Therapeutic targets of neuroprotection and neurorestoration in ischemic stroke: Applications for natural compounds from medicinal herbs

Folium Ginkgo extract and tetramethylpyrazine sodium chloride injection (Xingxiong injection) protects against focal cerebral ischaemia/reperfusion injury via activating the Akt/Nrf2 pathway and inhibiting NLRP3 inflammasome activation

(2022) Ting Zhu et al.   PHARMACEUTICAL BIOLOGY

Salidroside Inhibits Reactive Astrogliosis and Glial Scar Formation in Late Cerebral Ischemia via the Akt/GSK-3β Pathway

(2021) Chengya Dong et al.   NEUROCHEMICAL RESEARCH

Astragaloside IV promotes microglia/macrophages M2 polarization and enhances neurogenesis and angiogenesis through PPARγ pathway after cerebral ischemia/reperfusion injury in rats

(2021) Lin Li et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Effects of notoginseng leaf triterpenes on small molecule metabolism after cerebral ischemia/reperfusion injury assessed using MALDI–MS imaging

(2021) Lei Wang et al.   Annals of Translational Medicine

Icariin enhance mild hypothermia-induced neuroprotection via inhibiting the activation of NF-κB in experimental ischemic stroke

(2021) Mingming Dai et al.   METABOLIC BRAIN DISEASE

Gastrodin Alleviates Cerebral Ischaemia/Reperfusion Injury by Inhibiting Pyroptosis by Regulating the lncRNA NEAT1/miR-22-3p Axis

(2021) Heng-Sheng Zhang et al.   NEUROCHEMICAL RESEARCH

Classical Active Ingredients and Extracts of Chinese Herbal Medicines: Pharmacokinetics, Pharmacodynamics, and Molecular Mechanisms for Ischemic Stroke

(2021) Ting Zhu et al.   Oxidative Medicine and Cellular Longevity

Protective effects of Astragaloside IV against oxidative injury and apoptosis in cultured astrocytes by regulating Nrf2/JNK signaling

(2021) Jintao Yang et al.   EXPERIMENTAL BRAIN RESEARCH

Efficacy and Safety of Panax Notoginseng Saponins (Xueshuantong) in Patients With Acute Ischemic Stroke (EXPECT) Trial: Rationale and Design

(2021) Luda Feng et al.   Frontiers in Pharmacology

Resveratrol-mediated neurorestoration after cerebral ischemic injury - Sonic Hedgehog signaling pathway

(2021) Pingping Yu et al.   LIFE SCIENCES

SETD3 Downregulation Mediates PTEN Upregulation-Induced Ischemic Neuronal Death Through Suppression of Actin Polymerization and Mitochondrial Function

(2021) Xiangyu Xu et al.   MOLECULAR NEUROBIOLOGY

Metabolomic Profiling of the Synergistic Effects of Ginsenoside Rg1 in Combination with Neural Stem Cell Transplantation in Ischemic Stroke Rats

(2020) Jian Gao et al.   JOURNAL OF PROTEOME RESEARCH

Astragaloside IV Exerts Cognitive Benefits and Promotes Hippocampal Neurogenesis in Stroke Mice by Downregulating Interleukin-17 Expression via Wnt Pathway

(2020) Li Sun et al.   Frontiers in Pharmacology

Fibroblast growth factor 2 contributes to the effect of salidroside on dendritic and synaptic plasticity after cerebral ischemia/reperfusion injury

(2020) Sisi Li et al.   Aging-US

Effect of fluoxetine on HIF-1α- Netrin/VEGF cascade, angiogenesis and neuroprotection in a rat model of transient middle cerebral artery occlusion

(2020) Qimin Hu et al.   EXPERIMENTAL NEUROLOGY

Icariin protects neurons from endoplasmic reticulum stress-induced apoptosis after OGD/R injury via suppressing IRE1α-XBP1 signaling pathway

(2020) Zhen-tao Mo et al.   LIFE SCIENCES

Baicalin combats glutamate excitotoxicity via protecting glutamine synthetase from ROS-induced 20S proteasomal degradation

(2020) Xianrui Song et al.   Redox Biology

Antagonistic effects of IL-17 and Astragaloside IV on cortical neurogenesis and cognitive behavior after stroke in adult mice through Akt/GSK-3β pathway

(2020) Li Sun et al.   Cell Death Discovery

Notoginseng Leaf Triterpenes Ameliorates OGD/R-Induced Neuronal Injury via SIRT1/2/3-Foxo3a-MnSOD/PGC-1α Signaling Pathways Mediated by the NAMPT-NAD Pathway

(2020) Weijie Xie et al.   Oxidative Medicine and Cellular Longevity

Breviscapine Alleviates Cognitive Impairments Induced by Transient Cerebral Ischemia/Reperfusion through Its Anti-Inflammatory and Anti-Oxidant Properties in a Rat Model

(2020) Yinghua Li et al.   ACS Chemical Neuroscience

Xuesaitong injection (lyophilized) combined with aspirin and clopidogrel protect against focal cerebral ischemic/reperfusion injury in rats by suppressing oxidative stress and inflammation and regulating the NOX2/IL-6/STAT3 pathway

(2020) Ting Zhu et al.   Annals of Palliative Medicine

Antioxidant effects of ginkgolides and bilobalide against cerebral ischemia injury by activating the Akt/Nrf2 pathway in vitro and in vivo

(2019) Qiu Liu et al.   CELL STRESS & CHAPERONES

NLRP3 inflammasome in ischemic stroke: As possible therapeutic target

(2019) Masoumeh Alishahi et al.   International Journal of Stroke

The Role of Astragaloside IV against Cerebral Ischemia/Reperfusion Injury: Suppression of Apoptosis via Promotion of P62-LC3-Autophagy

(2019) Yi Zhang et al.   MOLECULES

Astragaloside IV Protects Primary Cerebral Cortical Neurons from Oxygen and Glucose Deprivation/Reoxygenation by Activating the PKA/CREB Pathway

(2019) Bingjie Xue et al.   NEUROSCIENCE

NKT Cells in Neurological Diseases

(2019) Yu Cui et al.   Frontiers in Cellular Neuroscience

Dual Functions of Microglia in Ischemic Stroke

(2019) Chuan Qin et al.   Neuroscience Bulletin

Apoptosis regulation in the penumbra after ischemic stroke: expression of pro- and antiapoptotic proteins

(2019) Anatoly B. Uzdensky   APOPTOSIS

Post-stroke gastrodin treatment ameliorates ischemic injury and increases neurogenesis and restores the Wnt/β-Catenin signaling in focal cerebral ischemia in mice

(2019) Cai-Wei Qiu et al.   BRAIN RESEARCH

Ginsenoside Rg1 attenuates protein aggregation and inflammatory response following cerebral ischemia and reperfusion injury

(2019) Tianyang Zheng et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Salidroside Reduces Inflammation and Brain Injury After Permanent Middle Cerebral Artery Occlusion in Rats by Regulating PI3K/PKB/Nrf2/NFκB Signaling Rather than Complement C3 Activity

(2019) X. Zhang et al.   INFLAMMATION

Gastrodin Inhibits Inflammasome Through the STAT3 Signal Pathways in TNA2 Astrocytes and Reactive Astrocytes in Experimentally Induced Cerebral Ischemia in Rats

(2019) Yue Sui et al.   NEUROMOLECULAR MEDICINE

Catalpol may improve axonal growth via regulating miR-124 regulated PI3K/AKT/mTOR pathway in neurons after ischemia

(2019) Huifeng Zhu et al.   Annals of Translational Medicine

Ginsenoside Rg1 promotes cerebral angiogenesis via the PI3K/Akt/mTOR signaling pathway in ischemic mice

(2019) Junmin Chen et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Curcumin prevents brain damage and cognitive dysfunction during ischemic-reperfusion through the regulation of miR-7-5p

(2019) Hui Xu et al.   CURRENT NEUROVASCULAR RESEARCH

PINK1 overexpression protects against cerebral ischemia through Parkin regulation

(2019) Youliang Wen et al.   ENVIRONMENTAL TOXICOLOGY

Salidroside Restores an Anti-inflammatory Endothelial Phenotype by Selectively Inhibiting Endothelial Complement After Oxidative Stress

(2019) Y Wang et al.   INFLAMMATION

Ischaemic stroke

(2019) Bruce C. V. Campbell et al.   Nature Reviews Disease Primers

Angelica polysaccharide ameliorates memory impairment in Alzheimer’s disease rat through activating BDNF/TrkB/CREB pathway

(2019) Qian Du et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Resveratrol promoted the M2 polarization of microglia and reduced neuroinflammation after cerebral ischemia by inhibiting miR-155

(2019) Shan Ma et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Astragaloside IV alleviates ischemia reperfusion-induced apoptosis by inhibiting the activation of key factors in death receptor pathway and mitochondrial pathway

(2019) Fei Yin et al.   JOURNAL OF ETHNOPHARMACOLOGY

Gastrodin combined with rhynchophylline inhibits cerebral ischaemia-induced inflammasome activation via upregulating miR-21–5p and miR-331–5p

(2019) Heng-Sheng Zhang et al.   LIFE SCIENCES

Catalpol Enhances Neurogenesis And Inhibits Apoptosis Of New Neurons Via BDNF, But Not The BDNF/Trkb Pathway

(2019) Hui-Feng Zhu et al.   Drug Design Development and Therapy

Neuroprotective Effects of Salidroside on Cerebral Ischemia/Reperfusion-Induced Behavioral Impairment Involves the Dopaminergic System

(2019) Zhi-feng Zhong et al.   Frontiers in Pharmacology

Catalpol induces cell activity to promote axonal regeneration via the PI3K/AKT/mTOR pathway in vivo and in vitro stroke model

(2019) Jinghuan Wang et al.   Annals of Translational Medicine

Curcumin protects cortical neurons against oxygen and glucose deprivation/reoxygenation injury through flotillin-1 and extracellular signal-regulated kinase1/2 pathway

(2018) Zhengyu Lu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mechanism of salvianolic acid B neuroprotection against ischemia/reperfusion induced cerebral injury

(2018) Yong Fan et al.   BRAIN RESEARCH

Resveratrol Treatment in Different Time-Attenuated Neuronal Apoptosis After Oxygen and Glucose Deprivation/Reoxygenation via Enhancing the Activation of Nrf-2 Signaling Pathway In Vitro

(2018) Jun Yang et al.   CELL TRANSPLANTATION

Enhanced permeability of blood–brain barrier and targeting function of brain via borneol-modified chemically solid lipid nanoparticle

(2018) Hui Song et al.   International Journal of Nanomedicine

Salidroside provides neuroprotection by modulating microglial polarization after cerebral ischemia

(2018) Xiangrong Liu et al.   Journal of Neuroinflammation

Upregulation of miR-216a exerts neuroprotective effects against ischemic injury through negatively regulating JAK2/STAT3-involved apoptosis and inflammatory pathways

(2018) Yu Shuang Tian et al.   JOURNAL OF NEUROSURGERY

Combined acupuncture and HuangDiSan treatment affects behavior and synaptophysin levels in the hippocampus of senescence-accelerated mouse prone 8 after neural stem cell transplantation

(2018) Lan Zhao et al.   Neural Regeneration Research

Puerarin protects rat brain against ischemia/reperfusion injury by suppressing autophagy via the AMPK-mTOR-ULK1 signaling pathway

(2018) Zhi-Gang Mei et al.   Neural Regeneration Research

Cell-based and pharmacological neurorestorative therapies for ischemic stroke

(2018) Poornima Venkat et al.   NEUROPHARMACOLOGY

Advances in stroke pharmacology

(2018) Zhenhua Zhou et al.   PHARMACOLOGY & THERAPEUTICS

Autophagy in ischemic stroke

(2018) Pei Wang et al.   PROGRESS IN NEUROBIOLOGY

Curcumin protects neural cells against ischemic injury in N2a cells and mouse brain with ischemic stroke

(2018) Cai-Jun Xie et al.   Brain and Behavior

Ginsenoside Rg1 protects against ischemic/reperfusion-induced neuronal injury through miR-144/Nrf2/ARE pathway

(2018) Shi-feng Chu et al.   ACTA PHARMACOLOGICA SINICA

Salidroside alleviates ischemic brain injury in mice with ischemic stroke through regulating BDNK mediated PI3K/Akt pathway

(2018) Xu Zhang et al.   BIOCHEMICAL PHARMACOLOGY

Current advances in ischemic stroke research and therapies

(2018) Derek Barthels et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Icariin and mesenchymal stem cells synergistically promote angiogenesis and neurogenesis after cerebral ischemia via PI3K and ERK1/2 pathways

(2018) Dandan Liu et al.   BIOMEDICINE & PHARMACOTHERAPY

Supramolecular Nanostructure Activates TrkB Receptor Signaling of Neuronal Cells by Mimicking Brain-Derived Neurotrophic Factor

(2018) Alexandra N. Edelbrock et al.   NANO LETTERS

Resveratrol attenuates brain damage in permanent focal cerebral ischemia via activation of PI3K/Akt signaling pathway in rats

(2018) Junrong Lei et al.   NEUROLOGICAL RESEARCH

Gastrodin exerts robust neuroprotection in the postischemic brain via its protective effect against Zn2+-toxicity and its anti-oxidative effects in astrocytes

(2018) Lidan Luo et al.   Animal Cells and Systems

Upregulation of AMPK by 4-O-methylascochlorin promotes autophagy via the HIF-1α expression

(2018) Ji-Young Seok et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Astragaloside IV reduces neuronal apoptosis and parthanatos in ischemic injury by preserving mitochondrial hexokinase-II

(2018) Ying Li et al.   FREE RADICAL BIOLOGY AND MEDICINE

Baicalin attenuates in vivo and in vitro hyperglycemia-exacerbated ischemia/reperfusion injury by regulating mitochondrial function in a manner dependent on AMPK

(2017) Shanshan Li et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Molecular, cellular and functional events in axonal sprouting after stroke

(2017) S. Thomas Carmichael et al.   EXPERIMENTAL NEUROLOGY

Salidroside Inhibits Inflammation Through PI3K/Akt/HIF Signaling After Focal Cerebral Ischemia in Rats

(2017) Yicong Wei et al.   INFLAMMATION

Neuroprotective Effect of Curcumin Against Cerebral Ischemia-Reperfusion Via Mediating Autophagy and Inflammation

(2017) Lifa Huang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Protective effects of ginsenoside Rg1 against oxygen-glucose-deprivation-induced apoptosis in neural stem cells

(2017) Yiwen Li et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Potential therapeutic and protective effect of curcumin against stroke in the male albino stroke-induced model rats

(2017) Yuanyuan Zhang et al.   LIFE SCIENCES

Curcumin prevents reperfusion injury following ischemic stroke in rats via inhibition of NF-κB, ICAM-1, MMP-9 and caspase-3 expression

(2017) Wei Li et al.   Molecular Medicine Reports

Baicalin protects neonatal rat brains against hypoxic-ischemic injury by upregulating glutamate transporter 1 via the phosphoinositide 3-kinase/protein kinase B signaling pathway

(2017) Xiao-hua Yan et al.   Neural Regeneration Research

Puerarin provides a neuroprotection against transient cerebral ischemia by attenuating autophagy at the ischemic penumbra in neurons but not in astrocytes

(2017) He Hongyun et al.   NEUROSCIENCE LETTERS

Administration of follicle-stimulating hormone induces autophagy via upregulation of HIF-1α in mouse granulosa cells

(2017) Jilong Zhou et al.   Cell Death & Disease

Puerarin attenuates locomotor and cognitive deficits as well as hippocampal neuronal injury through the PI3K/Akt1/GSK-3β signaling pathway in an in vivo model of cerebral ischemia

(2017) Jinhao Tao et al.   Oncotarget

Hormetic effect of panaxatriol saponins confers neuroprotection in PC12 cells and zebrafish through PI3K/AKT/mTOR and AMPK/SIRT1/FOXO3 pathways

(2017) Chao Zhang et al.   Scientific Reports

Curcumin Protects against Ischemic Stroke by Titrating Microglia/Macrophage Polarization

(2017) Zongjian Liu et al.   Frontiers in Aging Neuroscience

Baicalin Attenuates Blood-Brain Barrier Disruption and Hemorrhagic Transformation and Improves Neurological Outcome in Ischemic Stroke Rats with Delayed t-PA Treatment: Involvement of ONOO−-MMP-9 Pathway

(2017) Hansen Chen et al.   Translational Stroke Research

Curcumin pretreatment attenuates inflammation and mitochondrial dysfunction in experimental stroke: The possible role of Sirt1 signaling

(2016) Yanping Miao et al.   BRAIN RESEARCH BULLETIN

Resveratrol provides neuroprotection by inhibiting phosphodiesterases and regulating the cAMP/AMPK/SIRT1 pathway after stroke in rats

(2016) Dan Wan et al.   BRAIN RESEARCH BULLETIN

Ginkgolide B Protects Against Ischemic Stroke Via Modulating Microglia Polarization in Mice

(2016) Zhao-Ma Shu et al.   CNS Neuroscience & Therapeutics

Salvianolic Acid B Ameliorates Cerebral Ischemia/Reperfusion Injury Through Inhibiting TLR4/MyD88 Signaling Pathway

(2016) Yujue Wang et al.   INFLAMMATION

Icariin attenuates cerebral ischemia–reperfusion injury through inhibition of inflammatory response mediated by NF-κB, PPARα and PPARγ in rats

(2016) Deqing Xiong et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Defending the mitochondria: The pathways of mitophagy and mitochondrial-derived vesicles

(2016) Rosalind F. Roberts et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Catalpol stimulates VEGF production via the JAK2/STAT3 pathway to improve angiogenesis in rats’ stroke model

(2016) Wan Dong et al.   JOURNAL OF ETHNOPHARMACOLOGY

Neuroprotection in acute stroke: targeting excitotoxicity, oxidative and nitrosative stress, and inflammation

(2016) Ángel Chamorro et al.   LANCET NEUROLOGY

Curcumin by down-regulating NF-kB and elevating Nrf2, reduces brain edema and neurological dysfunction after cerebral I/R

(2016) Wei Li et al.   MICROVASCULAR RESEARCH

Resveratrol pretreatment attenuates injury and promotes proliferation of neural stem cells following oxygen-glucose deprivation/reoxygenation by upregulating the expression of Nrf2, HO-1 and NQO1 in vitro

(2016) Changbo Shen et al.   Molecular Medicine Reports

Gastrodin ameliorates subacute phase cerebral ischemia-reperfusion injury by inhibiting inflammation and apoptosis in rats

(2016) Bo Liu et al.   Molecular Medicine Reports

Resveratrol Pretreatment Decreases Ischemic Injury and Improves Neurological Function Via Sonic Hedgehog Signaling After Stroke in Rats

(2016) Pingping Yu et al.   MOLECULAR NEUROBIOLOGY

Curcumin protects against stroke and increases levels of Notch intracellular domain

(2016) Shuang Liu et al.   NEUROLOGICAL RESEARCH

Resveratrol protects CA1 neurons against focal cerebral ischemic reperfusion-induced damage via the ERK-CREB signaling pathway in rats

(2016) Zhen Li et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Angiogenesis in Ischemic Stroke and Angiogenic Effects of Chinese Herbal Medicine

(2016) Sai-Wang Seto et al.   Journal of Clinical Medicine

Effect of Baicalin-loaded PEGylated cationic solid lipid nanoparticles modified by OX26 antibody on regulating the levels of baicalin and amino acids during cerebral ischemia–reperfusion in rats

(2015) Zhidong Liu et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Forkhead box O transcription factors as possible mediators in the development of major depression

(2015) Haitao Wang et al.   NEUROPHARMACOLOGY

Possible mechanism of PNS protection against cisplatin-induced nephrotoxicity in rat models

(2015) Xinwen Liu et al.   TOXICOLOGY MECHANISMS AND METHODS

Possible mechanism of PNS protection against cisplatin-induced nephrotoxicity in rat models

(2015) Xinwen Liu et al.   TOXICOLOGY MECHANISMS AND METHODS

Role of vascular endothelial growth factor and other growth factors in post-stroke recovery

(2014) Madakasira VasanthaPadma Srivastava et al.   Annals of Indian Academy of Neurology

Intracellular NAMPT–NAD+–SIRT1 cascade improves post-ischaemic vascular repair by modulating Notch signalling in endothelial progenitors

(2014) Pei Wang et al.   CARDIOVASCULAR RESEARCH

BNIP3 Interacting with LC3 Triggers Excessive Mitophagy in Delayed Neuronal Death in Stroke

(2014) Ruo-Yang Shi et al.   CNS Neuroscience & Therapeutics

Intermittent fasting attenuates inflammasome activity in ischemic stroke

(2014) David Yang-Wei Fann et al.   EXPERIMENTAL NEUROLOGY

Current perspectives on the link between neuroinflammation and neurogenesis

(2014) Brian Wang et al.   METABOLIC BRAIN DISEASE

Found in Translation

(2014) Ulrich Dirnagl et al.   STROKE

The role of astrocytes in mediating exogenous cell-based restorative therapy for stroke

(2013) Yi Li et al.   GLIA

Efficacy of Single and Multiple Injections of Human Umbilical Tissue-Derived Cells following Experimental Stroke in Rats

(2013) Amjad Shehadah et al.   PLoS One

Vascular remodeling after ischemic stroke: Mechanisms and therapeutic potentials

(2013) Jialing Liu et al.   PROGRESS IN NEUROBIOLOGY

Excitotoxicity and stroke: Identifying novel targets for neuroprotection

(2013) Ted Weita Lai et al.   PROGRESS IN NEUROBIOLOGY

Role of neural precursor cells in promoting repair following stroke

(2012) Pooya Dibajnia et al.   ACTA PHARMACOLOGICA SINICA

Achievements and perspectives in yeast acetic acid-induced programmed cell death pathways

(2012) Nicoletta Guaragnella et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Baicalin improved the spatial learning ability of global ischemia/reperfusion rats by reducing hippocampal apoptosis

(2012) Oumei Cheng et al.   BRAIN RESEARCH

Neuroprotection for Stroke: Current Status and Future Perspectives

(2012) Jens Minnerup et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nitric Oxide: Considerations for the Treatment of Ischemic Stroke

(2012) Nicole A Terpolilli et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Baicalin Improves Survival in a Murine Model of Polymicrobial Sepsis via Suppressing Inflammatory Response and Lymphocyte Apoptosis

(2012) Jiali Zhu et al.   PLoS One

Autophagy and Aging

(2011) David C. Rubinsztein et al.   CELL

Increased p38 mitogen-activated protein kinase signaling is involved in the oxidative stress associated with oxygen and glucose deprivation in neonatal hippocampal slice cultures

(2011) Qing Lu et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Calcium, ischemia and excitotoxicity

(2010) Kinga Szydlowska et al.   CELL CALCIUM

Mechanisms of cerebral edema in traumatic brain injury: therapeutic developments

(2010) James J Donkin et al.   CURRENT OPINION IN NEUROLOGY

Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney

(2010) Shinji Kume et al.   JOURNAL OF CLINICAL INVESTIGATION

An age-related sprouting transcriptome provides molecular control of axonal sprouting after stroke

(2010) Songlin Li et al.   NATURE NEUROSCIENCE

Angiogenesis after cerebral ischemia

(2009) Heike Beck et al.   ACTA NEUROPATHOLOGICA

Vascular Endothelial Growth Factor Receptor 2 Controls Blood Pressure by Regulating Nitric Oxide Synthase Expression

(2009) Carie S. Facemire et al.   HYPERTENSION

Neurorestorative therapies for stroke: underlying mechanisms and translation to the clinic

(2009) Zheng Gang Zhang et al.   LANCET NEUROLOGY

Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains

(2009) G. Bellot et al.   MOLECULAR AND CELLULAR BIOLOGY

Apoptotic Mechanisms After Cerebral Ischemia

(2009) Brad R.S. Broughton et al.   STROKE

Neurogenesis directed by Sirt1

(2008) Sergiy Libert et al.   NATURE CELL BIOLOGY