Toxicological Assessment of Inhaled Nanoparticles: Role of in Vivo, ex Vivo, in Vitro, and in Silico Studies

Statins Reduce Ambient Particulate Matter-Induced Lung Inflammation by Promoting the Clearance of Particulate Matter < 10 μm From Lung Tissues

(2013) Ryohei Miyata et al.   CHEST

Alteration of biophysical activity of pulmonary surfactant by aluminosilicate nanoparticles

(2013) Dorota Kondej et al.   INHALATION TOXICOLOGY

Measurement Techniques for Respiratory Tract Deposition of Airborne Nanoparticles: A Critical Review

(2013) Jakob Löndahl et al.   Journal of Aerosol Medicine and Pulmonary Drug Delivery

Predictive Toxicology of cobalt ferrite nanoparticles: comparative in-vitro study of different cellular models using methods of knowledge discovery from data

(2013) Limor Horev-Azaria et al.   Particle and Fibre Toxicology

An improved 3D tetraculture system mimicking the cellular organisation at the alveolar barrier to study the potential toxic effects of particles on the lung

(2013) Sebastian G Klein et al.   Particle and Fibre Toxicology

In vivo–in vitro comparison of acute respiratory tract toxicity using human 3D airway epithelial models and human A549 and murine 3T3 monolayer cell systems

(2012) Ursula G. Sauer et al.   TOXICOLOGY IN VITRO

Comparison of two in vitro systems to assess cellular effects of nanoparticles-containing aerosols

(2012) Eleonore Fröhlich et al.   TOXICOLOGY IN VITRO

Milan PM1 Induces Adverse Effects on Mice Lungs and Cardiovascular System

(2012) Francesca Farina et al.   Biomed Research International

In silico models of aerosol delivery to the respiratory tract — Development and applications

(2011) P. Worth Longest et al.   ADVANCED DRUG DELIVERY REVIEWS

Dendritic cell functional properties in a three-dimensional tissue model of human lung mucosa

(2011) Anh Thu Nguyen Hoang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Analytical in vitro approach for studying cyto- and genotoxic effects of particulate airborne material

(2011) Michaela Aufderheide et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Health effects of particulate air pollution: A review of epidemiological evidence

(2011) Regina Rückerl et al.   INHALATION TOXICOLOGY

Modelling inhaled particle deposition in the human lung—A review

(2011) Werner Hofmann   JOURNAL OF AEROSOL SCIENCE

Nanoparticle exposure at nanotechnology workplaces: A review

(2011) Thomas AJ Kuhlbusch et al.   Particle and Fibre Toxicology

Potential of coculture in vitro models to study inflammatory and sensitizing effects of particles on the lung

(2011) Sebastian G. Klein et al.   TOXICOLOGY IN VITRO

From 3D cell culture to organs-on-chips

(2011) Dongeun Huh et al.   TRENDS IN CELL BIOLOGY

Cellular Responses after Exposure of Lung Cell Cultures to Secondary Organic Aerosol Particles

(2010) Annina Gaschen et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Deposition and biokinetics of inhaled nanoparticles

(2010) Marianne Geiser et al.   Particle and Fibre Toxicology

Quantitative Evaluation of Cellular Uptake and Trafficking of Plain and Polyethylene Glycol-Coated Gold Nanoparticles

(2010) Christina Brandenberger et al.   Small

Human primary bronchial lung cell constructs: The new respiratory models

(2010) Kelly BéruBé et al.   TOXICOLOGY

Direct Combination of Nanoparticle Fabrication and Exposure to Lung Cell Cultures in a Closed Setup as a Method To Simulate Accidental Nanoparticle Exposure of Humans

(2009) Barbara Rothen-Rutishauser et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Direct Particle-to-Cell Deposition of Coarse Ambient Particulate Matter Increases the Production of Inflammatory Mediators from Cultured Human Airway Epithelial Cells

(2009) John Volckens et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

The Impact of Toxicity Testing Costs on Nanomaterial Regulation

(2009) Jae-Young Choi et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Exposure to nanoparticles is related to pleural effusion, pulmonary fibrosis and granuloma

(2009) Y. Song et al.   EUROPEAN RESPIRATORY JOURNAL

Low cytotoxicity of solid lipid nanoparticles inin vitroandex vivolung models

(2009) Matthias Nassimi et al.   INHALATION TOXICOLOGY

Size dependence of the translocation of inhaled iridium and carbon nanoparticle aggregates from the lung of rats to the blood and secondary target organs

(2009) Wolfgang G. Kreyling et al.   INHALATION TOXICOLOGY

Nanoparticles and the Brain: Cause for Concern?

(2009) Günter Oberdörster et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Cells on Pores: A Simulation-Driven Analysis of Transcellular Small Molecule Transport

(2009) Xinyuan Zhang et al.   MOLECULAR PHARMACEUTICS

Toxic effects of brake wear particles on epithelial lung cells in vitro

(2009) Michael Gasser et al.   Particle and Fibre Toxicology

A dose-controlled system for air-liquid interface cell exposure and application to zinc oxide nanoparticles

(2009) Anke Lenz et al.   Particle and Fibre Toxicology

Effects and uptake of gold nanoparticles deposited at the air–liquid interface of a human epithelial airway model

(2009) C. Brandenberger et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Inhalation vs. aspiration of single-walled carbon nanotubes in C57BL/6 mice: inflammation, fibrosis, oxidative stress, and mutagenesis

(2008) A. A. Shvedova et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Update in Occupational and Environmental Respiratory Disease 2007

(2008) Tim S. Nawrot et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Prospective Analysis of Traffic Exposure as a Risk Factor for Incident Coronary Heart Disease: The Atherosclerosis Risk in Communities (ARIC) Study

(2008) Haidong Kan et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

A Novel Exposure System for the Efficient and Controlled Deposition of Aerosol Particles onto Cell Cultures

(2008) Melanie Savi et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Co-cultures of multiple cell types mimic pulmonary cell communication in response to urban PM10

(2008) E. Alfaro-Moreno et al.   EUROPEAN RESPIRATORY JOURNAL

In vitromodels of the human epithelial airway barrier to study the toxic potential of particulate matter

(2008) Barbara Rothen-Rutishauser et al.   Expert Opinion on Drug Metabolism & Toxicology

Design and Testing of Electrostatic AerosolIn VitroExposure System (EAVES): An Alternative Exposure System for Particles

(2008) K. de Bruijne et al.   INHALATION TOXICOLOGY

In Vitro Exposure Systems and Bioassays for the Assessment of Toxicity of Nanoparticles to the Human Lung

(2008) Hanns.-R. Paur et al.   Journal fur Verbraucherschutz und Lebensmittelsicherheit-Journal of Consumer Protection and Food Safety

Comparison of analytical and CFD models with regard to micron particle deposition in a human 16-generation tracheobronchial airway model

(2008) Zhe Zhang et al.   JOURNAL OF AEROSOL SCIENCE

Pulmonary response to intratracheal instillation of ultrafine versus fine titanium dioxide: role of particle surface area

(2008) Tina M Sager et al.   Particle and Fibre Toxicology

Canine models of asthma and COPD

(2008) Richard W. Chapman   PULMONARY PHARMACOLOGY & THERAPEUTICS

Effects of dynamic compression on lentiviral transduction in an in vitro airway wall model

(2007) Alice A. Tomei et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY