The Role of Astragaloside IV against Cerebral Ischemia/Reperfusion Injury: Suppression of Apoptosis via Promotion of P62-LC3-Autophagy

Combination of curcumin and vagus nerve stimulation attenuates cerebral ischemia/reperfusion injury-induced behavioral deficits

(2018) Jian Xu et al.   BIOMEDICINE & PHARMACOTHERAPY

Expression and role of autophagy-associated p62 (SQSTM1) in multidrug resistant ovarian cancer

(2018) Jinglu Wang et al.   GYNECOLOGIC ONCOLOGY

The Synergistic Neuroprotective Effects of Combined Rosuvastatin and Resveratrol Pretreatment against Cerebral Ischemia/Reperfusion Injury

(2018) Ying Liu et al.   Journal of Stroke & Cerebrovascular Diseases

Che-1 inhibits oxygen–glucose deprivation/reoxygenation-induced neuronal apoptosis associated with inhibition of the p53-mediated proapoptotic signaling pathway

(2018) Shenglong Guo et al.   NEUROREPORT

Autophagy in hemorrhagic stroke: Mechanisms and clinical implications

(2018) Haiying Li et al.   PROGRESS IN NEUROBIOLOGY

Preventive Effect of Low Intensity Pulsed Ultrasound against Experimental Cerebral Ischemia/Reperfusion Injury via Apoptosis Reduction and Brain-derived Neurotrophic Factor Induction

(2018) Chang-Mu Chen et al.   Scientific Reports

The Synergistic Neuroprotective Effects of Combined Rosuvastatin and Resveratrol Pretreatment against Cerebral Ischemia/Reperfusion Injury

(2018) Ying Liu et al.   Journal of Stroke & Cerebrovascular Diseases

Possible Involvement of PTEN Signaling Pathway in the Anti-apoptotic Effect of Electroacupuncture Following Ischemic Stroke in Rats

(2018) Ying Xing et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Ischemic Postconditioning Alleviates Cerebral Ischemia–Reperfusion Injury Through Activating Autophagy During Early Reperfusion in Rats

(2018) Yameng Sun et al.   NEUROCHEMICAL RESEARCH

Astragaloside IV represses high glucose-induced mesangial cells activation by enhancing autophagy via SIRT1 deacetylation of NF-κB P65 subunit

(2018) Xiaolei Wang et al.   Drug Design Development and Therapy

Buyang Huanwu Decoction Targets SIRT1/VEGF Pathway to Promote Angiogenesis After Cerebral Ischemia/Reperfusion Injury

(2018) Xia-Wei Zheng et al.   Frontiers in Neuroscience

USP14 inhibitor attenuates cerebral ischemia/reperfusion-induced neuronal injury in mice

(2017) Jia-Wei Min et al.   JOURNAL OF NEUROCHEMISTRY

Astragaloside IV protects against apoptosis in human degenerative chondrocytes through autophagy activation

(2017) Jianhong Liu et al.   Molecular Medicine Reports

Autophagy maintains the metabolism and function of young and old stem cells

(2017) Theodore T. Ho et al.   NATURE

Inhibition of cerebral ischemia/reperfusion injury-induced apoptosis: nicotiflorin and JAK2/STAT3 pathway

(2017) Guang-qiang Hu et al.   Neural Regeneration Research

Neuroprotection of agomelatine against cerebral ischemia/reperfusion injury through an antiapoptotic pathway in rat

(2017) Wijitra Chumboatong et al.   NEUROCHEMISTRY INTERNATIONAL

Neuroprotective effects of Kukoamine A on neurotoxin-induced Parkinson's model through apoptosis inhibition and autophagy enhancement

(2017) XiaoLong Hu et al.   NEUROPHARMACOLOGY

Astragaloside IV for Experimental Focal Cerebral Ischemia: Preclinical Evidence and Possible Mechanisms

(2017) Hui-Lin Wang et al.   Oxidative Medicine and Cellular Longevity

Focus Issue: Autophagy as hero and villain

(2017) Wei Wong   Science Signaling

Focus Issue: Autophagy as hero and villain

(2017) Wei Wong   Science Signaling

Rapamycin prevents cerebral stroke by modulating apoptosis and autophagy in penumbra in rats

(2017) Meiling Wu et al.   Annals of Clinical and Translational Neurology

Hexahydrocurcumin protects against cerebral ischemia/reperfusion injury, attenuates inflammation, and improves antioxidant defenses in a rat stroke model

(2017) Piyawadee Wicha et al.   PLoS One

Astragalus membranaceus: A Review of its Protection Against Inflammation and Gastrointestinal Cancers

(2016) Kathy K. Auyeung et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Neuroprotective effect of a novel Chinese herbal decoction on cultured neurons and cerebral ischemic rats

(2016) Fanny Chui-Fun Ip et al.   BMC Complementary and Alternative Medicine

Protective effects of propofol against whole cerebral ischemia/reperfusion injury in rats through the inhibition of the apoptosis-inducing factor pathway

(2016) Tao Tao et al.   BRAIN RESEARCH

Effects of Estrogen and Phytoestrogen Treatment on an In Vitro Model of Recurrent Stroke on HT22 Neuronal Cell Line

(2016) Javier Morán et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

The Autophagy Machinery Controls Cell Death Switching between Apoptosis and Necroptosis

(2016) Megan L. Goodall et al.   DEVELOPMENTAL CELL

Research review on the pharmacological effects of astragaloside IV

(2016) Lei Li et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Acute Ischemic Stroke Intervention

(2016) Priyank Khandelwal et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Potential neuroprotection of protodioscin against cerebral ischemia-reperfusion injury in rats through intervening inflammation and apoptosis

(2016) Xinxin Zhang et al.   STEROIDS

Erratum to: Neuroprotection and spatial memory enhancement of four herbal mixture extract in HT22 hippocampal cells and a mouse model of focal cerebral ischemia

(2015) Sung Min Ahn et al.   BMC Complementary and Alternative Medicine

Buyang Huanwu Decoction (BYHWD) Enhances Angiogenic Effect of Mesenchymal Stem Cell by Upregulating VEGF Expression After Focal Cerebral Ischemia

(2015) Junhong Yang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Silibinin Prevents Autophagic Cell Death upon Oxidative Stress in Cortical Neurons and Cerebral Ischemia-Reperfusion Injury

(2015) Min Wang et al.   MOLECULAR NEUROBIOLOGY

Ischemia/reperfusion-induced upregulation of TIGAR in brain is mediated by SP1 and modulated by ROS and hormones involved in glucose metabolism

(2015) Meiling Sun et al.   NEUROCHEMISTRY INTERNATIONAL

Raf/MEK/ERK can regulate cellular levels of LC3B and SQSTM1/p62 at expression levels

(2014) Jin-Hwan Kim et al.   EXPERIMENTAL CELL RESEARCH

The molecular and electrophysiological mechanism of Buyanghuanwu Decoction in learning and memory ability of vascular dementia rats

(2013) Tang Jinglong et al.   BRAIN RESEARCH BULLETIN

Autophagy variation within a cell population determines cell fate through selective degradation of Fap-1

(2013) Jacob M. Gump et al.   NATURE CELL BIOLOGY

Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy

(2013) Peter E. Czabotar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Autophagy regulates endoplasmic reticulum stress in ischemic preconditioning

(2012) Rui Sheng et al.   Autophagy

Astragalus Extract Alleviates Nerve Injury after Cerebral Ischemia by Improving Energy Metabolism and Inhibiting Apoptosis

(2012) Xiao-Ping Huang et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Clinical Efficacy and Safety of Buyang Huanwu Decoction for Acute Ischemic Stroke: A Systematic Review and Meta-Analysis of 19 Randomized Controlled Trials

(2012) Chi-zi Hao et al.   Evidence-based Complementary and Alternative Medicine

Astragaloside IV protects against focal cerebral ischemia/reperfusion injury correlating to suppression of neutrophils adhesion-related molecules

(2012) Min Li et al.   NEUROCHEMISTRY INTERNATIONAL

Activation of autophagy and Akt/CREB signaling play an equivalent role in the neuroprotective effect of rapamycin in neonatal hypoxia-ischemia

(2010) Silvia Carloni et al.   Autophagy

Autophagy activation is associated with neuroprotection in a rat model of focal cerebral ischemic preconditioning

(2010) Rui Sheng et al.   Autophagy

ER stress negatively regulates AKT/TSC/mTOR pathway to enhance autophagy

(2010) Liang Qin et al.   Autophagy

Osthole improves chronic cerebral hypoperfusion induced cognitive deficits and neuronal damage in hippocampus

(2010) Hai-Jie Ji et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Activation of Dopamine D4 Receptors Is Protective Against Hypoxia/Reoxygenation-Induced Cell Death in HT22 Cells

(2010) Saori Shimada et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Protective role of autophagy in neonatal hypoxia–ischemia induced brain injury

(2008) Silvia Carloni et al.   NEUROBIOLOGY OF DISEASE