4-Borono-2-18F-fluoro-l-phenylalanine PET for boron neutron capture therapy-oriented diagnosis: overview of a quarter century of research

Reliable radiosynthesis of 4-[10B]borono-2-[18F]fluoro-l-phenylalanine with quality assurance for boron neutron capture therapy-oriented diagnosis

(2018) Kiichi Ishiwata et al.   ANNALS OF NUCLEAR MEDICINE

Non-invasive estimation of 10 B-4-borono-L-phenylalanine-derived boron concentration in tumors by PET using 4-borono-2-18 F-fluoro-phenylalanine

(2018) Mitsuyoshi Yoshimoto et al.   CANCER SCIENCE

Dynamic changes in 18F-borono-L-phenylalanine uptake in unresectable, advanced, or recurrent squamous cell carcinoma of the head and neck and malignant melanoma during boron neutron capture therapy patient selection

(2018) Takahiro Morita et al.   Radiation Oncology

Evaluation of D-isomers of 4-borono-2-18F-fluoro-phenylalanine and O-11C-methyl-tyrosine as brain tumor imaging agents: a comparative PET study with their L-isomers in rat brain glioma

(2018) Masakatsu Kanazawa et al.   EJNMMI Research

Preliminary feasibility study on differential diagnosis between radiation-induced cerebral necrosis and recurrent brain tumor by means of [18F]fluoro-borono-phenylalanine PET/CT

(2018) Rouaa Beshr et al.   ANNALS OF NUCLEAR MEDICINE

Quantification of O-(2-[18F]fluoroethyl)-L-tyrosine kinetics in glioma

(2018) Thomas Koopman et al.   EJNMMI Research

On the applicability of [18F]FBPA to predict L-BPA concentration after amino acid preloading in HuH-7 liver tumor model and the implication for liver boron neutron capture therapy

(2017) Catrin Grunewald et al.   NUCLEAR MEDICINE AND BIOLOGY

Relationship between the uptake of 18F-borono-L-phenylalanine and L-[methyl-11C] methionine in head and neck tumors and normal organs

(2017) Yoshiaki Watanabe et al.   Radiation Oncology

Assessment of 10B concentration in boron neutron capture therapy: potential of image-guided therapy using 18FBPA PET

(2016) Eku Shimosegawa et al.   ANNALS OF NUCLEAR MEDICINE

In vivo spatial correlation between 18 F-BPA and 18 F-FDG uptakes in head and neck cancer

(2016) Kazuma Kobayashi et al.   APPLIED RADIATION AND ISOTOPES

Preloading with L-BPA, L-tyrosine and L-DOPA enhances the uptake of [ 18 F]FBPA in human and mouse tumour cell lines

(2016) Bettina Wingelhofer et al.   APPLIED RADIATION AND ISOTOPES

Comparison of the pharmacokinetics between L-BPA and L-FBPA using the same administration dose and protocol: a validation study for the theranostic approach using [18F]-L-FBPA positron emission tomography in boron neutron capture therapy

(2016) Tsubasa Watanabe et al.   BMC CANCER

18F-FBPA as a tumor-specific probe of L-type amino acid transporter 1 (LAT1): a comparison study with 18F-FDG and 11C-Methionine PET

(2016) Tadashi Watabe et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Boron Neutron Capture Therapy for Malignant Brain Tumors

(2016) Shin-Ichi MIYATAKE et al.   NEUROLOGIA MEDICO-CHIRURGICA

Comparison of the image-derived radioactivity and blood-sample radioactivity for estimating the clinical indicators of the efficacy of boron neutron capture therapy (BNCT): 4-borono-2-18F-fluoro-phenylalanine (FBPA) PET study

(2016) Kayako Isohashi et al.   EJNMMI Research

Biokinetic analysis of tissue boron (10B) concentrations of glioma patients treated with BNCT in Finland

(2015) H. Koivunoro et al.   APPLIED RADIATION AND ISOTOPES

Automated electrophilic radiosynthesis of [18F]FBPA using a modified nucleophilic GE TRACERlab FXFDG

(2015) Severin Mairinger et al.   APPLIED RADIATION AND ISOTOPES

Boronophenylalanine, a boron delivery agent for boron neutron capture therapy, is transported by ATB0,+, LAT1 and LAT2

(2015) Printip Wongthai et al.   CANCER SCIENCE

Effects of l-DOPA pre-loading on the uptake of boronophenylalanine using the F98 glioma and B16 melanoma models

(2014) Weilian Yang et al.   APPLIED RADIATION AND ISOTOPES

Pharmacokinetic Analysis and Uptake of 18F-FBPA-Fr After Ultrasound-Induced Blood-Brain Barrier Disruption for Potential Enhancement of Boron Delivery for Neutron Capture Therapy

(2014) F.-Y. Yang et al.   JOURNAL OF NUCLEAR MEDICINE

Boron neutron capture therapy with bevacizumab may prolong the survival of recurrent malignant glioma patients: four cases

(2014) Shin-Ichi Miyatake et al.   Radiation Oncology

Correlation of 18F-BPA and 18F-FDG uptake in head and neck cancers

(2014) Hitomi Tani et al.   RADIOTHERAPY AND ONCOLOGY

FBPA PET in boron neutron capture therapy for cancer: prediction of 10B concentration in the tumor and normal tissue in a rat xenograft model

(2014) Kohei Hanaoka et al.   EJNMMI Research

Direct comparison of radiation dosimetry of six PET tracers using human whole-body imaging and murine biodistribution studies

(2013) Muneyuki Sakata et al.   ANNALS OF NUCLEAR MEDICINE

Boron neutron capture therapy and 18F-labelled borophenylalanine positron emission tomography: A critical and clinical overview of theliterature

(2013) Laura Evangelista et al.   APPLIED RADIATION AND ISOTOPES

Critical review, with an optimistic outlook, on Boron Neutron Capture Therapy (BNCT)

(2013) Raymond L. Moss   APPLIED RADIATION AND ISOTOPES

Boron neutron capture therapy outcomes for advanced or recurrent head and neck cancer

(2013) M. Suzuki et al.   JOURNAL OF RADIATION RESEARCH

Pulsed-Focused Ultrasound Enhances Boron Drug Accumulation in a Human Head and Neck Cancer Xenograft-Bearing Mouse Model

(2013) Chun-Yi Wu et al.   MOLECULAR IMAGING AND BIOLOGY

Bevacizumab treatment of symptomatic pseudoprogression after boron neutron capture therapy for recurrent malignant gliomas. Report of 2 cases

(2013) Shin-Ichi Miyatake et al.   NEURO-ONCOLOGY

Intra-individual comparison of 18F-FET and 18F-DOPA in PET imaging of recurrent brain tumors

(2013) Clemens Kratochwil et al.   NEURO-ONCOLOGY

Predominant contribution of L-type amino acid transporter to 4-borono-2-18F-fluoro-phenylalanine uptake in human glioblastoma cells

(2013) Mitsuyoshi Yoshimoto et al.   NUCLEAR MEDICINE AND BIOLOGY

Boronated Compounds for Imaging Guided BNCT Applications

(2012) Simonetta Geninatti-Crich et al.   Anti-Cancer Agents in Medicinal Chemistry

Current status of boron neutron capture therapy of high grade gliomas and recurrent head and neck cancer

(2012) Rolf F Barth et al.   Radiation Oncology

A clinical trial protocol for second line treatment of malignant brain tumors with BNCT at University of Tsukuba

(2011) H. Aiyama et al.   APPLIED RADIATION AND ISOTOPES

Experimental verification of beam characteristics for cyclotron-based epithermal neutron source (C-BENS)

(2011) H. Tanaka et al.   APPLIED RADIATION AND ISOTOPES

The status of Tsukuba BNCT trial: BPA-based boron neutron capture therapy combined with X-ray irradiation

(2011) T. Yamamoto et al.   APPLIED RADIATION AND ISOTOPES

BNCT for locally recurrent head and neck cancer: Preliminary clinical experience from a phase I/II trial at Tsing Hua Open-Pool Reactor

(2011) L.W. Wang et al.   APPLIED RADIATION AND ISOTOPES

Boron Neutron Capture Therapy in the Treatment of Locally Recurred Head-and-Neck Cancer: Final Analysis of a Phase I/II Trial

(2011) Leena Kankaanranta et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Fluorine-18-labeled boronophenylalanine positron emission tomography for oral cancers: Qualitative and quantitative analyses of malignant tumors and normal structures in oral and maxillofacial regions

(2011) YASUNORI ARIYOSHI et al.   Oncology Letters

PET pharmacokinetic analysis to estimate boron concentration in tumor and brain as a guide to plan BNCT for malignant cerebral glioma

(2009) Tadashi Nariai et al.   APPLIED RADIATION AND ISOTOPES

Positron emission tomography and [18F]BPA: A perspective application to assess tumour extraction of boron in BNCT

(2009) L. Menichetti et al.   APPLIED RADIATION AND ISOTOPES

Effectiveness of boron neutron capture therapy for recurrent head and neck malignancies

(2009) Itsuro Kato et al.   APPLIED RADIATION AND ISOTOPES

In vivo 19F MR imaging and spectroscopy for the BNCT optimization

(2009) P. Porcari et al.   APPLIED RADIATION AND ISOTOPES

L-Amino Acid Transporter-1 and Boronophenylalanine-Based Boron Neutron Capture Therapy of Human Brain Tumors

(2009) A. Detta et al.   CANCER RESEARCH

Metabolism of borono-phenylalanine–fructose complex (BPA–fr) and borocaptate sodium (BSH) in cancer patients—Results from EORTC trial 11001

(2009) Peter Bendel et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Boron Neutron Capture Therapy for Newly Diagnosed Glioblastoma

(2009) Shinji KAWABATA et al.   JOURNAL OF RADIATION RESEARCH

Pseudoprogression in boron neutron capture therapy for malignant gliomas and meningiomas

(2009) Shin-Ichi Miyatake et al.   NEURO-ONCOLOGY

Characteristics comparison between a cyclotron-based neutron source and KUR-HWNIF for boron neutron capture therapy

(2009) H. Tanaka et al.   NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS

Boron analysis and boron imaging in biological materials for Boron Neutron Capture Therapy (BNCT)

(2008) Andrea Wittig et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

L-DOPA Preloading Increases the Uptake of Borophenylalanine in C6 Glioma Rat Model: A New Strategy to Improve BNCT Efficacy

(2008) Silvia Capuani et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Evaluation of fluoride-labeled boronophenylalanine-PET imaging for the study of radiation effects in patients with glioblastomas

(2008) Minoru Miyashita et al.   JOURNAL OF NEURO-ONCOLOGY

In vivo19F MRI and19F MRS of19F-labelled boronophenylalanine–fructose complex on a C6 rat glioma model to optimize boron neutron capture therapy (BNCT)

(2008) Paola Porcari et al.   PHYSICS IN MEDICINE AND BIOLOGY