Regulation of Mitophagy by Sirtuin Family Proteins: A Vital Role in Aging and Age-Related Diseases

SIRT1 and SIRT2 Activity Control in Neurodegenerative Diseases

(2021) Ramu Manjula et al.   Frontiers in Pharmacology

17β-Estradiol Induces Mitophagy Upregulation to Protect Chondrocytes via the SIRT1-Mediated AMPK/mTOR Signaling Pathway

(2021) Runhong Mei et al.   Frontiers in Endocrinology

Rutin and Gallic Acid Regulates Mitochondrial Functions via the SIRT1 Pathway in C2C12 Myotubes

(2021) Wei-Tang Chang et al.   Antioxidants

Quercetin Improves Cardiomyocyte Vulnerability to Hypoxia by Regulating SIRT1/TMBIM6-Related Mitophagy and Endoplasmic Reticulum Stress

(2021) Xing Chang et al.   Oxidative Medicine and Cellular Longevity

Mechanistic insights into AMPK-SIRT3 positive feedback loop-mediated chondrocyte mitochondrial quality control in osteoarthritis pathogenesis

(2021) Yang Chen et al.   PHARMACOLOGICAL RESEARCH

MiR-22 Inhibition Alleviates Cardiac Dysfunction in Doxorubicin-Induced Cardiomyopathy by Targeting the sirt1/PGC-1α Pathway

(2021) Runze Wang et al.   Frontiers in Physiology

Sirt3-mediated mitophagy regulates AGEs-induced BMSCs senescence and senile osteoporosis

(2021) Yuanyuan Guo et al.   Redox Biology

Bhlhe40/Sirt1 Axis-Regulated Mitophagy Is Implicated in All-Trans Retinoic Acid-Induced Spina Bifida Aperta

(2021) Lu Zhao et al.   Frontiers in Cell and Developmental Biology

Cardiac senescence is alleviated by the natural flavone acacetin via enhancing mitophagy

(2021) Yi-Xiang Hong et al.   Aging-US

Honokiol improves cognitive impairment in APP/PS1 mice through activating mitophagy and mitochondrial unfolded protein response

(2021) Mingyue Hou et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Lycopene mitigates DEHP-induced hepatic mitochondrial quality control disorder via regulating SIRT1/PINK1/mitophagy axis and mitochondrial unfolded protein response

(2021) Yi Zhao et al.   ENVIRONMENTAL POLLUTION

Mitophagy in Huntington's disease

(2021) I. Šonský et al.   NEUROCHEMISTRY INTERNATIONAL

Mitophagy: Molecular Mechanisms, New Concepts on Parkin Activation and the Emerging Role of AMPK/ULK1 Axis

(2021) Roberto Iorio et al.   Cells

Mutant HTT (huntingtin) impairs mitophagy in a cellular model of Huntington disease

(2020) Sandra Franco-Iborra et al.   Autophagy

Mitochondria-to-nucleus retrograde signaling drives formation of cytoplasmic chromatin and inflammation in senescence

(2020) Maria Grazia Vizioli et al.   GENES & DEVELOPMENT

PINK1/Parkin Mediated Mitophagy, Ca2+ Signalling, and ER–Mitochondria Contacts in Parkinson’s Disease

(2020) Lucia Barazzuol et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Role of Parkin-mediated mitophagy in the protective effect of polydatin in sepsis-induced acute kidney injury

(2020) Youguang Gao et al.   Journal of Translational Medicine

Defective mitochondria ignite the SASP

(2020) Eytan Zlotorynski   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Luteolin Attenuates Doxorubicin-Induced Cardiotoxicity Through Promoting Mitochondrial Autophagy

(2020) Haixia Xu et al.   Frontiers in Physiology

Melatonin ameliorates excessive PINK1/Parkin-mediated mitophagy by enhancing SIRT1 expression in granulosa cells of PCOS

(2020) Shanling Yi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

SIRT3 deficiency is resistant to autophagy‐dependent ferroptosis by inhibiting the AMPK/mTOR pathway and promoting GPX4 levels

(2020) Dandan Han et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Melatonin Attenuates Anoxia/Reoxygenation Injury by Inhibiting Excessive Mitophagy Through the MT2/SIRT3/FoxO3a Signaling Pathway in H9c2 Cells

(2020) Jinjing Wu et al.   Drug Design Development and Therapy

Aging alters acetylation status in skeletal and cardiac muscles

(2020) Dongwook Yeo et al.   GeroScience

SIRT1 alleviates high-magnitude compression-induced senescence in nucleus pulposus cells via PINK1-dependent mitophagy

