Physicochemical characteristics of nanomaterials that affect pulmonary inflammation

The effect of primary particle size on biodistribution of inhaled gold nano-agglomerates

(2013) Suresh K. Balasubramanian et al.   BIOMATERIALS

Nano–bio effects: interaction of nanomaterials with cells

(2013) Liang-Chien Cheng et al.   Nanoscale

Comparative hazard identification of nano- and micro-sized cerium oxide particles based on 28-day inhalation studies in rats

(2013) Ilse Gosens et al.   Nanotoxicology

Comparative inhalation toxicity of multi-wall carbon nanotubes, graphene, graphite nanoplatelets and low surface carbon black

(2013) Lan Ma-Hock et al.   Particle and Fibre Toxicology

An improved 3D tetraculture system mimicking the cellular organisation at the alveolar barrier to study the potential toxic effects of particles on the lung

(2013) Sebastian G Klein et al.   Particle and Fibre Toxicology

The Biologically Effective Dose in Inhalation Nanotoxicology

(2012) Ken Donaldson et al.   ACCOUNTS OF CHEMICAL RESEARCH

Comprehensive Analysis of the Effects of CdSe Quantum Dot Size, Surface Charge, and Functionalization on Primary Human Lung Cells

(2012) Amber Nagy et al.   ACS Nano

Neutrophils in acute lung injury

(2012) Xiao et al.   Frontiers in Bioscience-Landmark

Comparison of acute oxidative stress on rat lung induced by nano and fine-scale, soluble and insoluble metal oxide particles: NiO and TiO2

(2012) Masanori Horie et al.   INHALATION TOXICOLOGY

Change in agglomeration status and toxicokinetic fate of various nanoparticlesin vivofollowing lung exposure in rats

(2012) Otto Creutzenberg et al.   INHALATION TOXICOLOGY

Nanoparticles: a review of particle toxicology following inhalation exposure

(2012) Shahnaz Bakand et al.   INHALATION TOXICOLOGY

Type 1 pulmonary epithelial cells: a new compartment involved in the slow phase of particle clearance from alveoli

(2012) Robert L. Maynard et al.   Nanotoxicology

Acute pulmonary dose–responses to inhaled multi-walled carbon nanotubes

(2012) Dale W. Porter et al.   Nanotoxicology

Use of silver nanowires to determine thresholds for fibre length-dependent pulmonary inflammation and inhibition of macrophage migration in vitro

(2012) Anja Schinwald et al.   Particle and Fibre Toxicology

The Threshold Length for Fiber-Induced Acute Pleural Inflammation: Shedding Light on the Early Events in Asbestos-Induced Mesothelioma

(2012) Anja Schinwald et al.   TOXICOLOGICAL SCIENCES

Differential Mouse Pulmonary Dose and Time Course Responses to Titanium Dioxide Nanospheres and Nanobelts

(2012) Dale W. Porter et al.   TOXICOLOGICAL SCIENCES

Tissue Distribution of Inhaled Micro- and Nano-sized Cerium Oxide Particles in Rats: Results From a 28-Day Exposure Study

(2012) Liesbeth Geraets et al.   TOXICOLOGICAL SCIENCES

Zeta Potential and Solubility to Toxic Ions as Mechanisms of Lung Inflammation Caused by Metal/Metal Oxide Nanoparticles

(2012) Wan-Seob Cho et al.   TOXICOLOGICAL SCIENCES

Cytokine production by co-cultures exposed to monodisperse amorphous silica nanoparticles: The role of size and surface area

(2012) Dorota Napierska et al.   TOXICOLOGY LETTERS

Effects of inhaled nano-TiO2 aerosols showing two distinct agglomeration states on rat lungs

(2012) A. Noël et al.   TOXICOLOGY LETTERS

Graphene-Based Nanoplatelets: A New Risk to the Respiratory System as a Consequence of Their Unusual Aerodynamic Properties

(2011) Anja Schinwald et al.   ACS Nano

Toxicology of nanoparticles

(2011) Andreas Elsaesser et al.   ADVANCED DRUG DELIVERY REVIEWS

Length-Dependent Retention of Carbon Nanotubes in the Pleural Space of Mice Initiates Sustained Inflammation and Progressive Fibrosis on the Parietal Pleura

