Human Adenovirus-Specific γ/δ and CD8+ T Cells Generated by T-Cell Receptor Transfection to Treat Adenovirus Infection after Allogeneic Stem Cell Transplantation

A GMP-compliant protocol to expand and transfect cancer patient T cells with mRNA encoding a tumor-specific chimeric antigen receptor

(2014) Christian Krug et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Concurrent interaction of DCs with CD4+and CD8+T cells improves secondary CTL expansion: It takes three to tango

(2014) Stefanie Hoyer et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

First-in-Man Clinical Results With Good Manufacturing Practice (GMP)-compliant Polypeptide-expanded Adenovirus-specific T Cells After Haploidentical Hematopoietic Stem Cell Transplantation

(2014) René Geyeregger et al.   JOURNAL OF IMMUNOTHERAPY

Multicenter study of banked third-party virus-specific T cells to treat severe viral infections after hematopoietic stem cell transplantation

(2013) A. M. Leen et al.   BLOOD

Short-Term In-Vitro Expansion Improves Monitoring and Allows Affordable Generation of Virus-Specific T-Cells against Several Viruses for a Broad Clinical Application

(2013) René Geyeregger et al.   PLoS One

A Practical Approach to Immunotherapy of Hepatocellular Carcinoma Using T Cells Redirected Against Hepatitis B Virus

(2013) Sarene Koh et al.   Molecular Therapy-Nucleic Acids

Immune reconstitution and strategies for rebuilding the immune system after haploidentical stem cell transplantation

(2012) Lena Oevermann et al.   Annals of the New York Academy of Sciences

Extensive expansion of primary human gamma delta T cells generates cytotoxic effector memory cells that can be labeled with Feraheme for cellular MRI

(2012) Gabrielle M. Siegers et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Retracted:Antitumor activity of human γδ T cells transducted with CD8 and with T-cell receptors of tumor-specific cytotoxic T lymphocytes

(2012) Takeshi Hanagiri et al.   CANCER SCIENCE

Rapid Salvage Treatment With Virus-Specific T Cells for Therapy-Resistant Disease

(2012) M. Uhlin et al.   CLINICAL INFECTIOUS DISEASES

Strong and sustained effector function of memory- versus naïve-derived T cells upon T-cell receptor RNA transfer: Implications for cellular therapy

(2012) Simone Thomas et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Molecular Diagnosis and Management of Viral Infections in Hematopoietic Stem Cell Transplant Recipients

(2012) Sabine Breuer et al.   Molecular Diagnosis & Therapy

Redirecting T Cells to Ewing's Sarcoma Family of Tumors by a Chimeric NKG2D Receptor Expressed by Lentiviral Transduction or mRNA Transfection

(2012) Manfred Lehner et al.   PLoS One

European guidelines for diagnosis and treatment of adenovirus infection in leukemia and stem cell transplantation: summary of ECIL-4 (2011)

(2012) S. Matthes-Martin et al.   Transplant Infectious Disease

Third-party virus-specific T cells eradicate adenoviraemia but trigger bystander graft-versus-host disease

(2011) Waseem Qasim et al.   BRITISH JOURNAL OF HAEMATOLOGY

Involvement of CD56brightCD11c+ Cells in IL-18-Mediated Expansion of Human    T Cells

(2011) J. Tsuda et al.   JOURNAL OF IMMUNOLOGY

Treating cancer with genetically engineered T cells

(2011) Tristen S. Park et al.   TRENDS IN BIOTECHNOLOGY

Epidemiology of adenovirus type 5 neutralizing antibodies in healthy people and AIDS patients in Guangzhou, southern China

(2011) Caijun Sun et al.   VACCINE

Adoptive transfer of pp65-specific T cells for the treatment of chemorefractory cytomegalovirus disease or reactivation after haploidentical and matched unrelated stem cell transplantation

(2010) T. Feuchtinger et al.   BLOOD

Adoptive immunotherapy of cancer using ex vivo expanded human γδ T cells: A new approach

(2010) Pouneh Dokouhaki et al.   CANCER LETTERS

A phase I study of adoptive immunotherapy for recurrent non-small-cell lung cancer patients with autologous γδ T cells☆☆☆

(2010) Jun Nakajima et al.   EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY

Generation of HIV-1-specific T cells by electroporation of T-cell receptor RNA

(2009) Christian Hofmann et al.   AIDS

Cytotoxic T lymphocyte therapy with donor T cells prevents and treats adenovirus and Epstein-Barr virus infections after haploidentical and matched unrelated stem cell transplantation

(2009) A. M. Leen et al.   BLOOD

Functionally active virus-specific T cells that target CMV, adenovirus, and EBV can be expanded from naive T-cell populations in cord blood and will target a range of viral epitopes

(2009) P. J. Hanley et al.   BLOOD

Transfer of mRNA encoding recombinant immunoreceptors reprograms CD4+ and CD8+ T cells for use in the adoptive immunotherapy of cancer

(2009) K Birkholz et al.   GENE THERAPY

Large scale expansion of Vγ9Vδ2 T lymphocytes from human peripheral blood mononuclear cells after a positive selection using MACS “TCR γ/δ + T cell isolation kit”

(2009) Samuel Salot et al.   JOURNAL OF IMMUNOLOGICAL METHODS

A fast and robust method to clone and functionally validate T-cell receptors

(2009) Katrin Birkholz et al.   JOURNAL OF IMMUNOLOGICAL METHODS

CMV-Specific TCR-Transgenic T Cells for Immunotherapy

(2009) A. Schub et al.   JOURNAL OF IMMUNOLOGY

Generation of Human Dendritic Cells That Simultaneously Secrete IL-12 and Have Migratory Capacity by Adenoviral Gene Transfer of hCD40L in Combination With IFN-γ

(2009) Ilka Knippertz et al.   JOURNAL OF IMMUNOTHERAPY