Baicalin Attenuates Blood-Brain Barrier Disruption and Hemorrhagic Transformation and Improves Neurological Outcome in Ischemic Stroke Rats with Delayed t-PA Treatment: Involvement of ONOO−-MMP-9 Pathway
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Title
Baicalin Attenuates Blood-Brain Barrier Disruption and Hemorrhagic Transformation and Improves Neurological Outcome in Ischemic Stroke Rats with Delayed t-PA Treatment: Involvement of ONOO−-MMP-9 Pathway
Authors
Keywords
Baicalin, Hemorrhagic transformation, Ischemic stroke, Natural compound, Peroxynitrite, Tissue plasminogen activator
Journal
Translational Stroke Research
Volume -, Issue -, Pages -
Publisher
Springer Nature
Online
2017-12-23
DOI
10.1007/s12975-017-0598-3
References
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Note: Only part of the references are listed.- Therapeutic Strategies to Attenuate Hemorrhagic Transformation After Tissue Plasminogen Activator Treatment for Acute Ischemic Stroke
- (2017) Masato Kanazawa et al. Journal of Atherosclerosis and Thrombosis
- Baicalin Attenuates Subarachnoid Hemorrhagic Brain Injury by Modulating Blood-Brain Barrier Disruption, Inflammation, and Oxidative Damage in Mice
- (2017) Xianqing Shi et al. Oxidative Medicine and Cellular Longevity
- 12/15-Lipoxygenase Inhibition or Knockout Reduces Warfarin-Associated Hemorrhagic Transformation After Experimental Stroke
- (2017) Yu Liu et al. STROKE
- Baicalin alleviates ischemia-induced memory impairment by inhibiting the phosphorylation of CaMKII in hippocampus
- (2016) Peng Wang et al. BRAIN RESEARCH
- Executive Summary: Heart Disease and Stroke Statistics—2016 Update
- (2016) Dariush Mozaffarian et al. CIRCULATION
- One-Compound-Multi-Target: Combination Prospect of Natural Compounds with Thrombolytic Therapy in Acute Ischemic Stroke
- (2016) Han-Sen Chen et al. Current Neuropharmacology
- Caveolin-1 protects against hepatic ischemia/reperfusion injury through ameliorating peroxynitrite-mediated cell death
- (2016) Lei Gao et al. FREE RADICAL BIOLOGY AND MEDICINE
- A rationally designed rhodamine-based fluorescent probe for molecular imaging of peroxynitrite in live cells and tissues
- (2016) Tao Peng et al. Chemical Science
- Increased 12/15-Lipoxygenase Leads to Widespread Brain Injury Following Global Cerebral Ischemia
- (2016) Kazim Yigitkanli et al. Translational Stroke Research
- Peroxynitrite Decomposition Catalyst Reduces Delayed Thrombolysis-induced Hemorrhagic Transformation in Ischemia-reperfused Rat Brains
- (2015) Han-Sen Chen et al. CNS Neuroscience & Therapeutics
- Baicalin inhibiting cerebral ischemia/hypoxia-induced neuronal apoptosis via MRTF-A-mediated transactivity
- (2015) Wen-xia Zheng et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Serum Uric Acid Is Neuroprotective in Chinese Patients with Acute Ischemic Stroke Treated with Intravenous Recombinant Tissue Plasminogen Activator
- (2015) Xuan Liu et al. Journal of Stroke & Cerebrovascular Diseases
- Peroxynitrite decomposition catalyst prevents matrix metalloproteinase-9 activation and neurovascular injury after hemoglobin injection into the caudate nucleus of rats
- (2015) R. Ding et al. NEUROSCIENCE
- Serum Uric Acid Is Neuroprotective in Chinese Patients with Acute Ischemic Stroke Treated with Intravenous Recombinant Tissue Plasminogen Activator
- (2015) Xuan Liu et al. Journal of Stroke & Cerebrovascular Diseases
- Baicalin protects PC-12 cells from oxidative stress induced by hydrogen peroxide via anti-apoptotic effects
- (2014) Wen-xia Zheng et al. BRAIN INJURY
- Inhibition of Src phosphorylation reduces damage to the blood-brain barrier following transient focal cerebral ischemia in rats
- (2014) YONGSHENG BAI et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Flavocoxid, dual inhibitor of cyclooxygenase-2 and 5-lipoxygenase, exhibits neuroprotection in rat model of ischaemic stroke
- (2014) Dhirendra Pratap Singh et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Effects of Uric Acid Levels on Outcome in Severe Ischemic Stroke Patients Treated with Intravenous Recombinant Tissue Plasminogen Activator
- (2013) Sang-Hwa Lee et al. EUROPEAN NEUROLOGY
- Baicalin Attenuates Brain Edema in a Rat Model of Intracerebral Hemorrhage
- (2013) Qing-Bo Zhou et al. INFLAMMATION
