Assessing the in vitro toxicity of airborne (nano)particles to the human respiratory system: from basic to advanced models

Advanced Respiratory Models for Hazard Assessment of Nanomaterials—Performance of Mono-, Co- and Tricultures

(2022) Laura Maria Azzurra Camassa et al.   Nanomaterials

Lung Organoids for Hazard Assessment of Nanomaterials

(2022) Miriam T. Kastlmeier et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nanomaterial-induced toxicity in pathophysiological models representative of individuals with pre-existing medical conditions

(2022) Sreejesh Sreedharan et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

Advanced Multi-Dimensional Cellular Models as Emerging Reality to Reproduce In Vitro the Human Body Complexity

(2021) Giada Bassi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Development of Human Lung Induction Models for Air Pollutants’ Toxicity Assessment

(2021) Shuyu Liu et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Engineering organoids

(2021) Moritz Hofer et al.   Nature Reviews Materials

Toxicity assessment of industrial engineered and airborne process-generated nanoparticles in a 3D human airway epithelial in vitro model

(2021) Maria João Bessa et al.   Nanotoxicology

Nanomaterials and hepatic disease: toxicokinetics, disease types, intrinsic mechanisms, liver susceptibility, and influencing factors

(2021) Ting Sun et al.   JOURNAL OF NANOBIOTECHNOLOGY

Air pollution and children’s health—a review of adverse effects associated with prenatal exposure from fine to ultrafine particulate matter

(2021) Natalie M. Johnson et al.   Environmental Health and Preventive Medicine

Organoid Technology: A Reliable Developmental Biology Tool for Organ-Specific Nanotoxicity Evaluation

(2021) Minakshi Prasad et al.   Frontiers in Cell and Developmental Biology

Adverse cardiovascular responses of engineered nanomaterials: Current understanding of molecular mechanisms and future challenges

(2021) Nasser B. Alsaleh   Nanomedicine-Nanotechnology Biology and Medicine

In vitro impact preliminary assessment of airborne particulate from metalworking and woodworking industries

(2021) Ilona Pavlovska et al.   Scientific Reports

In Vitro Toxicity of Industrially Relevant Engineered Nanoparticles in Human Alveolar Epithelial Cells: Air–Liquid Interface versus Submerged Cultures

(2021) Maria João Bessa et al.   Nanomaterials

Use of in vitro 3D tissue models in genotoxicity testing: Strategic fit, validation status and way forward. Report of the working group from the 7th International Workshop on Genotoxicity Testing (IWGT)

(2020) Stefan Pfuhler et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Prediction of Aerosol Deposition in the Human Respiratory Tract via Computational Models: A Review with Recent Updates

(2020) Vu Khac Hoang Bui et al.   Atmosphere

Use of EpiAlveolar Lung Model to Predict Fibrotic Potential of Multiwalled Carbon Nanotubes

(2020) Hana Barosova et al.   ACS Nano

Evaluation and live monitoring of pH-responsive HSA-ZnO nanoparticles using a lung-on-a-chip model

(2020) Nileshkumar Meghani et al.   ARCHIVES OF PHARMACAL RESEARCH

Comparison of silver nanoparticle-induced inflammatory responses between healthy and metabolic syndrome mouse models

(2020) Lisa Kobos et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

A review of hepatic nanotoxicology – summation of recent findings and considerations for the next generation of study designs

(2020) Ali Kermanizadeh et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

A pre‐ investigational new drug study of lung spheroid cell therapy for treating pulmonary fibrosis

(2020) Jhon Cores et al.   Stem Cells Translational Medicine

3D Printed Biomodels for Flow Visualization in Stenotic Vessels: An Experimental and Numerical Study

(2020) Violeta Carvalho et al.   Micromachines

Organoids as a Powerful Model for Respiratory Diseases

(2020) Yu Li et al.   Stem Cells International

Deposition Mechanisms

(2020) Chantal Darquenne   Journal of Aerosol Medicine and Pulmonary Drug Delivery

Modeling neoplastic disease with spheroids and organoids

(2020) Michele Zanoni et al.   Journal of Hematology & Oncology

Nanotoxicology: The Need for a Human Touch?

