Predicting Cross-Reactivity and Antigen Specificity of T Cell Receptors

Mutation position is an important determinant for predicting cancer neoantigens

(2020) Aude-Hélène Capietto et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer’s disease

(2020) David Gate et al.   NATURE

Biophysicochemical motifs in T cell receptor sequences distinguish repertoires from tumor-infiltrating lymphocytes and adjacent healthy tissue

(2019) Jared Ostmeyer et al.   CANCER RESEARCH

T cell antigen discovery via trogocytosis

(2019) Guideng Li et al.   NATURE METHODS

T cell antigen discovery via signaling and antigen-presenting bifunctional receptors

(2019) Alok V. Joglekar et al.   NATURE METHODS

Deciphering CD4+ T cell specificity using novel MHC–TCR chimeric receptors

(2019) Jan Kisielow et al.   NATURE IMMUNOLOGY

Using T Cell Receptor Repertoires to Understand the Principles of Adaptive Immune Recognition

(2019) Philip Bradley et al.   Annual Review of Immunology

Broad cross-reactivity of the T-cell repertoire achieves specific and sufficiently rapid target searching

(2019) Jin Xu et al.   JOURNAL OF THEORETICAL BIOLOGY

Cross‐reactivity in allergy: a double‐edged sword

(2019) Anna Pomés et al.   ALLERGY

TCR3d: The T cell receptor structural repertoire database

(2019) Ragul Gowthaman et al.   BIOINFORMATICS

Balancing sensitivity and specificity in distinguishing TCR groups by CDR sequence similarity

(2019) Neerja Thakkar et al.   BMC BIOINFORMATICS

Clonal replacement of tumor-specific T cells following PD-1 blockade

(2019) Kathryn E. Yost et al.   NATURE MEDICINE

A cell topography-based mechanism for ligand discrimination by the T cell receptor

(2019) Ricardo A. Fernandes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detecting T cell receptors involved in immune responses from single repertoire snapshots

(2019) Mikhail V. Pogorelyy et al.   PLOS BIOLOGY

Quantitative Prediction of the Landscape of T Cell Epitope Immunogenicity in Sequence Space

(2019) Masato Ogishi et al.   Frontiers in Immunology

Single T Cell Sequencing Demonstrates the Functional Role of αβ TCR Pairing in Cell Lineage and Antigen Specificity

(2019) Jason A. Carter et al.   Frontiers in Immunology

T-Scan: A Genome-wide Method for the Systematic Discovery of T Cell Epitopes

(2019) Tomasz Kula et al.   CELL

Machine-Learning Prediction of Tumor Antigen Immunogenicity in the Selection of Therapeutic Epitopes

(2019) Christof C. Smith et al.   Cancer Immunology Research

A Framework for Annotation of Antigen Specificities in High-Throughput T-Cell Repertoire Sequencing Studies

(2019) Mikhail V. Pogorelyy et al.   Frontiers in Immunology

T-Cell Receptor Cognate Target Prediction Based on Paired α and β Chain Sequence and Structural CDR Loop Similarities

(2019) Esteban Lanzarotti et al.   Frontiers in Immunology

Structure Based Prediction of Neoantigen Immunogenicity

(2019) Timothy P. Riley et al.   Frontiers in Immunology

Understanding TCR affinity, antigen specificity, and cross-reactivity to improve TCR gene-modified T cells for cancer immunotherapy

(2019) Timothy T. Spear et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

VDJdb in 2019: database extension, new analysis infrastructure and a T-cell receptor motif compendium

(2019) Dmitry V Bagaev et al.   NUCLEIC ACIDS RESEARCH

Identification of drug-specific public TCR driving severe cutaneous adverse reactions

(2019) Ren-You Pan et al.   Nature Communications

In vivo clonal expansion and phenotypes of hypocretin-specific CD4+ T cells in narcolepsy patients and controls

(2019) Wei Jiang et al.   Nature Communications

CDR3α drives selection of the immunodominant Epstein Barr virus (EBV) BRLF1-specific CD8 T cell receptor repertoire in primary infection

(2019) Larisa Kamga et al.   PLoS Pathogens

TCR Fingerprinting and Off-Target Peptide Identification

(2019) Armen R. Karapetyan et al.   Frontiers in Immunology

Investigation of Antigen-Specific T-Cell Receptor Clusters in Human Cancers

(2019) Hongyi Zhang et al.   CLINICAL CANCER RESEARCH

pyHVis3D: visualising molecular simulation deduced H-bond networks in 3D: application to T-cell receptor interactions

(2018) Bernhard Knapp et al.   BIOINFORMATICS

Antigen Identification for Orphan T Cell Receptors Expressed on Tumor-Infiltrating Lymphocytes

(2018) Marvin H. Gee et al.   CELL

Preclinical Strategies to Identify Off-Target Toxicity of High-Affinity TCRs

(2018) Helena M. Bijen et al.   MOLECULAR THERAPY

Altered Peptide Ligands Impact the Diversity of Polyfunctional Phenotypes in T Cell Receptor Gene-Modified T Cells

(2018) Timothy T. Spear et al.   MOLECULAR THERAPY

Immune recognition of somatic mutations leading to complete durable regression in metastatic breast cancer

(2018) Nikolaos Zacharakis et al.   NATURE MEDICINE

Stress-testing the relationship between T cell receptor/peptide-MHC affinity and cross-reactivity using peptide velcro

(2018) Marvin H. Gee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Native and Posttranslationally Modified HLA-B*57:01-Restricted HIV Envelope Derived Epitopes Using Immunoproteomics

(2018) Sri H. Ramarathinam et al.   PROTEOMICS

Computational Strategies for Dissecting the High-Dimensional Complexity of Adaptive Immune Repertoires

(2018) Enkelejda Miho et al.   Frontiers in Immunology

Single Cell T Cell Receptor Sequencing: Techniques and Future Challenges

(2018) Marco De Simone et al.   Frontiers in Immunology

On the viability of unsupervised T-cell receptor sequence clustering for epitope preference

(2018) Pieter Meysman et al.   BIOINFORMATICS

Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding

(2018) Leah V. Sibener et al.   CELL

T cell receptor cross-reactivity expanded by dramatic peptide–MHC adaptability

(2018) Timothy P. Riley et al.   Nature Chemical Biology

Exploring the pre-immune landscape of antigen-specific T cells

(2018) Mikhail V. Pogorelyy et al.   Genome Medicine

Improving T Cell Receptor On-Target Specificity via Structure-Guided Design

(2018) Lance M. Hellman et al.   MOLECULAR THERAPY

High-throughput determination of the antigen specificities of T cell receptors in single cells

(2018) Shu-Qi Zhang et al.   NATURE BIOTECHNOLOGY

The intersection of affinity and specificity in the development and optimization of T cell receptor based therapeutics

(2018) Timothy P. Riley et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Cross-Reactivity of Virus-Specific CD8+ T Cells Against Allogeneic HLA-C: Possible Implications for Pregnancy Outcome

(2018) Anita van der Zwan et al.   Frontiers in Immunology

Network Representation of T-Cell Repertoire— A Novel Tool to Analyze Immune Response to Cancer Formation

(2018) Avner Priel et al.   Frontiers in Immunology

Affinity-enhanced T-cell receptors for adoptive T-cell therapy targeting MAGE-A10: strategy for selection of an optimal candidate

(2018) Ellen C. Border et al.   OncoImmunology

A study of CDR3 loop dynamics reveals distinct mechanisms of peptide recognition by T-cell receptors exhibiting different levels of cross-reactivity

(2017) Yuko Tsuchiya et al.   IMMUNOLOGY

Comparative analysis of murine T-cell receptor repertoires

(2017) Mark Izraelson et al.   IMMUNOLOGY

Quantifiable predictive features define epitope-specific T cell receptor repertoires

(2017) Pradyot Dash et al.   NATURE

Identifying specificity groups in the T cell receptor repertoire

(2017) Jacob Glanville et al.   NATURE

A neoantigen fitness model predicts tumour response to checkpoint blockade immunotherapy

(2017) Marta Łuksza et al.   NATURE

An immunogenic personal neoantigen vaccine for patients with melanoma

(2017) Patrick A. Ott et al.   NATURE

Multiplexed quantification of proteins and transcripts in single cells

(2017) Vanessa M Peterson et al.   NATURE BIOTECHNOLOGY

Immunosequencing identifies signatures of cytomegalovirus exposure history and HLA-mediated effects on the T cell repertoire

(2017) Ryan O Emerson et al.   NATURE GENETICS

Simultaneous epitope and transcriptome measurement in single cells

(2017) Marlon Stoeckius et al.   NATURE METHODS

Broad TCR repertoire and diverse structural solutions for recognition of an immunodominant CD8+ T cell epitope

(2017) InYoung Song et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

STCRDab: the structural T-cell receptor database

(2017) Jinwoo Leem et al.   NUCLEIC ACIDS RESEARCH

Advanced Methodologies in High-Throughput Sequencing of Immune Repertoires

(2017) Simon Friedensohn et al.   TRENDS IN BIOTECHNOLOGY

Broad TCR repertoire and diverse structural solutions for recognition of an immunodominant CD8+ T cell epitope

(2017) InYoung Song et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Interpreting T-Cell Cross-reactivity through Structure: Implications for TCR-Based Cancer Immunotherapy

(2017) Dinler A. Antunes et al.   Frontiers in Immunology

An Analysis of Natural T Cell Responses to Predicted Tumor Neoepitopes

(2017) Anne-Mette Bjerregaard et al.   Frontiers in Immunology

Strategies to genetically engineer T cells for cancer immunotherapy

(2016) Timothy T. Spear et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Deep Mutational Scans as a Guide to Engineering High Affinity T Cell Receptor Interactions with Peptide-bound Major Histocompatibility Complex

(2016) Daniel T. Harris et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity

(2016) David K. Cole et al.   JOURNAL OF CLINICAL INVESTIGATION

All-Atom Molecular Dynamics of Virus Capsids as Drug Targets

(2016) Juan R. Perilla et al.   Journal of Physical Chemistry Letters

Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA barcodes

(2016) Amalie Kai Bentzen et al.   NATURE BIOTECHNOLOGY

Hydrophobic CDR3 residues promote the development of self-reactive T cells

(2016) Brian D Stadinski et al.   NATURE IMMUNOLOGY

T cell fate and clonality inference from single-cell transcriptomes

(2016) Michael J T Stubbington et al.   NATURE METHODS

A generalized framework for computational design and mutational scanning of T-cell receptor binding interfaces

(2016) Timothy P. Riley et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Low-affinity CD4+ T cells are major responders in the primary immune response

(2016) Ryan J. Martinez et al.   Nature Communications

The contribution of major histocompatibility complex contacts to the affinity and kinetics of T cell receptor binding

(2016) Hao Zhang et al.   Scientific Reports

Hepatitis C virus infection from the perspective of heterologous immunity

(2016) Markus Cornberg et al.   Current Opinion in Virology

Cross-Reactivity of TCR Repertoire: Current Concepts, Challenges, and Implication for Allotransplantation

(2016) Nicolas Degauque et al.   Frontiers in Immunology

Direct molecular mimicry enables off-target cardiovascular toxicity by an enhanced affinity TCR designed for cancer immunotherapy

(2016) Marine C C Raman et al.   Scientific Reports

Expitope: a web server for epitope expression

(2015) K. Haase et al.   BIOINFORMATICS

Rapid, Precise, and Reproducible Prediction of Peptide–MHC Binding Affinities from Molecular Dynamics That Correlate Well with Experiment

(2015) Shunzhou Wan et al.   Journal of Chemical Theory and Computation

HCV epitope, homologous to multiple human protein sequences, induces a regulatory T cell response in infected patients

(2015) Phyllis T. Losikoff et al.   JOURNAL OF HEPATOLOGY

Improved structural method for T-cell cross-reactivity prediction

(2015) Marcus F.A. Mendes et al.   MOLECULAR IMMUNOLOGY

Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity

(2015) Jarrett J Adams et al.   NATURE IMMUNOLOGY

TCR contact residue hydrophobicity is a hallmark of immunogenic CD8+T cell epitopes

(2015) Diego Chowell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vaccination and heterologous immunity: educating the immune system

(2015) Anna Gil et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

Evaluation of non-reciprocal heterologous immunity between unrelated viruses

(2015) Jenny W. Che et al.   VIROLOGY

VDJtools: Unifying Post-analysis of T Cell Receptor Repertoires

(2015) Mikhail Shugay et al.   PLoS Computational Biology

Lower Affinity T Cells are Critical Components and Active Participants of the Immune Response

(2015) Ryan J. Martinez et al.   Frontiers in Immunology

Heterologous immunity between viruses

(2015) Raymond M. Welsh et al.   IMMUNOLOGICAL REVIEWS

Multiplex Identification of Antigen-Specific T Cell Receptors Using a Combination of Immune Assays and Immune Receptor Sequencing

(2015) Mark Klinger et al.   PLoS One

Tracking global changes induced in the CD4 T-cell receptor repertoire by immunization with a complex antigen using short stretches of CDR3 protein sequence

(2014) Niclas Thomas et al.   BIOINFORMATICS

Deconstructing the Peptide-MHC Specificity of T Cell Recognition

(2014) Michael E. Birnbaum et al.   CELL

Accumulation of Dynamic Catch Bonds between TCR and Agonist Peptide-MHC Triggers T Cell Signaling

(2014) Baoyu Liu et al.   CELL

NetTepi: an integrated method for the prediction of T cell epitopes

(2014) Thomas Trolle et al.   IMMUNOGENETICS

Accumulation of Serial Forces on TCR and CD8 Frequently Applied by Agonist Antigenic Peptides Embedded in MHC Molecules Triggers Calcium in T Cells

(2014) S. Pryshchep et al.   JOURNAL OF IMMUNOLOGY

Specific Increase in Potency via Structure-Based Design of a TCR

(2014) Karolina Malecek et al.   JOURNAL OF IMMUNOLOGY

Genetic Basis for Clinical Response to CTLA-4 Blockade in Melanoma

(2014) Alexandra Snyder et al.   NEW ENGLAND JOURNAL OF MEDICINE

Distinctive properties of identical twins' TCR repertoires revealed by high-throughput sequencing

(2014) I. V. Zvyagin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An induced rebinding model of antigen discrimination

(2014) Omer Dushek et al.   TRENDS IN IMMUNOLOGY

Computational Design of the Affinity and Specificity of a Therapeutic T Cell Receptor

(2014) Brian G. Pierce et al.   PLoS Computational Biology

Cross-Reactivity of T Cells and Its Role in the Immune System

(2013) Galina Petrova et al.   CRITICAL REVIEWS IN IMMUNOLOGY

Virus-Specific CD4+ Memory-Phenotype T Cells Are Abundant in Unexposed Adults

(2013) Laura F. Su et al.   IMMUNITY

NetMHCstab- predicting stability of peptide-MHC-I complexes; impacts for cytotoxic T lymphocyte epitope discovery

(2013) Kasper W. Jørgensen et al.   IMMUNOLOGY

T-cell Receptor (TCR)-Peptide Specificity Overrides Affinity-enhancing TCR-Major Histocompatibility Complex Interactions

(2013) David K. Cole et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Combinatorial HLA-peptide bead libraries for high throughput identification of CD8+ T cell specificity

(2013) Xiaoyan Pan et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Disparate Epitopes Mediating Protective Heterologous Immunity to Unrelated Viruses Share Peptide-MHC Structural Features Recognized by Cross-Reactive T Cells

(2013) Z. T. Shen et al.   JOURNAL OF IMMUNOLOGY

HLA Micropolymorphisms Strongly Affect Peptide-MHC Multimer-Based Monitoring of Antigen-Specific CD8+ T Cell Responses

(2013) M. M. van Buuren et al.   JOURNAL OF IMMUNOLOGY

Anti-IFN-  and Peptide-Tolerization Therapies Inhibit Acute Lung Injury Induced by Cross-Reactive Influenza A-Specific Memory T Cells

(2013) M. F. Wlodarczyk et al.   JOURNAL OF IMMUNOLOGY

Cancer Regression and Neurological Toxicity Following Anti-MAGE-A3 TCR Gene Therapy

(2013) Richard A. Morgan et al.   JOURNAL OF IMMUNOTHERAPY

Accurate structure prediction of peptide–MHC complexes for identifying highly immunogenic antigens

(2013) Min-Sun Park et al.   MOLECULAR IMMUNOLOGY

Reassessing target antigens for adoptive T-cell therapy

(2013) Christian S Hinrichs et al.   NATURE BIOTECHNOLOGY

Identification of a Titin-Derived HLA-A1-Presented Peptide as a Cross-Reactive Target for Engineered MAGE A3-Directed T Cells

(2013) B. J. Cameron et al.   Science Translational Medicine

Properties of MHC Class I Presented Peptides That Enhance Immunogenicity

(2013) Jorg J. A. Calis et al.   PLoS Computational Biology

Cellular-Level Versus Receptor-Level Response Threshold Hierarchies in T-Cell Activation

(2013) Hugo A. van den Berg et al.   Frontiers in Immunology

Structure-Based, Rational Design of T Cell Receptors

(2013) V. Zoete et al.   Frontiers in Immunology

Clonal Exhaustion as a Mechanism to Protect Against Severe Immunopathology and Death from an Overwhelming CD8 T Cell Response

(2013) Markus Cornberg et al.   Frontiers in Immunology

Peptide length determines the outcome of TCR/peptide-MHCI engagement

(2012) J. Ekeruche-Makinde et al.   BLOOD

Structural basis for self-recognition by autoimmune T-cell receptors

(2012) Yiyuan Yin et al.   IMMUNOLOGICAL REVIEWS

T-cell Receptor-optimized Peptide Skewing of the T-cell Repertoire Can Enhance Antigen Targeting

(2012) Julia Ekeruche-Makinde et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

T Cell Responses to Known Allergen Proteins Are Differently Polarized and Account for a Variable Fraction of Total Response to Allergen Extracts

(2012) C. Oseroff et al.   JOURNAL OF IMMUNOLOGY

A flexible docking approach for prediction of T cell receptor-peptide-MHC complexes

(2012) Brian G. Pierce et al.   PROTEIN SCIENCE

Loss of Anti-Viral Immunity by Infection with a Virus Encoding a Cross-Reactive Pathogenic Epitope

(2012) Alex T. Chen et al.   PLoS Pathogens

POPISK: T-cell reactivity prediction using support vector machines and string kernels

(2011) Chun-Wei Tung et al.   BMC BIOINFORMATICS

T Cell Receptor Signaling Is Limited by Docking Geometry to Peptide-Major Histocompatibility Complex

(2011) Jarrett J. Adams et al.   IMMUNITY

NetMHCcons: a consensus method for the major histocompatibility complex class I predictions

(2011) Edita Karosiene et al.   IMMUNOGENETICS

A Single Autoimmune T Cell Receptor Recognizes More Than a Million Different Peptides

