Expert consensus on an in vitro approach to assess pulmonary fibrogenic potential of aerosolized nanomaterials

Nanomaterial Categorization for Assessing Risk Potential To Facilitate Regulatory Decision-Making

(2015) Hilary Godwin et al.   ACS Nano

Repeated exposure to carbon nanotube-based aerosols does not affect the functional properties of a 3D human epithelial airway model

(2015) Savvina Chortarea et al.   Nanotoxicology

MWCNTs of different physicochemical properties cause similar inflammatory responses, but differences in transcriptional and histological markers of fibrosis in mouse lungs

(2015) Sarah S. Poulsen et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Nanotechnology in the real world: Redeveloping the nanomaterial consumer products inventory

(2015) Marina E Vance et al.   Beilstein Journal of Nanotechnology

Engineering an in vitro air-blood barrier by 3D bioprinting

(2015) Lenke Horváth et al.   Scientific Reports

Apoptotic, inflammatory, and fibrogenic effects of two different types of multi-walled carbon nanotubes in mouse lung

(2014) D. van Berlo et al.   ARCHIVES OF TOXICOLOGY

In vivogenotoxicity evaluation of lung cells from Fischer 344 rats following 28 days of inhalation exposure to MWCNTs, plus 28 days and 90 days post-exposure

(2014) Jin Sik Kim et al.   INHALATION TOXICOLOGY

Computational modeling of nanoscale and microscale particle deposition, retention and dosimetry in the mouse respiratory tract

(2014) B. Asgharian et al.   INHALATION TOXICOLOGY

Biological responses according to the shape and size of carbon nanotubes in BEAS-2B and MESO-1 cells

(2014) Hisao Haniu et al.   International Journal of Nanomedicine

Modeling Nanoparticle–Alveolar Epithelial Cell Interactions under Breathing Conditions Using Captive Bubble Surfactometry

(2014) David Schürch et al.   LANGMUIR

A unified framework for nanosafety is needed

(2014) Janeck J. Scott-Fordsmand et al.   Nano Today

Inflammasome activation in airway epithelial cells after multi-walled carbon nanotube exposure mediates a profibrotic response in lung fibroblasts

(2014) Salik Hussain et al.   Particle and Fibre Toxicology

Promotion of lung adenocarcinoma following inhalation exposure to multi-walled carbon nanotubes

(2014) Linda M Sargent et al.   Particle and Fibre Toxicology

Size-dependent cytotoxicity of silver nanoparticles in human lung cells: the role of cellular uptake, agglomeration and Ag release

(2014) Anda R Gliga et al.   Particle and Fibre Toxicology

ITS-NANO - Prioritising nanosafety research to develop a stakeholder driven intelligent testing strategy

(2014) Vicki Stone et al.   Particle and Fibre Toxicology

Atomic Layer Deposition Coating of Carbon Nanotubes with Aluminum Oxide Alters Pro-Fibrogenic Cytokine Expression by Human Mononuclear Phagocytes In Vitro and Reduces Lung Fibrosis in Mice In Vivo

(2014) Alexia J. Taylor et al.   PLoS One

Estimating the effective density of engineered nanomaterials for in vitro dosimetry

(2014) Glen DeLoid et al.   Nature Communications

Mimicking exposures to acute and lifetime concentrations of inhaled silver nanoparticles by two different in vitro approaches

(2014) Fabian Herzog et al.   Beilstein Journal of Nanotechnology

Surface Charge and Cellular Processing of Covalently Functionalized Multiwall Carbon Nanotubes Determine Pulmonary Toxicity

(2013) Ruibin Li et al.   ACS Nano

Mechanisms of carbon nanotube-induced toxicity: Focus on pulmonary inflammation

(2013) Kunal Bhattacharya et al.   ADVANCED DRUG DELIVERY REVIEWS

Breaking theIn VitroAlveolar Type II Cell Proliferation Barrier while Retaining Ion Transport Properties

(2013) Peter F. Bove et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

An improved dispersion method of multi-wall carbon nanotube for inhalation toxicity studies of experimental animals

(2013) Yuhji Taquahashi et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Concern-driven integrated approaches to nanomaterial testing and assessment – report of the NanoSafety Cluster Working Group 10

(2013) Agnes G. Oomen et al.   Nanotoxicology

Towards predicting the lung fibrogenic activity of nanomaterials: experimental validation of an in vitro fibroblast proliferation assay

(2013) Giulia Vietti et al.   Particle and Fibre Toxicology

An improved 3D tetraculture system mimicking the cellular organisation at the alveolar barrier to study the potential toxic effects of particles on the lung

