Honokiol improves cognitive impairment in APP/PS1 mice through activating mitophagy and mitochondrial unfolded protein response

FUNDC1 regulates receptor-mediated mitophagy independently of the PINK1/Parkin-dependent pathway in rotenone-treated SH-SY5Y cells

(2020) Si Yeon Park et al.   FOOD AND CHEMICAL TOXICOLOGY

Honokiol, an active compound of Magnolia officinalis, is involved in restoring normal baroreflex sensitivity in hypercholesterolemic rabbits

(2020) Pei‐Yu Chou et al.   Food Science & Nutrition

Prevention of Cognitive Decline in Alzheimer’s Disease by Novel Antioxidative Supplements

(2020) Koh Tadokoro et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Current understanding of metal ions in the pathogenesis of Alzheimer’s disease

(2020) Lu Wang et al.   Translational Neurodegeneration

Mitophagy: An Emerging Role in Aging and Age-Associated Diseases

(2020) Guo Chen et al.   Frontiers in Cell and Developmental Biology

Accumulation of amyloid precursor protein C-terminal fragments triggers mitochondrial structure, function, and mitophagy defects in Alzheimer’s disease models and human brains

(2020) Loan Vaillant-Beuchot et al.   ACTA NEUROPATHOLOGICA

Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease

(2019) Evandro F. Fang et al.   NATURE NEUROSCIENCE

Mitochondrial dysfunction in Alzheimer's disease: Role in pathogenesis and novel therapeutic opportunities

(2019) Judit M. Perez Ortiz et al.   BRITISH JOURNAL OF PHARMACOLOGY

Dysfunctional Mitochondria and Mitophagy as Drivers of Alzheimer’s Disease Pathogenesis

(2019) Anushka Chakravorty et al.   Frontiers in Aging Neuroscience

Cholesterol impairs autophagy-mediated clearance of amyloid beta while promoting its secretion

(2018) Elisabet Barbero-Camps et al.   Autophagy

Mitophagy and Quality Control Mechanisms in Mitochondrial Maintenance

(2018) Sarah Pickles et al.   CURRENT BIOLOGY

Hippocampal mutant APP and amyloid beta-induced cognitive decline, dendritic spine loss, defective autophagy, mitophagy and mitochondrial abnormalities in a mouse model of Alzheimer’s disease

(2018) Maria Manczak et al.   HUMAN MOLECULAR GENETICS

Mitochondrial Dysfunction as a Predictor and Driver of Alzheimer’s Disease-Like Pathology in OXYS Rats

(2018) Mikhail A. Tyumentsev et al.   JOURNAL OF ALZHEIMERS DISEASE

Honokiol Alleviates Cognitive Deficits of Alzheimer’s Disease (PS1V97L) Transgenic Mice by Activating Mitochondrial SIRT3

(2018) Haitao Li et al.   JOURNAL OF ALZHEIMERS DISEASE

The mitochondrial unfolded protein response and mitohormesis: a perspective on metabolic diseases

(2018) Hyon-Seung Yi et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

SIRT3 activator Honokiol attenuates β-Amyloid by modulating amyloidogenic pathway

(2018) Sindhu Ramesh et al.   PLoS One

Choline ameliorates cardiac hypertrophy by regulating metabolic remodelling and UPRmt through SIRT3-AMPK pathway

(2018) Man Xu et al.   CARDIOVASCULAR RESEARCH

Synaptophysin and Synaptojanin-1 in Down Syndrome are Differentially Affected by Alzheimer's Disease

(2018) Sarah B. Martin et al.   JOURNAL OF ALZHEIMERS DISEASE

Emerging role of SIRT3 in mitochondrial dysfunction and cardiovascular diseases

(2018) Jie Wu et al.   FREE RADICAL RESEARCH

Mitochondrial Dysfunction and Synaptic Transmission Failure in Alzheimer’s Disease

(2017) Lan Guo et al.   JOURNAL OF ALZHEIMERS DISEASE

Enhancing mitochondrial proteostasis reduces amyloid-β proteotoxicity

(2017) Vincenzo Sorrentino et al.   NATURE

Selected mitochondrial DNA landscapes activate the SIRT3 axis of the UPRmt to promote metastasis

(2017) T C Kenny et al.   ONCOGENE

The Role of Mitochondrial Dysfunction in the Progression of Alzheimer’s Disease

(2017) Claus Desler et al.   CURRENT MEDICINAL CHEMISTRY

Intraneuronal aggregation of the β-CTF fragment of APP (C99) induces Aβ-independent lysosomal-autophagic pathology

(2016) Inger Lauritzen et al.   ACTA NEUROPATHOLOGICA

Evidence for Mitochondrial UPR Gene Activation in Familial and Sporadic Alzheimer's Disease

(2016) John S. Beck et al.   Current Alzheimer Research

Protein quality control at the mitochondrion

(2016) W. Voos et al.   Essays in Biochemistry

Protein Kinase Cϵ (PKCϵ) Promotes Synaptogenesis through Membrane Accumulation of the Postsynaptic Density Protein PSD-95

(2016) Abhik Sen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IL-33 ameliorates Alzheimer’s disease-like pathology and cognitive decline

(2016) Amy K. Y. Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deciphering the Molecular Signals of PINK1/Parkin Mitophagy

(2016) Thanh N. Nguyen et al.   TRENDS IN CELL BIOLOGY

ClpX stimulates the mitochondrial unfolded protein response (UPRmt) in mammalian cells

(2015) Natalie Al-Furoukh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Sirtuin-3 (SIRT3) Protein Attenuates Doxorubicin-induced Oxidative Stress and Improves Mitochondrial Respiration in H9c2 Cardiomyocytes

(2015) Kyle G. Cheung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sirtuin 3 regulates Foxo3a-mediated antioxidant pathway in microglia

(2015) P. Rangarajan et al.   NEUROSCIENCE

Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3

(2015) Vinodkumar B. Pillai et al.   Nature Communications

Editorial (Thematic Issue: Mitochondrial Biogenesis: Pharmacological Approaches)

(2014) Teresa Valero   CURRENT PHARMACEUTICAL DESIGN

Antiaging Properties of a Grape-Derived Antioxidant Are Regulated by Mitochondrial Balance of Fusion and Fission Leading to Mitophagy Triggered by a Signaling Network of Sirt1-Sirt3-Foxo3-PINK1-PARKIN

(2014) Somak Das et al.   Oxidative Medicine and Cellular Longevity

After the banquet

(2013) Jianhui Zhu et al.   Autophagy

Genetic mouse models of brain ageing and Alzheimer's disease

(2013) Andras Bilkei-Gorzo   PHARMACOLOGY & THERAPEUTICS

Neuro-Modulating Effects of Honokiol: A Review

(2013) Anna Woodbury et al.   Frontiers in Neurology

Bioenergetic role of mitochondrial fusion and fission

(2012) Benedikt Westermann   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS