Recent Development of Radiofluorination of Boron Agents for Boron Neutron Capture Therapy of Tumor: Creation of 18F-Labeled C-F and B-F Linkages

Positron emission tomography molecular imaging‐based cancer phenotyping

(2022) Chentao Jin et al.   CANCER

Synthesis and Evaluation of 18F-Labeled Boramino Acids as Potential New Positron Emission Tomography Agents for Cancer Management

(2022) Liu Zhou et al.   MOLECULAR PHARMACEUTICS

Dodecaborate-Encapsulated Extracellular Vesicles with Modification of Cell-Penetrating Peptides for Enhancing Macropinocytotic Cellular Uptake and Biological Activity in Boron Neutron Capture Therapy

(2022) Shiori Hirase et al.   MOLECULAR PHARMACEUTICS

Metabolic characteristics of [18F]fluoroboronotyrosine (FBY) PET in malignant brain tumors

(2022) Ziren Kong et al.   NUCLEAR MEDICINE AND BIOLOGY

Evaluation of 3-Borono-l-Phenylalanine as a Water-Soluble Boron Neutron Capture Therapy Agent

(2022) Naoya Kondo et al.   Pharmaceutics

LAT1, a novel pharmacological target for the treatment of glioblastoma

(2022) Natalia Cappoli et al.   BIOCHEMICAL PHARMACOLOGY

Fluorine-containing drugs approved by the FDA in 2021

(2022) Jingrui He et al.   CHINESE CHEMICAL LETTERS

Exploring the Biological and Physical Basis of Boron Neutron Capture Therapy (BNCT) as a Promising Treatment Frontier in Breast Cancer

(2022) Danushka Seneviratne et al.   Cancers

Polyglycerol Functionalized 10 B Enriched Boron Carbide Nanoparticle as an Effective Bimodal Anticancer Nanosensitizer for Boron Neutron Capture and Photothermal Therapies

(2022) Yuquan Wang et al.   Small

Facile C−F Bond Activation Approach to FAMT‐Based Difluoromethyl‐BNCT Drug Candidates

(2021) Akitaka Yokawa et al.   HELVETICA CHIMICA ACTA

18F-Boramino acid PET/CT in healthy volunteers and glioma patients

(2021) Zhu Li et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

First-in-human study of an 18F-labeled boramino acid: a new class of PET tracers

(2021) Xiaoli Lan et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Construction of Boronophenylalanine-Loaded Biodegradable Periodic Mesoporous Organosilica Nanoparticles for BNCT Cancer Therapy

(2021) Fuyuhiko Tamanoi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Boron clusters as breast cancer therapeutics

(2021) N. Murphy et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Boron-enriched polyvinyl-alcohol/boric-acid nanoparticles for boron neutron capture therapy

(2021) Wei-Jen Chan et al.   Nanomedicine

Biodistribution and radiation dosimetry of D-isomer of 4-borono-2-[18F]fluoro-phenylalanine: A comparative PET/CT study with L-isomer in healthy human volunteers

(2021) Qiao Yang et al.   NUCLEAR MEDICINE AND BIOLOGY

Boron Neutron Capture Therapy: A Review of Clinical Applications

(2021) Timothy D. Malouff et al.   Frontiers in Oncology

Chemical Aspects of Human and Environmental Overload with Fluorine

(2021) Jianlin Han et al.   CHEMICAL REVIEWS

The impact of dietary macronutrient intake on cognitive function and the brain

(2021) Anne-Katrin Muth et al.   CLINICAL NUTRITION

Theranostics in Boron Neutron Capture Therapy

(2021) Wolfgang A. G. Sauerwein et al.   Life-Basel

Amino acid transporter LAT1 (SLC7A5) as a molecular target for cancer diagnosis and therapeutics

(2021) Yoshikatsu Kanai   PHARMACOLOGY & THERAPEUTICS

Boron rich nanotube drug carrier system is suited for boron neutron capture therapy

(2021) Fabian Heide et al.   Scientific Reports

Reaction of [18F]Fluoride at Heteroatoms and Metals for Imaging of Peptides and Proteins by Positron Emission Tomography

(2021) Kymberley R. Scroggie et al.   Frontiers in Chemistry

Interaction of Adenosine, Modified Using Carborane Clusters, with Ovarian Cancer Cells: A New Anticancer Approach against Chemoresistance

(2021) Katarzyna Bednarska-Szczepaniak et al.   Cancers

Polymer-Coated Nanoparticles for Therapeutic and Diagnostic Non-10B Enriched Polymer-Coated Boron Carbon Oxynitride (BCNO) Nanoparticles as Potent BNCT Drug

(2021) Chen-Wei Chiang et al.   Nanomaterials

Using salvage Boron Neutron Capture Therapy (BNCT) for recurrent malignant brain tumors in Taiwan

(2020) Tien-Li Lan et al.   APPLIED RADIATION AND ISOTOPES

Boron Chemistry for Medical Applications

(2020) Fayaz Ali et al.   MOLECULES

Electrosprayed chitosan/alginate/polyvinyl alcohol nanoparticles as boric acid carriers for 10Boron neutron capture therapy

(2020) Wei-Cheng Wu et al.   Nanomedicine

L-Type amino acid transporter 1 as a target for drug delivery

(2020) Elena Puris et al.   PHARMACEUTICAL RESEARCH

Contribution of Organofluorine Compounds to Pharmaceuticals

(2020) Munenori Inoue et al.   ACS Omega

Research Progress of 18F Labeled Small Molecule Positron Emission Tomography (PET) Imaging Agents

(2020) Mingliang Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Difference in BPA uptake between glioma stem-like cells and their cancerous cells

(2020) Fumiyo Yoshida et al.   APPLIED RADIATION AND ISOTOPES

The importance of optimal ROIs delineation for FBPA-PET before BNCT

(2020) Yi-Wen Lo et al.   APPLIED RADIATION AND ISOTOPES

Nucleophilic Synthesis of 6-l-[18F]FDOPA. Is Copper-Mediated Radiofluorination the Answer?

(2020) Raisa N. Krasikova   MOLECULES

Antibody-Based Receptor Targeting Using an Fc-Binding Peptide-Dodecaborate Conjugate and Macropinocytosis Induction for Boron Neutron Capture Therapy

(2020) Ikuhiko Nakase et al.   ACS Omega

Synthesis of enriched boron nitride nanocrystals: A potential element for biomedical applications

(2020) Pervaiz Ahmad et al.   APPLIED RADIATION AND ISOTOPES

Translational Boron Neutron Capture Therapy (BNCT) studies for the treatment of tumors in lung

(2019) V.A. Trivillin et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

4-Borono-2-18F-fluoro-l-phenylalanine PET for boron neutron capture therapy-oriented diagnosis: overview of a quarter century of research

(2019) Kiichi Ishiwata   ANNALS OF NUCLEAR MEDICINE

Electroporation optimizes the uptake of boron-10 by tumor for boron neutron capture therapy (BNCT) mediated by GB-10: a boron biodistribution study in the hamster cheek pouch oral cancer model

(2019) Marcela A. Garabalino et al.   RADIATION AND ENVIRONMENTAL BIOPHYSICS

Boron neutron capture therapy (BNCT): a unique role in radiotherapy with a view to entering the accelerator-based BNCT era

(2019) Minoru Suzuki   International Journal of Clinical Oncology

Boron-Nanoparticle-Loaded Folic-Acid-Functionalized Liposomes to Achieve Optimum Boron Concentration for Boron Neutron Capture Therapy of Cancer

(2019) Ajay Singh et al.   Journal of Biomedical Nanotechnology

Therapeutic Efficacy and Radiobiological Effects of Boric Acid-mediated BNCT in a VX2 Multifocal Liver Tumor-bearing Rabbit Model

(2019) YI-HSUAN HUNG et al.   ANTICANCER RESEARCH

Diagnostic Performance and Prognostic Value of PET/CT with Different Tracers for Brain Tumors: A Systematic Review of Published Meta-Analyses

(2019) Giorgio Treglia et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A Metabolically Stable Boron-Derived Tyrosine Serves as a Theranostic Agent for Positron Emission Tomography Guided Boron Neutron Capture Therapy

(2019) Jiyuan Li et al.   BIOCONJUGATE CHEMISTRY

Development of theranostic active-targeting boron-containing gold nanoparticles for boron neutron capture therapy (BNCT)

(2019) Chun-Yi Wu et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Evaluation of the total distribution volume of 18F-FBPA in normal tissues of healthy volunteers by non-compartmental kinetic modeling

(2019) Victor Romanov et al.   ANNALS OF NUCLEAR MEDICINE

Boron agents for neutron capture therapy

(2019) Kuan Hu et al.   COORDINATION CHEMISTRY REVIEWS

Fluorine-18: A radionuclide with diverse range of radiochemistry and synthesis strategies for target based PET diagnosis

(2019) Nerella Sridhar Goud et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Reliable radiosynthesis of 4-[10B]borono-2-[18F]fluoro-l-phenylalanine with quality assurance for boron neutron capture therapy-oriented diagnosis

(2018) Kiichi Ishiwata et al.   ANNALS OF NUCLEAR MEDICINE

Non-invasive estimation of 10 B-4-borono-L-phenylalanine-derived boron concentration in tumors by PET using 4-borono-2-18 F-fluoro-phenylalanine

(2018) Mitsuyoshi Yoshimoto et al.   CANCER SCIENCE

Glucose transporters in cancer - from tumor cells to the tumor microenvironment

(2018) Pierre-Benoit Ancey et al.   FEBS Journal

Dynamic changes in 18F-borono-L-phenylalanine uptake in unresectable, advanced, or recurrent squamous cell carcinoma of the head and neck and malignant melanoma during boron neutron capture therapy patient selection

(2018) Takahiro Morita et al.   Radiation Oncology

18F-Labelled catecholamine type radiopharmaceuticals in the diagnosis of neurodegenerative diseases and neuroendocrine tumours: approaches to synthesis and development prospects

(2018) S Z Vatsadze et al.   RUSSIAN CHEMICAL REVIEWS

Synthesis and characterization of boron fenbufen and its F-18 labeled homolog for boron neutron capture therapy of COX-2 overexpressed cholangiocarcinoma

(2017) Chun-Nan Yeh et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

On the applicability of [18F]FBPA to predict L-BPA concentration after amino acid preloading in HuH-7 liver tumor model and the implication for liver boron neutron capture therapy

(2017) Catrin Grunewald et al.   NUCLEAR MEDICINE AND BIOLOGY

Applications of Fluorine in Medicinal Chemistry

(2015) Eric P. Gillis et al.   JOURNAL OF MEDICINAL CHEMISTRY

Critical review, with an optimistic outlook, on Boron Neutron Capture Therapy (BNCT)

(2013) Raymond L. Moss   APPLIED RADIATION AND ISOTOPES

Fluorine-18 Labeled Amino Acids for Oncologic Imaging with Positron Emission Tomography

(2013) Chaofeng Huang et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Large neutral amino acids: dietary effects on brain neurochemistry and function

(2012) John D. Fernstrom   AMINO ACIDS

18F-FDG PET/CT for Image-Guided and Intensity-Modulated Radiotherapy

(2009) E. C. Ford et al.   JOURNAL OF NUCLEAR MEDICINE

6-L-18F-Fluorodihydroxyphenylalanine PET in Neuroendocrine Tumors: Basic Aspects and Emerging Clinical Applications

(2008) P. L. Jager et al.   JOURNAL OF NUCLEAR MEDICINE

Molecular Imaging of Hypoxia

(2008) K. A. Krohn et al.   JOURNAL OF NUCLEAR MEDICINE

Fluorination in Medicinal Chemistry: Methods, Strategies, and Recent Developments

(2008) Kenneth L. Kirk   ORGANIC PROCESS RESEARCH & DEVELOPMENT