(2013) Sebastian G Klein et al.   Particle and Fibre Toxicology

Exposure of silver-nanoparticles and silver-ions to lung cells in vitro at the air-liquid interface

(2013) Fabian Herzog et al.   Particle and Fibre Toxicology

A triple cell co-culture model of the air–blood barrier reconstructed from primary human cells

(2013) George Jackson et al.   TOXICOLOGY LETTERS

Nanomaterial Toxicity Testing in the 21st Century: Use of a Predictive Toxicological Approach and High-Throughput Screening

(2012) Andre Nel et al.   ACCOUNTS OF CHEMICAL RESEARCH

Hazard identification of inhaled nanomaterials: making use of short-term inhalation studies

(2012) Christoph L. Klein et al.   ARCHIVES OF TOXICOLOGY

Functional Effects of Nanoparticle Exposure on Calu-3 Airway Epithelial Cells

(2012) Amiraj Banga et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Genotoxicity of polyvinylpyrrolidone-coated silver nanoparticles in BEAS 2B cells

(2012) Penny Nymark et al.   TOXICOLOGY

Applying quantitative structure–activity relationship approaches to nanotoxicology: Current status and future potential

(2012) David A. Winkler et al.   TOXICOLOGY

Dispersal State of Multiwalled Carbon Nanotubes Elicits Profibrogenic Cellular Responses That Correlate with Fibrogenesis Biomarkers and Fibrosis in the Murine Lung

(2011) Xiang Wang et al.   ACS Nano

Evaluating the characteristics of multiwall carbon nanotubes

(2011) John H. Lehman et al.   CARBON

A computer model for the simulation of fiber–cell interaction in the alveolar region of the respiratory tract

(2011) R. Sturm   COMPUTERS IN BIOLOGY AND MEDICINE

Informing Selection of Nanomaterial Concentrations for ToxCast in Vitro Testing Based on Occupational Exposure Potential

(2011) Sumit Gangwal et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Polystyrene nanoparticles activate ion transport in human airway epithelial cells

(2011) Joanna McCarthy et al.   International Journal of Nanomedicine

A 3-dimensional in vitro model of epithelioid granulomas induced by high aspect ratio nanomaterials

(2011) Vanesa C Sanchez et al.   Particle and Fibre Toxicology

Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment

(2010) Gerald T. Ankley et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Minimal analytical characterization of engineered nanomaterials needed for hazard assessment in biological matrices

(2010) Hans Bouwmeester et al.   Nanotoxicology

Asbestos, carbon nanotubes and the pleural mesothelium: a review and the hypothesis regarding the role of long fibre retention in the parietal pleura, inflammation and mesothelioma

(2010) Ken Donaldson et al.   Particle and Fibre Toxicology

ISDD: A computational model of particle sedimentation, diffusion and target cell dosimetry for in vitro toxicity studies

(2010) Paul M Hinderliter et al.   Particle and Fibre Toxicology

Reconstituting Organ-Level Lung Functions on a Chip

(2010) D. Huh et al.   SCIENCE

Oxidative stress induction by nanoparticles in THP-1 cells with 4-HNE production: Stress biomarker or oxidative stress signalling molecule?

(2010) L. Foucaud et al.   TOXICOLOGY IN VITRO

A theoretical approach to the deposition and clearance of fibers with variable size in the human respiratory tract

(2009) Robert Sturm et al.   JOURNAL OF HAZARDOUS MATERIALS

A dose-controlled system for air-liquid interface cell exposure and application to zinc oxide nanoparticles

(2009) Anke Lenz et al.   Particle and Fibre Toxicology

Inhalation Toxicity of Multiwall Carbon Nanotubes in Rats Exposed for 3 Months

(2009) Lan Ma-Hock et al.   TOXICOLOGICAL SCIENCES

Co-cultures of multiple cell types mimic pulmonary cell communication in response to urban PM10

(2008) E. Alfaro-Moreno et al.   EUROPEAN RESPIRATORY JOURNAL

In vitromodels of the human epithelial airway barrier to study the toxic potential of particulate matter

(2008) Barbara Rothen-Rutishauser et al.   Expert Opinion on Drug Metabolism & Toxicology

Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study

(2008) Craig A. Poland et al.   Nature Nanotechnology

Non-functionalized multi-walled carbon nanotubes alter the paracellular permeability of human airway epithelial cells

(2008) Bianca Maria Rotoli et al.   TOXICOLOGY LETTERS