(2011) Linda Wooldridge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Polyclonal CD8 T Cell Response to Influenza M158-66 Generates a Fully Connected Network of Cross-Reactive Clonotypes to Structurally Related Peptides: A Paradigm for Memory Repertoire Coverage of Novel Epitopes or Escape Mutants

(2011) G. V. Petrova et al.   JOURNAL OF IMMUNOLOGY

Conformational Melding Permits a Conserved Binding Geometry in TCR Recognition of Foreign and Self Molecular Mimics

(2011) O. Y. Borbulevych et al.   JOURNAL OF IMMUNOLOGY

How T cell receptors interact with peptide-MHCs: A multiple steered molecular dynamics study

(2011) Michel A. Cuendet et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Pathological Features of Heterologous Immunity Are Regulated by the Private Specificities of the Immune Repertoire

(2010) Siwei Nie et al.   AMERICAN JOURNAL OF PATHOLOGY

Search and clustering orders of magnitude faster than BLAST

(2010) Robert C. Edgar   BIOINFORMATICS

Allo-HLA reactivity of virus-specific memory T cells is common

(2010) A. L. Amir et al.   BLOOD

Dependence of T Cell Antigen Recognition on T Cell Receptor-Peptide MHC Confinement Time

(2010) Milos Aleksic et al.   IMMUNITY

CD8 Controls T Cell Cross-Reactivity

(2010) L. Wooldridge et al.   JOURNAL OF IMMUNOLOGY

CD8 T Cell Cross-Reactivity Networks Mediate Heterologous Immunity in Human EBV and Murine Vaccinia Virus Infections

(2010) M. Cornberg et al.   JOURNAL OF IMMUNOLOGY

Broad Cross-Reactive TCR Repertoires Recognizing Dissimilar Epstein-Barr and Influenza A Virus Epitopes

(2010) S. C. Clute et al.   JOURNAL OF IMMUNOLOGY

Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen

(2009) L. A. Johnson et al.   BLOOD

Comprehensive assessment of T-cell receptor  -chain diversity in    T cells

(2009) H. S. Robins et al.   BLOOD

T Cell Receptor Cross-reactivity Directed by Antigen-Dependent Tuning of Peptide-MHC Molecular Flexibility

(2009) Oleg Y. Borbulevych et al.   IMMUNITY

Quantitating T Cell Cross-Reactivity for Unrelated Peptide Antigens

(2009) J. Ishizuka et al.   JOURNAL OF IMMUNOLOGY

Phosphorylated self-peptides alter human leukocyte antigen class I-restricted antigen presentation and generate tumor-specific epitopes

(2009) Jan Petersen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Low-affinity peptides and T-cell selection

(2009) Andreas Ziegler et al.   TRENDS IN IMMUNOLOGY

A Multivalent and Cross-Protective Vaccine Strategy against Arenaviruses Associated with Human Disease

(2009) Maya F. Kotturi et al.   PLoS Pathogens

Relationship between CD8-dependent antigen recognition, T cell functional avidity, and tumor cell recognition

(2008) Tamson V. Moore et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

T-cell receptor binding affinities and kinetics: impact on T-cell activity and specificity

(2008) Jennifer D. Stone et al.   IMMUNOLOGY

Arthritis induced by posttranslationally modified (citrullinated) fibrinogen in DR4-IE transgenic mice

(2008) Jonathan A. Hill et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Phosphorylation-dependent interaction between antigenic peptides and MHC class I: a molecular basis for the presentation of transformed self

(2008) Fiyaz Mohammed et al.   NATURE IMMUNOLOGY

Amino Acid Similarity Accounts for T Cell Cross-Reactivity and for “Holes” in the T Cell Repertoire

(2008) Sune Frankild et al.   PLoS One

Structure-based design of a T-cell receptor leads to nearly 100-fold improvement in binding affinity for pepMHC

(2008) Jaafar N. Haidar et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS