Recent Advances in Particulate Matter and Nanoparticle Toxicology: A Review of theIn VivoandIn VitroStudies

Particle size, chemical composition, seasons of the year and urban, rural or remote site origins as determinants of biological effects of particulate matter on pulmonary cells

(2013) M.G. Perrone et al.   ENVIRONMENTAL POLLUTION

A Meta-Analysis and Multisite Time-Series Analysis of the Differential Toxicity of Major Fine Particulate Matter Constituents

(2012) Jonathan I. Levy et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Interaction of Diesel Exhaust Particles with Human, Rat and Mouse Erythrocytes in Vitro

(2012) Abderrahim Nemmar et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

TiO2 Nanoparticles Induce Dysfunction and Activation of Human Endothelial Cells

(2012) Angélica Montiel-Dávalos et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Epigenetics mediate environment

(2012) Karin A. Pacheco   Current Opinion in Allergy and Clinical Immunology

DNA repair as a biomarker

(2012) Andrew R. Collins et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Diesel exhaust increases EGFR and phosphorylated C-terminal Tyr 1173 in the bronchial epithelium

(2012) Jamshid Pourazar et al.   Particle and Fibre Toxicology

Protective Effect of Curcumin on Pulmonary and Cardiovascular Effects Induced by Repeated Exposure to Diesel Exhaust Particles in Mice

(2012) Abderrahim Nemmar et al.   PLoS One

Thrombogenic changes in young and old mice upon subchronic exposure to air pollution in an urban roadside tunnel

(2012) Jan Emmerechts et al.   THROMBOSIS AND HAEMOSTASIS

Season linked responses to fine and quasi-ultrafine Milan PM in cultured cells

(2012) E. Longhin et al.   TOXICOLOGY IN VITRO

Genotoxic potential of organic extracts from particle emissions of diesel and rapeseed oil powered engines

(2012) Jan Topinka et al.   TOXICOLOGY LETTERS

Influence of experimental type 1 diabetes on the pulmonary effects of diesel exhaust particles in mice

(2012) Abderrahim Nemmar et al.   TOXICOLOGY LETTERS

Pulmonary T cell activation in response to chronic particulate air pollution

(2011) Jeffrey A. Deiuliis et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Effects of Carbon Black Nanoparticles on Elastase-Induced Emphysematous Lung Injury in Mice

(2011) Ken-ichiro Inoue et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Contrasting actions of diesel exhaust particles on the pulmonary and cardiovascular systems and the effects of thymoquinone

(2011) Abderrahim Nemmar et al.   BRITISH JOURNAL OF PHARMACOLOGY

Asthma and lung cancer risk: a systematic investigation by the International Lung Cancer Consortium

(2011) Albert Rosenberger et al.   CARCINOGENESIS

Chronic Fine Particulate Matter Exposure Induces Systemic Vascular Dysfunction via NADPH Oxidase and TLR4 Pathways

(2011) Thomas Kampfrath et al.   CIRCULATION RESEARCH

The oxidative potential and biological effects induced by PM10 obtained in Mexico City and at a receptor site during the MILAGRO Campaign

(2011) Raul Quintana et al.   ENVIRONMENTAL POLLUTION

TACE/TGF- /EGFR regulates CXCL8 in bronchial epithelial cells exposed to particulate matter components

(2011) J. Ovrevik et al.   EUROPEAN RESPIRATORY JOURNAL

Nanoparticle-induced pulmonary toxicity

(2011) Jasmine Jia'en Li et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Low dose of fine particulate matter (PM2.5) can induce acute oxidative stress, inflammation and pulmonary impairment in healthy mice

(2011) D.R. Riva et al.   INHALATION TOXICOLOGY

Simvastatin pretreatment prevents ambient particle-induced lung injury in mice

(2011) Sebastian A. Ferraro et al.   INHALATION TOXICOLOGY

Eugenol attenuates pulmonary damage induced by diesel exhaust particles

(2011) Walter A. Zin et al.   JOURNAL OF APPLIED PHYSIOLOGY

Polycyclic aromatic hydrocarbons within airborne particulate matter (PM2.5) produced DNA bulky stable adducts in a human lung cell coculture model

(2011) Imane Abbas et al.   JOURNAL OF APPLIED TOXICOLOGY

Airborne urban particles (Milan winter-PM2.5) cause mitotic arrest and cell death: Effects on DNA, mitochondria, AhR binding and spindle organization

(2011) Maurizio Gualtieri et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Organic extracts of urban air pollution particulate matter (PM2.5)-induced genotoxicity and oxidative stress in human lung bronchial epithelial cells (BEAS-2B cells)

(2011) Seung Min Oh et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Neurological impacts from inhalation of pollutants and the nose–brain connection

(2011) R.G. Lucchini et al.   NEUROTOXICOLOGY

Effects of copper nanoparticle exposure on host defense in a murine pulmonary infection model

(2011) Jong Sung Kim et al.   Particle and Fibre Toxicology

Particulate Matter-Induced Lung Inflammation Increases Systemic Levels of PAI-1 and Activates Coagulation Through Distinct Mechanisms

(2011) G. R. Scott Budinger et al.   PLoS One

Importance of Plasma Membrane Dynamics in Chemical-Induced Carcinogenesis

(2011) Xavier Tekpli et al.   Recent Patents on Anti-Cancer Drug Discovery

Chronic Obstructive Pulmonary Disease and Lung Cancer: New Molecular Insights

(2011) Ian M. Adcock et al.   RESPIRATION

Exacerbation of thrombotic events by diesel exhaust particle in mouse model of hypertension

(2011) Abderrahim Nemmar et al.   TOXICOLOGY

Airway resistance, inflammation and oxidative stress following exposure to diesel exhaust particle in angiotensin II-induced hypertension in mice

(2011) Abderrahim Nemmar et al.   TOXICOLOGY

DNA adducts and oxidative DNA damage induced by organic extracts from PM2.5 in an acellular assay

(2011) Jan Topinka et al.   TOXICOLOGY LETTERS

Differential effects of the particle core and organic extract of diesel exhaust particles

(2011) Annike Irene Totlandsdal et al.   TOXICOLOGY LETTERS

Chemokines

(2010) Steven M. Dubinett et al.   CANCER JOURNAL

Particulate Matter Air Pollution and Cardiovascular Disease

(2010) Robert D. Brook et al.   CIRCULATION

Long-Term Inhalation Exposure to Nickel Nanoparticles Exacerbated Atherosclerosis in a Susceptible Mouse Model

(2010) Gi Soo Kang et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Subchronic effects of nasally instilled diesel exhaust particulates on the nasal and airway epithelia in mice

(2010) K. Yoshizaki et al.   INHALATION TOXICOLOGY

Pulmonary Inflammation After Intraperitoneal Administration of Ultrafine Titanium Dioxide (TiO2) At Rest or in Lungs Primed with Lipopolysaccharide

(2010) Changsuk Moon et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Multi-walled carbon nanotubes (Baytubes®): Approach for derivation of occupational exposure limit

(2010) Jürgen Pauluhn   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Acute respiratory and systemic toxicity of pulmonary exposure to rutile Fe-doped TiO2 nanorods

(2010) Abderrahim Nemmar et al.   TOXICOLOGY

Time-course effects of systemically administered diesel exhaust particles in rats

(2010) Abderrahim Nemmar et al.   TOXICOLOGY LETTERS

Air pollution and cardiac remodeling: a role for RhoA/Rho-kinase

(2009) Zhekang Ying et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Functionally important role for arginase 1 in the airway hyperresponsiveness of asthma

(2009) Michelle L. North et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

An evaluation of indoor and outdoor biological particulate matter

(2009) M.Y. Menetrez et al.   ATMOSPHERIC ENVIRONMENT

Ambient Air Pollution Exaggerates Adipose Inflammation and Insulin Resistance in a Mouse Model of Diet-Induced Obesity

(2009) Qinghua Sun et al.   CIRCULATION

Health effects of inhaled engineered and incidental nanoparticles

(2009) Amy K. Madl et al.   CRITICAL REVIEWS IN TOXICOLOGY

Exposure to ambient levels of particles emitted by traffic worsens emphysema in mice

(2009) Fernanda D.T.Q.S. Lopes et al.   ENVIRONMENTAL RESEARCH

Induction of IL-6 and inhibition of IL-8 secretion in the human airway cell line Calu-3 by urban particulate matter collected with a modified method of PM sampling

(2009) Ernesto Alfaro-Moreno et al.   ENVIRONMENTAL RESEARCH

Development of a physiologically based kinetic model for 99m-Technetium-labelled carbon nanoparticles inhaled by humans

(2009) Alexandre R. R. Péry et al.   INHALATION TOXICOLOGY

Diesel exhaust particles modulate the tight junction protein occludin in lung cells in vitro

(2009) Andrea D Lehmann et al.   Particle and Fibre Toxicology

Effects of Chronic Exposure to Air Pollution from Sao Paulo City on Coronary of Swiss Mice, from Birth to Adulthood

(2009) Lícia Mioko Yoshizaki Akinaga et al.   TOXICOLOGIC PATHOLOGY

Diesel Exhaust Particles in the Lung Aggravate Experimental Acute Renal Failure

(2009) Abderrahim Nemmar et al.   TOXICOLOGICAL SCIENCES

Airway Exposure to Silica-Coated TiO2 Nanoparticles Induces Pulmonary Neutrophilia in Mice

(2009) Elina M. Rossi et al.   TOXICOLOGICAL SCIENCES

Pulmonary Nanoparticle Exposure Disrupts Systemic Microvascular Nitric Oxide Signaling

(2009) Timothy R. Nurkiewicz et al.   TOXICOLOGICAL SCIENCES

Pulmonary exposure to diesel exhaust particles promotes cerebral microvessel thrombosis: Protective effect of a cysteine prodrug l-2-oxothiazolidine-4-carboxylic acid

(2009) Abderrahim Nemmar et al.   TOXICOLOGY

Evaluation of the direct systemic and cardiopulmonary effects of diesel particles in spontaneously hypertensive rats

(2009) Abderrahim Nemmar et al.   TOXICOLOGY

Oxidative stress and apoptosis are induced in human endothelial cells exposed to urban particulate matter

(2009) Angélica Montiel-Dávalos et al.   TOXICOLOGY IN VITRO

Differences in cytotoxicity versus pro-inflammatory potency of different PM fractions in human epithelial lung cells

(2009) Maurizio Gualtieri et al.   TOXICOLOGY IN VITRO

Inhalation vs. aspiration of single-walled carbon nanotubes in C57BL/6 mice: inflammation, fibrosis, oxidative stress, and mutagenesis

(2008) A. A. Shvedova et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Particulate matter exposure induces persistent lung inflammation and endothelial dysfunction

(2008) Eiji Tamagawa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Identification of estrogenic and antiestrogenic activities of respirable diesel exhaust particles by bioassay-directed fractionation

(2008) Seung Min Oh et al.   ARCHIVES OF PHARMACAL RESEARCH

Air Pollution Exposure Potentiates Hypertension Through Reactive Oxygen Species-Mediated Activation of Rho/ROCK

(2008) Qinghua Sun et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Isolation and quantitative estimation of diesel exhaust and carbon black particles ingested by lung epithelial cells and alveolar macrophages in vitro

(2008) Rajiv K. Saxena et al.   BIOTECHNIQUES

Air pollution, oxidative damage to DNA, and carcinogenesis

(2008) Peter Møller et al.   CANCER LETTERS

Nanoparticle analysis and characterization methodologies in environmental risk assessment of engineered nanoparticles

(2008) Martin Hassellöv et al.   ECOTOXICOLOGY

Acute Toxicity and Prothrombotic Effects of Quantum Dots: Impact of Surface Charge

(2008) Jorina Geys et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Co-cultures of multiple cell types mimic pulmonary cell communication in response to urban PM10

(2008) E. Alfaro-Moreno et al.   EUROPEAN RESPIRATORY JOURNAL

The Acute Proinflammatory and Prothrombotic Effects of Pulmonary Exposure to Rutile TiO2 Nanorods in Rats

(2008) Abderrahim Nemmar et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

In vitromodels of the human epithelial airway barrier to study the toxic potential of particulate matter

(2008) Barbara Rothen-Rutishauser et al.   Expert Opinion on Drug Metabolism & Toxicology

Ambient Air Particulate Matter Exposure and Tissue Factor Expression in Atherosclerosis

(2008) Qinghua Sun et al.   INHALATION TOXICOLOGY

The Aryl Hydrocarbon Receptor Binds to E2F1 and Inhibits E2F1-induced Apoptosis

(2008) Jennifer L. Marlowe et al.   MOLECULAR BIOLOGY OF THE CELL

Particulate matter inhibits DNA repair and enhances mutagenesis

(2008) Manju Mehta et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Oxidative damage to DNA and repair induced by Norwegian wood smoke particles in human A549 and THP-1 cell lines

(2008) Pernille Høgh Danielsen et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Nanoparticle inhalation augments particle-dependent systemic microvascular dysfunction

(2008) Timothy R Nurkiewicz et al.   Particle and Fibre Toxicology

Induction of apoptosis and absence of inflammation in rat lung after intratracheal instillation of multiwalled carbon nanotubes

(2008) D. Elgrabli et al.   TOXICOLOGY

Nitrophenols isolated from diesel exhaust particles promote the growth of MCF-7 breast adenocarcinoma cells

(2008) Chie Furuta et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Particles from wood smoke and traffic induce differential pro-inflammatory response patterns in co-cultures

(2008) Anette Kocbach et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The ability of oxidative stress to mimic quartz-induced chemokine responses is lung cell line-dependent

(2008) J OVREVIK et al.   TOXICOLOGY LETTERS

Adverse cardiovascular effects of air pollution

(2008) Nicholas L Mills et al.   Nature clinical practice. Cardiovascular medicine