SRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass
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Title
SRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass
Authors
Keywords
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Journal
AGING CELL
Volume 13, Issue 5, Pages 787-796
Publisher
Wiley
Online
2014-06-17
DOI
10.1111/acel.12220
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Note: Only part of the references are listed.- Muscle Mitohormesis Promotes Longevity via Systemic Repression of Insulin Signaling
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- (2013) Alejandro Martin-Montalvo et al. Nature Communications
- Cardiovascular Effects of a Novel SIRT1 Activator, SRT2104, in Otherwise Healthy Cigarette Smokers
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- (2012) Ethan Hoffmann et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
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- (2012) Melda Onal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Silent information regulator (Sir)T1 inhibits NF-κB signaling to maintain normal skeletal remodeling
- (2012) James R Edwards et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Are sirtuins viable targets for improving healthspan and lifespan?
- (2012) Joseph A. Baur et al. NATURE REVIEWS DRUG DISCOVERY
- A Pilot Randomized, Placebo Controlled, Double Blind Phase I Trial of the Novel SIRT1 Activator SRT2104 in Elderly Volunteers
- (2012) Vincenzo Libri et al. PLoS One
- Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans
- (2011) Silvie Timmers et al. Cell Metabolism
- SirT1 Regulates Adipose Tissue Inflammation
- (2011) M. P. Gillum et al. DIABETES
- Sirt1 Is a Regulator of Bone Mass and a Repressor ofSostEncoding for Sclerostin, a Bone Formation Inhibitor
- (2011) Einav Cohen-Kfir et al. ENDOCRINOLOGY
- Hepatic overexpression of SIRT1 in mice attenuates endoplasmic reticulum stress and insulin resistance in the liver
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- (2011) H-O Jin et al. ONCOGENE
- SRT1720 improves survival and healthspan of obese mice
- (2011) Robin K. Minor et al. Scientific Reports
- Caloric restriction attenuates the age-associated increase of adipose-derived stem cells but further reduces their proliferative capacity
- (2010) Eric G. Schmuck et al. AGE
- Decreased oxidative stress and greater bone anabolism in the aged, when compared to the young, murine skeleton with parathyroid hormone administration
- (2010) Robert L. Jilka et al. AGING CELL
- SRT1720, SRT2183, SRT1460, and Resveratrol Are Not Direct Activators of SIRT1
- (2010) Michelle Pacholec et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice
- (2010) Richard A. Miller et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- The Estrogen Receptor-α in Osteoclasts Mediates the Protective Effects of Estrogens on Cancellous But Not Cortical Bone
- (2010) Marta Martin-Millan et al. MOLECULAR ENDOCRINOLOGY
- Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer
- (2010) Daniel Herranz et al. Nature Communications
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- Transcript profiling and lipidomic analysis of ceramide subspecies in mouse embryonic stem cells and embryoid bodies
- (2009) Hyejung Park et al. JOURNAL OF LIPID RESEARCH
- Muscle CD31(−) CD45(−) Side Population Cells Promote Muscle Regeneration by Stimulating Proliferation and Migration of Myoblasts
- (2008) Norio Motohashi et al. AMERICAN JOURNAL OF PATHOLOGY
- The NAD+-Dependent Deacetylase SIRT1 Modulates CLOCK-Mediated Chromatin Remodeling and Circadian Control
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- Shared Principles in NF-κB Signaling
- (2008) Matthew S. Hayden et al. CELL
- Resveratrol Delays Age-Related Deterioration and Mimics Transcriptional Aspects of Dietary Restriction without Extending Life Span
- (2008) Kevin J. Pearson et al. Cell Metabolism
- A Low Dose of Dietary Resveratrol Partially Mimics Caloric Restriction and Retards Aging Parameters in Mice
- (2008) Jamie L. Barger et al. PLoS One
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