Ginsenoside Rg1 protects against ischemic/reperfusion-induced neuronal injury through miR-144/Nrf2/ARE pathway

A Dual AMPK/Nrf2 Activator Reduces Brain Inflammation After Stroke by Enhancing Microglia M2 Polarization

(2018) Yunjie Wang et al.   ANTIOXIDANTS & REDOX SIGNALING

Nrf2/ARE pathway inhibits ROS-induced NLRP3 inflammasome activation in BV2 cells after cerebral ischemia reperfusion

(2017) Xiujian Xu et al.   INFLAMMATION RESEARCH

Inhibition of microRNA-153 protects neurons against ischemia/reperfusion injury in an oxygen-glucose deprivation and reoxygenation cellular model by regulating Nrf2/HO-1 signaling

(2017) Qiong Ji et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

IMM-H004, A New Coumarin Derivative, Improved Focal Cerebral Ischemia via Blood–Brain Barrier Protection in Rats

(2017) Fei Niu et al.   Journal of Stroke & Cerebrovascular Diseases

Protective effects of ginsenoside Rg1 against oxygen-glucose-deprivation-induced apoptosis in neural stem cells

(2017) Yiwen Li et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

MicroRNA-144 modulates oxidative stress tolerance in SH-SY5Y cells by regulating nuclear factor erythroid 2-related factor 2-glutathione axis

(2017) Chunlei Zhou et al.   NEUROSCIENCE LETTERS

Angiotensin II Peptide Vaccine Protects Ischemic Brain Through Reducing Oxidative Stress

(2017) Kouji Wakayama et al.   STROKE

IMM-H004, A New Coumarin Derivative, Improved Focal Cerebral Ischemia via Blood–Brain Barrier Protection in Rats

(2017) Fei Niu et al.   Journal of Stroke & Cerebrovascular Diseases

Sodium Sulfide Attenuates Ischemic-Induced Heart Failure by Enhancing Proteasomal Function in an Nrf2-Dependent MannerCLINICAL PERSPECTIVE

(2016) Yuuki Shimizu et al.   Circulation-Heart Failure

Antioxidant activities of ginsenoside Rg1 against cisplatin-induced hepatic injury through Nrf2 signaling pathway in mice

(2016) Yan Gao et al.   FREE RADICAL RESEARCH

Upregulating the Expression of Survivin-HBXIP Complex Contributes to the Protective Role of IMM-H004 in Transient Global Cerebral Ischemia/Reperfusion

(2016) Shi-Feng Chu et al.   MOLECULAR NEUROBIOLOGY

An Antagomir to MicroRNA-106b-5p Ameliorates Cerebral Ischemia and Reperfusion Injury in Rats Via Inhibiting Apoptosis and Oxidative Stress

(2016) Pengfei Li et al.   MOLECULAR NEUROBIOLOGY

Nrf2—a Promising Therapeutic Target for Defensing Against Oxidative Stress in Stroke

(2016) Rongrong Zhang et al.   MOLECULAR NEUROBIOLOGY

Ginsenoside Rg1 attenuates motor impairment and neuroinflammation in the MPTP-probenecid-induced parkinsonism mouse model by targeting α-synuclein abnormalities in the substantia nigra

(2016) Yang Heng et al.   TOXICOLOGY LETTERS

Pathophysiology and Treatments of Oxidative Injury in Ischemic Stroke: Focus on the Phagocytic NADPH Oxidase 2

(2015) Federico Carbone et al.   ANTIOXIDANTS & REDOX SIGNALING

Inhibiting microRNA-144 abates oxidative stress and reduces apoptosis in hearts of streptozotocin-induced diabetic mice

(2015) Manli Yu et al.   CARDIOVASCULAR PATHOLOGY

Epigenetic regulation of Keap1-Nrf2 signaling

(2015) Yue Guo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Recent advances in ginseng as cancer therapeutics: a functional and mechanistic overview

(2015) Alice S. T. Wong et al.   NATURAL PRODUCT REPORTS

Tanshinone IIA protects dopaminergic neurons against 6-hydroxydopamine-induced neurotoxicity through miR-153/NF-E2-related factor 2/antioxidant response element signaling pathway

(2015) X.S. Zhang et al.   NEUROSCIENCE

Ginsenoside Rg1 protects against transient focal cerebral ischemic injury and suppresses its systemic metabolic changes in cerabral injury rats

(2015) Mingbao Lin et al.   Acta Pharmaceutica Sinica B

Nrf2 pathway activation contributes to anti-fibrosis effects of ginsenoside Rg1 in a rat model of alcohol- and CCl4-induced hepatic fibrosis

(2014) Jian-ping Li et al.   ACTA PHARMACOLOGICA SINICA

MicroRNA-144 is a circulating effector of remote ischemic preconditioning

(2014) Jing Li et al.   BASIC RESEARCH IN CARDIOLOGY

Ginsenoside Re Rescues Methamphetamine-Induced Oxidative Damage, Mitochondrial Dysfunction, Microglial Activation, and Dopaminergic Degeneration by Inhibiting the Protein Kinase Cδ Gene

(2014) Eun-Joo Shin et al.   MOLECULAR NEUROBIOLOGY

Posttreatment with 11-Keto-β-Boswellic Acid Ameliorates Cerebral Ischemia–Reperfusion Injury: Nrf2/HO-1 Pathway as a Potential Mechanism

(2014) Yi Ding et al.   MOLECULAR NEUROBIOLOGY

Ginsenoside Rg1 provides neuroprotection against blood brain barrier disruption and neurological injury in a rat model of cerebral ischemia/reperfusion through downregulation of aquaporin 4 expression

(2014) Yun Zhou et al.   PHYTOMEDICINE

Traumatic Brain Injury Dysregulates MicroRNAs to Modulate Cell Signaling in Rat Hippocampus

(2014) Liang Liu et al.   PLoS One

Sulforaphane preconditioning of the Nrf2/HO-1 defense pathway protects the cerebral vasculature against blood–brain barrier disruption and neurological deficits in stroke

(2013) Alessio Alfieri et al.   FREE RADICAL BIOLOGY AND MEDICINE

NRF2-regulation in brain health and disease: Implication of cerebral inflammation

(2013) Mats Sandberg et al.   NEUROPHARMACOLOGY

Neuroprotection After Stroke by Targeting NOX4 As a Source of Oxidative Stress

(2012) Kim A. Radermacher et al.   ANTIOXIDANTS & REDOX SIGNALING

The role of free radical generation in increasing cerebrovascular permeability

(2011) Paul A. Fraser   FREE RADICAL BIOLOGY AND MEDICINE

Nrf2-mediated induction of p62 controls Toll-like receptor-4-driven aggresome-like induced structure formation and autophagic degradation

(2011) K.-i. Fujita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

microRNA miR-144 modulates oxidative stress tolerance and associates with anemia severity in sickle cell disease

(2010) C. Sangokoya et al.   BLOOD

Expression of Keap1–Nrf2 system and antioxidative proteins in mouse brain after transient middle cerebral artery occlusion

(2010) Nobuhito Tanaka et al.   BRAIN RESEARCH