Network Pharmacology to Unveil the Biological Basis of Health-Strengthening Herbal Medicine in Cancer Treatment

Chemical genomics reveals inhibition of breast cancer lung metastasis by Ponatinib via c-Jun

(2018) Wei Shao et al.   Protein & Cell

Matrine Is Identified as a Novel Macropinocytosis Inducer by a Network Target Approach

(2018) Bo Zhang et al.   Frontiers in Pharmacology

Elements of cancer immunity and the cancer–immune set point

(2017) Daniel S. Chen et al.   NATURE

Identification of the anti-tumor activity and mechanisms of nuciferine through a network pharmacology approach

(2016) Quan Qi et al.   ACTA PHARMACOLOGICA SINICA

Therapeutic efficacy of Traditional Chinese medicine, “Kuan-Sin-Yin”, in patients undergoing chemotherapy for advanced colon cancer – A controlled trial

(2016) Tsai-Ju Chien et al.   COMPLEMENTARY THERAPIES IN MEDICINE

Understanding Tumor-Antigen Presentation in the New Era of Cancer Immunotherapy

(2016) Daniela Cerezo-Wallis et al.   CURRENT PHARMACEUTICAL DESIGN

Antigen processing and immune regulation in the response to tumours

(2016) Emma Reeves et al.   IMMUNOLOGY

The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible

(2016) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

KEGG: new perspectives on genomes, pathways, diseases and drugs

(2016) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

Synergistic Effect and Molecular Mechanisms of Traditional Chinese Medicine on Regulating Tumor Microenvironment and Cancer Cells

(2016) Jingnan Xu et al.   Biomed Research International

PubChem Substance and Compound databases

(2015) Sunghwan Kim et al.   NUCLEIC ACIDS RESEARCH

The advantages of using traditional Chinese medicine as an adjunctive therapy in the whole course of cancer treatment instead of only terminal stage of cancer

(2015) Fanghua Qi et al.   BioScience Trends

Traditional Chinese medicine and cancer: History, present situation, and development

(2015) Jie Liu et al.   Thoracic Cancer

Traditional Chinese Medicine: A Treasured Natural Resource of Anticancer Drug Research and Development

(2014) Chao-Yun Wang et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Network Pharmacology: A Rosetta Stone for Traditional Chinese Medicine

(2014) Da Cheng Hao et al.   DRUG DEVELOPMENT RESEARCH

Effect of tumor cells and tumor microenvironment on NK-cell function

(2014) Massimo Vitale et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Application of proteomics to determine the mechanism of action of traditional Chinese medicine remedies

(2014) Yuanzhi Lao et al.   JOURNAL OF ETHNOPHARMACOLOGY

A novel network pharmacology approach to analyse traditional herbal formulae: the Liu-Wei-Di-Huang pill as a case study

(2014) Xujun Liang et al.   Molecular BioSystems

Dynamic microbe and molecule networks in a mouse model of colitis-associated colorectal cancer

(2014) Xujun Liang et al.   Scientific Reports

Exploring the Ligand-Protein Networks in Traditional Chinese Medicine: Current Databases, Methods, and Applications

(2013) Mingzhu Zhao et al.   Evidence-based Complementary and Alternative Medicine

DrugBank 4.0: shedding new light on drug metabolism

(2013) Vivian Law et al.   NUCLEIC ACIDS RESEARCH

Imbalanced network biomarkers for traditional Chinese medicine Syndrome in gastritis patients

(2013) Rui Li et al.   Scientific Reports

Evidence-Based ZHENG: A Traditional Chinese Medicine Syndrome

(2012) Shi-Bing Su et al.   Evidence-based Complementary and Alternative Medicine

Tumor Microenvironment Varies under Different TCMZHENGModels and Correlates with Treatment Response to Herbal Medicine

(2012) Zhen Chen et al.   Evidence-based Complementary and Alternative Medicine

Database resources of the National Center for Biotechnology Information

(2012)   NUCLEIC ACIDS RESEARCH

Versatile pathway-centric approach based on high-throughput sequencing to anticancer drug discovery

(2012) H. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modularity-based credible prediction of disease genes and detection of disease subtypes on the phenotype-gene heterogeneous network

(2011) Xin Yao et al.   BMC Systems Biology

Antitumor activity of total paeony glycoside against human chronic myelocytic leukemia K562 cell lines in vitro and in vivo

(2011) Hui-Yu Xu et al.   MEDICAL ONCOLOGY

Impact of high-throughput screening in biomedical research

(2011) Ricardo Macarron et al.   NATURE REVIEWS DRUG DISCOVERY

MINT, the molecular interaction database: 2012 update

(2011) Luana Licata et al.   NUCLEIC ACIDS RESEARCH

The IntAct molecular interaction database in 2012

(2011) S. Kerrien et al.   NUCLEIC ACIDS RESEARCH

ChEMBL: a large-scale bioactivity database for drug discovery

(2011) A. Gaulton et al.   NUCLEIC ACIDS RESEARCH

Cytoscape 2.8: new features for data integration and network visualization

(2010) M. E. Smoot et al.   BIOINFORMATICS

The Role of Traditional Chinese Herbal Medicines in Cancer Therapy – from TCM Theory to Mechanistic Insights

(2010) W. Hsiao et al.   PLANTA MEDICA

Network-Based Relating Pharmacological and Genomic Spaces for Drug Target Identification

(2010) Shiwen Zhao et al.   PLoS One

A new dawn for the use of traditional Chinese medicine in cancer therapy

(2009) Harendra S Parekh et al.   Molecular Cancer

Network-based global inference of human disease genes

(2008) Xuebing Wu et al.   Molecular Systems Biology

Network pharmacology: the next paradigm in drug discovery

(2008) Andrew L Hopkins   Nature Chemical Biology

Human Protein Reference Database--2009 update

(2008) T. S. Keshava Prasad et al.   NUCLEIC ACIDS RESEARCH