Nucleophilic Synthesis of 6-l-[18F]FDOPA. Is Copper-Mediated Radiofluorination the Answer?

Synthesis of high-molar-activity [18F]6-fluoro-l-DOPA suitable for human use via Cu-mediated fluorination of a BPin precursor

(2020) Andrew V. Mossine et al.   Nature Protocols

Copper-mediated late-stage radiofluorination: five years of impact on preclinical and clinical PET imaging

(2020) Jay S. Wright et al.   Clinical and Translational Imaging

MCR Scaffolds Get Hotter with 18F-Labeling

(2019) Tryfon Zarganes-Tzitzikas et al.   MOLECULES

Use of capillary electrophoresis for the determination of impurities in preparations of fluorine-18 labelled PET radiopharmaceuticals

(2019) Dmitrii Antuganov et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Alcohol-Supported Cu-Mediated 18F-Fluorination of Iodonium Salts under “Minimalist” Conditions

(2019) Victoriya V. Orlovskaya et al.   MOLECULES

Update on amino acid PET of brain tumours

(2018) Karl-Josef Langen et al.   CURRENT OPINION IN NEUROLOGY

Hypervalent aryliodine compounds as precursors for radiofluorination

(2018) Victor W. Pike   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Chemistry for Positron Emission Tomography: Recent Advances in 11C-, 18F-, 13N- and 15O-labeling Reactions

(2018) Xiaoyun Deng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Mediated Radiofluorination of Aryl Pinacolboronate Esters: A Straightforward Protocol by Using Pyridinium Sulfonates

(2018) Dmitrii Antuganov et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Base/Cryptand/Metal-Free Automated Nucleophilic Radiofluorination of [18 F]FDOPA from Iodonium Salts: Importance of Hydrogen Carbonate Counterion

(2018) Aurélie Maisonial-Besset et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Guideline for PET/CT imaging of neuroendocrine neoplasms with 68Ga-DOTA-conjugated somatostatin receptor targeting peptides and 18F–DOPA

(2017) Murat Fani Bozkurt et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Vacuum ultraviolet photon-mediated production of [18F]F2

(2017) Anna Krzyczmonik et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Derisking the Cu-Mediated 18F-Fluorination of Heterocyclic Positron Emission Tomography Radioligands

(2017) Nicholas J. Taylor et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Practical Method for the Preparation of 18F-Labeled Aromatic Amino Acids from Nucleophilic [18F]Fluoride and Stannyl Precursors for Electrophilic Radiohalogenation

(2017) Fadi Zarrad et al.   MOLECULES

Evaluation of two nucleophilic syntheses routes for the automated synthesis of 6-[18F]fluoro-l-DOPA

(2017) Marc Pretze et al.   NUCLEAR MEDICINE AND BIOLOGY

Production of diverse PET probes with limited resources: 2418F-labeled compounds prepared with a single radiosynthesizer

(2017) Jeffrey Collins et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A revisit to quantitative PET with 18F-FDOPA of high specific activity using a high-resolution condition in view of application to regenerative therapy

(2016) Go Akamatsu et al.   ANNALS OF NUCLEAR MEDICINE

Automated synthesis of 4-[ 18 F]fluoroanisole, [ 18 F]DAA1106 and 4-[ 18 F]FPhe using Cu-mediated radiofluorination under “minimalist” conditions

(2016) Johannes Zischler et al.   APPLIED RADIATION AND ISOTOPES

Enhanced copper-mediated 18F-fluorination of aryl boronic esters provides eight radiotracers for PET applications

(2016) Sean Preshlock et al.   CHEMICAL COMMUNICATIONS

18F-Labeling of Arenes and Heteroarenes for Applications in Positron Emission Tomography

(2016) Sean Preshlock et al.   CHEMICAL REVIEWS

18F-DOPA: the versatile radiopharmaceutical

(2016) David Taïeb et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Response Assessment in Neuro-Oncology working group and European Association for Neuro-Oncology recommendations for the clinical use of PET imaging in gliomas

(2016) Nathalie L. Albert et al.   NEURO-ONCOLOGY

Copper-Mediated Radiofluorination of Arylstannanes with [18F]KF

(2016) Katarina J. Makaravage et al.   ORGANIC LETTERS

Amino Acid PET – An Imaging Option to Identify Treatment Response, Posttherapeutic Effects, and Tumor Recurrence?

(2016) Norbert Galldiks et al.   Frontiers in Neurology

Copper-Mediated Aromatic Radiofluorination Revisited: Efficient Production of PET Tracers on a Preparative Scale

(2015) Boris D. Zlatopolskiy et al.   CHEMISTRY-A EUROPEAN JOURNAL

Automated production at the curie level of no-carrier-added 6-[18F]fluoro-l-dopa and 2-[18F]fluoro-l-tyrosine on a FASTlab synthesizer

(2015) C. Lemaire et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

[18F]6-fluoro-3,4-dihydroxy-l-phenylalanine - recent modern syntheses for an elusive radiotracer

(2015) Richard Edwards et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Increasing feasibility and utility of 18 F-FDOPA PET for the management of glioma

