Folium Ginkgo extract and tetramethylpyrazine sodium chloride injection (Xingxiong injection) protects against focal cerebral ischaemia/reperfusion injury via activating the Akt/Nrf2 pathway and inhibiting NLRP3 inflammasome activation

Notoginsenoside R1 Improves Cerebral Ischemia/Reperfusion Injury by Promoting Neurogenesis via the BDNF/Akt/CREB Pathway

(2021) Ting Zhu et al.   Frontiers in Pharmacology

Notoginsenoside R1 activates the NAMPT-NAD+-SIRT1 cascade to promote postischemic angiogenesis by modulating Notch signaling

(2021) Ting Zhu et al.   BIOMEDICINE & PHARMACOTHERAPY

Anti-ischemia/reperfusion injury effects of notoginsenoside R1 on small molecule metabolism in rat brain after ischemic stroke as visualized by MALDI–MS imaging

(2020) Ting Zhu et al.   BIOMEDICINE & PHARMACOTHERAPY

Xuesaitong injection (lyophilized) combined with aspirin and clopidogrel protect against focal cerebral ischemic/reperfusion injury in rats by suppressing oxidative stress and inflammation and regulating the NOX2/IL-6/STAT3 pathway

(2020) Ting Zhu et al.   Annals of Palliative Medicine

Tetramethylpyrazine attenuates blood-brain barrier disruption in ischemia/reperfusion injury through the JAK/STAT signaling pathway

(2019) Pian Gong et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

HMGB1-triggered inflammation inhibition of notoginseng leaf triterpenes against cerebral ischemia and reperfusion injury via MAPK and NF-κB signaling pathways

(2019) Xie et al.   Biomolecules

Advances in stroke pharmacology

(2018) Zhenhua Zhou et al.   PHARMACOLOGY & THERAPEUTICS

Notoginsenoside R1 ameliorates diabetic encephalopathy by activating the Nrf2 pathway and inhibiting NLRP3 inflammasome activation

(2018) Yadong Zhai et al.   Oncotarget

Systemic Inflammation and Cardiovascular Comorbidity in Psoriasis Patients: Causes and Consequences

(2018) Wolf-Henning Boehncke   Frontiers in Immunology

High serum sICAM-1 is correlated with cerebral microbleeds and hemorrhagic transformation in ischemic stroke patients

(2018) Bo-Na Wu et al.   BRITISH JOURNAL OF NEUROSURGERY

Vildagliptin Attenuates Hepatic Ischemia/Reperfusion Injury via the TLR4/NF-κB Signaling Pathway

(2018) Iman O. Sherif et al.   Oxidative Medicine and Cellular Longevity

Protective Effects and Target Network Analysis of Ginsenoside Rg1 in Cerebral Ischemia and Reperfusion Injury: A Comprehensive Overview of Experimental Studies

(2018) Weijie Xie et al.   Cells

Ginsenoside Rb1 and mitochondria: A short review of the literature

(2018) Ping Zhou et al.   MOLECULAR AND CELLULAR PROBES

Quercetin Attenuates Manganese-Induced Neuroinflammation by Alleviating Oxidative Stress through Regulation of Apoptosis, iNOS/NF-κB and HO-1/Nrf2 Pathways

(2017) Entaz Bahar et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Role of Oxidative Stress in Epigenetic Modification in Endometriosis

(2017) Fuminori Ito et al.   Reproductive Sciences

Ginsenoside compound K protects human umbilical vein endothelial cells against oxidized low-density lipoprotein-induced injury via inhibition of nuclear factor-κB, p38, and JNK MAPK pathways

(2017) Shan Lu et al.   Journal of Ginseng Research

Myricitrin Protects Cardiomyocytes from Hypoxia/Reoxygenation Injury: Involvement of Heat Shock Protein 90

(2017) Min Wang et al.   Frontiers in Pharmacology

Physiological roles of the mitochondrial permeability transition pore

(2016) Nelli Mnatsakanyan et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Astrocytes, therapeutic targets for neuroprotection and neurorestoration in ischemic stroke

(2016) Zhongwu Liu et al.   PROGRESS IN NEUROBIOLOGY

Endoplasmic reticulum stress-induced neuronal inflammatory response and apoptosis likely plays a key role in the development of diabetic encephalopathy

(2016) Zhouguang Wang et al.   Oncotarget

Astrocytes: a central element in neurological diseases

(2015) Milos Pekny et al.   ACTA NEUROPATHOLOGICA

Cell death disguised: The mitochondrial permeability transition pore as the c-subunit of the F1FO ATP synthase

(2015) Elizabeth A. Jonas et al.   PHARMACOLOGICAL RESEARCH

Suppression of NADPH oxidase- and mitochondrion-derived superoxide by Notoginsenoside R1 protects against cerebral ischemia–reperfusion injury through estrogen receptor-dependent activation of Akt/Nrf2 pathways

(2014) X. Meng et al.   FREE RADICAL RESEARCH

Notoginsenoside R1-mediated neuroprotection involves estrogen receptor-dependent crosstalk between Akt and ERK1/2 pathways: A novel mechanism of Nrf2/ARE signaling activation

(2014) X. Meng et al.   FREE RADICAL RESEARCH

Ginkgo Biloba Extract and Long-Term Cognitive Decline: A 20-Year Follow-Up Population-Based Study

(2013) Hélène Amieva et al.   PLoS One

Brain-Immune Interactions and Ischemic Stroke

(2012) Costantino Iadecola   ARCHIVES OF NEUROLOGY

Intranasal Ginsenoside Rb1 Targets the Brain and Ameliorates Cerebral Ischemia/Reperfusion Injury in Rats

(2011) Tingting Lu et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Calcium, ischemia and excitotoxicity

(2010) Kinga Szydlowska et al.   CELL CALCIUM

Brain angiogenesis in developmental and pathological processes: neurovascular injury and angiogenic recovery after stroke

(2009) Ken Arai et al.   FEBS Journal

Persistent redistribution of poly-adenylated mRNAs correlates with translation arrest and cell death following global brain ischemia and reperfusion

(2008) J.T. Jamison et al.   NEUROSCIENCE