Sox2 Communicates with Tregs Through CCL1 to Promote the Stemness Property of Breast Cancer Cells

Expression of Sox2 in breast cancer cells promotes the recruitment of M2 macrophages to tumor microenvironment

(2015) Wenjun Mou et al.   CANCER LETTERS

Functional and molecular characterisation of EO771.LMB tumours, a new C57BL/6-mouse-derived model of spontaneously metastatic mammary cancer

(2015) C. N. Johnstone et al.   Disease Models & Mechanisms

Chemotherapy induces the cancer-associated fibroblast phenotype, activating paracrine Hedgehog-GLI signalling in breast cancer cells

(2015) Maria Peiris-Pagès et al.   Oncotarget

STIM1 accelerates cell senescence in a remodeled microenvironment but enhances the epithelial-to-mesenchymal transition in prostate cancer

(2015) Yingxi Xu et al.   Scientific Reports

Disruption of CCR5-Dependent Homing of Regulatory T Cells Inhibits Tumor Growth in a Murine Model of Pancreatic Cancer

(2014) M. C. B. Tan et al.   JOURNAL OF IMMUNOLOGY

TAZ is required for metastatic activity and chemoresistance of breast cancer stem cells

(2014) M Bartucci et al.   ONCOGENE

GRP78 secreted by tumor cells stimulates differentiation of bone marrow mesenchymal stem cells to cancer-associated fibroblasts

(2013) Yanan Peng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

FOXP3-positive regulatory T lymphocytes and epithelial FOXP3 expression in synchronous normal, ductal carcinoma in situ, and invasive cancer of the breast

(2013) Aseem Lal et al.   BREAST CANCER RESEARCH AND TREATMENT

Endothelial Cells Promote the Colorectal Cancer Stem Cell Phenotype through a Soluble Form of Jagged-1

(2013) Jia Lu et al.   CANCER CELL

Grp78 as a therapeutic target for refractory head–neck cancer with CD24−CD44+ stemness phenotype

(2013) C-C Chiu et al.   CANCER GENE THERAPY

SOX2 promotes tumor metastasis by stimulating epithelial-to-mesenchymal transition via regulation of WNT/β-catenin signal network

(2013) Xuefei Li et al.   CANCER LETTERS

Specific Recruitment of    Regulatory T Cells in Human Breast Cancer

(2013) J. Ye et al.   CANCER RESEARCH

SOX2 regulates apoptosis through MAP4K4-Survivin signaling pathway in human lung cancer cells

(2013) Si Chen et al.   CARCINOGENESIS

CCL5 as a potential immunotherapeutic target in triple-negative breast cancer

(2013) Dandan Lv et al.   Cellular & Molecular Immunology

Possible involvement of CCL1-CCR8 interaction in lymphocytic recruitment in IgG4-related sclerosing cholangitis

(2013) Yoh Zen et al.   JOURNAL OF HEPATOLOGY

Tumor-Derived    Regulatory T Cells Suppress Innate and Adaptive Immunity through the Induction of Immunosenescence

(2013) J. Ye et al.   JOURNAL OF IMMUNOLOGY

Inhibition of Lung Metastasis by Chemokine CCL17-mediated In Vivo Silencing of Genes in CCR4+ Tregs

(2013) Arya Biragyn et al.   JOURNAL OF IMMUNOTHERAPY

Pluripotent Stem Cell Protein Sox2 Confers Sensitivity to LSD1 Inhibition in Cancer Cells

(2013) Xiaoming Zhang et al.   Cell Reports

Targeting Tumor-Infiltrating Macrophages Decreases Tumor-Initiating Cells, Relieves Immunosuppression, and Improves Chemotherapeutic Responses

(2012) J. B. Mitchem et al.   CANCER RESEARCH

Cancer Stem Cells: Current Status and Evolving Complexities

(2012) Jane E. Visvader et al.   Cell Stem Cell

Interaction between regulatory T cells and cancer stem cells

(2012) Xiaozhou Yu et al.   INTERNATIONAL JOURNAL OF CANCER

Met signaling regulates growth, repopulating potential and basal cell-fate commitment of mammary luminal progenitors: implications for basal-like breast cancer

(2012) S Gastaldi et al.   ONCOGENE

SOX2 Gene Regulates the Transcriptional Network of Oncogenes and Affects Tumorigenesis of Human Lung Cancer Cells

(2012) Si Chen et al.   PLoS One

CD25 Blockade Depletes and Selectively Reprograms Regulatory T Cells in Concert with Immunotherapy in Cancer Patients

(2012) A. J. Rech et al.   Science Translational Medicine

Tumor-Associated Macrophages Regulate Murine Breast Cancer Stem Cells Through a Novel Paracrine EGFR/Stat3/Sox-2 Signaling Pathway

(2012) Jian Yang et al.   STEM CELLS

Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells

(2011) Piyush B. Gupta et al.   CELL

Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and Treg cells

(2011) Andrea Facciabene et al.   NATURE

Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state

(2011) C. L. Chaffer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SOX2 promotes tumorigenesis and increases the anti-apoptotic property of human prostate cancer cell

(2011) X. Jia et al.   Journal of Molecular Cell Biology

The Canonical NF- B Pathway Governs Mammary Tumorigenesis in Transgenic Mice and Tumor Stem Cell Expansion

(2010) M. Liu et al.   CANCER RESEARCH

Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells

(2010) Lucia Ricci-Vitiani et al.   NATURE

Glioblastoma stem-like cells give rise to tumour endothelium

(2010) Rong Wang et al.   NATURE

Glioma cancer stem cells induce immunosuppressive macrophages/microglia

(2010) Adam Wu et al.   NEURO-ONCOLOGY

Breast Cancer Lung Metastasis Requires Expression of Chemokine Receptor CCR4 and Regulatory T Cells

(2009) P. B. Olkhanud et al.   CANCER RESEARCH

Regulatory T Cells Recruited through CCL22/CCR4 Are Selectively Activated in Lymphoid Infiltrates Surrounding Primary Breast Tumors and Lead to an Adverse Clinical Outcome

(2009) M. Gobert et al.   CANCER RESEARCH