Efficacy and Safety of Panax Notoginseng Saponins (Xueshuantong) in Patients With Acute Ischemic Stroke (EXPECT) Trial: Rationale and Design

Comparison of intramuscular and intravenous pharmacokinetics of ginsenosides in humans after dosing XueShuanTong, a lyophilized extract of Panax notoginseng roots

(2020) Hai-Yan Zhang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

(2020) Theo Vos et al.   LANCET

Stroke in China: advances and challenges in epidemiology, prevention, and management

(2019) Simiao Wu et al.   LANCET NEUROLOGY

Intravenous formulation of Panax notoginseng root extract: human pharmacokinetics of ginsenosides and potential for perpetrating drug interactions

(2019) Salisa Pintusophon et al.   ACTA PHARMACOLOGICA SINICA

Neuroinflammation: friend and foe for ischemic stroke

(2019) Richard L. Jayaraj et al.   Journal of Neuroinflammation

Mortality, morbidity, and risk factors in China and its provinces, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

(2019) Maigeng Zhou et al.   LANCET

Global brain inflammation in stroke

(2019) Kaibin Shi et al.   LANCET NEUROLOGY

National Institutes of Health Stroke Scale

(2019) Vicky Chalos et al.   STROKE

Guidelines for the Early Management of Patients With Acute Ischemic Stroke: 2019 Update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association

(2019) William J. Powers et al.   STROKE

Panax notoginseng Saponins Protect Cerebral Microvascular Endothelial Cells against Oxygen-Glucose Deprivation/Reperfusion-Induced Barrier Dysfunction via Activation of PI3K/Akt/Nrf2 Antioxidant Signaling Pathway

(2018) Shaonan Hu et al.   MOLECULES

Panax notoginseng Saponins Attenuate Oxygen–Glucose Deprivation/Reoxygenation-Induced Injury in Human SH-SY5Y Cells by Regulating the Expression of Inflammatory Factors through miR-155

(2018) Lanqing Meng et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Evaluating the protective mechanism of panax notoginseng saponins against oxidative stress damage by quantifying the biomechanical properties of single cell

(2018) Miaomiao Zhang et al.   ANALYTICA CHIMICA ACTA

Treatment and Outcome of Hemorrhagic Transformation After Intravenous Alteplase in Acute Ischemic Stroke: A Scientific Statement for Healthcare Professionals From the American Heart Association/American Stroke Association

(2017) Shadi Yaghi et al.   STROKE

Neuroprotection in acute stroke: targeting excitotoxicity, oxidative and nitrosative stress, and inflammation

(2016) Ángel Chamorro et al.   LANCET NEUROLOGY

Panax notoginseng saponins administration modulates pro- /anti-inflammatory factor expression and improves neurologic outcome following permanent MCAO in rats

(2016) Xiaowei Shi et al.   METABOLIC BRAIN DISEASE

Early Blood Brain Barrier Changes in Acute Ischemic Stroke: A Sequential MRI Study

(2015) Marc Giraud et al.   JOURNAL OF NEUROIMAGING

Protective effect of ginsenoside Rb1 on integrity of blood–brain barrier following cerebral ischemia

(2015) Wei Chen et al.   EXPERIMENTAL BRAIN RESEARCH

Very-late-antigen-4 (VLA-4)-mediated brain invasion by neutrophils leads to interactions with microglia, increased ischemic injury and impaired behavior in experimental stroke

(2014) Jens Neumann et al.   ACTA NEUROPATHOLOGICA

SPIRIT 2013 Statement: Defining Standard Protocol Items for Clinical Trials

(2013) An-Wen Chan et al.   ANNALS OF INTERNAL MEDICINE

Panax notoginseng saponins inhibit ischemia-induced apoptosis by activating PI3K/Akt pathway in cardiomyocytes

(2011) Shaoxian Chen et al.   JOURNAL OF ETHNOPHARMACOLOGY

Comparative study on saponin fractions from Panax notoginseng inhibiting inflammation-induced endothelial adhesion molecule expression and monocyte adhesion

(2011) Nan Wang et al.   Chinese Medicine

Inflammatory and Neuroimmunomodulatory Changes in Acute Cerebral Ischemia

(2009) David Brea et al.   CEREBROVASCULAR DISEASES

Panax notoginseng Reduces Atherosclerotic Lesions in ApoE-Deficient Mice and Inhibits TNF-α-Induced Endothelial Adhesion Molecule Expression and Monocyte Adhesion

(2009) Jian-Bo Wan et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY