A network pharmacology- and transcriptomics-based investigation reveals an inhibitory role of β-sitosterol in glioma via the EGFR/MAPK signaling pathway

Entrectinib, a new multi-target inhibitor for cancer therapy

(2022) Qinghua Jiang et al.   BIOMEDICINE & PHARMACOTHERAPY

Resibufogenin Targets the ATP1A1 Signaling Cascade to Induce G2/M Phase Arrest and Inhibit Invasion in Glioma

(2022) Xun Zhang et al.   Frontiers in Pharmacology

Molecular Mechanism of β-Sitosterol and its Derivatives in Tumor Progression

(2022) Xingxun Bao et al.   Frontiers in Oncology

The molecular mechanisms and therapeutic strategies of EMT in tumor progression and metastasis

(2022) Yuhe Huang et al.   Journal of Hematology & Oncology

A bioinformatics and transcriptomics based investigation reveals an inhibitory role of Huanglian-Renshen-Decoction on hepatic glucose production of T2DM mice via PI3K/Akt/FoxO1 signaling pathway

(2021) Fan Wu et al.   PHYTOMEDICINE

An integrated network pharmacology and transcriptomic method to explore the mechanism of the total Rhizoma Coptidis alkaloids in improving diabetic nephropathy

(2021) Yaping Xiao et al.   JOURNAL OF ETHNOPHARMACOLOGY

A Network Pharmacological Approach to Reveal the Pharmacological Targets and Its Associated Biological Mechanisms of Prunetin-5-O-Glucoside against Gastric Cancer

(2021) Preethi Vetrivel et al.   Cancers

Circadian clock and cell cycle: Cancer and chronotherapy

(2021) Jing Yao et al.   ACTA HISTOCHEMICA

Potential Antimicrobial and Anticancer Activities of an Ethanol Extract from Bouea macrophylla

(2020) Ngoc Hong Nguyen et al.   MOLECULES

Quercetin Attenuates Atherosclerosis via Modulating Oxidized LDL-Induced Endothelial Cellular Senescence

(2020) Yue-Hua Jiang et al.   Frontiers in Pharmacology

Integrated analysis of the proteome and transcriptome in a MCAO mouse model revealed the molecular landscape during stroke progression

(2020) Litao Li et al.   Journal of Advanced Research

An Integrated Network, RNA Sequencing, and Experiment Pharmacology Approach Reveals the Active Component, Potential Target, and Mechanism of Gelsemium elegans in the Treatment of Colorectal Cancer

(2020) Lin Wang et al.   Frontiers in Oncology

Current status and contemporary approaches to the discovery of antitumor agents from higher plants

(2019) Garima Agarwal et al.   BIOTECHNOLOGY ADVANCES

β-Sitosterol and Gemcitabine Exhibit Synergistic Anti-pancreatic Cancer Activity by Modulating Apoptosis and Inhibiting Epithelial–Mesenchymal Transition by Deactivating Akt/GSK-3β Signaling

(2019) Zhang-qi Cao et al.   Frontiers in Pharmacology

Licochalcone A Inhibits Cellular Motility by Suppressing E-cadherin and MAPK Signaling in Breast Cancer

(2019) Wen-Chung Huang et al.   Cells

Context-dependent EMT programs in cancer metastasis

(2019) Nicole M. Aiello et al.   JOURNAL OF EXPERIMENTAL MEDICINE

RNF128 Promotes Invasion and Metastasis Via the EGFR/MAPK/MMP-2 Pathway in Esophageal Squamous Cell Carcinoma

(2019) Jing Gao et al.   Cancers

Understanding the Mechanistic Contribution of Herbal Extracts in Compound Kushen Injection With Transcriptome Analysis

(2019) Hanyuan Shen et al.   Frontiers in Oncology

Ubiquitin ligase RNF5 serves an important role in the development of human glioma

(2019) Yong Gao et al.   Oncology Letters

Cinobufagin Induces Cell Cycle Arrest at the G2/M Phase and Promotes Apoptosis in Malignant Melanoma Cells

(2019) Zhaohai Pan et al.   Frontiers in Oncology

Progress and Prospects of Recurrent Glioma: A Recent Scientometric Analysis of the Web of Science in 2019

(2019) Wenlin Chen et al.   World Neurosurgery

Lanatoside C Induces G2/M Cell Cycle Arrest and Suppresses Cancer Cell Growth by Attenuating MAPK, Wnt, JAK-STAT, and PI3K/AKT/mTOR Signaling Pathways

(2019) Dhanasekhar Reddy et al.   Biomolecules

Anti-tumour effects of beta-sitosterol are mediated by AMPK/PTEN/HSP90 axis in AGS human gastric adenocarcinoma cells and xenograft mouse models

(2018) Eun Ju Shin et al.   BIOCHEMICAL PHARMACOLOGY

Oxidative stress and dietary phytochemicals: Role in cancer chemoprevention and treatment

(2018) Shireen Chikara et al.   CANCER LETTERS

A glial blueprint for gliomagenesis

(2018) Dylan Laug et al.   NATURE REVIEWS NEUROSCIENCE

New Directions in the Treatment of Glioblastoma

(2018) Zachary Reitman et al.   SEMINARS IN NEUROLOGY

β-Sitosterol targets Trx/Trx1 reductase to induce apoptosis in A549 cells via ROS mediated mitochondrial dysregulation and p53 activation

(2018) Tamilselvam Rajavel et al.   Scientific Reports

Ursolic acid a promising candidate in the therapeutics of breast cancer: Current status and future implications

(2018) Javed Iqbal et al.   BIOMEDICINE & PHARMACOTHERAPY

Inhibitory effect of vanillin on RANKL-induced osteoclast formation and function through activating mitochondrial-dependent apoptosis signaling pathway

(2018) Yueqi Chen et al.   LIFE SCIENCES

Network Pharmacology to Unveil the Biological Basis of Health-Strengthening Herbal Medicine in Cancer Treatment

(2018) Jiahui Zheng et al.   Cancers

EMT and inflammation: inseparable actors of cancer progression

(2017) Meggy Suarez-Carmona et al.   Molecular Oncology

Anti-Alzheimer’s Studies on β-Sitosterol Isolated from Polygonum hydropiper L.

(2017) Muhammad Ayaz et al.   Frontiers in Pharmacology

Glioma and microglia, a double entendre

(2016) Korneel Grauwet et al.   NATURE IMMUNOLOGY

LINC01225 promotes occurrence and metastasis of hepatocellular carcinoma in an epidermal growth factor receptor-dependent pathway

(2016) X Wang et al.   Cell Death & Disease

Molecular Role of EGFR-MAPK Pathway in Patchouli Alcohol-Induced Apoptosis and Cell Cycle Arrest on A549 CellsIn VitroandIn Vivo

(2016) XinGang Lu et al.   Biomed Research International

Therapeutic Applications of Herbal Medicines for Cancer Patients

(2013) Shu-Yi Yin et al.   Evidence-based Complementary and Alternative Medicine

Chemopreventive potential of β-Sitosterol in experimental colon cancer model - an In vitro and In vivo study

(2010) Albert A Baskar et al.   BMC Complementary and Alternative Medicine