(2020) Mark R. Miller et al.   Small

Differences in cytotoxicity of lung epithelial cells exposed to titanium dioxide nanofibers and nanoparticles: Comparison of air-liquid interface and submerged cell cultures

(2020) Estefany I. Medina-Reyes et al.   TOXICOLOGY IN VITRO

In vitro Alternatives to Acute Inhalation Toxicity Studies in Animal Models—A Perspective

(2020) Dania Movia et al.   Frontiers in Bioengineering and Biotechnology

Impact of Culture Medium on Cellular Interactions in in vitro Co-culture Systems

(2020) Michelle A. M. Vis et al.   Frontiers in Bioengineering and Biotechnology

Quartz crystal microbalances (QCM) are suitable for real-time dosimetry in nanotoxicological studies using VITROCELL®Cloud cell exposure systems

(2020) Yaobo Ding et al.   Particle and Fibre Toxicology

A Human-Relevant 3D In Vitro Platform for an Effective and Rapid Simulation of Workplace Exposure to Nanoparticles: Silica Nanoparticles as Case Study

(2020) Luisana Di Cristo et al.   Nanomaterials

A molecular cell atlas of the human lung from single-cell RNA sequencing

(2020) Kyle J. Travaglini et al.   NATURE

Air–Liquid Interface Exposure of Lung Epithelial Cells to Low Doses of Nanoparticles to Assess Pulmonary Adverse Effects

(2020) Silvia Diabaté et al.   Nanomaterials

Nanomaterials in the environment, human exposure pathway, and health effects: A review

(2020) Arindam Malakar et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Engineered nanoparticle exposure and cardiovascular effects: the role of a neuronal-regulated pathway

(2019) H. Kan et al.   INHALATION TOXICOLOGY

In vitro and in vivo characterization of pharmaceutical nanocarriers used for drug delivery

(2019) Akhlesh K. Jain et al.   Artificial Cells Nanomedicine and Biotechnology

Nanoparticle administration method in cell culture alters particle-cell interaction

(2019) Thomas L. Moore et al.   Scientific Reports

A health concern regarding the protein corona, aggregation and disaggregation

(2019) Mojtaba Falahati et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

In vitro exposure of a 3D-tetraculture representative for the alveolar barrier at the air-liquid interface to silver particles and nanowires

(2019) Ionel Fizeșan et al.   Particle and Fibre Toxicology

A novel human 3D lung microtissue model for nanoparticle-induced cell-matrix alterations

(2019) Pranita K. Kabadi et al.   Particle and Fibre Toxicology

Toxicological effects of ambient fine (PM2.5-0.18) and ultrafine (PM0.18) particles in healthy and diseased 3D organo-typic mucocilary-phenotype models

(2019) J. Sotty et al.   ENVIRONMENTAL RESEARCH

Toxicological Assessment of ITER-Like Tungsten Nanoparticles Using an In Vitro 3D Human Airway Epithelium Model

(2019) Isabelle George et al.   Nanomaterials

Differential pulmonary in vitro toxicity of two small-sized polyvinylpyrrolidone-coated silver nanoparticles

(2018) Fernanda Rosário et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Nanofiber membrane supported lung-on-a-chip microdevice for anti-cancer drug testing

(2018) Xingyuan Yang et al.   LAB ON A CHIP

The small airway epithelium as a target for the adverse pulmonary effects of silver nanoparticle inhalation

(2018) Chang Guo et al.   Nanotoxicology

ISD3: a particokinetic model for predicting the combined effects of particle sedimentation, diffusion and dissolution on cellular dosimetry for in vitro systems

(2018) Dennis G. Thomas et al.   Particle and Fibre Toxicology

Predicting the in vivo pulmonary toxicity induced by acute exposure to poorly soluble nanomaterials by using advanced in vitro methods

(2018) Thomas Loret et al.   Particle and Fibre Toxicology

Air-Liquid Interface: Relevant In Vitro Models for Investigating Air Pollutant-Induced Pulmonary Toxicity

(2018) Swapna Upadhyay et al.   TOXICOLOGICAL SCIENCES

Alternative approaches for acute inhalation toxicity testing to address global regulatory and non-regulatory data requirements: An international workshop report

(2018) Amy J. Clippinger et al.   TOXICOLOGY IN VITRO

Human lung epithelial cell cultures for analysis of inhaled toxicants: Lessons learned and future directions

(2018) Pieter S. Hiemstra et al.   TOXICOLOGY IN VITRO

Nanomaterial exposure, toxicity, and impact on human health

(2018) Antonio Pietroiusti et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Comparison of conventional and advanced in vitro models in the toxicity testing of nanoparticles

(2018) Eleonore Fröhlich   Artificial Cells Nanomedicine and Biotechnology

The impact of nanomaterial characteristics on inhalation toxicity

(2018) Frank S. Bierkandt et al.   Toxicology Research

Three-Dimensional in Vitro Cell Culture Models in Drug Discovery and Drug Repositioning

(2018) Sigrid A. Langhans   Frontiers in Pharmacology

In Vitro Induction and In Vivo Engraftment of Lung Bud Tip Progenitor Cells Derived from Human Pluripotent Stem Cells

(2018) Alyssa J. Miller et al.   Stem Cell Reports

Nanotechnology: current uses and future applications in the food industry

(2018) Muthu Thiruvengadam et al.   3 Biotech

Nanotechnology: current uses and future applications in the food industry

(2018) Muthu Thiruvengadam et al.   3 Biotech

Use of 3D organoids and lung-on-a-chip methods to study lung development, regeneration and disease

(2018) Konstantinos Gkatzis et al.   EUROPEAN RESPIRATORY JOURNAL

Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor

(2018) William J. Zacharias et al.   NATURE

OncoCilAir™: A physiological in vitro platform to assess the efficacy and the toxicity of lung cancer therapeutics

(2018) H. Benainous et al.   TOXICOLOGY LETTERS

Altered deposition of inhaled nanoparticles in subjects with chronic obstructive pulmonary disease

(2018) Jonas K F Jakobsson et al.   BMC Pulmonary Medicine

A 3D human lung-on-a-chip model for nanotoxicity testing

(2018) Min Zhang et al.   Toxicology Research

Ambient fine particulate matter induce toxicity in lung epithelial-endothelial co-culture models

(2018) Guanghe Wang et al.   TOXICOLOGY LETTERS

Assessing the translocation of silver nanoparticles using an in vitro co-culture model of human airway barrier

(2018) Fan Zhang et al.   TOXICOLOGY IN VITRO

Nanomaterials Versus Ambient Ultrafine Particles: An Opportunity to Exchange Toxicology Knowledge

(2017) Vicki Stone et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

A Novel Exposure System Termed NAVETTA for In Vitro Laminar Flow Electrodeposition of Nanoaerosol and Evaluation of Immune Effects in Human Lung Reporter Cells

(2017) Evelien Frijns et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

A practical approach to assess inhalation toxicity of metal oxide nanoparticles in vitro

(2017) Anita C. A. Dankers et al.   JOURNAL OF APPLIED TOXICOLOGY

A three-dimensional model of human lung development and disease from pluripotent stem cells

(2017) Ya-Wen Chen et al.   NATURE CELL BIOLOGY

Long-term expansion of alveolar stem cells derived from human iPS cells in organoids

(2017) Yuki Yamamoto et al.   NATURE METHODS

On the pivotal role of dose for particle toxicology and risk assessment: exposure is a poor surrogate for delivered dose

(2017) Otmar Schmid et al.   Particle and Fibre Toxicology

Nanoparticles and innate immunity: new perspectives on host defence

(2017) Diana Boraschi et al.   SEMINARS IN IMMUNOLOGY

Factors of concern in a human 3D cellular airway model exposed to aerosols of nanoparticles

(2017) Ingeborg M. Kooter et al.   TOXICOLOGY IN VITRO

Co-culture of human alveolar epithelial (hAELVi) and macrophage (THP-1) cell lines

(2017) Stephanie Kletting   ALTEX-Alternatives to Animal Experimentation

Toxicity Research of PM2.5 Compositions In Vitro

(2017) Yi-Yang Jia et al.   International Journal of Environmental Research and Public Health

Expert consensus on an in vitro approach to assess pulmonary fibrogenic potential of aerosolized nanomaterials

(2016) Amy J. Clippinger et al.   ARCHIVES OF TOXICOLOGY

Plasmonic nanoparticles and their characterization in physiological fluids

(2016) Dominic A. Urban et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Methodological considerations when conducting in vitro, air–liquid interface exposures to engineered nanoparticle aerosols

(2016) Lynn E. Secondo et al.   CRITICAL REVIEWS IN TOXICOLOGY

In Vitro Pulmonary Cell Culture in Pharmaceutical Inhalation Aerosol Delivery: 2-D, 3-D, and In Situ Bioimpactor Models

(2016) Maria F. Acosta et al.   CURRENT PHARMACEUTICAL DESIGN

Three-dimensional models for studying development and disease: moving on from organisms to organs-on-a-chip and organoids

