Engineering γδ T Cells: Recognizing and Activating on Their Own Way
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Title
Engineering γδ T Cells: Recognizing and Activating on Their Own Way
Authors
Keywords
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Journal
Frontiers in Immunology
Volume 13, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2022-05-06
DOI
10.3389/fimmu.2022.889051
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Note: Only part of the references are listed.- CD6 is a target for cancer immunotherapy
- (2021) Jeffrey H. Ruth et al. JCI Insight
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- (2021) Baofu Zhang et al. MEDICAL ONCOLOGY
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- (2021) Cai Zhang et al. Cellular & Molecular Immunology
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- (2021) Robert Hudecek et al. Frontiers in Immunology
- CAR T cells: continuation in a revolution of immunotherapy
- (2020) Anurag K Singh et al. LANCET ONCOLOGY
- Genome-wide CRISPR–Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1
- (2020) Michael D. Crowther et al. NATURE IMMUNOLOGY
- Butyrophilin 2A1 is essential for phosphoantigen reactivity by γδ T cells
- (2020) Marc Rigau et al. SCIENCE
- A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1
- (2020) Jérôme Le Nours et al. SCIENCE
- In the Absence of a TCR Signal IL-2/IL-12/18-Stimulated γδ T Cells Demonstrate Potent Anti-Tumoral Function Through Direct Killing and Senescence Induction in Cancer Cells
- (2020) Karin Schilbach et al. Cancers
- Butyrophilin-2A1 Directly Binds Germline-Encoded Regions of the Vγ9Vδ2 TCR and Is Essential for Phosphoantigen Sensing
- (2020) Mohindar M. Karunakaran et al. IMMUNITY
- IL‐18R signaling is required for γδ T cell response and confers resistance to Trypanosoma cruzi infection
- (2020) Julia Barbalho da Mota et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Cancer immunotherapy with γδ T cells: many paths ahead of us
- (2020) Dieter Kabelitz et al. Cellular & Molecular Immunology
- Ligand recognition by the γδ TCR and discrimination between homeostasis and stress conditions
- (2020) Malte Deseke et al. Cellular & Molecular Immunology
- Gamma-Delta CAR-T Cells Show CAR-Directed and Independent Activity Against Leukemia
- (2020) Meir Rozenbaum et al. Frontiers in Immunology
- Diversity of Tumor-Infiltrating, γδ T-Cell Abundance in Solid Cancers
- (2020) Ghita Chabab et al. Cells
- Human γδ T cells recognize CD1b by two distinct mechanisms
- (2020) Josephine F. Reijneveld et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Expression of CD27 and CD28 on γδ T cells from the peripheral blood of patients with allergic rhinitis
- (2020) Qiong Wang et al. Experimental and Therapeutic Medicine
- Evaluating in vivo efficacy – toxicity profile of TEG001 in humanized mice xenografts against primary human AML disease and healthy hematopoietic cells
- (2019) Inez Johanna et al. Journal for ImmunoTherapy of Cancer
- Allogenic Vγ9Vδ2 T cell as new potential immunotherapy drug for solid tumor: a case study for cholangiocarcinoma
- (2019) Mohammed Alnaggar et al. Journal for ImmunoTherapy of Cancer
- Broad Cytotoxic Targeting of Acute Myeloid Leukemia by Polyclonal Delta One T Cells
- (2019) Biagio Di Lorenzo et al. Cancer Immunology Research
- Translating gammadelta (γδ) T cells and their receptors into cancer cell therapies
- (2019) Zsolt Sebestyen et al. NATURE REVIEWS DRUG DISCOVERY
- Vδ2 T-Cells Kill ZIKV-Infected Cells by NKG2D-Mediated Cytotoxicity
- (2019) Cimini et al. Microorganisms
- Adoptive CD8+ T cell therapy against cancer:Challenges and opportunities
- (2019) Xiaotao Jiang et al. CANCER LETTERS
- MUC1 as a target for CAR‐T therapy in head and neck squamous cell carinoma
- (2019) Zi Mei et al. Cancer Medicine
- Chimeric Antigen Receptor-Engineered Human Gamma Delta T Cells: Enhanced Cytotoxicity with Retention of Cross Presentation
- (2018) Anna Capsomidis et al. MOLECULAR THERAPY
- Enumeration, functional responses and cytotoxic capacity of MAIT cells in newly diagnosed and relapsed multiple myeloma
- (2018) Nicholas A. Gherardin et al. Scientific Reports
- Working in “NK Mode”: Natural Killer Group 2 Member D and Natural Cytotoxicity Receptors in Stress-Surveillance by γδ T Cells
- (2018) Bruno Silva-Santos et al. Frontiers in Immunology
- The NKG2D/NKG2DL Axis in the Crosstalk Between Lymphoid and Myeloid Cells in Health and Disease
- (2018) Ana Stojanovic et al. Frontiers in Immunology
- Addition of the C-terminus of CD6 to a chimeric antigen receptor enhances cytotoxicity and does not compromise expression
- (2018) Johannes Breuning et al. IMMUNOLOGY
- A novel antibody-TCR (AbTCR) platform combines Fab-based antigen recognition with gamma/delta-TCR signaling to facilitate T-cell cytotoxicity with low cytokine release
- (2018) Yiyang Xu et al. Cell Discovery
- Avoidance of On-Target Off-Tumor Activation Using a Co-stimulation-Only Chimeric Antigen Receptor
- (2017) Jonathan Fisher et al. MOLECULAR THERAPY
- Sensing of cell stress by human γδ TCR-dependent recognition of annexin A2
- (2017) Romain Marlin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phosphoantigen-induced conformational change of butyrophilin 3A1 (BTN3A1) and its implication on Vγ9Vδ2 T cell activation
- (2017) Siyi Gu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cytokine-mediated activation of human ex vivo-expanded Vγ9Vδ2 T cells
- (2017) Eisuke Domae et al. Oncotarget
- The role of CD27 in anti-viral T-cell immunity
- (2017) Emma J Grant et al. Current Opinion in Virology
- Assessment of tumor-infiltrating TCRVγ9Vδ2 γδ lymphocyte abundance by deconvolution of human cancers microarrays
- (2017) Marie Tosolini et al. OncoImmunology
- A Cholesterol-Based Allostery Model of T Cell Receptor Phosphorylation
- (2016) Mahima Swamy et al. IMMUNITY
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- (2016) Sobhan Roy et al. JOURNAL OF IMMUNOLOGY
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- (2016) Kangxia He et al. MOLECULAR MEDICINE
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- (2016) Feng Wang et al. NATURE IMMUNOLOGY
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- (2015) Yuejin Liang et al. EUROPEAN JOURNAL OF IMMUNOLOGY
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- (2015) Andrew J Gentles et al. NATURE MEDICINE
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- (2015) L. L. Lanier Cancer Immunology Research
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- (2014) Andrew Sandstrom et al. IMMUNITY
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- (2013) Drew C Deniger et al. MOLECULAR THERAPY
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- Increased Cholesterol Content in Gammadelta (γδ) T Lymphocytes Differentially Regulates Their Activation
- (2013) Hsin-Yuan Cheng et al. PLoS One
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- (2013) Renee M. Laird et al. PLoS One
- Key implication of CD277/butyrophilin-3 (BTN3A) in cellular stress sensing by a major human T-cell subset
- (2012) C. Harly et al. BLOOD
- The ganglioside antigen GD2 is surface-expressed in Ewing sarcoma and allows for MHC-independent immune targeting
- (2012) S Kailayangiri et al. BRITISH JOURNAL OF CANCER
- Mutant p53 Disrupts Mammary Tissue Architecture via the Mevalonate Pathway
- (2012) William A. Freed-Pastor et al. CELL
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- (2012) Xun Zeng et al. IMMUNITY
- B7-CD28 Costimulatory Signals Control the Survival and Proliferation of Murine and Human T Cells via IL-2 Production
- (2012) J. C. Ribot et al. JOURNAL OF IMMUNOLOGY
