Evaluation of 3-Borono-l-Phenylalanine as a Water-Soluble Boron Neutron Capture Therapy Agent

Designation Products: Boron Neutron Capture Therapy for Head and Neck Carcinoma

(2021) Hitoshi Kanno et al.   ONCOLOGIST

Amino acid transporter LAT1 (SLC7A5) as a molecular target for cancer diagnosis and therapeutics

(2021) Yoshikatsu Kanai   PHARMACOLOGY & THERAPEUTICS

Improvement in aqueous solubility of achiral symmetric cyclofenil by modification to a chiral asymmetric analog

(2021) Junki Morimoto et al.   Scientific Reports

Poly(vinyl alcohol) boosting therapeutic potential of p-boronophenylalanine in neutron capture therapy by modulating metabolism

(2020) Takahiro Nomoto et al.   Science Advances

JPH203, a newly developed anti-cancer drug, shows a preincubation inhibitory effect on L-type amino acid transporter 1 function

(2020) Kentaro Okunushi et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

4-Borono-2-18F-fluoro-l-phenylalanine PET for boron neutron capture therapy-oriented diagnosis: overview of a quarter century of research

(2019) Kiichi Ishiwata   ANNALS OF NUCLEAR MEDICINE

A Metabolically Stable Boron-Derived Tyrosine Serves as a Theranostic Agent for Positron Emission Tomography Guided Boron Neutron Capture Therapy

(2019) Jiyuan Li et al.   BIOCONJUGATE CHEMISTRY

Insights into the Structure, Function, and Ligand Discovery of the Large Neutral Amino Acid Transporter 1, LAT1

(2018) Natesh Singh et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Impact of oxygen status on 10B-BPA uptake into human glioblastoma cells, referring to significance in boron neutron capture therapy

(2018) Yuki Wada et al.   JOURNAL OF RADIATION RESEARCH

CD44 variant inhibits insulin secretion in pancreatic β cells by attenuating LAT1-mediated amino acid uptake

(2018) Nana Kobayashi et al.   Scientific Reports

The LAT1 inhibitor JPH203 reduces growth of thyroid carcinoma in a fully immunocompetent mouse model

(2018) Pascal Häfliger et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Reevaluating the Substrate Specificity of the L-Type Amino Acid Transporter (LAT1)

(2018) Huan-Chieh Chien et al.   JOURNAL OF MEDICINAL CHEMISTRY

Small Molecular Weight Aldose (d-Glucose) and Basic Amino Acids (l-Lysine, l-Arginine) Increase the Occurrence of PAHs in Grilled Pork Sausages

(2018) Wen Nie et al.   MOLECULES

Improvement in Aqueous Solubility of Retinoic Acid Receptor (RAR) Agonists by Bending the Molecular Structure

(2016) Michiaki Hiramatsu et al.   Chemistry-An Asian Journal

Boronophenylalanine, a boron delivery agent for boron neutron capture therapy, is transported by ATB0,+, LAT1 and LAT2

(2015) Printip Wongthai et al.   CANCER SCIENCE

A Highly Stereoselective and Scalable Synthesis of l-allo-Enduracididine

(2015) William Craig et al.   ORGANIC LETTERS

General Methods for Synthesis ofN-Methyliminodiacetic Acid Boronates from Unstableortho-Phenolboronic Acids

(2014) Su-Jin Ahn et al.   ADVANCED SYNTHESIS & CATALYSIS

Critical review, with an optimistic outlook, on Boron Neutron Capture Therapy (BNCT)

(2013) Raymond L. Moss   APPLIED RADIATION AND ISOTOPES

Boron neutron capture therapy for advanced salivary gland carcinoma in head and neck

(2013) Teruhito Aihara et al.   International Journal of Clinical Oncology

In Vitro Studies on Stability of L-p-boronophenylalanine–fructose Complex (BPA-F)

(2011) Sami HEIKKINEN et al.   JOURNAL OF RADIATION RESEARCH

Synthesis and properties of MIDA boronate containing aromatic amino acids: New peptide building blocks

(2011) Neil Colgin et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Boron neutron capture therapy for newly diagnosed glioblastoma multiforme: an assessment of clinical potential

(2010) K Sköld et al.   BRITISH JOURNAL OF RADIOLOGY

L-Amino Acid Transporter-1 and Boronophenylalanine-Based Boron Neutron Capture Therapy of Human Brain Tumors

(2009) A. Detta et al.   CANCER RESEARCH

Boron neutron capture therapy (BNCT) for glioblastoma multiforme: A phase II study evaluating a prolonged high-dose of boronophenylalanine (BPA)

(2008) Roger Henriksson et al.   RADIOTHERAPY AND ONCOLOGY