(2020) Yiyang Wang et al.   Aging-US

Critical role of mitochondrial ubiquitination and the OPTN–ATG9A axis in mitophagy

(2020) Koji Yamano et al.   JOURNAL OF CELL BIOLOGY

SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer

(2020) Shijia Bi et al.   Protein & Cell

Allicin Regulates Energy Homeostasis through Brown Adipose Tissue

(2020) Chuanhai Zhang et al.   iScience

Melatonin attenuates diabetic cardiomyopathy and reduces myocardial vulnerability to ischemia‐reperfusion injury by improving mitochondrial quality control: Role of SIRT6

(2020) Li‐Ming Yu et al.   JOURNAL OF PINEAL RESEARCH

Quercetin alleviates kidney fibrosis by reducing renal tubular epithelial cell senescence through the SIRT1/PINK1/mitophagy axis

(2020) Tao Liu et al.   LIFE SCIENCES

Epigallocatechin Gallate Effectively Affects Senescence and Anti-SASP via SIRT3 in 3T3-L1 Preadipocytes in Comparison with Other Bioactive Substances

(2020) Stephanie Lilja et al.   Oxidative Medicine and Cellular Longevity

Physical exercise may exert its therapeutic influence on Alzheimer's disease through the reversal of mitochondrial dysfunction via SIRT1-FOXO1/3-PINK1-Parkin–mediated mitophagy

(2020) Na Zhao et al.   Journal of Sport and Health Science

Mfn2 Overexpression Attenuates Cardio-Cerebrovascular Ischemia–Reperfusion Injury Through Mitochondrial Fusion and Activation of the AMPK/Sirt3 Signaling

(2020) Min Liu et al.   Frontiers in Cell and Developmental Biology

Irisin Mitigates Oxidative Stress, Chondrocyte Dysfunction and Osteoarthritis Development through Regulating Mitochondrial Integrity and Autophagy

(2020) Feng-Sheng Wang et al.   Antioxidants

Mitochondrial SIRT3 confers neuroprotection in Huntington's disease by regulation of oxidative challenges and mitochondrial dynamics

(2020) Luana Naia et al.   FREE RADICAL BIOLOGY AND MEDICINE

Biological Functions of Autophagy Genes: A Disease Perspective

(2019) Beth Levine et al.   CELL

Resistance Exercise Improves Mitochondrial Quality Control in a Rat Model of Sporadic Inclusion Body Myositis

(2019) Jung-Hoon Koo et al.   GERONTOLOGY

Modulation of miR-34a/SIRT1 signaling protects cochlear hair cells against oxidative stress and delays age-related hearing loss through coordinated regulation of mitophagy and mitochondrial biogenesis

(2019) Hao Xiong et al.   NEUROBIOLOGY OF AGING

Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease

(2019) Evandro F. Fang et al.   NATURE NEUROSCIENCE

Spatiotemporal Control of ULK1 Activation by NDP52 and TBK1 during Selective Autophagy

(2019) Jose Norberto S. Vargas et al.   MOLECULAR CELL

Caloric Restriction Mimetics against Age-Associated Disease: Targets, Mechanisms, and Therapeutic Potential

(2019) Frank Madeo et al.   Cell Metabolism

Mitophagy and NAD+ inhibit Alzheimer disease

(2019) Evandro F. Fang   Autophagy

Sirt3 regulates mitophagy level to promote diabetic corneal epithelial wound healing

(2019) Jianzhang Hu et al.   EXPERIMENTAL EYE RESEARCH

Mitochonic acid‐5 attenuates TNF‐α‐mediated neuronal inflammation via activating Parkin‐related mitophagy and augmenting the AMPK–Sirt3 pathways

(2019) Dezhi Huang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Regulation of UCP1 and Mitochondrial Metabolism in Brown Adipose Tissue by Reversible Succinylation

(2019) GuoXiao Wang et al.   MOLECULAR CELL

Mitophagy in Cancer: A Tale of Adaptation

(2019) Vara-Perez et al.   Cells

Loss of Rubicon ameliorates doxorubicin-induced cardiotoxicity through enhancement of mitochondrial quality

(2019) Xiaoyun Liu et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

PGRN acts as a novel regulator of mitochondrial homeostasis by facilitating mitophagy and mitochondrial biogenesis to prevent podocyte injury in diabetic nephropathy

(2019) Di Zhou et al.   Cell Death & Disease

SESN2 protects against doxorubicin-induced cardiomyopathy via rescuing mitophagy and improving mitochondrial function

(2019) Panxia Wang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The genetic architecture of Parkinson's disease

(2019) Cornelis Blauwendraat et al.   LANCET NEUROLOGY

Fragmented mitochondria released from microglia trigger A1 astrocytic response and propagate inflammatory neurodegeneration

(2019) Amit U. Joshi et al.   NATURE NEUROSCIENCE

Ageing as a risk factor for neurodegenerative disease

(2019) Yujun Hou et al.   Nature Reviews Neurology

Cellular Senescence: Defining a Path Forward

(2019) Vassilis Gorgoulis et al.   CELL

CircERCC2 ameliorated intervertebral disc degeneration by regulating mitophagy and apoptosis through miR-182-5p/SIRT1 axis

(2019) Lin Xie et al.   Cell Death & Disease

SIRT1/PGC-1 pathway activation triggers autophagy/mitophagy and attenuates oxidative damage in intestinal epithelial cells

(2019) Danyang Liang et al.   BIOCHIMIE

2, 2′, 4, 4′-tetrabromodiphenyl ether (BDE-47) induces mitochondrial dysfunction and related liver injury via eliciting miR-34a-5p-mediated mitophagy impairment

(2019) Feng Chen et al.   ENVIRONMENTAL POLLUTION

The Role and Mechanism of SIRT1 in Resveratrol-regulated Osteoblast Autophagy in Osteoporosis Rats

(2019) Xuhao Yang et al.   Scientific Reports

Loss of sirtuin 1 and mitofusin 2 contributes to enhanced ischemia/reperfusion injury in aged livers

(2018) Sung Kook Chun et al.   AGING CELL

Mst1 inhibits Sirt3 expression and contributes to diabetic cardiomyopathy through inhibiting Parkin-dependent mitophagy

(2018) Shanjie Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis

(2018) Paul K. Ziegler et al.   CELL

SIRT3 Facilitates Amniotic Fluid Stem Cells to Repair Diabetic Nephropathy Through Protecting Mitochondrial Homeostasis by Modulation of Mitophagy

(2018) Jianxun Feng et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

SIRT3 deficiency exacerbates p53/Parkin‑mediated mitophagy inhibition and promotes mitochondrial dysfunction: Implication for aged hearts

(2018) Yan Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Autophagy and mitophagy in ALS

(2018) Chantell S. Evans et al.   NEUROBIOLOGY OF DISEASE

Short-Duration Swimming Exercise after Myocardial Infarction Attenuates Cardiac Dysfunction and Regulates Mitochondrial Quality Control in Aged Mice

(2018) Dajun Zhao et al.   Oxidative Medicine and Cellular Longevity

Doxorubicin-induced mitophagy and mitochondrial damage is associated with dysregulation of the PINK1/parkin pathway

(2018) Jian Yin et al.   TOXICOLOGY IN VITRO

A novel small-molecule activator of Sirtuin-1 induces autophagic cell death/mitophagy as a potential therapeutic strategy in glioblastoma

(2018) Zhi-qiang Yao et al.   Cell Death & Disease

SIRT3 Protects Rotenone-induced Injury in SH-SY5Y Cells by Promoting Autophagy through the LKB1-AMPK-mTOR Pathway

(2018) Meng Zhang et al.   Aging and Disease

Therapeutic effect of Sirtuin 3 on ameliorating nonalcoholic fatty liver disease: The role of the ERK-CREB pathway and Bnip3-mediated mitophagy

(2018) Ruibing Li et al.   Redox Biology

Correction: SIRT4 interacts with OPA1 and regulates mitochondrial quality control and mitophagy

(2018) Alexander Lang et al.   Aging-US

Melatonin Ameliorates the Progression of Atherosclerosis via Mitophagy Activation and NLRP3 Inflammasome Inhibition

(2018) Sai Ma et al.   Oxidative Medicine and Cellular Longevity

Arginine methylation of SIRT7 couples glucose sensing with mitochondria biogenesis

(2018) Wei‐Wei Yan et al.   EMBO REPORTS

SIRT3 a Major Player in Attenuation of Hepatic Ischemia-Reperfusion Injury by Reducing ROS via Its Downstream Mediators: SOD2, CYP-D, and HIF-1α

(2018) Gaurav Katwal et al.   Oxidative Medicine and Cellular Longevity

RAB7A phosphorylation by TBK1 promotes mitophagy via the PINK-PARKIN pathway

(2018) J.-M. Heo et al.   Science Advances

Mitophagy and Alzheimer’s Disease: Cellular and Molecular Mechanisms

(2017) Jesse S. Kerr et al.   TRENDS IN NEUROSCIENCES

Sirtuin 3 Deficiency Accelerates Hypertensive Cardiac Remodeling by Impairing Angiogenesis

(2017) Tong Wei et al.   Journal of the American Heart Association

Structural Basis of Sirtuin 6 Activation by Synthetic Small Molecules

(2016) Weijie You et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mitochondrial Sirtuin Network Reveals Dynamic SIRT3-Dependent Deacetylation in Response to Membrane Depolarization

(2016) Wen Yang et al.   CELL

NAD + Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair

(2016) Evandro Fei Fang et al.   Cell Metabolism

Mitochondrial Dysfunction Induces Senescence with a Distinct Secretory Phenotype

(2016) Christopher D. Wiley et al.   Cell Metabolism

Mitochondria are required for pro‐ageing features of the senescent phenotype

(2016) Clara Correia‐Melo et al.   EMBO JOURNAL

BNIP3 Protein Suppresses PINK1 Kinase Proteolytic Cleavage to Promote Mitophagy

(2016) Tongmei Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Atg8 family LC3/GABARAP proteins are crucial for autophagosome–lysosome fusion but not autophagosome formation during PINK1/Parkin mitophagy and starvation

(2016) Thanh Ngoc Nguyen et al.   JOURNAL OF CELL BIOLOGY

Mechanisms of Selective Autophagy

(2016) Gabriele Zaffagnini et al.   JOURNAL OF MOLECULAR BIOLOGY

Mitochondrial Metabolism Power SIRT2-Dependent Deficient Traffic Causing Alzheimer’s-Disease Related Pathology

(2016) D. F. Silva et al.   MOLECULAR NEUROBIOLOGY

Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds

(2016) Michael S. Bonkowski et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Autophagy: controlling cell fate in rheumatic diseases

(2016) Jason S. Rockel et al.   Nature Reviews Rheumatology

Deciphering the Molecular Signals of PINK1/Parkin Mitophagy

(2016) Thanh N. Nguyen et al.   TRENDS IN CELL BIOLOGY

Loss of Sirt1 Promotes Prostatic Intraepithelial Neoplasia, Reduces Mitophagy, and Delays Park2 Translocation to Mitochondria

(2015) Gabriele Di Sante et al.   AMERICAN JOURNAL OF PATHOLOGY

SIRT5 regulation of ammonia-induced autophagy and mitophagy

(2015) Lucia Polletta et al.   Autophagy

SIRT3-SOD2-mROS-dependent autophagy in cadmium-induced hepatotoxicity and salvage by melatonin

(2015) Huifeng Pi et al.   Autophagy

AK-1, a specific SIRT2 inhibitor, induces cell cycle arrest by downregulating Snail in HCT116 human colon carcinoma cells

(2015) Min Gyeong Cheon et al.   CANCER LETTERS

Sirtuin 1 suppresses mitochondrial dysfunction of ischemic mouse livers in a mitofusin 2-dependent manner

(2015) T G Biel et al.   CELL DEATH AND DIFFERENTIATION

The mitochondrial protein BNIP3L is the substrate of PARK2 and mediates mitophagy in PINK1/PARK2 pathway

(2015) Feng Gao et al.   HUMAN MOLECULAR GENETICS

mTOR: a pharmacologic target for autophagy regulation

(2015) Young Chul Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Deacetylation of Nuclear LC3 Drives Autophagy Initiation under Starvation

(2015) Rui Huang et al.   MOLECULAR CELL

Coordination of mitophagy and mitochondrial biogenesis during ageing in C. elegans

(2015) Konstantinos Palikaras et al.   NATURE

Acetylation of Beclin 1 inhibits autophagosome maturation and promotes tumour growth

(2015) Ting Sun et al.   Nature Communications

The Sirtuin-2 Inhibitor AK7 Is Neuroprotective in Models of Parkinson’s Disease but Not Amyotrophic Lateral Sclerosis and Cerebral Ischemia

(2015) Xiqun Chen et al.   PLoS One

SRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass

(2014) Evi M. Mercken et al.   AGING CELL

Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila

(2014) Anne Simonsen et al.   Autophagy

Longevity pathways converge on autophagy genes to regulate life span inCaenorhabditis elegans

(2014) Márton L. Tóth et al.   Autophagy

Contribution of defective mitophagy to the neurodegeneration in DNA repair-deficient disorders