(2011) Fiona A. Murphy et al.   AMERICAN JOURNAL OF PATHOLOGY

The effect of particle size on the cytotoxicity, inflammation, developmental toxicity and genotoxicity of silver nanoparticles

(2011) Margriet V.D.Z. Park et al.   BIOMATERIALS

Biological Interactions of Graphene-Family Nanomaterials: An Interdisciplinary Review

(2011) Vanesa C. Sanchez et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Size-Controlled Dissolution of Organic-Coated Silver Nanoparticles

(2011) Rui Ma et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Pulmonary toxicity of inhaled nanoscale and fine zinc oxide particles: Mass and surface area as an exposure metric

(2011) Meng Ho et al.   INHALATION TOXICOLOGY

Influence of particle size on regional lung deposition – What evidence is there?

(2011) Thiago C. Carvalho et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Toxicological Evaluation of Lung Responses After Intratracheal Exposure to Non-Dispersed Titanium Dioxide Nanorods

(2011) Jenny R. Roberts et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Cellular uptake mechanisms and toxicity of quantum dots in dendritic cells

(2011) Leshuai W Zhang et al.   Nanomedicine

Differential pro-inflammatory effects of metal oxide nanoparticles and their soluble ionsin vitroandin vivo; zinc and copper nanoparticles, but not their ions, recruit eosinophils to the lungs

(2011) Wan-Seob Cho et al.   Nanotoxicology

Risks from accidental exposures to engineered nanoparticles and neurological health effects: A critical review

(2011) Myrtill Simkó et al.   Particle and Fibre Toxicology

Shape matters: effects of silver nanospheres and wires on human alveolar epithelial cells

(2011) Linda C Stoehr et al.   Particle and Fibre Toxicology

Progressive severe lung injury by zinc oxide nanoparticles; the role of Zn2+ dissolution inside lysosomes

(2011) Wan-Seob Cho et al.   Particle and Fibre Toxicology

Effects of various physicochemical characteristics on the toxicities of ZnO and TiO2 nanoparticles toward human lung epithelial cells

(2011) I-Lun Hsiao et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Potential of coculture in vitro models to study inflammatory and sensitizing effects of particles on the lung

(2011) Sebastian G. Klein et al.   TOXICOLOGY IN VITRO

Surface-Charge-Dependent Cell Localization and Cytotoxicity of Cerium Oxide Nanoparticles

(2010) Atul Asati et al.   ACS Nano

Testing Metal-Oxide Nanomaterials for Human Safety

(2010) Robert Landsiedel et al.   ADVANCED MATERIALS

Particulate Matter Air Pollution and Cardiovascular Disease

(2010) Robert D. Brook et al.   CIRCULATION

Time-response relationship of nano and micro particle induced lung inflammation. Quartz as reference compound

(2010) Martin Roursgaard et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Update on Macrophage Clearance of Inhaled Micro- and Nanoparticles

(2010) Marianne Geiser   Journal of Aerosol Medicine and Pulmonary Drug Delivery

Acute Toxicity of Ferric Oxide and Zinc Oxide Nanoparticles in Rats

(2010) Lijuan Wang et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Nano-silver – feasibility and challenges for human health risk assessment based on open literature

(2010) Frans M. Christensen et al.   Nanotoxicology

Possible genotoxic mechanisms of nanoparticles: Criteria for improved test strategies

(2010) Ken Donaldson et al.   Nanotoxicology

Rapid translocation of nanoparticles from the lung airspaces to the body

(2010) Hak Soo Choi et al.   NATURE BIOTECHNOLOGY

Asbestos, carbon nanotubes and the pleural mesothelium: a review and the hypothesis regarding the role of long fibre retention in the parietal pleura, inflammation and mesothelioma

(2010) Ken Donaldson et al.   Particle and Fibre Toxicology

Impact of agglomeration state of nano- and submicron sized gold particles on pulmonary inflammation

(2010) Ilse Gosens et al.   Particle and Fibre Toxicology

Distribution and persistence of pleural penetrations by multi-walled carbon nanotubes

(2010) Robert R Mercer et al.   Particle and Fibre Toxicology

Deposition and biokinetics of inhaled nanoparticles

(2010) Marianne Geiser et al.   Particle and Fibre Toxicology

Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1  and IL-1 

(2010) A. S. Yazdi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reconstituting Organ-Level Lung Functions on a Chip

