygen-Poor Microenvironment

(2011) Akio Ohta et al.   Frontiers in Immunology

Expression Regulation of Major Histocompatibility Complex Class I and Class II Encoding Genes

(2011) Peter J. van den Elsen   Frontiers in Immunology

Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts

(2009) David R. Mole et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regressing and progressing metastatic lesions: resistance to immunotherapy is predetermined by irreversible HLA class I antigen alterations

(2008) Natalia Aptsiauri et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Hypoxia Increases Tumor Cell Shedding of MHC Class I Chain-Related Molecule: Role of Nitric Oxide

(2008) D. R. Siemens et al.   CANCER RESEARCH

Analysis of HLA class I expression in progressing and regressing metastatic melanoma lesions after immunotherapy

(2008) Rafael Carretero et al.   IMMUNOGENETICS