(2014) Morten Scheibye-Knudsen et al.   Autophagy

Defective Mitophagy in XPA via PARP-1 Hyperactivation and NAD+/SIRT1 Reduction

(2014) Evandro Fei Fang et al.   CELL

The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy

(2014) Baris Bingol et al.   NATURE

Antiaging Properties of a Grape-Derived Antioxidant Are Regulated by Mitochondrial Balance of Fusion and Fission Leading to Mitophagy Triggered by a Signaling Network of Sirt1-Sirt3-Foxo3-PINK1-PARKIN

(2014) Somak Das et al.   Oxidative Medicine and Cellular Longevity

SIRT1 and other sirtuins in metabolism

(2014) Hung-Chun Chang et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Regulation of MnSOD Enzymatic Activity by Sirt3 Connects the Mitochondrial Acetylome Signaling Networks to Aging and Carcinogenesis

(2013) Randa Tao et al.   ANTIOXIDANTS & REDOX SIGNALING

MicroRNA-22 Regulates Cardiac Hypertrophy and Remodeling in Response to Stress

(2013) Zhan-Peng Huang et al.   CIRCULATION RESEARCH

SIRT3 deacetylates FOXO3 to protect mitochondria against oxidative damage

(2013) Anne H.H. Tseng et al.   FREE RADICAL BIOLOGY AND MEDICINE

mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6

(2013) Francesca Nazio et al.   NATURE CELL BIOLOGY

Ex-527 inhibits Sirtuins by exploiting their unique NAD+-dependent deacetylation mechanism

(2013) M. Gertz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial dysfunction and oxidative stress in Parkinson's disease

(2013) Sudhakar Raja Subramaniam et al.   PROGRESS IN NEUROBIOLOGY

PINK1-Phosphorylated Mitofusin 2 Is a Parkin Receptor for Culling Damaged Mitochondria

(2013) Y. Chen et al.   SCIENCE

The pathways of mitophagy for quality control and clearance of mitochondria

(2012) G Ashrafi et al.   CELL DEATH AND DIFFERENTIATION

SIRT1 Is Required for AMPK Activation and the Beneficial Effects of Resveratrol on Mitochondrial Function

(2012) Nathan L. Price et al.   Cell Metabolism

Mitochondrial quality control: a matter of life and death for neurons

(2012) Elena I Rugarli et al.   EMBO JOURNAL

Central Role of Mitofusin 2 in Autophagosome-Lysosome Fusion in Cardiomyocytes

(2012) Ting Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calorie restriction and prevention of age-associated chronic disease

(2011) Daniela Omodei et al.   FEBS LETTERS

Inhibition of autophagy in the heart induces age-related cardiomyopathy

(2010) Manabu Taneike et al.   Autophagy

Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes

(2010) Nirmala Hariharan et al.   CIRCULATION RESEARCH

FoxOs Inhibit mTORC1 and Activate Akt by Inducing the Expression of Sestrin3 and Rictor

(2010) Chia-Chen Chen et al.   DEVELOPMENTAL CELL

Autophagy basics

(2010) Isei Tanida   MICROBIOLOGY AND IMMUNOLOGY

Feedback between p21 and reactive oxygen production is necessary for cell senescence

(2010) João F Passos et al.   Molecular Systems Biology

Erratum: Lessons on longevity from budding yeast

(2010) Matt Kaeberlein   NATURE

THE JOURNAL OF NUTRITION: RETARDED GROWTH, LIFE SPAN, ULTIMATE BODY SIZE AND AGE CHANGES IN THE ALBINO RAT AFTER FEEDING DIETS RESTRICTED IN CALORIES

(2010) C. M. McCay et al.   NUTRITION REVIEWS

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

(2010) Derek P. Narendra et al.   PLOS BIOLOGY

Autophagy and amino acid homeostasis are required for chronological longevity inSaccharomyces cerevisiae

(2009) Ashley L. Alvers et al.   AGING CELL

SIRT2-mediated protein deacetylation: An emerging key regulator in brain physiology and pathology

(2009) Kai Harting et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Mitochondrial Dysfunction Contributes to Oncogene-Induced Senescence

(2009) O. Moiseeva et al.   MOLECULAR AND CELLULAR BIOLOGY

Prohibitin couples diapause signalling to mitochondrial metabolism during ageing in C. elegans

(2009) Marta Artal-Sanz et al.   NATURE

Caloric restriction, SIRT1 and longevity

(2009) Carles Cantó et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

(2008) I. H. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis

(2008) B.-H. Ahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor

(2008) Jean-Philippe Coppé et al.   PLOS BIOLOGY