(2016) E. L. Jackson et al.   Integrative Biology

A work group report on ultrafine particles (American Academy of Allergy, Asthma & Immunology): Why ambient ultrafine and engineered nanoparticles should receive special attention for possible adverse health outcomes in human subjects

(2016) Ning Li et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Differential toxicity of an organic PM2.5extract to human lung cells cultured in three dimensions (3D) and monolayers

(2016) Elisa Raquel A. Ferraz et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

A Multilaboratory Toxicological Assessment of a Panel of 10 Engineered Nanomaterials to Human Health—ENPRA Project—The Highlights, Limitations, and Current and Future Challenges

(2016) Ali Kermanizadeh et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

Gold nanoparticles: A critical review of therapeutic applications and toxicological aspects

(2016) Maria Fernanda Hornos Carneiro et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

A paper-based in vitro model for on-chip investigation of the human respiratory system

(2016) Rahim Rahimi et al.   LAB ON A CHIP

Currentin vitroapproaches to assess nanoparticle interactions with lung cells

(2016) Kleanthis Fytianos et al.   Nanomedicine

Influence of agglomeration and specific lung lining lipid/protein interaction on short-term inhalation toxicity

(2016) Wendel Wohlleben et al.   Nanotoxicology

Air-liquid interface exposure to aerosols of poorly soluble nanomaterials induces different biological activation levels compared to exposure to suspensions

(2016) Thomas Loret et al.   Particle and Fibre Toxicology

Grouping nanomaterials to predict their potential to induce pulmonary inflammation

(2016) Hedwig M. Braakhuis et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Development of a Three-Dimensional Bioengineering Technology to Generate Lung Tissue for Personalized Disease Modeling

(2016) Dan C. Wilkinson et al.   Stem Cells Translational Medicine

An in vitro alveolar macrophage assay for predicting the short-term inhalation toxicity of nanomaterials

(2016) Martin Wiemann et al.   JOURNAL OF NANOBIOTECHNOLOGY

Modeling Barrier Tissues In Vitro: Methods, Achievements, and Challenges

(2016) Courtney M. Sakolish et al.   EBioMedicine

Proteomic and Lipidomic Analysis of Nanoparticle Corona upon Contact with Lung Surfactant Reveals Differences in Protein, but Not Lipid Composition

(2015) Simon Sebastian Raesch et al.   ACS Nano

Progress and future of in vitro models to study translocation of nanoparticles

(2015) Hedwig M. Braakhuis et al.   ARCHIVES OF TOXICOLOGY

Nanoparticle colloidal stability in cell culture media and impact on cellular interactions

(2015) Thomas L. Moore et al.   CHEMICAL SOCIETY REVIEWS

The nanoparticle biomolecule corona: lessons learned – challenge accepted?

(2015) D. Docter et al.   CHEMICAL SOCIETY REVIEWS

Air pollution and public health: emerging hazards and improved understanding of risk

(2015) Frank J. Kelly et al.   ENVIRONMENTAL GEOCHEMISTRY AND HEALTH

The innate immune function of airway epithelial cells in inflammatory lung disease

(2015) Pieter S. Hiemstra et al.   EUROPEAN RESPIRATORY JOURNAL

A biologically inspired lung-on-a-chip device for the study of protein-induced lung inflammation

(2015) Tushar H. Punde et al.   Integrative Biology

Particle deposition efficiency at air–liquid interface of a cell exposure chamber

(2015) Yuji Fujitani et al.   JOURNAL OF AEROSOL SCIENCE

Three dimensional spheroid cell culture for nanoparticle safety testing

(2015) Franziska Sambale et al.   JOURNAL OF BIOTECHNOLOGY

Inhalation Exposure to Carbon Nanotubes (CNT) and Carbon Nanofibers (CNF): Methodology and Dosimetry

(2015) Günter Oberdörster et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

A lung-on-a-chip array with an integrated bio-inspired respiration mechanism

(2015) Andreas O. Stucki et al.   LAB ON A CHIP

Nanoparticle uptake: The phagocyte problem

(2015) Heather Herd Gustafson et al.   Nano Today

Repeated exposure to carbon nanotube-based aerosols does not affect the functional properties of a 3D human epithelial airway model

(2015) Savvina Chortarea et al.   Nanotoxicology

Respiratory epithelial cells orchestrate pulmonary innate immunity

(2015) Jeffrey A Whitsett et al.   NATURE IMMUNOLOGY

Aerosol generation and characterization of multi-walled carbon nanotubes exposed to cells cultured at the air-liquid interface

