Molecular Mechanism of β-Sitosterol and its Derivatives in Tumor Progression
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Title
Molecular Mechanism of β-Sitosterol and its Derivatives in Tumor Progression
Authors
Keywords
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Journal
Frontiers in Oncology
Volume 12, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2022-06-08
DOI
10.3389/fonc.2022.926975
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Note: Only part of the references are listed.- Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2021) Hyuna Sung et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Targeting cell-cycle machinery in cancer
- (2021) Jan M. Suski et al. CANCER CELL
- Imidazole‐modified C 6 ‐chitosan derivatives used to extract β‐sitosterol from edible oil samples with a microwave‐assisted solid phase extraction method
- (2021) Yunliang Dai et al. JOURNAL OF SEPARATION SCIENCE
- ER-Mitochondria Calcium Flux by β-Sitosterol Promotes Cell Death in Ovarian Cancer
- (2021) Hyocheol Bae et al. Antioxidants
- Immunomodulatory Effects of a Concoction of Natural Bioactive Compounds—Mechanistic Insights
- (2021) Vani Gangwar et al. Biomedicines
- Targeting Proliferating Cell Nuclear Antigen (PCNA) as an Effective Strategy to Inhibit Tumor Cell Proliferation
- (2020) Miriana Cardano et al. CURRENT CANCER DRUG TARGETS
- Targeting MAPK Signaling in Cancer: Mechanisms of Drug Resistance and Sensitivity
- (2020) Shannon Lee et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Dietary β-sitosterol regulates serum lipid level and improves immune function, antioxidant status, and intestinal morphology in broilers
- (2020) Yefei Cheng et al. POULTRY SCIENCE
- β-Sitosterol Protects against Myocardial Ischemia/Reperfusion Injury via Targeting PPARγ/NF-κB Signalling
- (2020) Fengxia Lin et al. Evidence-based Complementary and Alternative Medicine
- β-Sitosterol Reverses Multidrug Resistance via BCRP Suppression by Inhibiting the p53–MDM2 Interaction in Colorectal Cancer
- (2020) Ziyuan Wang et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- β‐Sitosterol‐assisted silver nanoparticles activates Nrf2 and triggers mitochondrial apoptosis via oxidative stress in human hepatocellular cancer cell line
- (2020) Kathiswar Raj R et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
- A Potential Anti-cancer Compound Separated from the Chloroform Extract of the Chinese Medicine Formula Shenqi San
- (2020) Lu Shi et al. Current Medical Science
- Phytosterols: Targeting Neuroinflammation in Neurodegeneration
- (2020) Raju Dash et al. CURRENT PHARMACEUTICAL DESIGN
- Isolation of Oxyberberine and β-Sitosterol from Berberis lycium Royle Root Bark Extract and In Vitro Cytotoxicity against Liver and Lung Cancer Cell Lines
- (2020) Muhammad Asad Anwar et al. Evidence-based Complementary and Alternative Medicine
- NF-κB inhibitors in treatment and prevention of lung cancer
- (2020) Rajan Radha Rasmi et al. BIOMEDICINE & PHARMACOTHERAPY
- Assessments of in vitro and in vivo antineoplastic potentials of β-sitosterol-loaded PEGylated niosomes against hepatocellular carcinoma
- (2020) Raquibun Nisha et al. JOURNAL OF LIPOSOME RESEARCH
- Biological effects of an oxyphytosterol generated by β-Sitosterol ozonization
- (2020) Bianca S. Takayasu et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Corrigendum: β-Sitosterol and Gemcitabine Exhibit Synergistic Anti-Pancreatic Cancer Activity by Modulating Apoptosis and Inhibiting Epithelial–Mesenchymal Transition by Deactivating Akt/GSK-3β Signaling
- (2020) Zhang-qi Cao et al. Frontiers in Pharmacology
- β-Sitosterol and Gemcitabine Exhibit Synergistic Anti-pancreatic Cancer Activity by Modulating Apoptosis and Inhibiting Epithelial–Mesenchymal Transition by Deactivating Akt/GSK-3β Signaling
- (2019) Zhang-qi Cao et al. Frontiers in Pharmacology
- Betulinic acid induces apoptosis and inhibits metastasis of human colorectal cancer cells in vitro and in vivo
- (2019) Anqi Zeng et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Inhibition of mitochondrial respiration prevents BRAF-mutant melanoma brain metastasis
- (2019) Terje Sundstrøm et al. Acta Neuropathologica Communications
- Epigenetic silencing of genes enhanced by collective role of reactive oxygen species and MAPK signaling downstream ERK/Snail axis: Ectopic application of hydrogen peroxide repress CDH1 gene by enhanced DNA methyltransferase activity in human breast cancer
- (2019) Nibedita Pradhan et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Targeting PCNA with peptide mimetics for therapeutic purposes
- (2019) Aimee J. Horsfall et al. CHEMBIOCHEM
- Effect of β-sitosterol self-microemulsion and β-sitosterol ester with linoleic acid on lipid-lowering in hyperlipidemic mice
- (2019) Chuanxun Yuan et al. Lipids in Health and Disease
- Paederia foetida induces anticancer activity by modulating chromatin modification enzymes and altering pro-inflammatory cytokine gene expression in human prostate cancer cells
- (2019) Nibedita Pradhan et al. FOOD AND CHEMICAL TOXICOLOGY
- Effects of β-Sitosterol from Corn Silk on TGF-β1-Induced Epithelial–Mesenchymal Transition in Lung Alveolar Epithelial Cells
- (2019) Yong Joo Park et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Assessment of the hepatoprotective effect of developed lipid-polymer hybrid nanoparticles (LPHNPs) encapsulating naturally extracted β-Sitosterol against CCl4 induced hepatotoxicity in rats
- (2019) Ebtsam M. Abdou et al. Scientific Reports
- Anti-tumour effects of beta-sitosterol are mediated by AMPK/PTEN/HSP90 axis in AGS human gastric adenocarcinoma cells and xenograft mouse models
- (2018) Eun Ju Shin et al. BIOCHEMICAL PHARMACOLOGY
- Phytosterols in cancer: From molecular mechanisms to preventive and therapeutic potentials
- (2018) Francisco Blanco-Vaca et al. CURRENT MEDICINAL CHEMISTRY
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- (2018) Hayato Tada et al. Journal of Atherosclerosis and Thrombosis
- Synergistic Effect of Bioactive Anticarcinogens from Soybean on Anti-Proliferative Activity in MDA-MB-231 and MCF-7 Human Breast Cancer Cells In Vitro
- (2018) Yingying Zhu et al. MOLECULES
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- (2018) Jennifer N. Moloney et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Anticandidal activity of the extract and compounds isolated from Cyperus conglomertus Rottb
- (2018) Ghaferah H. Al-Hazmi et al. SAUDI PHARMACEUTICAL JOURNAL
- β-Sitosterol targets Trx/Trx1 reductase to induce apoptosis in A549 cells via ROS mediated mitochondrial dysregulation and p53 activation
- (2018) Tamilselvam Rajavel et al. Scientific Reports
- Treating p53 Mutant Aggregation-Associated Cancer
- (2018) Mathumai Kanapathipillai Cancers
- Apoptotic effect of a phytosterol-ingredient and its main phytosterol (β-sitosterol) in human cancer cell lines
- (2018) Andrea Alvarez-Sala et al. INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION
- Anti-breast-Cancer Activity Exerted by β-Sitosterol-d-glucoside from Sweet Potato via Upregulation of MicroRNA-10a and via the PI3K–Akt Signaling Pathway
- (2018) Heshan Xu et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Correlation between microbes and colorectal cancer: tumor apoptosis is induced by sitosterols through promoting gut microbiota to produce short-chain fatty acids
- (2018) Hang Ma et al. APOPTOSIS
- In silico and in vivo analysis to identify the antidiabetic activity of beta sitosterol in adipose tissue of high fat diet and sucrose induced type-2 diabetic experimental rats
- (2018) R. Ponnulakshmi et al. TOXICOLOGY MECHANISMS AND METHODS
- EMT Transition States during Tumor Progression and Metastasis
- (2018) Ievgenia Pastushenko et al. TRENDS IN CELL BIOLOGY
- ROS and the DNA damage response in cancer
- (2018) Upadhyayula Sai Srinivas et al. Redox Biology
- Evaluation of β-Sitosterol Loaded PLGA and PEG-PLA Nanoparticles for Effective Treatment of Breast Cancer: Preparation, Physicochemical Characterization, and Antitumor Activity
- (2018) Moses Andima et al. Pharmaceutics
- Interleukin-armed chimeric antigen receptor-modified T cells for cancer immunotherapy
- (2017) Y Huang et al. GENE THERAPY
- Synthesis and characterization of redox-sensitive heparin-β-sitosterol micelles: Their application as carriers for the pharmaceutical agent, doxorubicin, and investigation of their antimetastatic activities in vitro
- (2017) Tilahun Ayane Debele et al. Materials Science & Engineering C-Materials for Biological Applications
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- (2017) Xingchun Wang et al. ONCOLOGY REPORTS
- Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-years for 32 Cancer Groups, 1990 to 2015
- (2017) et al. JAMA Oncology
- Beta sitosterol and Daucosterol (phytosterols identified in Grewia tiliaefolia) perturbs cell cycle and induces apoptotic cell death in A549 cells
- (2017) Tamilselvam Rajavel et al. Scientific Reports
- EVALUATION OF THE ANTI-INFLAMMATORY CAPACITY OF BETA-SITOSTEROL IN RODENT ASSAYS
- (2016) Rogelio Paniagua-Pérez et al. African Journal of Traditional Complementary and Alternative Medicines
- PHYTOCHEMISTRY, CYTOTOXICITY AND APOPTOSIS STUDIES OF Β-SITOSTEROL-3-OGLUCOSIDE AND Β -AMYRIN FROM PRUNUS AFRICANA
- (2016) F. Maiyo et al. African Journal of Traditional Complementary and Alternative Medicines
- Elucidation of the anticancer potential and tubulin isotype-specific interactions of β-sitosterol
- (2016) Madhura Pradhan et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- Hematologic malignancies: newer strategies to counter the BCL-2 protein
- (2016) Abdul Shukkur Ebrahim et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Biochemical characterization and molecular dynamic simulation of β-sitosterol as a tubulin-binding anticancer agent
- (2015) Tejashree Mahaddalkar et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Apoptogenic effects of β-sitosterol glucoside fromCastanopsis indicaleaves
- (2015) Narayan Dolai et al. NATURAL PRODUCT RESEARCH
- Effect of β-sitosterol on the expression of HPV E6 and p53 in cervical carcinoma cells
- (2015) Dali Cheng et al. Wspolczesna Onkologia-Contemporary Oncology
- RAS-MAPK pathway epigenetic activation in cancer: miRNAs in action
- (2015) Julien Masliah-Planchon et al. Oncotarget
- Erratum: Generation of cancer stem-like cells through the formation of polyploid giant cancer cells
- (2014) S Zhang et al. ONCOGENE
- β-sitosterol induces G1 arrest and causes depolarization of mitochondrial membrane potential in breast carcinoma MDA-MB-231 cells
- (2013) Shanthi Sri Vundru et al. BMC Complementary and Alternative Medicine
- Reactive Oxygen Species-Mediated Activation of AMP-Activated Protein Kinase and c-Jun N-terminal Kinase Plays a Critical Role in Beta-Sitosterol-Induced Apoptosis in Multiple Myeloma U266 cells
- (2013) Song Hyo Sook et al. PHYTOTHERAPY RESEARCH
- 7α-Hydroxy-β-Sitosterol fromChisocheton tomentosusInduces Apoptosis via Dysregulation of Cellular Bax/Bcl-2 Ratio and Cell Cycle Arrest by Downregulating ERK1/2 Activation
- (2012) Mohammad Tasyriq et al. Evidence-based Complementary and Alternative Medicine
- β-Sitosterol Prevents Lipid Peroxidation and Improves Antioxidant Status and Histoarchitecture in Rats with 1,2-Dimethylhydrazine-Induced Colon Cancer
- (2012) Arul Albert Baskar et al. JOURNAL OF MEDICINAL FOOD
- Down-Regulation of CDH1 Is Associated with Expression of SNAI1 in Colorectal Adenomas
- (2012) Feride Kroepil et al. PLoS One
- Chemopreventive potential of β-Sitosterol in experimental colon cancer model - an In vitro and In vivo study
- (2010) Albert A Baskar et al. BMC Complementary and Alternative Medicine
- The paradox of cancer cell apoptosis
- (2010) Bruce et al. Frontiers in Bioscience-Landmark
- β-Sitosterol Inhibits Cell Growth and Induces Apoptosis in SGC-7901 Human Stomach Cancer Cells
- (2009) Yonghuan Zhao et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- Chemoprevention of Tumor Metastasis by Liposomal β-Sitosterol Intake
- (2008) Hiromichi Imanaka et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- β-Sitosterol induces G2/M arrest, endoreduplication, and apoptosis through the Bcl-2 and PI3K/Akt signaling pathways
- (2008) Dong-Oh Moon et al. CANCER LETTERS
- β-Sitosterol enhances tamoxifen effectiveness on breast cancer cells by affecting ceramide metabolism
- (2008) Atif B. Awad et al. MOLECULAR NUTRITION & FOOD RESEARCH
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