(2010) D. Huh et al.   SCIENCE

Poorly soluble particulates: Searching for a unifying denominator of nanoparticles and fine particles for DNEL estimation

(2010) Jürgen Pauluhn   TOXICOLOGY

Cargo surface hydrophobicity is sufficient to overcome the nuclear pore complex selectivity barrier

(2009) Bracha Naim et al.   EMBO JOURNAL

Role of oxidative damage in toxicity of particulates

(2009) Peter Møller et al.   FREE RADICAL RESEARCH

Changing the dose metric for inhalation toxicity studies: Short-term study in rats with engineered aerosolized amorphous silica nanoparticles

(2009) Christie M. Sayes et al.   INHALATION TOXICOLOGY

Particle deposition in human respiratory system: Deposition of concentrated hygroscopic aerosols

(2009) Suresh K. Varghese et al.   INHALATION TOXICOLOGY

Understanding biophysicochemical interactions at the nano–bio interface

(2009) Andre E. Nel et al.   NATURE MATERIALS

Pulmonary Toxicity and Fate of Agglomerated 10 and 40 nm Aluminum Oxyhydroxides following 4-Week Inhalation Exposure of Rats: Toxic Effects are Determined by Agglomerated, not Primary Particle Size

(2009) Jürgen Pauluhn   TOXICOLOGICAL SCIENCES

Subchronic 13-Week Inhalation Exposure of Rats to Multiwalled Carbon Nanotubes: Toxic Effects Are Determined by Density of Agglomerate Structures, Not Fibrillar Structures

(2009) Jürgen Pauluhn   TOXICOLOGICAL SCIENCES

Inhalation Toxicity of Multiwall Carbon Nanotubes in Rats Exposed for 3 Months

(2009) Lan Ma-Hock et al.   TOXICOLOGICAL SCIENCES

Retrospective analysis of 4-week inhalation studies in rats with focus on fate and pulmonary toxicity of two nanosized aluminum oxyhydroxides (boehmite) and pigment-grade iron oxide (magnetite): The key metric of dose is particle mass and not particle surface area

(2009) Jürgen Pauluhn   TOXICOLOGY

Comparative pulmonary toxicity study of nano-TiO2 particles of different sizes and agglomerations in rats: Different short- and long-term post-instillation results

(2009) Norihiro Kobayashi et al.   TOXICOLOGY

Oxidative stress and proinflammatory effects of carbon black and titanium dioxide nanoparticles: Role of particle surface area and internalized amount

(2009) Salik Hussain et al.   TOXICOLOGY

Mouse pulmonary dose- and time course-responses induced by exposure to multi-walled carbon nanotubes

(2009) Dale W. Porter et al.   TOXICOLOGY

Interactions of nanoparticles with pulmonary structures and cellular responses

(2008) Christian Mühlfeld et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The role of oxidative stress in ambient particulate matter-induced lung diseases and its implications in the toxicity of engineered nanoparticles

(2008) Ning Li et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inhaled nanoparticles—A current review

(2008) Wei Yang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Genotoxicity investigations on nanomaterials: Methods, preparation and characterization of test material, potential artifacts and limitations—Many questions, some answers

(2008) Robert Landsiedel et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY

Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study

(2008) Craig A. Poland et al.   Nature Nanotechnology

Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts

(2008) M. Lundqvist et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Subchronic Inhalation Toxicity of Silver Nanoparticles

(2008) Jae Hyuck Sung et al.   TOXICOLOGICAL SCIENCES

Comparative study of pulmonary responses to nano- and submicron-sized ferric oxide in rats

(2008) Mo-Tao Zhu et al.   TOXICOLOGY

In vitro investigation of oxide nanoparticle and carbon nanotube toxicity and intracellular accumulation in A549 human pneumocytes

(2008) A. Simon-Deckers et al.   TOXICOLOGY

Oxidative stress and apoptosis induced by titanium dioxide nanoparticles in cultured BEAS-2B cells

(2008) Eun-Jung Park et al.   TOXICOLOGY LETTERS

Comparing fate and effects of three particles of different surface properties: Nano-TiO2, pigmentary TiO2 and quartz

(2008) Ben van Ravenzwaay et al.   TOXICOLOGY LETTERS

The Role of Macrophages in the Clearance of Inhaled Ultrafine Titanium Dioxide Particles

(2007) Marianne Geiser et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY