Tumor microenvironment enriches the stemness features: the architectural event of therapy resistance and metastasis
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Title
Tumor microenvironment enriches the stemness features: the architectural event of therapy resistance and metastasis
Authors
Keywords
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Journal
Molecular Cancer
Volume 21, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-12-22
DOI
10.1186/s12943-022-01682-x
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Note: Only part of the references are listed.- Targeting Cancer-Associated Fibroblasts in the Bone Marrow Prevents Resistance to CART-Cell Therapy in Multiple Myeloma
- (2022) Reona Sakemura et al. BLOOD
- Metformin and survival: Is there benefit in a cohort limited to diabetic women with endometrial, breast, or ovarian cancer?
- (2022) Lara S. Lemon et al. GYNECOLOGIC ONCOLOGY
- The YAP/TAZ Signaling Pathway in the Tumor Microenvironment and Carcinogenesis: Current Knowledge and Therapeutic Promises
- (2022) Ángel Ortega et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- MEG3 LncRNA from Exosomes Released from Cancer-Associated Fibroblasts Enhances Cisplatin Chemoresistance in SCLC via a MiR-15a-5p/CCNE1 Axis
- (2022) Yulu Sun et al. YONSEI MEDICAL JOURNAL
- RICH1 inhibits breast cancer stem cell traits through activating kinases cascade of Hippo signaling by competing with Merlin for binding to Amot-p80
- (2022) Qi Tian et al. Cell Death & Disease
- BMI1 nuclear location is critical for RAD51-dependent response to replication stress and drives chemoresistance in breast cancer stem cells
- (2022) Violette Azzoni et al. Cell Death & Disease
- Cancer-associated fibroblast exosomes promote chemoresistance to cisplatin in hepatocellular carcinoma through circZFR targeting signal transducers and activators of transcription (STAT3)/ nuclear factor -kappa B (NF-κB) pathway
- (2022) Yun Zhou et al. Bioengineered
- Dacarbazine-Loaded Targeted Polymeric Nanoparticles for Enhancing Malignant Melanoma Therapy
- (2022) Wei Xiong et al. Frontiers in Bioengineering and Biotechnology
- Pembrolizumab – cancer du sein TN métastatique PD-L1 positif
- (2022) Rebecca Loison et al. BULLETIN DU CANCER
- Targeting Wnt/tenascin C-mediated cross talk between pancreatic cancer cells and stellate cells via activation of the metastasis suppressor NDRG1
- (2022) Bekesho Geleta et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Early response dynamics predict treatment failure in patients with recurrent and/or metastatic head and neck squamous cell carcinoma treated with cetuximab and nivolumab
- (2022) Daniel J. Glazar et al. ORAL ONCOLOGY
- Quality of Life Following Receipt of Adjuvant Chemotherapy With and Without Bevacizumab in Patients With Lymph Node–Positive and High-Risk Lymph Node–Negative Breast Cancer
- (2022) Shoshana M. Rosenberg et al. JAMA Network Open
- Role of myeloid-derived suppressor cells in metastasis
- (2021) Kathryn Cole et al. CANCER AND METASTASIS REVIEWS
- PI3K-driven HER2 expression is a potential therapeutic target in colorectal cancer stem cells
- (2021) Laura Rosa Mangiapane et al. GUT
- AMD3100/Plerixafor overcomes immune inhibition by the CXCL12–KRT19 coating on pancreatic and colorectal cancer cells
- (2021) Douglas T. Fearon et al. BRITISH JOURNAL OF CANCER
- CDK4 and TERT amplification in head and neck mucosal melanoma
- (2021) Jiong Lyu et al. JOURNAL OF ORAL PATHOLOGY & MEDICINE
- Cancer-associated fibroblasts-mediated ATF4 expression promotes malignancy and gemcitabine resistance in pancreatic cancer via the TGF-β1/SMAD2/3 pathway and ABCC1 transactivation
- (2021) Lusheng Wei et al. Cell Death & Disease
- Metastasis-Initiating Cells and Ecosystems
- (2021) Joan Massagué et al. Cancer Discovery
- The gate to metastasis: key players in cancer cell intravasation
- (2021) Magdalena K. Sznurkowska et al. FEBS Journal
- Pancreatic Tumor Microenvironment Factor Promotes Cancer Stemness via SPP1-CD44 Axis
- (2021) Palanisamy Nallasamy et al. GASTROENTEROLOGY