- Hemorrhagic Transformation after Ischemic Stroke in Animals and Humans
- (2013) Glen C Jickling et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Baicalin can scavenge peroxynitrite and ameliorate endogenous peroxynitrite-mediated neurotoxicity in cerebral ischemia-reperfusion injury
- (2013) Mingjing Xu et al. JOURNAL OF ETHNOPHARMACOLOGY
- Matrix Metalloproteinases and Blood-Brain Barrier Disruption in Acute Ischemic Stroke
- (2013) Shaheen E. Lakhan et al. Frontiers in Neurology
- Baicalin attenuates proinflammatory cytokine production in oxygen–glucose deprived challenged rat microglial cells by inhibiting TLR4 signaling pathway
- (2012) Jincai Hou et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Baicalin Protects Mice From Staphylococcus aureus Pneumonia Via Inhibition of the Cytolytic Activity of α-Hemolysin
- (2012) Jiazhang Qiu et al. JOURNAL OF INFECTIOUS DISEASES
- The Effect of Baicalein on Hippocampal Neuronal Damage and Metalloproteinase Activity Following Transient Global Cerebral Ischaemia
- (2012) Jung-Hyun Lee et al. PHYTOTHERAPY RESEARCH
- Recommendations for Preclinical Research in Hemorrhagic Transformation
- (2012) Susan C. Fagan et al. Translational Stroke Research
- Baicalin reduces the permeability of the blood–brain barrier during hypoxia in vitro by increasing the expression of tight junction proteins in brain microvascular endothelial cells
- (2011) Haiyan Zhu et al. JOURNAL OF ETHNOPHARMACOLOGY
- Caveolin-1 regulates nitric oxide-mediated matrix metalloproteinases activity and blood-brain barrier permeability in focal cerebral ischemia and reperfusion injury
- (2011) Yong Gu et al. JOURNAL OF NEUROCHEMISTRY
- Effect of Baicalin on Matrix Metalloproteinase-9 Expression and Blood–Brain Barrier Permeability Following Focal Cerebral Ischemia in Rats
- (2011) Xian-kun Tu et al. NEUROCHEMICAL RESEARCH
- Baicalin attenuates focal cerebral ischemic reperfusion injury through inhibition of nuclear factor κB p65 activation
- (2010) Xia Xue et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Heart Disease and Stroke Statistics—2011 Update
- (2010) Véronique L. Roger et al. CIRCULATION
- Comparative pharmacokinetics of baicalin in plasma after oral administration of Huang-Lian-Jie-Du-Tang or pure baicalin in MCAO and sham-operated rats
- (2010) Ming-fei Zeng et al. FITOTERAPIA
- Baicalin Inhibits TLR2/4 Signaling Pathway in Rat Brain Following Permanent Cerebral Ischemia
- (2010) Xian-kun Tu et al. INFLAMMATION
- Peroxynitrite decomposition catalyst prevents matrix metalloproteinase activation and neurovascular injury after prolonged cerebral ischemia in rats
- (2010) Yalikun Suofu et al. JOURNAL OF NEUROCHEMISTRY
- Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials
- (2010) Kennedy R Lees et al. LANCET
- Baicalein is neuroprotective in rat MCAO model: Role of 12/15-lipoxygenase, mitogen-activated protein kinase and cytosolic phospholipase A2
- (2010) Lili Cui et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Uric Acid Levels Are Relevant in Patients With Stroke Treated With Thrombolysis
- (2010) S. Amaro et al. STROKE
- A Mouse Model of Hemorrhagic Transformation by Delayed Tissue Plasminogen Activator Administration After In Situ Thromboembolic Stroke
- (2010) Isaac García-Yébenes et al. STROKE
- Involvement of ROS in BBB dysfunction
- (2009) Pamela B. L. Pun et al. FREE RADICAL RESEARCH
- Neuroprotective Effect of Baicalin in a Rat Model of Permanent Focal Cerebral Ischemia
- (2009) Xian-kun Tu et al. NEUROCHEMICAL RESEARCH
- Normobaric Hyperoxia Reduces the Neurovascular Complications Associated With Delayed Tissue Plasminogen Activator Treatment in a Rat Model of Focal Cerebral Ischemia
- (2009) Wenlan Liu et al. STROKE
- Determination of baicalin in rat cerebrospinal fluid and blood using microdialysis coupled with ultra-performance liquid chromatography-tandem mass spectrometry
- (2008) H HUANG et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Normobaric hyperoxia inhibits NADPH oxidase-mediated matrix metalloproteinase-9 induction in cerebral microvessels in experimental stroke
- (2008) Wenlan Liu et al. JOURNAL OF NEUROCHEMISTRY
- Protecting Against Cerebrovascular Injury
- (2008) Guang Jin et al. STROKE
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