(2015) William W. Polk et al.   Particle and Fibre Toxicology

Toxicity assessment of aggregated/agglomerated cerium oxide nanoparticles in an in vitro 3D airway model: The influence of mucociliary clearance

(2015) C. Frieke Kuper et al.   TOXICOLOGY IN VITRO

Development of an in vitro model of human bronchial epithelial barrier to study nanoparticle translocation

(2015) Isabelle George et al.   TOXICOLOGY IN VITRO

Toxicity of nanoparticles embedded in paints compared to pristine nanoparticles, in vitro study

(2015) Stijn Smulders et al.   TOXICOLOGY LETTERS

The oxidative potential of differently charged silver and gold nanoparticles on three human lung epithelial cell types

(2015) Paul Schlinkert et al.   JOURNAL OF NANOBIOTECHNOLOGY

Particulate Matter from Both Heavy Fuel Oil and Diesel Fuel Shipping Emissions Show Strong Biological Effects on Human Lung Cells at Realistic and Comparable In Vitro Exposure Conditions

(2015) Sebastian Oeder et al.   PLoS One

Temporal Monitoring of Differentiated Human Airway Epithelial Cells Using Microfluidics

(2015) Cornelia Blume et al.   PLoS One

Three-Dimensional Cell Culture Systems and Their Applications in Drug Discovery and Cell-Based Biosensors

(2014) Rasheena Edmondson et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Toxicological Assessment of Inhaled Nanoparticles: Role of in Vivo, ex Vivo, in Vitro, and in Silico Studies

(2014) Eleonore Fröhlich et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Co-culture systems and technologies: taking synthetic biology to the next level

(2014) L. Goers et al.   Journal of the Royal Society Interface

Nano Aerosol Chamber forIn-VitroToxicity (NACIVT) studies

(2014) Natalie Jeannet et al.   Nanotoxicology

Physicochemical characteristics of nanomaterials that affect pulmonary inflammation

(2014) Hedwig M Braakhuis et al.   Particle and Fibre Toxicology

Nanoparticle growth and surface chemistry changes in cell-conditioned culture medium

(2014) M. Kendall et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Silica nanoparticles are less toxic to human lung cells when deposited at the air–liquid interface compared to conventional submerged exposure

(2014) Alicja Panas et al.   Beilstein Journal of Nanotechnology

Generation of Alveolar Epithelial Spheroids via Isolated Progenitor Cells from Human Pluripotent Stem Cells

(2014) Shimpei Gotoh et al.   Stem Cell Reports

Nanoparticle diffusion in respiratory mucus from humans without lung disease

(2013) Benjamin S. Schuster et al.   BIOMATERIALS

Assessing nanoparticle toxicity in cell-based assays: influence of cell culture parameters and optimized models for bridging the in vitro–in vivo gap

(2013) Freya Joris et al.   CHEMICAL SOCIETY REVIEWS

In vitro, in vivo and ex vivo models for studying particle deposition and drug absorption of inhaled pharmaceuticals

(2013) Kamrun Nahar et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Measurement Techniques for Respiratory Tract Deposition of Airborne Nanoparticles: A Critical Review

(2013) Jakob Löndahl et al.   Journal of Aerosol Medicine and Pulmonary Drug Delivery

Nanoparticle Mass Transfer From Lung Airways to Systemic Regions—Part I: Whole-Lung Aerosol Dynamics

(2013) Arun V. Kolanjiyil et al.   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

An improved 3D tetraculture system mimicking the cellular organisation at the alveolar barrier to study the potential toxic effects of particles on the lung

(2013) Sebastian G Klein et al.   Particle and Fibre Toxicology

Growth of human bronchial epithelial cells at an air-liquid interface alters the response to particle exposure

(2013) Andrew J Ghio et al.   Particle and Fibre Toxicology

Evaluation of Nanoparticle Uptake in Co-culture Cancer Models

(2013) Elisabete C. Costa et al.   PLoS One

A revised model for the deposition and clearance of inhaled particles in human extra-thoracic airways

(2013) J. R. H. Smith et al.   RADIATION PROTECTION DOSIMETRY

Particle size and pathogenicity in the respiratory tract

(2013) Richard James Thomas   Virulence

Inflammatory and Oxidative Stress Responses of an Alveolar Epithelial Cell Line to Airborne Zinc Oxide Nanoparticles at the Air-Liquid Interface: A Comparison with Conventional, Submerged Cell-Culture Conditions

(2013) Anke-Gabriele Lenz et al.   Biomed Research International

Recent Advances in Particulate Matter and Nanoparticle Toxicology: A Review of theIn VivoandIn VitroStudies

(2013) Abderrahim Nemmar et al.   Biomed Research International

In vitro and in vivo evaluation of a dry powder endotracheal insufflator device for use in dose-dependent preclinical studies in mice

(2012) Christophe Duret et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Manufactured and airborne nanoparticle cardiopulmonary interactions: a review of mechanisms and the possible contribution of mast cells

(2012) Jonathan H. Shannahan et al.   INHALATION TOXICOLOGY

Nanoparticles: a review of particle toxicology following inhalation exposure

(2012) Shahnaz Bakand et al.   INHALATION TOXICOLOGY

Building and maintaining the epithelium of the lung

(2012) Craig R. Rackley et al.   JOURNAL OF CLINICAL INVESTIGATION

New Perspectives for in Vitro Risk Assessment of Multiwalled Carbon Nanotubes: Application of Coculture and Bioinformatics

(2012) Brandi N. Snyder-Talkington et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

Biomolecular coronas provide the biological identity of nanosized materials

(2012) Marco P. Monopoli et al.   Nature Nanotechnology

Health impact and toxicological effects of nanomaterials in the lung

(2012) MICHAELA KENDALL et al.   RESPIROLOGY

Effect of Nanoparticles and Environmental Particles on a Cocultures Model of the Air-Blood Barrier

(2012) Rossella Bengalli et al.   Biomed Research International

Nanoparticle-induced pulmonary toxicity

(2011) Jasmine Jia'en Li et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

In-vitro cell exposure studies for the assessment of nanoparticle toxicity in the lung—A dialog between aerosol science and biology

(2011) Hanns-Rudolf Paur et al.   JOURNAL OF AEROSOL SCIENCE

Physical−Chemical Aspects of Protein Corona: Relevance toin Vitroandin VivoBiological Impacts of Nanoparticles

(2011) Marco P. Monopoli et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Toxicology of Nanomaterials Used in Nanomedicine

(2011) Jinshun Zhao et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

Tissue-Specific Stem Cell Differentiation in an in vitro Airway Model

(2011) Zoë Prytherch et al.   MACROMOLECULAR BIOSCIENCE

Inflammatory and cytotoxic responses of an alveolar-capillary coculture model to silica nanoparticles: Comparison with conventional monocultures

(2011) Jennifer Kasper et al.   Particle and Fibre Toxicology

Respiratory effects of manufactured nanoparticles

(2011) P. Andujar et al.   REVUE DES MALADIES RESPIRATOIRES

Endotoxin as modifier of particulate matter toxicity: a review of the literature

(2010) Cristiane Degobbi et al.   AEROBIOLOGIA

The air-liquid interface and use of primary cell cultures are important to recapitulate the transcriptional profile of in vivo airway epithelia

(2010) Alejandro A. Pezzulo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Do Airway Epithelium Air–Liquid Cultures Represent theIn VivoAirway Epithelium Transcriptome?

(2010) Anna Dvorak et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Drug delivery and nanoparticles: Applications and hazards

(2010) de Jong   International Journal of Nanomedicine

Update on Macrophage Clearance of Inhaled Micro- and Nanoparticles

(2010) Marianne Geiser   Journal of Aerosol Medicine and Pulmonary Drug Delivery

ISDD: A computational model of particle sedimentation, diffusion and target cell dosimetry for in vitro toxicity studies

(2010) Paul M Hinderliter et al.   Particle and Fibre Toxicology

Reconstituting Organ-Level Lung Functions on a Chip

(2010) D. Huh et al.   SCIENCE

Risk assessment of engineered nanomaterials and nanotechnologies—A review

(2010) Kai Savolainen et al.   TOXICOLOGY

Airflow and Particle Transport in the Human Respiratory System

(2009) C. Kleinstreuer et al.   Annual Review of Fluid Mechanics

A dose-controlled system for air-liquid interface cell exposure and application to zinc oxide nanoparticles

(2009) Anke Lenz et al.   Particle and Fibre Toxicology

In vitromodels of the human epithelial airway barrier to study the toxic potential of particulate matter

(2008) Barbara Rothen-Rutishauser et al.   Expert Opinion on Drug Metabolism & Toxicology

Design and Testing of Electrostatic AerosolIn VitroExposure System (EAVES): An Alternative Exposure System for Particles

(2008) K. de Bruijne et al.   INHALATION TOXICOLOGY