- Early IL-17 Production by Intrahepatic T Cells Is Important for Adaptive Immune Responses in Viral Hepatitis
- (2012) L. Hou et al. JOURNAL OF IMMUNOLOGY
- Cytomegalovirus and tumor stress surveillance by binding of a human γδ T cell antigen receptor to endothelial protein C receptor
- (2012) Carrie R Willcox et al. NATURE IMMUNOLOGY
- Interleukin 7 (IL-7) selectively promotes mouse and human IL-17-producing cells
- (2012) M.-L. Michel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Redirecting T cells against cancer cells by transfer of a broadly tumor-reactive T-cell receptor
- (2011) V. Marcu-Malina et al. BLOOD
- Differentiation of human peripheral blood V 1+ T cells expressing the natural cytotoxicity receptor NKp30 for recognition of lymphoid leukemia cells
- (2011) D. V. Correia et al. BLOOD
- CD27 costimulation augments the survival and antitumor activity of redirected human T cells in vivo
- (2011) D.-G. Song et al. BLOOD
- Phase I/II study of adoptive transfer of γδ T cells in combination with zoledronic acid and IL-2 to patients with advanced renal cell carcinoma
- (2011) Hirohito Kobayashi et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- CDR3δ -grafted γ9δ2T cells mediate effective antitumor reactivity
- (2011) Hui Zhao et al. Cellular & Molecular Immunology
- Modulation of γδ T cell responses by TLR ligands
- (2011) Daniela Wesch et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Role of NKG2D and its ligands in the anti-infectious activity of Vγ9Vδ2 T cells against intracellular bacteria
- (2011) Stéphanie Bessoles et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Ligation of the CD2 co-stimulatory receptor enhances IL-2 production from first-generation chimeric antigen receptor T cells
- (2011) E J Cheadle et al. GENE THERAPY
- Structure of the human activating natural cytotoxicity receptor NKp30 bound to its tumor cell ligand B7-H6
- (2011) Yili Li et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Caspase-1-Processed Cytokines IL-1 and IL-18 Promote IL-17 Production by and CD4 T Cells That Mediate Autoimmunity
- (2011) S. J. Lalor et al. JOURNAL OF IMMUNOLOGY
- CD70-CD27 interactions provide survival and proliferative signals that regulate T cell receptor-driven activation of human γδ peripheral blood lymphocytes
- (2010) Ana deBarros et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- NKG2D Costimulates Human V 9V 2 T Cell Antitumor Cytotoxicity through Protein Kinase C -Dependent Modulation of Early TCR-Induced Calcium and Transduction Signals
- (2010) S. Nedellec et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: Adaptive Versus Innate Receptor Signals Selectively Control the Pool Sizes of Murine IFN- - or IL-17-Producing T Cells upon Infection
- (2010) J. C. Ribot et al. JOURNAL OF IMMUNOLOGY
- Effect of IL-18 on Expansion of γδ T Cells Stimulated by Zoledronate and IL-2
- (2010) Wen Li et al. JOURNAL OF IMMUNOTHERAPY
- Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy
- (2010) Gavin M Bendle et al. NATURE MEDICINE
- The NKG2D ligand ULBP4 binds to TCR 9/ 2 and induces cytotoxicity to tumor cells through both TCR and NKG2D
- (2009) Y. Kong et al. BLOOD
- Interleukin-1 and IL-23 Induce Innate IL-17 Production from γδ T Cells, Amplifying Th17 Responses and Autoimmunity
- (2009) Caroline E. Sutton et al. IMMUNITY
- Reduced Expression of the Mevalonate Pathway Enzyme Farnesyl Pyrophosphate Synthase Unveils Recognition of Tumor Cells by V 9V 2 T Cells
- (2009) J. Li et al. JOURNAL OF IMMUNOLOGY
- IL-21-Mediated Potentiation of Antitumor Cytolytic and Proinflammatory Responses of Human V 9V 2 T Cells for Adoptive Immunotherapy
- (2009) A. Thedrez et al. JOURNAL OF IMMUNOLOGY
- CD27 is a thymic determinant of the balance between interferon-γ- and interleukin 17–producing γδ T cell subsets
- (2009) Julie C Ribot et al. NATURE IMMUNOLOGY
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