(2015) Christopher Bell et al.   NUCLEAR MEDICINE AND BIOLOGY

Synthesis of [18F]Arenes via the Copper-Mediated [18F]Fluorination of Boronic Acids

(2015) Andrew V. Mossine et al.   ORGANIC LETTERS

Methods for the synthesis of fluorine-18-labeled aromatic amino acids, radiotracers for positron emission tomography (PET)

(2015) V. V. Orlovskaya et al.   RUSSIAN CHEMICAL BULLETIN

A General Copper-Mediated Nucleophilic18F Fluorination of Arenes

(2014) Matthew Tredwell et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fluorine-18 Radiochemistry, Labeling Strategies and Synthetic Routes

(2014) Orit Jacobson et al.   BIOCONJUGATE CHEMISTRY

Role of18F-FDOPA PET/CT imaging in endocrinology

(2014) Prasanna Santhanam et al.   CLINICAL ENDOCRINOLOGY

Radiosyntheses using Fluorine-18: The Art and Science of Late Stage Fluorination

(2014) Erin Cole et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Convenient Synthesis of Diaryliodonium Salts for the Production of [18F]F-DOPA

(2014) Richard Edwards et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

In Vivo Biodistribution of No-Carrier-Added 6-18F-Fluoro-3,4-Dihydroxy-L-Phenylalanine (18F-DOPA), Produced by a New Nucleophilic Substitution Approach, Compared with Carrier-Added 18F-DOPA, Prepared by Conventional Electrophilic Substitution

(2014) W.-J. Kuik et al.   JOURNAL OF NUCLEAR MEDICINE

Neuroimaging in Parkinson disease: from research setting to clinical practice

(2014) Marios Politis   Nature Reviews Neurology

Copper-Catalyzed [18F]Fluorination of (Mesityl)(aryl)iodonium Salts

(2014) Naoko Ichiishi et al.   ORGANIC LETTERS

Late-stage [18F]fluorination: new solutions to old problems

(2014) Allen F. Brooks et al.   Chemical Science

6-[18F]Fluoro-L-DOPA: A Well-Established Neurotracer with Expanding Application Spectrum and Strongly Improved Radiosyntheses

(2014) M. Pretze et al.   Biomed Research International

[18F]Fluorination of an arylboronic ester using [18F]selectfluor bis(triflate): application to 6-[18F]fluoro-l-DOPA

(2013) Ida S. R. Stenhagen et al.   CHEMICAL COMMUNICATIONS

Methods for11C- and18F-labelling of amino acids and derivatives for positron emission tomography imaging

(2013) Johannes Ermert et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Production at the Curie Level of No-Carrier-Added 6-18F-Fluoro-L-Dopa

(2013) L. C. Libert et al.   JOURNAL OF NUCLEAR MEDICINE

Cu(OTf)2-Mediated Fluorination of Aryltrifluoroborates with Potassium Fluoride

(2013) Yingda Ye et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cu-Catalyzed Fluorination of Diaryliodonium Salts with KF

(2013) Naoko Ichiishi et al.   ORGANIC LETTERS

High beam current operation of a PETtraceTM cyclotron for 18F− production

(2012) S. Eberl et al.   APPLIED RADIATION AND ISOTOPES

Multimodal Magnetic Resonance Imaging and 18F-L-Dihydroxyphenylalanine Positron Emission Tomography in Early Characterization of Pseudoresponse and Nonenhancing Tumor Progression in a Pediatric Patient With Malignant Transformation of Ganglioglioma Treated With Bevacizumab

(2012) Giovanni Morana et al.   JOURNAL OF CLINICAL ONCOLOGY

A Fluoride-Derived Electrophilic Late-Stage Fluorination Reagent for PET Imaging

(2011) E. Lee et al.   SCIENCE

Recent advances in PET imaging for evaluation of Parkinson’s disease

(2010) Chrissa Sioka et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Correlation of 6-18F-Fluoro-L-Dopa PET Uptake with Proliferation and Tumor Grade in Newly Diagnosed and Recurrent Gliomas

(2010) B. J. Fueger et al.   JOURNAL OF NUCLEAR MEDICINE

Copper-Promoted Carbon-Heteroatom Bond Cross-Coupling with Boronic Acids and Derivatives

(2010) Jennifer Qiao et al.   SYNTHESIS-STUTTGART

Three-Step, "One-Pot" Radiosynthesis of 6-Fluoro-3,4-Dihydroxy-L-Phenylalanine by Isotopic Exchange

(2009) F. M. Wagner et al.   JOURNAL OF NUCLEAR MEDICINE

18F-FDOPA: A Multiple-Target Molecule

(2009) H. Minn et al.   JOURNAL OF NUCLEAR MEDICINE

Chemistry with [18F]Fluoride Ion

(2008) Lisheng Cai et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

6-L-18F-Fluorodihydroxyphenylalanine PET in Neuroendocrine Tumors: Basic Aspects and Emerging Clinical Applications

(2008) P. L. Jager et al.   JOURNAL OF NUCLEAR MEDICINE

Electrophilic synthesis of 6-[18F]fluoro-L-DOPA using post-target produced [18F]F2

(2008) Sarita Forsback et al.   RADIOCHIMICA ACTA