Journal
CANCER
Volume 128, Issue 14, Pages 2704-2716Publisher
WILEY
DOI: 10.1002/cncr.34228
Keywords
biomarker; cancer; cancer hallmarks; molecular imaging; positron emission tomography (PET); translational medicine
Categories
Funding
- National Natural Science Foundation of China [81725009, 21788102, 32027802]
- National Key R&D Program of China [2021YFE0108300]
- Fundamental Research Funds for the Central Universities [2021FZZX002-05]
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This article reviews the current status of PET imaging in characterizing cancer hallmarks and discusses the future directions of PET imaging strategies for in vivo cancer phenotyping.
During the past several decades, numerous studies have provided insights into biological characteristics of cancer cells and identified various hallmarks of cancer acquired in the tumorigenic processes. However, it is still challenging to image these distinctive traits of cancer to facilitate the management of patients in clinical settings. The rapidly evolving field of positron emission tomography (PET) imaging has provided opportunities to investigate cancer's biological characteristics in vivo. This article reviews the current status of PET imaging on characterizing hallmarks of cancer and discusses the future directions of PET imaging strategies facilitating in vivo cancer phenotyping.
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