- CAFs shape myeloid‐derived suppressor cells to promote stemness of intrahepatic cholangiocarcinoma via 5‐lipoxygenase
- (2021) Yuli Lin et al. HEPATOLOGY
- Fibroblast pathology in inflammatory joint disease
- (2021) Lucy‐Jayne Marsh et al. IMMUNOLOGICAL REVIEWS
- The Role of the Renin–Angiotensin System in the Cancer Stem Cell Niche
- (2021) Ethan J. Kilmister et al. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
- Adipose stem cell niche reprograms the colorectal cancer stem cell metastatic machinery
- (2021) Simone Di Franco et al. Nature Communications
- A Novel Invadopodia-Specific Marker for Invasive and Pro-Metastatic Cancer Stem Cells
- (2021) Shenq-Shyang Huang et al. Frontiers in Oncology
- Deubiquitinating Enzymes Orchestrate the Cancer Stem Cell-Immunosuppressive Niche Dialogue: New Perspectives and Therapeutic Potential
- (2021) Jun-Nan Guo et al. Frontiers in Cell and Developmental Biology
- Cancer-Associated Fibroblast-Derived Interleukin-8 Promotes Ovarian Cancer Cell Stemness and Malignancy Through the Notch3-Mediated Signaling
- (2021) Zhaodong Ji et al. Frontiers in Cell and Developmental Biology
- Improved osteosarcoma survival with addition of mifamurtide to conventional chemotherapy – Observational prospective single institution analysis
- (2021) Peter Múdry et al. Journal of Bone Oncology
- Role of endothelial cells in tumor microenvironment
- (2021) Dawei Yang et al. Clinical and Translational Medicine
- Metastasis-associated fibroblasts: an emerging target for metastatic cancer
- (2021) Zimu Wang et al. Biomarker Research
- Carcinoma associated fibroblasts small extracellular vesicles with low miR-7641 promotes breast cancer stemness and glycolysis by HIF-1α
- (2021) Yonglei Liu et al. Cell Death Discovery
- Adipose-derived stem/stromal cell secretome modulates breast cancer cell proliferation and differentiation state towards aggressiveness
- (2021) Marcelo Coutinho de Miranda et al. BIOCHIMIE
- CAF promotes chemoresistance through NRP2 in gastric cancer
- (2021) Yanpeng Yang et al. Gastric Cancer
- Reduction in O-glycome induces differentially glycosylated CD44 to promote stemness and metastasis in pancreatic cancer
- (2021) Frank Leon et al. ONCOGENE
- The IL-6R and Bmi-1 axis controls self-renewal and chemoresistance of head and neck cancer stem cells
- (2021) Alexandra E. Herzog et al. Cell Death & Disease
- Myeloid-Derived Suppressor Cells: A Propitious Road to Clinic
- (2021) Amit Grover et al. Cancer Discovery
- Adipose derived mesenchymal stem cell secretome formulation as a biotherapeutic to inhibit growth of drug resistant triple negative breast cancer
- (2021) Ragima Nadesh et al. Scientific Reports
- Marker-free lineage tracing reveals an environment-instructed clonogenic hierarchy in pancreatic cancer
- (2021) Sophie C. Lodestijn et al. Cell Reports
- Avelumab for platinum-ineligible/refractory recurrent and/or metastatic squamous cell carcinoma of the head and neck: phase Ib results from the JAVELIN Solid Tumor trial
- (2021) Joël Guigay et al. Journal for ImmunoTherapy of Cancer
- Cost-Effectiveness of Pembrolizumab Versus Carboplatin and Paclitaxel in Patients With Unresectable or Metastatic Melanoma After First-Line Treatment in China
- (2021) Wen-xi Tang et al. Value in Health Regional Issues
- Adipose‐derived stem cells and cancer cells fuse to generate cancer stem cell‐like cells with increased tumorigenicity
- (2020) Yuk Wah Chan et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Angiocrine endothelium: from physiology to cancer
- (2020) Jennifer Pasquier et al. Journal of Translational Medicine
- MAOA-mediated reprogramming of stromal fibroblasts promotes prostate tumorigenesis and cancer stemness
- (2020) Jingjing Li et al. ONCOGENE
- Wnt-mediated endothelial transformation into mesenchymal stem cell–like cells induces chemoresistance in glioblastoma
- (2020) Menggui Huang et al. Science Translational Medicine
- Proinflammatory cytokine TNFα promotes HPV-associated oral carcinogenesis by increasing cancer stemness
- (2020) Hannah S. Hong et al. International Journal of Oral Science
- TNF-α increases breast cancer stem-like cells through up-regulating TAZ expression via the non-canonical NF-κB pathway
- (2020) Wenjing Liu et al. Scientific Reports
- Tumor-Associated Macrophages: Recent Insights and Therapies
- (2020) Jiawei Zhou et al. Frontiers in Oncology
- Tumor microenvironment complexity and therapeutic implications at a glance
- (2020) Roghayyeh Baghban et al. Cell Communication and Signaling
- Cancer Stem Cell Chemotherapeutics Assay for Prospective Treatment of Recurrent Glioblastoma and Progressive Anaplastic Glioma: A Single-Institution Case Series
- (2020) Tulika Ranjan et al. Translational Oncology
- CCL5 derived from tumor-associated macrophages promotes prostate cancer stem cells and metastasis via activating β-catenin/STAT3 signaling
- (2020) Renlun Huang et al. Cell Death & Disease
- ALKS 4230: a novel engineered IL-2 fusion protein with an improved cellular selectivity profile for cancer immunotherapy
- (2020) Jared E Lopes et al. Journal for ImmunoTherapy of Cancer
- Anti-EGFR Therapy Induces EGF Secretion by Cancer-Associated Fibroblasts to Confer Colorectal Cancer Chemoresistance
- (2020) Colleen M. Garvey et al. Cancers
- Isoprenylcysteine carboxylmethyltransferase is required for the impact of mutant KRAS on TAZ protein level and cancer cell self-renewal
- (2020) Tin Fan Chai et al. ONCOGENE
- Cell stemness is maintained upon concurrent expression of RB and the mitochondrial ribosomal protein S18-2
- (2020) Muhammad Mushtaq et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Irradiated mesenchymal stem cells support stemness maintenance of hepatocellular carcinoma stem cells through Wnt/β-catenin signaling pathway
- (2020) Jing Hou et al. Cell and Bioscience
- Cancer-associated fibroblasts enhance the chemoresistance of CD73+ hepatocellular carcinoma cancer cells via HGF-Met-ERK1/2 pathway
- (2020) Hao Peng et al. Annals of Translational Medicine
- Stress-induced upregulation of TNFSF4 in cancer-associated fibroblast facilitates chemoresistance of lung adenocarcinoma through inhibiting apoptosis of tumor cells
- (2020) Yan Li et al. CANCER LETTERS
- Transcription factor YY1 enhances the stemness of lung cancer cells by stabilizing hypoxia factor HIF ‐1α under a hypoxic microenvironment
- (2020) Xianping Huang et al. ENVIRONMENTAL TOXICOLOGY
- Exosomal lncRNA UCA1 from cancer‐associated fibroblasts enhances chemoresistance in vulvar squamous cell carcinoma cells
- (2020) Qianqian Gao et al. JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
- IRF2 maintains the stemness of colonic stem cells by limiting physiological stress from interferon
- (2020) Kana Minamide et al. Scientific Reports
- Adipose-derived mesenchymal stem cells promote the malignant phenotype of cervical cancer
- (2020) Rosario Castro-Oropeza et al. Scientific Reports
- Targeting interleukin-17 receptor B enhances gemcitabine sensitivity through downregulation of mucins in pancreatic cancer
- (2020) Lung-Hung Tsai et al. Scientific Reports
- BTF3 promotes stemness and inhibits TypeⅠInterferon signaling pathway in triple-negative breast cancer
- (2020) Hexiang Wang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Partial acquisition of stemness properties in tumorspheres obtained from interleukin-8-treated MCF-7 cells
- (2020) Natalia Ospina-Muñoz et al. TUMOR BIOLOGY
- IL-6 promotes nuclear translocation of HIF-1α to aggravate chemoresistance of ovarian cancer cells
- (2020) Shiwen Xu et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Adipogenesis and metabolic health
- (2019) Alexandra L. Ghaben et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- In search of definitions: Cancer-associated fibroblasts and their markers
- (2019) Martin Nurmik et al. INTERNATIONAL JOURNAL OF CANCER
- IL-10 derived from M2 macrophage promotes cancer stemness via JAK1/STAT1/NF-κB/Notch1 pathway in non-small cell lung cancer
- (2019) Li Yang et al. INTERNATIONAL JOURNAL OF CANCER
- Low-dose IFN-γ induces tumor cell stemness in the tumor microenvironment of non-small cell lung cancer
- (2019) Mengjia Song et al. CANCER RESEARCH
- Myeloid-derived suppressor cells endow stem-like qualities to multiple myeloma cells by inducing piRNA-823 expression and DNMT3B activation
- (2019) Lisha Ai et al. Molecular Cancer
- Targeting Tumor-Associated Macrophages in Cancer
- (2019) Paulina Pathria et al. TRENDS IN IMMUNOLOGY
- Macrophages and Metabolism in the Tumor Microenvironment
- (2019) Ilio Vitale et al. Cell Metabolism
- Mesenchymal stromal cells confer chemoresistance to myeloid leukemia blasts through Side Population functionality and ABC transporter activation
- (2019) Laetitia Boutin et al. HAEMATOLOGICA
- Tumor-associated macrophages in tumor metastasis: biological roles and clinical therapeutic applications
- (2019) Yuxin Lin et al. Journal of Hematology & Oncology
- Insights into new mechanisms and models of cancer stem cell multidrug resistance
- (2019) Y. Garcia-Mayea et al. SEMINARS IN CANCER BIOLOGY
- Concise Review: Adipose Stem Cells and Cancer
- (2019) Rachel A. Sabol et al. STEM CELLS
- Endothelial cells promote 3D invasion of GBM by IL-8-dependent induction of cancer stem cell properties
- (2019) Michael G. McCoy et al. Scientific Reports
- Granulocytic Myeloid‐Derived Suppressor Cells Promote the Stemness of Colorectal Cancer Cells through Exosomal S100A9
- (2019) Yungang Wang et al. Advanced Science
- The mechanism of the premetastatic niche facilitating colorectal cancer liver metastasis generated from myeloid-derived suppressor cells induced by the S1PR1–STAT3 signaling pathway
- (2019) Qi Lin et al. Cell Death & Disease
- RBCK1 contributes to chemoresistance and stemness in colorectal cancer (CRC)
- (2019) Min-Li Liu et al. BIOMEDICINE & PHARMACOTHERAPY
- Hyaluronan-CD44 axis orchestrates cancer stem cell functions
- (2019) Spyros S. Skandalis et al. CELLULAR SIGNALLING
- CCL8 secreted by tumor-associated macrophages promotes invasion and stemness of glioblastoma cells via ERK1/2 signaling
- (2019) Xiang Zhang et al. LABORATORY INVESTIGATION
- Targeting signalling pathways and the immune microenvironment of cancer stem cells — a clinical update
- (2019) Joseph A. Clara et al. Nature Reviews Clinical Oncology
- Co-culture of ovarian cancer stem-like cells with macrophages induced SKOV3 cells stemness via IL-8/STAT3 signaling
- (2018) Yingxia Ning et al. BIOMEDICINE & PHARMACOTHERAPY
- CD10 + GPR77 + Cancer-Associated Fibroblasts Promote Cancer Formation and Chemoresistance by Sustaining Cancer Stemness
- (2018) Shicheng Su et al. CELL
- Hypoxic tumor microenvironment activates GLI2 via HIF-1α and TGF-β2 to promote chemoresistance in colorectal cancer
- (2018) Yen-An Tang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Effects of Cetuximab and Erlotinib on the behaviour of cancer stem cells in head and neck squamous cell carcinoma
- (2018) Maria Fernanda Setúbal Destro Rodrigues et al. Oncotarget
- Carcinoma-associated fibroblasts promote the stemness and chemoresistance of colorectal cancer by transferring exosomal lncRNA H19
- (2018) Jing Ren et al. Theranostics
- Glycosylation of Cancer Stem Cells: Function in Stemness, Tumorigenesis, and Metastasis
- (2018) Srikanth Barkeer et al. NEOPLASIA
- Interleukin 7-expressing fibroblasts promote breast cancer growth through sustenance of tumor cell stemness
- (2018) Maximilian Boesch et al. OncoImmunology
- Cancer Stem Cell Vaccination With PD-L1 and CTLA-4 Blockades Enhances the Eradication of Melanoma Stem Cells in a Mouse Tumor Model
- (2018) Fang Zheng et al. JOURNAL OF IMMUNOTHERAPY
- Endothelial Cells Promote Colorectal Cancer Cell Survival by Activating the HER3-AKT Pathway in a Paracrine Fashion
- (2018) Rui Wang et al. MOLECULAR CANCER RESEARCH
- Stem cell functionality is microenvironmentally defined during tumour expansion and therapy response in colon cancer
- (2018) Kristiaan J. Lenos et al. NATURE CELL BIOLOGY
- First-Line Atezolizumab plus Chemotherapy in Extensive-Stage Small-Cell Lung Cancer
- (2018) Leora Horn et al. NEW ENGLAND JOURNAL OF MEDICINE
- Adipose-derived stem cells enhance human breast cancer growth and cancer stem cell-like properties through adipsin
