Resveratrol-mediated neurorestoration after cerebral ischemic injury - Sonic Hedgehog signaling pathway

Resveratrol Reserved Hypoxia-Ischemia Induced Childhood Hippocampal Dysfunction and Neurogenesis via Improving Mitochondrial Dynamics

(2019) Hong Li et al.   NEUROSCIENCE RESEARCH

The Fluid Aspect of the Mediterranean Diet in the Prevention and Management of Cardiovascular Disease and Diabetes: The Role of Polyphenol Content in Moderate Consumption of Wine and Olive Oil

(2019) Paola Ditano-Vázquez et al.   Nutrients

Effect of Endovascular Contact Aspiration vs Stent Retriever on Revascularization in Patients With Acute Ischemic Stroke and Large Vessel Occlusion

(2017) Bertrand Lapergue et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Poststroke Sonic Hedgehog Agonist Treatment Improves Functional Recovery by Enhancing Neurogenesis and Angiogenesis

(2017) Yongming Jin et al.   STROKE

Mitochondria-Targeted Antioxidants Protect Against Amyloid-β Toxicity in Alzheimer's Disease Neurons

(2017) Maria Manczak et al.   JOURNAL OF ALZHEIMERS DISEASE

Resveratrol limits diabetes-associated cognitive decline in rats by preventing oxidative stress and inflammation and modulating hippocampal structural synaptic plasticity

(2016) Xia Tian et al.   BRAIN RESEARCH

Sonic hedgehog is a regulator of extracellular glutamate levels and epilepsy

(2016) Shengjie Feng et al.   EMBO REPORTS

Resveratrol suppresses glial activation and alleviates trigeminal neuralgia via activation of AMPK

(2016) Yan-jing Yang et al.   Journal of Neuroinflammation

Resveratrol pretreatment attenuates injury and promotes proliferation of neural stem cells following oxygen-glucose deprivation/reoxygenation by upregulating the expression of Nrf2, HO-1 and NQO1 in vitro

(2016) Changbo Shen et al.   Molecular Medicine Reports

Neuroprotective effects of resveratrol against traumatic brain injury in rats: Involvement of synaptic proteins and neuronal autophagy

(2016) YAN FENG et al.   Molecular Medicine Reports

Resveratrol Promotes Remyelination in Cuprizone Model of Multiple Sclerosis: Biochemical and Histological Study

(2016) Heba R. Ghaiad et al.   MOLECULAR NEUROBIOLOGY

Resveratrol Pretreatment Decreases Ischemic Injury and Improves Neurological Function Via Sonic Hedgehog Signaling After Stroke in Rats

(2016) Pingping Yu et al.   MOLECULAR NEUROBIOLOGY

Effect of Melatonin and Resveratrol against Memory Impairment and Hippocampal Damage in a Rat Model of Vascular Dementia

(2016) Dongfang Shen et al.   NEUROIMMUNOMODULATION

Chronic administration of resveratrol prevents morphological changes in prefrontal cortex and hippocampus of aged rats

(2016) Elizabeth Monserrat Hernández-Hernández et al.   SYNAPSE

Resveratrol post-treatment protects against neonatal brain injury after hypoxia-ischemia

(2016) Shulin Pan et al.   Oncotarget

Resveratrol counteracts lipopolysaccharide-induced depressive-like behaviors via enhanced hippocampal neurogenesis

(2016) Liang Liu et al.   Oncotarget

Sonic hedgehog stimulates neurite outgrowth in a mechanical stretch model of reactive-astrogliosis

(2016) Antonio Berretta et al.   Scientific Reports

Rehabilitation Training and Resveratrol Improve the Recovery of Neurological and Motor Function in Rats after Cerebral Ischemic Injury through the Sirt1 Signaling Pathway

(2016) Na Shi et al.   Biomed Research International

Dose-dependent short- and long-term effects of ionizing irradiation on neural stem cells in murine hippocampal tissue cultures: neuroprotective potential of resveratrol

(2016) Isabell Prager et al.   Brain and Behavior

Differential responses of Trans-Resveratrol on proliferation of neural progenitor cells and aged rat hippocampal neurogenesis

(2016) Vivek Kumar et al.   Scientific Reports

Protective effects of resveratrol on the inhibition of hippocampal neurogenesis induced by ethanol during early postnatal life

(2015) Le Xu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Resveratrol downregulates type-1 glutamate transporter expression and microglia activation in the hippocampus following cerebral ischemia reperfusion in rats

(2015) Catrinel Girbovan et al.   BRAIN RESEARCH

Resveratrol Rescues the Impairments of Hippocampal Neurons Stimulated by Microglial Over-Activation In Vitro

(2015) Feng Wang et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Sonic Hedgehog Signaling Mediates Resveratrol to Increase Proliferation of Neural Stem Cells After Oxygen-Glucose Deprivation/Reoxygenation Injury in Vitro

(2015) Wei Cheng et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Notch Activity Modulates the Responsiveness of Neural Progenitors to Sonic Hedgehog Signaling

(2015) Jennifer H. Kong et al.   DEVELOPMENTAL CELL

Sonic Hedgehog Promotes Neurite Outgrowth of Primary Cortical Neurons Through Up-Regulating BDNF Expression

(2015) Weiliang He et al.   NEUROCHEMICAL RESEARCH

Resveratrol Preconditioning Protects Against Cerebral Ischemic Injury via Nuclear Erythroid 2–Related Factor 2

(2015) Srinivasan V. Narayanan et al.   STROKE

Resveratrol Prevents Age-Related Memory and Mood Dysfunction with Increased Hippocampal Neurogenesis and Microvasculature and Reduced Glial Activation

(2015) Maheedhar Kodali et al.   Scientific Reports

The Shh Signaling Pathway Is Upregulated in Multiple Cell Types in Cortical Ischemia and Influences the Outcome of Stroke in an Animal Model

(2015) Yongmin Jin et al.   PLoS One

A BCL6/BCOR/SIRT1 Complex Triggers Neurogenesis and Suppresses Medulloblastoma by Repressing Sonic Hedgehog Signaling

(2014) Luca Tiberi et al.   CANCER CELL

Primary cilia mediate sonic hedgehog signaling to regulate neuronal-like differentiation of bone mesenchymal stem cells for resveratrol induction in vitro

(2014) Jia-Gui Huang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Inhibitor of Differentiation-1 and Hypoxia-Inducible Factor-1 Mediate Sonic Hedgehog Induction by Amyloid Beta-Peptide in Rat Cortical Neurons

(2014) Yu-Hsing Hung et al.   MOLECULAR NEUROBIOLOGY

A Smoothened receptor agonist is neuroprotective and promotes regeneration after ischemic brain injury

(2014) O V Chechneva et al.   Cell Death & Disease

Investigations of Curcumin and Resveratrol on Neurite Outgrowth: Perspectives on Spinal Muscular Atrophy

(2014) Gamze Bora-Tatar et al.   Biomed Research International

Resveratrol Exacerbates Both Autoimmune and Viral Models of Multiple Sclerosis

(2013) Fumitaka Sato et al.   AMERICAN JOURNAL OF PATHOLOGY

Anti-oxidative, anti-apoptotic, and pro-angiogenic effects mediate functional improvement by sonic hedgehog against focal cerebral ischemia in rats

(2013) Shiang-Suo Huang et al.   EXPERIMENTAL NEUROLOGY

NAD+ acts on mitochondrial SirT3 to prevent axonal caspase activation and axonal degeneration

(2013) Sébastien Magnifico et al.   FASEB JOURNAL

Resveratrol improves postnatal hippocampal neurogenesis and brain derived neurotrophic factor in prenatally stressed rats

(2013) Sampath Madhyastha et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

The Sonic Hedgehog Pathway Mediates Brain Plasticity and Subsequent Functional Recovery After Bone Marrow Stromal Cell Treatment of Stroke in Mice

(2013) Xiaoshuang Ding et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Synapto-Protective Drugs Evaluation in Reconstructed Neuronal Network

(2013) Bérangère Deleglise et al.   PLoS One

Sonic Hedgehog Signaling Pathway Mediates Cerebrolysin-Improved Neurological Function After Stroke

(2013) Li Zhang et al.   STROKE

Impaired adenosine monophosphate-activated protein kinase signalling in dorsal root ganglia neurons is linked to mitochondrial dysfunction and peripheral neuropathy in diabetes

(2012) Subir K. Roy Chowdhury et al.   BRAIN

Resveratrol, A Neuroprotective Supplement for Alzheimer's Disease

(2012) Fei Li et al.   CURRENT PHARMACEUTICAL DESIGN

Improvement of neurological recovery and stimulation of neural progenitor cell proliferation by intrathecal administration of Sonic hedgehog

(2012) Nicholas C. Bambakidis et al.   JOURNAL OF NEUROSURGERY

Sonic Hedgehog Regulates Brain‐Derived Neurotrophic Factor in Normal and Regenerating Cavernous Nerves

(2012) Christopher W. Bond et al.   Journal of Sexual Medicine

tPA and warfarin: Time to move forward

(2012) M. J. Alberts et al.   NEUROLOGY

Bioavailability of resveratrol

(2011) Thomas Walle   Annals of the New York Academy of Sciences

Resveratrol Improves Hippocampal Atrophy in Chronic Fatigue Mice by Enhancing Neurogenesis and Inhibiting Apoptosis of Granular Cells

(2011) Junji Moriya et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Oligodendrogenesis in the subventricular zone and the role of epidermal growth factor

(2011) Oscar Gonzalez-Perez et al.   BRAIN RESEARCH REVIEWS

Resveratrol Pretreatment Attenuates Cerebral Ischemic Injury by Upregulating Expression of Transcription Factor Nrf2 and HO-1 in Rats

(2011) Junwei Ren et al.   NEUROCHEMICAL RESEARCH

Inhibition of sonic hedgehog signaling aggravates brain damage associated with the down-regulation of Gli1, Ptch1 and SOD1 expression in acute ischemic stroke

(2011) Hui Ji et al.   NEUROSCIENCE LETTERS

Protein deacetylase SIRT1 in the cytoplasm promotes nerve growth factor-induced neurite outgrowth in PC12 cells

(2010) Toshiya Sugino et al.   FEBS LETTERS