A three-dimensional model of human lung development and disease from pluripotent stem cells

Viral bronchiolitis

(2017) Todd A Florin et al.   LANCET

A bioengineered niche promotes in vivo engraftment and maturation of pluripotent stem cell derived human lung organoids

(2016) Briana R Dye et al.   eLife

Lost after translation: insights from pulmonary surfactant for understanding the role of alveolar epithelial dysfunction and cellular quality control in fibrotic lung disease

(2015) Surafel Mulugeta et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Diseases of Pulmonary Surfactant Homeostasis

(2015) Jeffrey A. Whitsett et al.   Annual Review of Pathology-Mechanisms of Disease

The in vitro generation of lung and airway progenitor cells from human pluripotent stem cells

(2015) Sarah X L Huang et al.   Nature Protocols

Life-threatening influenza and impaired interferon amplification in human IRF7 deficiency

(2015) M. J. Ciancanelli et al.   SCIENCE

Plasticity of Hopx+ type I alveolar cells to regenerate type II cells in the lung

(2015) Rajan Jain et al.   Nature Communications

Hox5 Genes Regulate the Wnt2/2b-Bmp4-Signaling Axis during Lung Development

(2015) Steven M. Hrycaj et al.   Cell Reports

In vitro generation of human pluripotent stem cell derived lung organoids

(2015) Briana R Dye et al.   eLife

KeyGenes, a Tool to Probe Tissue Differentiation Using a Human Fetal Transcriptional Atlas

(2015) Matthias S. Roost et al.   Stem Cell Reports

Lung development: orchestrating the generation and regeneration of a complex organ

(2014) M. Herriges et al.   DEVELOPMENT

RSV-encoded NS2 promotes epithelial cell shedding and distal airway obstruction

(2014) Rachael M. Liesman et al.   JOURNAL OF CLINICAL INVESTIGATION

Idiopathic Pulmonary Fibrosis: Evolving Concepts

(2014) Jay H. Ryu et al.   MAYO CLINIC PROCEEDINGS

Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq

(2014) Barbara Treutlein et al.   NATURE

Defining a mesenchymal progenitor niche at single-cell resolution

(2014) M. E. Kumar et al.   SCIENCE

Organogenesis in a dish: Modeling development and disease using organoid technologies

(2014) M. A. Lancaster et al.   SCIENCE

Hedgehog Signaling in Neonatal and Adult Lung

(2013) Li Liu et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Coordination of heart and lung co-development by a multipotent cardiopulmonary progenitor

(2013) Tien Peng et al.   NATURE

Efficient generation of lung and airway epithelial cells from human pluripotent stem cells

(2013) Sarah X L Huang et al.   NATURE BIOTECHNOLOGY

Sox9 plays multiple roles in the lung epithelium during branching morphogenesis

(2013) B. E. Rockich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Alveolar Epithelium Determines Susceptibility to Lung Fibrosis in Hermansky-Pudlak Syndrome

(2012) Lisa R. Young et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Spatial mapping and quantification of developmental branching morphogenesis

(2012) K. Short et al.   DEVELOPMENT

Recent advances and contraversies on the role of pulmonary neuroepithelial bodies as airway sensors

(2012) Ernest Cutz et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Telomerase and idiopathic pulmonary fibrosis

(2011) Mary Armanios   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Generation of anterior foregut endoderm from human embryonic and induced pluripotent stem cells

(2011) Michael D Green et al.   NATURE BIOTECHNOLOGY

Preparing for the First Breath: Genetic and Cellular Mechanisms in Lung Development

(2010) Edward E. Morrisey et al.   DEVELOPMENTAL CELL

Disorders of Lysosome-Related Organelle Biogenesis: Clinical and Molecular Genetics

(2008) Marjan Huizing et al.   Annual Review of Genomics and Human Genetics