- (2018) Hideaki Goto et al. ONCOGENE
- Unraveling the journey of cancer stem cells from origin to metastasis
- (2018) Rama Krishna Nimmakayala et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Cancer-associated fibroblasts promote the stemness of CD24+ liver cells via paracrine signaling
- (2018) Yawen Li et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Hypoxia‐inducible factor‐2α directly promotes BCRP expression and mediates the resistance of ovarian cancer stem cells to adriamycin
- (2018) Miao He et al. Molecular Oncology
- Turning foes to friends: targeting cancer-associated fibroblasts
- (2018) Xueman Chen et al. NATURE REVIEWS DRUG DISCOVERY
- Tumor cell-secreted PLD increases tumor stemness by senescence-mediated communication with microenvironment
- (2018) Sandra Muñoz-Galván et al. ONCOGENE
- A subtype of cancer-associated fibroblasts with lower expression of alpha-smooth muscle actin suppresses stemness through BMP4 in oral carcinoma
- (2018) Ankit Kumar Patel et al. Oncogenesis
- SENP1 promotes hypoxia-induced cancer stemness by HIF-1α deSUMOylation and SENP1/HIF-1α positive feedback loop
- (2017) Chun-Ping Cui et al. GUT
- IL6-mediated inflammatory loop reprograms normal to epithelial-mesenchymal transition+ metastatic cancer stem cells in preneoplastic liver of transforming growth factor beta-deficient β2-spectrin+/− mice
- (2017) Abhisek Mitra et al. HEPATOLOGY
- Tricking the balance: NK cells in anti-cancer immunity
- (2017) Jens Pahl et al. IMMUNOBIOLOGY
- PD-1 blockade enhances the antitumor efficacy of GM-CSF surface-modified bladder cancer stem cells vaccine
- (2017) Xiaojun Shi et al. INTERNATIONAL JOURNAL OF CANCER
- ABC Transporters in Cancer Stem Cells: Beyond Chemoresistance
- (2017) Romana-Rea Begicevic et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- High-mobility group box 1 released by autophagic cancer-associated fibroblasts maintains the stemness of luminal breast cancer cells
- (2017) Xi-Long Zhao et al. JOURNAL OF PATHOLOGY
- Endothelial cells activate the cancer stem cell-associated NANOGP8 pathway in colorectal cancer cells in a paracrine fashion
- (2017) Rui Wang et al. Molecular Oncology
- Protein Nanocage Mediated Fibroblast-Activation Protein Targeted Photoimmunotherapy To Enhance Cytotoxic T Cell Infiltration and Tumor Control
- (2017) Zipeng Zhen et al. NANO LETTERS
- Cancer stem cells revisited
- (2017) Eduard Batlle et al. NATURE MEDICINE
- Sox2 Communicates with Tregs Through CCL1 to Promote the Stemness Property of Breast Cancer Cells
- (2017) Yingxi Xu et al. STEM CELLS
- Peri-foci adipose-derived stem cells promote chemoresistance in breast cancer
- (2017) Wei-Lan Yeh et al. Stem Cell Research & Therapy
- Epithelial-mesenchymal transition: potential regulator of ABC transporters in tumor progression
- (2017) Zong-Sheng Jiang et al. Journal of Cancer
- Stemness in Cancer: Stem Cells, Cancer Stem Cells, and Their Microenvironment
- (2017) Pedro M. Aponte et al. Stem Cells International
- A cancer stem cell model as the point of origin of cancer-associated fibroblasts in tumor microenvironment
- (2017) Neha Nair et al. Scientific Reports
- Collaboration of 3D context and extracellular matrix in the development of glioma stemness in a 3D model
- (2016) Nina K.L. Ma et al. BIOMATERIALS
- CD133+ liver cancer stem cells resist interferon-gamma-induced autophagy
- (2016) Jian Li et al. BMC CANCER
- Extracellular Vesicles in Cancer: Cell-to-Cell Mediators of Metastasis
- (2016) Annette Becker et al. CANCER CELL
- Role of the tumor microenvironment in regulating apoptosis and cancer progression
- (2016) Katherine Yaacoub et al. CANCER LETTERS
- Non-CSCs nourish CSCs through interleukin-17E-mediated activation of NF-κB and JAK/STAT3 signaling in human hepatocellular carcinoma
- (2016) Yongli Luo et al. CANCER LETTERS
- Cisplatin treatment increases stemness through upregulation of hypoxia-inducible factors by interleukin-6 in non-small cell lung cancer
- (2016) Fuquan Zhang et al. CANCER SCIENCE
- Tackling multidrug resistance mediated by efflux transporters in tumor-initiating cells
- (2016) Kyle McIntosh et al. Expert Opinion on Drug Metabolism & Toxicology
- Comparison of Multidetector CT and Gadobutrol-Enhanced MR Imaging for Evaluation of Small, Solid Pancreatic Lesions
- (2016) Tae Won Choi et al. KOREAN JOURNAL OF RADIOLOGY
- MUC13 protects colorectal cancer cells from death by activating the NF-κB pathway and is a potential therapeutic target
- (2016) Y H Sheng et al. ONCOGENE
- The promotion of the transformation of quiescent gastric cancer stem cells by IL-17 and the underlying mechanisms
- (2016) Y-X Jiang et al. ONCOGENE
- Cancer stem cells and chemoresistance: The smartest survives the raid
- (2016) Jihe Zhao PHARMACOLOGY & THERAPEUTICS
- Tumor-Activated Mesenchymal Stromal Cells Promote Osteosarcoma Stemness and Migratory Potential via IL-6 Secretion
- (2016) Margherita Cortini et al. PLoS One
- Cancer Stem Cell-Secreted Macrophage Migration Inhibitory Factor Stimulates Myeloid Derived Suppressor Cell Function and Facilitates Glioblastoma Immune Evasion
- (2016) Balint Otvos et al. STEM CELLS
- Preferential expression of functional IL-17R in glioma stem cells: potential role in self-renewal
- (2016) Prahlad Parajuli et al. Oncotarget
- JNK pathway inhibition selectively primes pancreatic cancer stem cells to TRAIL-induced apoptosis without affecting the physiology of normal tissue resident stem cells
- (2016) Alejandro Recio-Boiles et al. Oncotarget
- Modulation of macrophage polarization and lung cancer cell stemness by MUC1 and development of a related small-molecule inhibitor pterostilbene
- (2016) Wen-Chien Huang et al. Oncotarget
- Cancer-Associated Fibroblasts Regulate Tumor-Initiating Cell Plasticity in Hepatocellular Carcinoma through c-Met/FRA1/HEY1 Signaling
- (2016) Eunice Yuen Ting Lau et al. Cell Reports
- Interleukin-6 from Ovarian Mesenchymal Stem Cells Promotes Proliferation, Sphere and Colony Formation and Tumorigenesis of an Ovarian Cancer Cell Line SKOV3
- (2016) Dah-Ching Ding et al. Journal of Cancer
- Tumour endothelial cells in high metastatic tumours promote metastasis via epigenetic dysregulation of biglycan
- (2016) Nako Maishi et al. Scientific Reports
- Transmembrane TNF- preferentially expressed by leukemia stem cells and blasts is a potent target for antibody therapy
- (2015) X. Zhou et al. BLOOD
- Atonal homolog 1 protein stabilized by tumor necrosis factor α induces high malignant potential in colon cancer cell line
- (2015) Keita Fukushima et al. CANCER SCIENCE
- mPGES-1 in prostate cancer controls stemness and amplifies epidermal growth factor receptor-driven oncogenicity
- (2015) Federica Finetti et al. ENDOCRINE-RELATED CANCER
- CD90+stromal cells are the major source of IL-6, which supports cancer stem-like cells and inflammation in colorectal cancer
- (2015) Phuong T. Huynh et al. INTERNATIONAL JOURNAL OF CANCER
- Myeloid-derived suppressor cells in the tumor microenvironment: expect the unexpected
- (2015) Douglas Marvel et al. JOURNAL OF CLINICAL INVESTIGATION
- Endothelial cells induce cancer stem cell features in differentiated glioblastoma cells via bFGF
- (2015) Evelyn Fessler et al. Molecular Cancer
- Cancer stem cells and tumor-associated macrophages: a roadmap for multitargeting strategies
- (2015) C Raggi et al. ONCOGENE
- IL-6 signaling promotes DNA repair and prevents apoptosis in CD133+ stem-like cells of lung cancer after radiation
- (2015) Yuhchyau Chen et al. Radiation Oncology
- Mesenchymal Stem Cells Isolated From Human Gliomas Increase Proliferation and Maintain Stemness of Glioma Stem Cells Through the IL-6/gp130/STAT3 Pathway
- (2015) Anwar Hossain et al. STEM CELLS
- IL-6 promotes growth and epithelial-mesenchymal transition of CD133+ cells of non-small cell lung cancer
- (2015) Soo Ok Lee et al. Oncotarget
- ILs-3, 6 and 11 increase, but ILs-10 and 24 decrease stemness of human prostate cancer cells in vitro
- (2015) Dan-Dan Yu et al. Oncotarget
- Systemic use of tumor necrosis factor alpha as an anticancer agent
- (2015) Nicholas J. Roberts et al. Oncotarget
- Tumor-induced STAT3 activation in monocytic myeloid-derived suppressor cells enhances stemness and mesenchymal properties in human pancreatic cancer
- (2014) Roheena Z. Panni et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Tumor-associated macrophages promote cancer stem cell-like properties via transforming growth factor-beta1-induced epithelial–mesenchymal transition in hepatocellular carcinoma
- (2014) Qing-Min Fan et al. CANCER LETTERS
- Cancer Stem-like Cells Derived from Chemoresistant Tumors Have a Unique Capacity to Prime Tumorigenic Myeloid Cells
- (2014) T. Yamashina et al. CANCER RESEARCH
- JNK1 stress signaling is hyper-activated in high breast density and the tumor stroma: Connecting fibrosis, inflammation, and stemness for cancer prevention
- (2014) Michael P Lisanti et al. CELL CYCLE
- Human colonic fibroblasts regulate stemness and chemotherapy resistance of colon cancer stem cells
- (2014) S. Colak et al. CELL CYCLE
- Evolution of the Cancer Stem Cell Model
- (2014) Antonija Kreso et al. Cell Stem Cell
- Influence of interferon-α on the expression of the cancer stem cell markers in pancreatic carcinoma cells
- (2014) Yifan Zhu et al. EXPERIMENTAL CELL RESEARCH
- IL-22+CD4+ T Cells Promote Colorectal Cancer Stemness via STAT3 Transcription Factor Activation and Induction of the Methyltransferase DOT1L
- (2014) Ilona Kryczek et al. IMMUNITY
- ABC Transporters in Multi-Drug Resistance and ADME-Tox of Small Molecule Tyrosine Kinase Inhibitors
- (2014) Jiexin Deng et al. PHARMACEUTICAL RESEARCH
- Endothelial Cells Provide a Notch-Dependent Pro-Tumoral Niche for Enhancing Breast Cancer Survival, Stemness and Pro-Metastatic Properties
- (2014) Pegah Ghiabi et al. PLoS One
- CD133+ cells contribute to radioresistance via altered regulation of DNA repair genes in human lung cancer cells
- (2014) Amar Desai et al. RADIOTHERAPY AND ONCOLOGY
- The two faces of IL-6 in the tumor microenvironment
- (2014) Daniel T. Fisher et al. SEMINARS IN IMMUNOLOGY
- Cancer-associated fibroblasts regulate the plasticity of lung cancer stemness via paracrine signalling
- (2014) Wan-Jiun Chen et al. Nature Communications
- Regulated Splicing of the α6 Integrin Cytoplasmic Domain Determines the Fate of Breast Cancer Stem Cells
- (2014) Hira Lal Goel et al. Cell Reports
- Endothelial Cells Promote the Colorectal Cancer Stem Cell Phenotype through a Soluble Form of Jagged-1
- (2013) Jia Lu et al. CANCER CELL
- Myeloid-Derived Suppressor Cells Enhance Stemness of Cancer Cells by Inducing MicroRNA101 and Suppressing the Corepressor CtBP2
- (2013) Tracy X. Cui et al. IMMUNITY
- Cancer-associated fibroblasts might sustain the stemness of scirrhous gastric cancer cells via transforming growth factor-β signaling
- (2013) Tsuyoshi Hasegawa et al. INTERNATIONAL JOURNAL OF CANCER
- Hypoxia-inducing factors as master regulators of stemness properties and altered metabolism of cancer- and metastasis-initiating cells
- (2013) Murielle Mimeault et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Cytotoxic T cells induce proliferation of chronic myeloid leukemia stem cells by secreting interferon-γ
- (2013) Christian Schürch et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Chemotherapy activates cancer-associated fibroblasts to maintain colorectal cancer-initiating cells by IL-17A
- (2013) Fiorenza Lotti et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Microenvironmental regulation of tumor progression and metastasis
- (2013) Daniela F Quail et al. NATURE MEDICINE
- Interleukin-17 produced by tumor microenvironment promotes self-renewal of CD133+ cancer stem-like cells in ovarian cancer
- (2013) T Xiang et al. ONCOGENE
- Tumor and its microenvironment: A synergistic interplay
- (2013) Veronica Catalano et al. SEMINARS IN CANCER BIOLOGY
- CD44 Expressed on Cancer-Associated Fibroblasts Is a Functional Molecule Supporting the Stemness and Drug Resistance of Malignant Cancer Cells in the Tumor Microenvironment
- (2013) Yumi Kinugasa et al. STEM CELLS
- TNFα enhances cancer stem cell-like phenotype via Notch-Hes1 activation in oral squamous cell carcinoma cells
- (2012) Sung Hee Lee et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Interferon regulatory factor 7 regulates glioma stem cells via interleukin-6 and Notch signalling
- (2012) X. Jin et al. BRAIN
- Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment
- (2012) Douglas Hanahan et al. CANCER CELL
- Reciprocal Metabolic Reprogramming through Lactate Shuttle Coordinately Influences Tumor-Stroma Interplay
- (2012) T. Fiaschi et al. CANCER RESEARCH
- Reciprocal Interactions between Tumor-Associated Macrophages and CD44-Positive Cancer Cells via Osteopontin/CD44 Promote Tumorigenicity in Colorectal Cancer
- (2012) G. Rao et al. CLINICAL CANCER RESEARCH
- Tumor-Associated Microglia/Macrophages Enhance the Invasion of Glioma Stem-like Cells via TGF- 1 Signaling Pathway
- (2012) X.-z. Ye et al. JOURNAL OF IMMUNOLOGY
- Tumor necrosis factor-α (TNF-α) stimulates the epithelial–mesenchymal transition regulator Snail in cholangiocarcinoma
- (2012) Anchalee Techasen et al. MEDICAL ONCOLOGY
- Clonal evolution in cancer
- (2012) Mel Greaves et al. NATURE
- Tumor Associated Macrophage × Cancer Cell Hybrids May Acquire Cancer Stem Cell Properties in Breast Cancer
- (2012) Jingxian Ding et al. PLoS One
- Variable Clonal Repopulation Dynamics Influence Chemotherapy Response in Colorectal Cancer
- (2012) A. Kreso et al. SCIENCE
- Cancer Associated Fibroblasts Exploit Reactive Oxygen Species Through a Proinflammatory Signature Leading to Epithelial Mesenchymal Transition and Stemness
- (2011) Elisa Giannoni et al. ANTIOXIDANTS & REDOX SIGNALING
- Tumor Metastasis: Molecular Insights and Evolving Paradigms
- (2011) Scott Valastyan et al. CELL
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Ketones and lactate increase cancer cell “stemness,” driving recurrence, metastasis and poor clinical outcome in breast cancer
- (2011) Ubaldo E. Martinez-Outschoorn et al. CELL CYCLE
- Induction of metastatic cancer stem cells from the NK/LAK-resistant floating, but not adherent, subset of the UP-LN1 carcinoma cell line by IFN-γ
- (2011) Hung-Chang Chen et al. LABORATORY INVESTIGATION
- Interactions between cancer stem cells and their niche govern metastatic colonization
- (2011) Ilaria Malanchi et al. NATURE
- Tumor-associated macrophages regulate tumorigenicity and anticancer drug responses of cancer stem/initiating cells
- (2011) M. Jinushi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Reciprocal Activation of Prostate Cancer Cells and Cancer-Associated Fibroblasts Stimulates Epithelial-Mesenchymal Transition and Cancer Stemness
- (2010) E. Giannoni et al. CANCER RESEARCH
- Retinoid signaling regulates breast cancer stem cell differentiation
- (2010) Christophe Ginestier et al. CELL CYCLE
- Differentiation Therapy Exerts Antitumor Effects on Stem-like Glioma Cells
- (2010) B. Campos et al. CLINICAL CANCER RESEARCH
- Immunoregulatory properties of CD44+ cancer stem-like cells in squamous cell carcinoma of the head and neck
- (2010) Kazuaki Chikamatsu et al. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
- Loss of transforming growth factor β adaptor protein β-2 spectrin leads to delayed liver regeneration in mice
- (2010) Arun Thenappan et al. HEPATOLOGY
- TNFalpha up-regulates SLUG via the NF-kappaB/HIF1alpha axis, which imparts breast cancer cells with a stem cell-like phenotype
- (2010) Gianluca Storci et al. JOURNAL OF CELLULAR PHYSIOLOGY
- The therapeutic promise of the cancer stem cell concept
- (2010) Natasha Y. Frank et al. JOURNAL OF CLINICAL INVESTIGATION
- Foxp3+ IL-17+ T cells promote development of cancer-initiating cells in colorectal cancer
- (2010) Shaobo Yang et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Monoclonal antibody therapy directed against human acute myeloid leukemia stem cells
- (2010) R Majeti ONCOGENE
- Hyaluronan-CD44 Interaction Activates Stem Cell Marker Nanog, Stat-3-mediated MDR1 Gene Expression, and Ankyrin-regulated Multidrug Efflux in Breast and Ovarian Tumor Cells
- (2008) Lilly Y. W. Bourguignon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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